A method for simultaneous production and order planning in a cooperative supply chain relationship with flexibility contracts

Size: px
Start display at page:

Download "A method for simultaneous production and order planning in a cooperative supply chain relationship with flexibility contracts"

Transcription

1 roeeding of the 43rd Hawaii International Conferene on Sytem Siene A method for imultaneou odution and order lanning in a ooerative uly hain relationhi with flexibility ontrat obia Rut, Daniel Brüggemann Univerity of aderborn Deartment Buine Information Sytem aderborn, Germany obia.rut@hni.ub.de Daniel.Brueggemann@hni.ub.de Abtrat Nowaday a high lanning flexibility i required due to utomer-driven market and a riing number of odut variant. In ontext of a uly hain thi flexibility i alo imortant for the ourement of inut art from external ulier. In thi work a method for imultaneou odution and order lanning in a ooerative uly hain relationhi i eented. he method i art of an overall aoah whih trie to oordinate order quantitie of an inut art uing flexibility ontrat. hereby the inut art i delivered by two ulier for whih frame ontrat with quantity and quota agreement exit. he objetive i to guarantee thee quantitie in the frame ontrat horizon at minimum ot. A fine lanning aoah i eented whih lan the odution of the manufaturer imultaneouly with the order for the onidered inut art under onideration of iory defined flexibility orridor. 1. Introdution Cutomer-driven market along with a riing number of odut variant reult in high lanning unertainty and an inreaing demand of flexibility for manufaturer. o deliver odut in time and at low ot i a hallenging tak. When eential inut art of the end odut have to be urhaed thi alo lead to the need of flexibility in buyer-ulier relationhi. In the bet-ae a relationhi i ooerative and regard both buyer and ulier irumtane to reah an overall otimum for the artiiant. In traditional odution lanning firt the odution i lanned and afterward the required inut i alulated and ordered baed on the odution lan. By diregarding the interdeendenie between the ingle lanning te a otential to ave ot i wated. A aving ould be ahieved by imultaneou lanning whih neverthele alo inlude ome oblem. he firt oblem i that the effort to reah Wilhelm Dangelmaier, Dominik iker-huhzermeyer Univerity of aderborn Deartment Buine Information Sytem aderborn, Germany Wilhelm.Dangelmaier@hni.ub.de dh@mail.ub.de good olution an beome very high due to the inreaing omlexity of imultaneou lanning. he eond oblem i the unwillingne to hare data in a buyer-ulier relationhi. In thi work a method for imultaneou odution and order lanning in a ooerative uly hain relationhi i eented. o handle the omlexity oblem the order lanning aet i limited to one inut art and the oblem i olved heuritially. he method i art of an overall aoah whih trie to oordinate quantitie with flexibility ontrat. hereby the inut art i delivered by two ulier for whih frame ontrat with quantity and quota agreement exit. he aim i to guarantee thee quantitie in the frame ontrat horizon at minimum ot. he work i trutured a follow. Chater 2 introdue the onidered lanning enario and the referene to an overall aoah where the eented work i art of. Chater 3 range the aoah in the theory regarding odution lanning and quantity oordination. Chater 4 define the lanning a a mixed integer model. he heuriti olution for the lanning oblem i exlained in hater 5 before reult are hown in hater 6. Finally hater 7 give a ummary and an outlook on further work. 2. lanning ontext 2.1. lanning enario he uly hain enario in Figure 1 build the bai for the overall aoah. he utomer i a manufaturer whih odue finihed good and fae unertain demand of end onumer. He odue variant on one odution line whih an have a bottlenek art a inut. hi art i inluded in ome of the end odut, but not in all. All other inut art are diregarded, beaue it i aumed that they an eaily be odued or oured. he bottlenek art i /10 $ IEEE 1

