CURRICULUM VITAE CARL H. BACKES, M.D.

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1 CURRICULUM VITAE CARL H. BACKES, M.D. PRESENT TITLE AND AFFILIATION DUAL/JOINT APPOINTMENT Assistant Professor Department of Pediatrics The Ohio State University College of Medicine Attending Neonatologist Nationwide Children's Hospital Attending Cardiologist Nationwide Children's Hospital CITIZENSHIP AND VISA STATUS U.S. Citizen OFFICE ADDRESS Nationwide Children s Hospital Department of Pediatrics Section of Cardiology and Neonatology 700 Children s Drive Columbus, Ohio Office: (614) Carl.Backes@nationwidechildrens.org

2 EDUCATION UNDERGRADUATE EDUCATION 09/ /2001 Harvard University Bachelor of Arts GRADUATE EDUCATION 09/ /2006 Boonshoft School of Medicine Dayton, OH M.D. POST-GRADUATE EDUCATION & TRAINING 07/ /2008 Nationwide Children s Hospital/The Ohio State University 06/ /2011 Nationwide Children s Hospital/The Ohio State University 06/ /2013 Nationwide Children s Hospital/The Ohio State University Resident in Pediatrics Neonatology Fellowship Cardiology Fellowship ACADEMIC APPOINTMENTS 07/2006 present 07/2009 present 07/2010 present Instructor in Pediatrics Nationwide Children s Hospital/The Ohio State University Pediatric Resident Education Committee Nationwide Children s Hospital/The Ohio State University Principal Investigator, Center for Perinatal Research Nationwide Children s Hospital/The Ohio State University

3 STATE LICENSURE AND CERTIFICATIONS LICENSURE 2008 Ohio (active) CERTIFICATIONS 2010 present American Board of Pediatrics (certified) 6/28/2013 NRP (certified) 6/28/2015 HONORS AND AWARDS 06/2001 B.A. with High Honors (Magna Cum Laude) in Biology and Psychology Harvard University 06/2001 Senior Thesis entitled Biological Mechanism in Autistic Spectrum Disorders awarded High Honors Harvard University 09/ /2001 Member of Harvard Varsity Football and Lacrosse teams Harvard University 06/2006 Medical Humanism Award Boonshoft School of Medicine 06/2006 Pediatric Department Student of the Year Award: Top performance in pediatric clerkship 06/2008 Resident of the Year (Ohio State Medical Association) Nationwide Children's Hospital/The Ohio State University 07/2008 Accepted into the Pediatric Accelerated Program for Neonatology Fellowship Training Nationwide Children's Hospital/The Ohio State University 07/2010 Young Investigator Award American Academy of Pediatrics 2011 Meeting- Mead Johnson Award Nationwide Children's Hospital/The Ohio State University 06/2010 Fellow of the Year

4 Nationwide Children s Hospital/The Ohio State University 2012 Top Clinical Abstract Midwest Society of Pediatric Research (SPR): Given to top clinical abstract among junior faculty, fellows, and residents RESEARCH SUPPORT COMPLETED RESEARCH Internal CRI Grant Backes (PI) 2/1/2009 Delayed Umbilical Cord Clamping in the Extremely Low Birth Weight Neonate (ELBW): Effects on Endothelial Progenitor Cell (EPC) and Cytokine Levels The goal of this study is to evaluate the safety and efficacy of cord clamping among infants born extremely premature and evaluate potential biological mechanisms Principal Investigator: Backes 10,000 PEER REVIEWED Backes (PI) 7/1/2010 6/30/2013 Randomized, controlled trial of early versus delayed umbilical cord clamping in infants with congenital heart disease This is a prospective clinical trial evaluating whether delayed umbilical cord clamping is advantageous as compared with immediate cord clamping for infants who require early cardiothoracic surgery for palliation of a congenital heart lesion. We will evaluate clinical and biochemical variables to elucidate potential differences between the groups. Principal Investigator: Backes 135,000 PEER REVIEWED Backes (PI) 2/1/2011 Methadone Treatment: An Education-Based Initiative The goal of this study is to develop a comprehensive education program for pregnant women treatment for addiction Principal Investigator: Backes 35,000 PEER REVIEWED Backes (PI) 2/1/2012