2 roeeding of the 43rd Hawaii International Conferene on Sytem Siene oured from two ulier for whih frame ontrat with quota agreement exit. he oblem an eaily be extended by adding ulier or bottlenek art. uliera quota A inut bottlenekart odution utomer outut demand edited order quantity oordinated delivery quantity ulierb quota B aaity Figure 1. Conidered uly hain enario A atial examle for thi enario ould be a ar manufaturer who order headlight. hee headlight annot be odued by the manufaturer and have to be oured by two ulier for whih quota agreement exit. For ure a ar manufaturer need other imortant inut art, but we think that an overall ot redution an already be ahieved by intelligent lanning of eifi inut art. 2.2 Referene to overall aoah he introdued method i art of an overall aoah whih aim to reult in lower ot for the onidered uly hain etion. For thi a framework i neeary to lan the oured quantitie at lowet oible ot for the utomer and the ulier. he framework ontain ooerative arrangement whih ontrol the behaviour of the involved artie regarding order quantitie and ie. wo of thee arrangement are deribed in [1]. Aording to the flexibility of order the utomer and it ulier have ometing objetive. he utomer fae end utomer demand whih i uually known aoximately for near future, but unonfident for farther time eriod. Beaue of that unertainty the utomer need the oibility to hange it order aording to the demand he ha to fulfil. For hi uroe thi flexibility hould be a high a oible, but an dereae when a time eriod get nearer and foreat are relaed by real order. On the other hand the ulier want to have a aurate order lan a oible to avoid overaaitie and large tok. o handle thi oblem flexibility orridor are introdued (ee Figure 2).he figure how an examle of flexibility orridor for a eifi time egment and it hanging in time. In thi examle the edited order quantity doe not hange in time, o the utomer an jut onretize the orridor around the edited quantity. If thi quantity would hange the utomer would try to onretize orridor around the edited quantitie, but inide the old orridor. today hitory Figure 2. Flexibility orridor hi onet hould inreae the ulier afety in lanning. hereby the ulier hould be able to odue at lower ot whih they an give bak artly to their utomer by offering lower ie in ome time eriod. At the end all artie ould have a benefit. he utomer hould be enouraged to ommuniate hi future order early in time at high eiion. For that he ha to ay enalty ot for leaving the lanned orridor in a next rolling-horizon lanning. hereby two objetive are ahieved: he ulier get aid for unexeted adation of quantitie he utomer i willing to lan and oordinate the flexibility orridor a good a oible More information about flexibility orridor and a method whih lan the orridor an be found in [1]. he lanning i done in a rolling way and onit of a rough lanning and a fine lanning whih onretize the rough lanning (ee Figure 3).. eriod () fine lanning time egment (t) rough lanning + fine lanning Figure 3. Rolling rough and fine lanning he alulation of flexibility orridor i art of the rough lanning and lan quantitie for time egment whih ould be for examle month. he orridor are aggregated quantitie whih are an inut to the fine lanning whih lan onrete order for eriod whih are for examle day or week. he aoah eented in thi work i laed in the fine lanning art of the overall aoah. he utomer trie to lan hi odution and order imultaneouly regarding the ior defined flexibility 2

3 roeeding of the 43rd Hawaii International Conferene on Sytem Siene orridor and other influene with the objetive of ot minimization. hee order are the inut for the lat te in the aoah, a ofit-haring te where the ulier are able to ooe alternative delivery hedule and balane ayment. 3. Claifiation in theory 3.1. rodution lanning In lai odution lanning and ontrol ytem the lanning i done ueively. In a firt te the odution i lanned under the aumtion of unlimited aaity and the availability of all inut odut. Coneutively the aaitie are heked and the odution i lanned. Aording to thi odution lan order are determined for in-houe odution or for external ulier. A good overview of odution lanning an be found for examle in [2] and [3]. Some Advaned lanning ytem (AS) ue a imultaneou aoah to regard the different deendenie. he oblem of imultaneou lanning i the high omlexity of real world oblem whih make a olution in aoiate time often imoible. One oibility to olve thi omlexity oblem i to redue or divide the overall model into artial model. A detailed derition of AS ytem an be found in [4]. In ontext of thi work an aoah i eented whih doe a imultaneou lanning for the odution and the ordering of one inut fator neeary for the odution. o redue the omlexity thi i done in a big buket model where larger time eriod are ued o that ome event an be lanned in a ingle time eriod without lanning the equene of thee event. For further information about big buket model ee for examle [5] Coordinating mid-term quantitie Frame ontrat are often ued to determine right and reonibilitie of uly hain artner. A lot of different ontrat tye deal with ie and aaity agreement, buy bak reonibilitie, quantity flexibilitie and other toi. An overview of the different ontrat tye an be found in [6] and [7]. Quantity flexibility (QF) ontrat are widely ued in axi and build an intereting onet for the utomer-ulier-relation [8]. hey give the ulier a higher lanning aurane by defining quantitie at leat within a given bandwidth. he utomer i for examle a manufaturer who fae unertain demand and ovide the art ulier with a relenihment hedule whih beome the art ulier releae hedule. QF ontrat are defined between eah node. hey are arameterized by (α, β) whih lae bound on how the manufaturer an revie the relenihment hedule. All arameter are defined over time whereby the flexibility interval hould get ogreively maller the nearer a eriod get. A rolling horizon lanning with udated etimate i reeated eah eriod. Aording to [9] both artie will get a benefit and the QF ontrat an be treated a an anwer to the well-known bullwhi effet. he ulier ha to over any requet u to the maximum of the flexibility bound giving the utomer a afety buffer. On the other ide the utomer agree on the lower bound a a minimum quantity and therefore give the ulier a higher afety in lanning. he flexibility ontrat ued in the aoah of thi work are very imilar to the QF ontrat. Some additional rule were defined to oordinate the quantitie aording to different time area. hee time area are deribed in [1] Coordinating hort-term quantitie In the mid-term lanning only aggregated quantitie are lanned whih have to be onretized in hort-term lanning. Even if the mid-term quantitie were oordinated well the exat order an be ubotimal for the ulier if their ituation are diregarded. In literature an integrated lanning and ourement i often ooed to reah a good overall olution. hi integrated lanning oordinate the odution oliy of a ulier with the ordering oliy of a utomer and an either be done imultaneouly or ueively. Simultaneou aoahe an be found for examle in [10] and [11]; ueive aoahe in [12] and [13]. A lit of more aoahe an be found in [14] and [15]. hee aoahe reah good reult, but are not well aliable for thi work. he differene of the aoah of our work to integrated lanning and ourement i that the utomer lan hi odution and the required order imultaneouly onidering the flexibility orridor. he imultaneou aet i between the utomer odution and hi ourement and not between the utomer ourement and the ulier odution. In thi work the fine lanning of the utomer i influened by different ie whih are offered by the ulier for ingle time eriod. So the ulier an affet the order behaviour of the utomer under onideration of their aaity ituation. A final ofitharing te hould give the ulier the oibility to ahieve another ot redution by offering alternative odution hedule. 3

4 roeeding of the 43rd Hawaii International Conferene on Sytem Siene Uing thi aoah the utomer i able to lan it odution and it ourement imultaneouly whih hould reult in ot redution. At the ame time the ot truture of the ulier i regarded by the ie for ingle eriod and the final te of ofit-haring. hi i done in ingle te to redue the omlexity of the overall oblem. 4. Mathematial model After introduing ome imortant aumtion the arameter and variable are lited before the model i introdued. Imortant aumtion for the model are: here are two different kind of odut: the bottlenek odut (BR) ontaining a bottlenek art (BA) and the non-bottlenek odut, whih do not ontain thi art. Every BA and BR generate the ame torage ot. Eah BR ontain one idential BA. Delivery time are zero (will be added in future work). Setu ot are equene indeendent. able 1 and able 2 lit the arameter and variable whih are onidered in the model. able 1: arameter of mathematial model arameter Meaning Number of time egment Number of eriod Number of eriod er time egment r Set of odut S Set of ulier var rie of ulier for one BA in eriod fix Fixed order ot of ulier in eriod max Maximum of deliverable BA unit for ulier in eriod max Maximum of deliverable BA unit for t, ulier in time egment t LB Lower bound of flexibility orridor of t, ulier in time egment t UB Uer bound of flexibility orridor of t, ulier in time egment t unihment ot for violating the flexibility t, orridor of ulier in time egment t er unit D b d SI C SO C Delay ot er eriod and BR unit Binary arameter indiating if odut i a BR (1) or a non-br (0) Cutomer demand for odut in eriod Storage aaity for BA Storage aaity for BR SI SO SC C CD dl Storage ot er BA unit Storage ot er BR unit Setu ot for odut in eriod rodution aaity in eriod Caaity demand for one unit of odut Binary arameter indiating if delayed delivery i ermitted (1) or not (0) able 2: Variable of the mathematial model Variable Meaning l Lot ize of odut in eriod dv Number of delivered unit of odut in eriod dl Number of delayed unit of odut in eriod Ordered BA amount at ulier in eriod o BA t Number of BA tored in eriod BR t Number of tored unit of odut in eriod l Binary variable indiating if an order at ulier i laed in eriod (1) or not (0) UB df Amount of BA exeeding the uer bound of t, the flexibility orridor of ulier in time egment t LB df Amount of BA fall below the lower bound of t, the flexibility orridor of ulier in time egment t e Binary variable indiating if a etu i required to odue odut in eriod (1) or not (0) he aim of the deribed method i the ot minimization of the utomer. he goal funtion i a follow: Minimize Z = SI BA ( t + = 1 SO BR D SC t, dl,, e, r var fix (, o, +, l, )) + S UB LB ( dft, t, + dft, t, ) t= 1 S ( + + ) + he following ot are regarded: Storage ot for BA and BR Cot for delayed delivery Setu ot Variable and fixed order ot Cot for violating the flexibility orridor (1) o get a valid olution the following ontraint have to be fulfilled: 4