5 Expanding the Outpatient Methadone Education Program: Are We Making a Difference? The funding priority that our grant addresses is to increase health education and information available to pregnant women who use alcohol or other drugs, and in this case are being treated with methadone. We will investigate if our efforts over the past year not only improve retention rates but also if it strengthens relationship between these at-risk women and their health care providers. Principal Investigator 35,000 PUBLICATIONS ARTICLES IN PEER REVIEWED JOURNALS 1. Jopperi-Davis K, Park MS, Rogers LK, Backes CH, Lim, IK, and Smith CV (2004). Compartmental inhibition of hepatic glutathione reductase activities by 1,3 bischloroethyl)-n-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344, Rats. Toxicology 147: Backes CH, Markham K, Moorehead P, Cordero L, Nankervis CA, Giannone PJ (2011). Maternal Preeclampsia and Neonatal Outcomes. Journal of Pregnancy 201, Backes CH, Martin EM, Nelin LD (2011). A Standardized Approach to the Care of the Infant Born at the Threshold of Viability. Neonatology Today. 97 (6) Backes CH, Moorehead PA. Nelin LD (2011). Cancer in Pregnancy: A Review of Fetal and Neonatal Outcomes. Clinical Obstetrics and Gynecology. 84 (2) Backes CH, Backes CR, Gardner D, Giannone PJ, Nankervis CA, Cordero L (2012). Neonatal Abstinence Syndrome (NAS): Transitioning Methadone Treated Infants From An Inpatient to an Outpatient Setting. Journal of Perinatology. 94 (2) Backes CH, Reber KM, Trittmann JK, Huang H, Tomblin J, Moorehead PA, Bauer JA, Smith CV, Mahan JD (2012). Fellow as Teachers: A Model to Enhance Pediatric Resident Education in the Neonatal Intensive Care Unit. Medical Education. 12 (1), Nist AR, Backes CH, Moorehead P, Wispe, J (2012). Current Controversies in Management of Neonatal Hypotension: A Multidisciplinary Approach. Advances in Neonatal Care. 14 (5), Markham K, Backes C, Samuels P (2012). Shigella during Pregnancy: Outcomes and Management. Clinical Obstetrics and Gynecology. 8 (23), Backes CH, Cua C, Kreutzer J, Armsby L, El-Said H, Moore J, Gauvreau K, Bergersen L, Holzer RJ (2012 Pending). Low weight as an independent risk factor for adverse events during cardiac catheterization of infants. Accepted for publication to Journal of Catheterization and Cardiovascular Interventions. 10. Backes CH, Nelin T, Gorr MW, Wold LE (2013). Early life exposure to air pollution: how bad is it? Toxicology Letters. 216(1),

6 ABSTRACTS 1. Backes CH, Jenniskens FA, Schorr EN, Rogers LK, Smith CV, Nowicki PT (2002). Oxidant stress and entothelin (ET1) expression occur in newborn, but not in older intestine after ischemia-reperfusion. Pediatric Research 51:139A. 2. Park MS, Backes CH, Jopperi-Davis KS, Rogers LK, and Smith CV (2002). Sex differences in compartmental expression of glutathione-dependent antioxidants in Fischer-344 rats. Pediatric Research 312A. 3. Backes CH, Schanbacher BL, Alcamo AM, Ackerman WE, Wold LE, Giannone PJ (2008). Particulate Matter (PM 2.5 ) Exposure on Placental Cell Viability in a Trophoblast Cell Line. Pediatric Research. 2838A Cordero L, Backes CH, Coley BD, Giannone PJ, Nankervis CA (2009). Needle Aspiration and Chest Tube Insertion for Pneumothorax in ELBW Infants. E-PAS Pediatric Research. 4346A Backes CR, Backes CH, Nankervis CA, Giannone PJ, Cordero L (2011). Neonatal Abstinence Syndrome (NAS): Transitioning Methadone Treated Infants From An Inpatient To An Outpatient Setting. E-PAS Pediatric Research. 4233A Breese LA, Backes CH, Gardikes R, Armstrong VL, Shepherd EG, Nelin, LD (2011). Implementation of a daily goal sheet in the neonatal intensive care unit (NICU): A nursing-led initiative to improve communication. E-PAS. Pediatric Research. 1233A: Backes CH, Ovunc B, Sarosh Batlivala S, Sthuthi D, Kollins K, Rome J, Bergersen L, Holzer R (2013). Death attributability in pediatric cardiac catheterization: a multi-center experience. Accepted American College of Cardiology. EDITORIALS AND REVIEW ACTIVITIES JOURNAL REVIEWER 07/ Present 08/ present Reviewer, Toxicology and Applied Pharmacology Reviewer, Congenital Heart Disease TEACHING AWARDS 07/2007 Ohio State Medical School Teaching Excellence Award (Given to 3 residents from a pool of 523 for excellence in clinical instruction as voted by medical students at The Ohio State University) The Ohio State University

7 LECTURES/PRESENTATIONS NATIONAL/INTERNATIONAL 10/2010 Postnatal Progenitor Cell Pools and Delayed Umbilical Cord Clamping at the Limits of Viability (Platform Presentation) American Academy of Pediatrics (AAP) San Francisco, CA 03/2012 Low weight as an independent risk factor for adverse events during cardiac catheterization of infants (Platform Presentation) Pediatric Interventional Cardiology Society (PICS) Chicago, IL 04/2012 Delayed umbilical cord clamping at birth decreases the incidence of severe intraventricular hemorrhage among low birth weight infants (Platform Presentation) American Academy of Pediatrics (AAP) 05/2012 Fellow as Teachers: Enhancing Resident Education in the NICU (Platform Presentation) Society of Pediatric Research Denver, CO 05/2013 Delayed umbilical cord clamping at the limits of Viability International conference: Neonatal Hemodynamics London, UK LOCAL/REGIONAL 01/2010 Mortality and Morbidity at the Limits of Viability: The Columbus Experience Obstetrics and Gynecology Grand Rounds The Ohio State University 03/2010 Neonatal Cardiology: The First 24 Hours Riverside Methodist Hospital (RMH) 05/2010 Hypotension in the Extremely Low Birth Weight (ELBW) Infant: Questions and Controversies National Neonatal Network Conference Cincinnati, OH 11/2011 Fellows as Teachers: A Model to Enhance Pediatric Resident Education Cleveland Clinic Cleveland, OH 05/2012 Using Pulse Oximetry to Screen for Congenital Heart Disease: A Needle in a Haystack National Neonatal Network Conference.

8 PROFESSIONAL MEMBERSHIPS AND ACTIVITIES 2007 present Alpha Omega Alpha (AOA) member: Medical Honors Society 2013 present American Heart Association (AHA) member, expires 6/30/2014

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