5 roeeding of the 43rd Hawaii International Conferene on Sytem Siene BA 0 t BA ( t + t + dl ) = 0 (2) r + t + BR BA 0,, 0, l,, C e CD = 1,... (19) r t BA SI = 1,... (3) BR SO ( t ) = 1,... (4) r o max t = ( t 1) + 1 ( o ) max I = 1,... S (5) t = 1,... S (6) ( l CD) C = 1,... (7) r BR + t l dl d ( l ) ( d ) = 1 = 1 = 1 = 1 = 1,... r (8) r (9) ( dv ) ( d ) r (10) o l max BA + 1 r = 1,... (11) S ( o t ) ( l b ) = 1,... (12) S t ( o ) ( l b ) BA -1 + S r = t BA = 1,... (13) Contraint (2) initialize the reurively defined variable with zero and the following two ontraint limit the torage utilization to the aaity in eah eriod. Contraint (5) and (6) limit the amount of BA ordered at the artiular ulier to the maximum limit of the eriod reetively the time egment. Contraint (7) aure that the required odution aaity never exeed the available aaity in any eriod. he next two ontraint are imortant for atifying the demand. he firt one enfore that eah demand an be atified by the odut unit whih have been odued u to the artiular demand eriod, if delayed delivery i forbidden. Otherwie thi ontraint i ignored. he other ontraint ha a imilar truture but onider the whole lanning horizon. hereby it i guaranteed that every demand i atified at the end of the lat time egment if a valid olution an be found. Contraint (10) atifie the imilar funtion for the delivery variable. he next ontraint fore the value of the binary lae-variable aording to the order. Contraint (12) enure that the available volume of BA unit i high enough for the lanned odution in eah eriod. he next two ontraint are the tok balane ontraint for both torage tye. Contraint (15) and (16) are imortant for determining the variane of the order amount from the flexibility orridor. Contraint (17) and (18) are neeary for etting the value of the variable ounting the odution delay to the aurate value. Contraint (19) et the binary etu variable to one, if at leat one odut i odued and et an uer bound for the lot ize. BR BR -1, + = t l dv t t LB t, ( ) t, = ( t 1) + 1 LB o df t = ( t 1) + 1 2= 1 UB t, t, ( o ) UB df ( d l ) dl 2, 2, dl dl dv + d 1, = 1,... r (14) t = 1,... S (15) t = 1,... S (16) = 1,... (17) = 1,... r (18) 5. he method 5.1. Main idea he main objetive of the introdued method i to find a feaible and good olution onerning the reulting overall ot by following iterative te. he algorithm onit of a ontrutive art and everal imoving method wherea ome of thee method are exeuted during the ontrutive alulation and ome of them try to imove the reult after a firt olution for the given oblem ha been found. Due to age retrition only the ontrutive art i deribed. he idea of the method i to tart with an emty lan and alway add the bet lot to the odution lan until all demand are fulfilled. hereby the 5

6 roeeding of the 43rd Hawaii International Conferene on Sytem Siene determination of the lot onider all relevant information like the ulier and the uly eriod in ae of a bottlenek odut. o learly define the information whih i needed to deribe the manufaturing of one odut the term odution i introdued. A odution ha to ontain the following information: 1. Suly eriod of the BA 2. rodution eriod 3. Demand eriod 4. rodued odut 5. Sulier for the BA 6. Lot ize he oeration are alway the ame: In eah te the method trie to find a odution whih reult in minimal ot in the artiular ituation. A it ha been deribed in art four, there are everal different ot whih have to be onidered imultaneouly, like for examle torage, delay or etu ot. o afford the eented oe of hooing the loally bet odution in an iterative way, there mut be a way to etimate the ot er odut whih will exetedly our by adding the hoen tule to the reulting lan. Furthermore there mut be a data truture to generate and tore the oible odution and to determine the artiular bet one in an effiient way. hi data truture i a eriodially udated die whih ontain all available odution and the ot etimation. he next etion will deribe thi truture in detail Data truture he data truture to tore and analye the oible odution in the artiular ituation i a threedimenional truture, alled ot die (ee Figure 4). Suly eriod Demand eriod Cot die element: - Etimated ot - Sulier - rodut grou Figure 4. Cot die he dimenion are the three different temoral fator, whih influene the lanning and imlementation of the odution lan: 1. Suly eriod 2. rodution eriod 3. Demand eriod hereby the truture an tore a odution and it relevant value for eah ombination of the three different timetam. he die ontain die element, whih tore the remaining item of the odution tule. o kee the ot alulation imle the odued odut i not determined and tored during the alulation oe but during the odution hoie in the ontrutive algorithm. herefore the die element imly tore if the artiular etimated ot value doe aume the odution of a BR or a non-br. hi imlifiation to inreae the effiieny of the method i valid beaue the ot of all BR and non-br are imilar aording to the aumtion in hater 4. lanning a large amount of eriod onequently lead to a large and omlex data truture, whih might be ineffiient to handle. Beaue of thi the die i ut to a manageable ize by removing illegal or uele element Calulation and udate of ot die value o alway determine the bet odution in the artiular ituation the value of the die element mut be alway u to date. he following etion will exlain how the etimated ot of a die value are alulated and when they have to be udated Calulation of ot die value he ot value of the die element alway reeent the ot er odut whih might our if a ingle element of the artiular odution i added to the reult. Before alulating the ot the algorithm ha to erform ome hek to determine if a odution of the die element i till oible. hi i neeary beaue ome element an beome imoible, beaue other odution were lanned before whih influene for examle torage or odution aaity. If at leat one ondition i violated the etimated ot value an be et to without erforming any more alulation. Otherwie all different ot mut be examined for the artiular odution. In the following exlanation the alulation of the ot for the uly eriod lying in time egment t, the odution eriod and the demand eriod d i aumed. he different ot are onidered: 1. unihment ot for violating the flexibility orridor of the ulier he unihment ot, d, are the minimum of the unihment ot of all known ulier in the, du,, artiular time egment: = min( u S ) (20),d {, d, u } 6

7 roeeding of the 43rd Hawaii International Conferene on Sytem Siene ,d,u = { t tu,, ( u, ) tu, = ( t-1) + 1 if o < LB t t, u, (, u ) t, u = ( t-1) + 1 if o UB 0, otherwie (21) he unihment ot are a aving if an order would hel to reah the flexibility orridor. Otherwie the ot are zero if the flexibility orridor ha already been reahed or they are oitive if the uer bound of the etor ha been exeeded. 2. Storage ot he ordered BA a well a the odued BR have to be tored whih lead to the torage ot S of the odution: S SI SO = ( ) + max(0,( d )) (22) 3. Fixed order ot he fixed order ot F, d, are general ot and not alied to one ingle odut unit. herefore the fixed order ot are unitized to one odut unit by dividing them through the etimated amount AM of, d, odued odut unit. How thi amount i determined will be exlained in etion fix F, u,d = (23) AM,d 4. Variable order ot he variable order ot are the ie of the BA. Beaue of the goal of ot minimization the heaet ulier i hoen and the variable ot V, d, are onequently the minimum of all available ie: V var = min( u S ) (24),d {, u } 5. Delay ot If delayed delivery of the odut to the utomer i ermitted a odution might lead to delay ot D :, d, D D = max(0,( d )) (25),d 6. Setu ot A it ha been already mentioned the etu ot S, d, are equene indeendent and therefore eay to quantify. he only oblem i that the algorithm doe not know whih odut will be odued when thi odution i hoen o the etimated etu ot are determined by alulating the average etu ot of all odut: S S r,d = (26) r After alulating the value of the different ot the etimated ot value of the die element an be, d, determined: S F V D S = (27),d d,, d,, d,, d,, d,, Udate of ot die value after adding a odution to the reult After adding a odution of the ot die to the reult there might be the need to udate everal die element. hi udate deend on the following ondition. 1. Ued die element he ontrutive algorithm determine the oduable amount by uing everal retrition. herefore at leat one of the everal different bound ha been reahed and an udate i onequently neeary for thi element. 2. Firt order of the ulier If the added odution ha oened a new order at a artiular ulier all die element with the uly eriod have to be udated beaue the fixed order ot an be removed from the alulation. Of oure thi aume that the order limit of that ulier ha not been reahed yet. 3. All demand are atified If the added odution ha atified the omlete demand in eriod d of all odut of the ued bottlenek oerty all field with the demand eriod d have to be udated beaue the etimated ot will hange due to the hange of the examined odut et. 4. Order limit of the ulier ha been reahed If the added odution ha the onequene that the order limit of the ulier in the examined eriod or time egment ha been reahed, all die element with the ued uly eriod, or even all element with a uly eriod lying in the affeted time egment, have to be udated. hi i neeary beaue another ulier with different ot ha to be hoen. 7

8 roeeding of the 43rd Hawaii International Conferene on Sytem Siene Storage aaity ha been reahed If the added odution ha reahed the aaity limit of either the odut or the art torage the ot of the die element, whih ue thi bottlenek eriod in their odution, an be et to. 6. rodution aaity ha been reahed If the added odution ha dereaed the odution aaity in eriod to a value whih i not a high a at leat one of the odut of the examined bottlenek oerty demand, the die element of the odution eriod have to be udated. he udate will either hooe the other odut et or et the ot value to. If a odution i removed whih i the ae in an iterative te the udate oedure i imilar Contrutive algorithm Figure 5 how the general truture of the ontrutive algorithm for finding a firt feaible olution for the given oblem. [another demand to fulfill and oblem feaible to thi oint] hooe next utomer demand determine bet odution for artiular ituation determine fitting odut with greatet lot ize add odut to reult udate ot die aly iterative algorithm whih have to be exeuted during ontrution [all demand atified or oblem infeaible] Figure 5. Contrutive algorithm he following two ubetion exlain the main tak of the ontruting algorithm in detail Find the bet odution in the ot die Due to the fat that the minimal ot an be found in every legal die element the algorithm ha to examine every element of the die. An imovement of exeution eed an be ahieved by jut examining a defined amount of intelligent or randomly hoen die element, but thi of oure an lead to a dereaed quality or, in ome ae, to the reult, that the oblem i infeaible although a feaible olution ould be found. Neverthele the algorithm trie to find the odution in the die with minimal ot er unit of all element whih are taken into aount. If there are everal odution with the ame ot a rule deide about the hoie of the odution. he reult of thi oe i the odution-6-tule whih ontain all information about the next te for determining the odut and lot ize. hi oe i deribed in the next ubetion Determine the oduable odut and it lot ize After identifying the odution whih hould be added to the reult in the firt te of the iteration, the algorithm now trie to determine the odut, whih hould be odued and it lot ize. he objetive i to atify the utomer demand a far a oible o the odut with the greatet lot ize will be hoen for the odution. hereby the odut grou indiated by the die element mut be onidered in thi evaluation. he lot ize of a odution with uly eriod in time egment t, odution eriod and demand eriod d ha the following uer bound: 1. Demand Beaue tok holding hould be avoided the demand d of odut in eriod d i one limitation for the d, lot ize. 2. rodution aaity he oduible amount deending on the available odution aaity in the artiular eriod and the aaity requirement of one odut unit i another uer bound for the lot ize. he aaity bound CB for the odut in the odution eriod i defined a: C CB = (27) CD 3. Storage aaity he aaity of the BA tok S, a CA in the eriod between the uly and odution eriod a well a the aaity of the BR tok S, CA in the eriod between the odution and demand eriod may not be exeeded. So they reeent a limitation for the lot ize: S,, min min ( S a ); min ( S CB,d = CAi CAi ) (28) i [; 1] i [ ; d 1] 8

9 roeeding of the 43rd Hawaii International Conferene on Sytem Siene Maximum order limit he aaitie of the heaet ulier, whih ha been determined in the firt te may not be exeeded for the uly eriod. hi alie for the eriod O, LC u and the time egment O, LC. So thee value reeent tu, an uer bound for the lot ize: O, LC = max o (29) u, u, u O, t t, u, u, u = ( t 1) + 1 LC = max ( o ) (30) 5. Flexibility orridor bound he flexibility orridor bound have an influene on the lot ize beaue exeeding the lower or uer bound hange the etimated ot of one odut unit and thereby ut the loal otimality of the hoen odution in quetion. he order limit CS L tu, for the time egment t i defined a: o t = ( o ) (31) = ( t 1) + 1, u LBtu, o CS t,u = t, u L UB o,if o < LB tu, tu, < tu,,if LB o UB,if o UB tu, (32) he lot ize LS of a odut for the eriod, d,, determined in the firt te of the iteration i the minimum of the alulated limitation: LS,d, = S O, O, CS (33) min( d ; CB ; CB ; LC ; LC ; L ) d,, d u t, u t, u he lot ize LS of the odution and the odued, d, odut an now be identified by maximizing thi value over all odut belonging to the examined odut grou: =argmax ( LS ) (34) LS r, d,, d,,, d, = LS (35) All neeary information for the new odution ha been determined. he eond te of the iteration ha finihed and the new odution an now be added to the reult et. hi oe will be reeated until a valid olution i found or until the infeaibility of the oblem i identified. 6. Reult An imlementation of the eented algorithm and oee ha been reated to demontrate their ability to find good olution in many different enario. We ued the mathematial model eented in etion 4 and imlemented it in the otimizer MOS [16] to benhmark the method reult with the otimal reult. he imlementation in the urrent tate ha the target to demontrate the quality of the reult and i not yet otimized onerning the runtime. able 3 eent the enario whih have been ued to omare the method with the otimal value. able 3: et enario S r / Seiality =4; = =4; =2 fored unihment =5; =1 fored delay =4; = =40; = =50; =10 torage bottlenek =100; =20 Column S indiate how many ulier were regarded, olumn r the number of odut, olumn / the number of eriod and time egment and the lat olumn how if a eial demand ituation wa analyzed. hee enario odue the reult in able 4 whih eent the omutation time and overall ot of the mathematial olver and the method. able 4. et reult Solver Method ime () Cot ime () Cot 1 < < < < < < he reult demontrate the following fat: 1. he quality of the overall ot reult i very good in omarion to the otimal value. 2. he imlementation of the deribed method wa fater, even if the algorithm i not yet otimized for runtime. 9

10 roeeding of the 43rd Hawaii International Conferene on Sytem Siene Conluion In thi work an aoah for a imultaneou odution and order lanning in a ooerative uly hain relationhi wa eented. Firt a derition of the lanning enario and the referene to an overall method wa given. Afterward the work wa laified in the theory of odution lanning and quantity oordination. A mathematial model wa develoed that enable an otimal olution and an be ued a a benhmark for the heuriti method whih wa introdued in detail. Firt reult were eented whih how a very good quality of the eented aoah. Additionally to the eented method we have alo imlemented ome imovement method whih try to find a better olution after a valid lan wa found. hee method ahieve imoved reult by hanging ingle odution, but were not deribed in thi work due to age retrition. In ontext of the overall rolling lanning the deribed method will be ued both for new lanning and for hange lanning. In hange lanning odution whih need to be relanned will be identified, deleted and lanned again aording to the value of the ot die. At the moment we are working on the onjuntion of the rough lanning and the fine lanning to automatially lan the flexibility orridor, the order and the odution lanning in a rolling way. hi lanning will run for the whole frame ontat horizon and will be benhmarked with an otimal olution for whih a mathematial model wa already develoed. 8. Referene [1]. Rut, W. Dangelmaier, D. Brüggemann, J.-. ater: An aoah for flexible utomer-ulier relationhi with fixed delivery ontrat and quota agreement. In: roeeding of the 13 IFAC Symoium on Information Control roblem In Manufaturing, Moow, Ruia, Elevier Siene, 2009, [2] E. A. Silver, D. F. yke, and R. eteron, Inventory Management and rodution lanning and Sheduling, 3 rd Edition, John Wiley In., New York, [3] L. J. homa, J. O. MClain, An overview of rodution lanning, In: Handbook in Oeration Reearh and Management Siene, Volume 4, Logiti of rodution and Inventory, edited by S. C. Grave, A. H. G. Rinnoy Kan and. H. Zikin, Elevier Siene ubliher, Amterdam, 1993, [4] H. Stadtler, C. Kilger, Suly Chain Management and Advaned lanning: Conet, Model, Software, and Cae Studie, 4 th Edition, Singer-Verlag, Berlin, [5] D. Quadt, Lot-Sizing and Sheduling for Flexible Flow Line, Leture Note in Eonomi and Mathematial Sytem, Singer-Verlag, Berlin, [6] A. Gomez-adilla, J. Duvallet and D. Llerena, Contrat yology a a Reearh Method in Suly Chain Management In: Kotzab, H. (ed.), Reearh Methodologie in Suly Chain Management, hyia-verlag, Heidelberg. 2005, [7] C. Keinger, H. ieer, Managing Rik with Strutured Suly Agreement In: C. An, H. Fromm (ed.), Suly Chain Management on Demand, Singer-Verlag, Berlin, 2005, [8] A.A. ay, W.S. Lovejoy. Quantity flexibility ontrat and uly hain erformane. Manufaturing and Servie Oeration Management, 1, 2, 1999, [9] H.L. Lee, V. admanabhan and S. Whang, he bullwhi effet in uly hain. Sloan Management Review, 38, 3, [10] S.K. Goyal, An integrated inventory model for a ingle ulier ingle utomer oblem. In: International Journal of rodution Reearh, 1976, Vol. 15, No. 1, [11] A.K. Agrawal, D.A. Raju, Imoved joint eonomi lot ize model for a urhaer and a vendor. In M. Khan, C.S. Wright and R. Whalley: Advaned Manufaturing roee, Sytem and ehnologie (AMS96), London, [12] J.. Monahan, A Quantity Diount riing Model to inreae Vendor rofit. In: Management Siene, 1984, Vol. 30, No. 6, [13] H.L. Lee, M.J. Roenblatt, A Generalized Quantity Diount riing Model to Inreae Sulier rofit. In: Management Siene, 1986, Vol. 32, No. 9, [14] E. Suky, Koordination in Suly Chain: Sieltheoretihe Anätze zur Ermittlung integrierter Betellund roduktionolitiken,wiebaden, [15] E. Suky, Coordinated order and odution oliie in uly hain. OR Setrum 26, 2004, [16] U. Suhl, (2000), MOS Mathematial Otimization Sytem, OR New, 8, 2000,

1-Methylcyclopropene Impurities. GC method. CIPAC Collaborative Trial according to CIPAC Information Sheet Number 282

1-Methylcyclopropene Impurities. GC method. CIPAC Collaborative Trial according to CIPAC Information Sheet Number 282 1-Methylylopropene Impuritie GC method CIPAC Collaborative Trial aording to CIPAC Information Sheet Number 282 D. Verona AgroFreh, In. 727 Norritown Road Spring Houe, Pa. 19477 United State April 2009

More information

Deaf-Mute Students Physical Health Development Strategy Research in the Perspective of Education Fair Equalization

Deaf-Mute Students Physical Health Development Strategy Research in the Perspective of Education Fair Equalization Send Orders for Rerints to rerints@benthamsiene.ae 1640 The Oen Cybernetis & Systemis Journal, 015, 9, 1640-1645 Oen Aess Deaf-Mute Students Physial Health Develoment Strategy Researh in the Persetive

More information

FPGA-based Low Latency Inverse QRD Architecture for Adaptive Beamforming in Phased Array Radars

FPGA-based Low Latency Inverse QRD Architecture for Adaptive Beamforming in Phased Array Radars RADIOENGINEERING, VOL. 6, NO. 3, SEPTEMBER 07 85 FPGA-baed Low Lateny Invere QRD Arhiteture for Adaptive Beamforming in Phaed Array Radar Raafia IRFAN, Haroon ur RASHEED, Waqa Ahmed TOOR Dept. of Eletrial

More information

Protein Structure Prediction using 2D HP Lattice Model Based on Integer Programming Approach

Protein Structure Prediction using 2D HP Lattice Model Based on Integer Programming Approach 212 International Congre on Informatic, Environment, Energy and Application-IEEA 212 IPCSIT vol.38 (212) (212) IACSIT Pre, Singapore Protein Structure Prediction uing 2D HP Lattice Model Baed on Integer

More information

Sequence Analysis using Logic Regression

Sequence Analysis using Logic Regression Geneti Epidemiology (Suppl ): S66 S6 (00) Sequene Analysis using Logi Regression Charles Kooperberg Ingo Ruzinski, Mihael L. LeBlan, and Li Hsu Division of Publi Health Sienes, Fred Huthinson Caner Researh

More information

EXPLORING COGNITIVE STRATEGIES FOR INTEGRATING MULTIPLE-VIEW VISUALIZATIONS

EXPLORING COGNITIVE STRATEGIES FOR INTEGRATING MULTIPLE-VIEW VISUALIZATIONS EXPLORING COGNITIVE STRATEGIES FOR INTEGRATING MULTIPLE-VIEW VISUALIZATIONS Young Sam Ryu 1, Beth Yot 2, Gregorio Convertino 2, Jian Chen 2, and Chri North 2 Grado Department of Indutrial and Sytem Engineering

More information

The Design of Low Pass Filter with Active Filter based on Complex Surroundings Changhai Li 1, a Su Ye 2 Zhihui Sun 1 Yuantao Yu 1

The Design of Low Pass Filter with Active Filter based on Complex Surroundings Changhai Li 1, a Su Ye 2 Zhihui Sun 1 Yuantao Yu 1 International onerence on Automation, Mechanical ontrol and omutational Engineering AME 5 The Deign o Low Pa Filter with Active Filter baed on omlex Surrounding hanghai Li, a Su Ye Zhihui Sun Yuantao Yu

More information

Effect of Curing Conditions on Hydration Reaction and Compressive Strength Development of Fly Ash-Cement Pastes

Effect of Curing Conditions on Hydration Reaction and Compressive Strength Development of Fly Ash-Cement Pastes Effet of Curing Conditions on Hydration Reation and Development of Fly Ash-Cement Pastes Warangkana Saengsoy Candidate for the degree of Dotor of Philosophy Supervisor: Prof. Dr. Toyoharu Nawa Division

More information

CCXCIII. VITAMIN A DETERMINATION: RELA- AND PHYSICAL METHODS OF TEST. TION BETWEEN THE BIOLOGICAL, CHEMICAL

CCXCIII. VITAMIN A DETERMINATION: RELA- AND PHYSICAL METHODS OF TEST. TION BETWEEN THE BIOLOGICAL, CHEMICAL CCXCIII. VITAMIN A DETERMINATION: RELA- TION BETWEEN THE BIOLOGICAL, CHEMICAL AND PHYSICAL METHODS OF TEST. BY KATHLEEN CULHANE LATHBURY. From the Phyiological Laboratorie, The Britih Drug Houe, Ltd. (Received

More information

THE TYCHE AND SAFE MODELS: COMPARING TWO MILITARY FORCE STRUCTURE ANALYSIS SIMULATIONS

THE TYCHE AND SAFE MODELS: COMPARING TWO MILITARY FORCE STRUCTURE ANALYSIS SIMULATIONS THE TYCHE AND SAFE MODELS: COMPARING TWO MILITARY FORCE STRUCTURE ANALYSIS SIMULATIONS Cheryl Eiler and Slawomir Weolkowki Daniel T. Wojtazek Centre for Operational Reearch and Analyi Atomic Energy of

More information

4. Amphiphiles. 4.1 Types of amphiphiles. 4.2 Surface activity Surface tension Interface tension

4. Amphiphiles. 4.1 Types of amphiphiles. 4.2 Surface activity Surface tension Interface tension 4. Amhihile 4.1 Tye of amhihile 4.2 Surface activity 4.2.1 Surface tenion 4.2.2 Interface tenion 4.3 Micellization and the critical micelle concentration 4.3.1 Surface tenion and the CMC 4.3.2 Gibb adortion

More information

An economic analysis of a methionine source comparison response model

An economic analysis of a methionine source comparison response model An economic analyi of a methionine ource comparion repone model D. Vedenov and G. M. Peti 1 Department of Agricultural Economic, Texa A&M Univerity, 2124 TAMU, College Station 77843-2124; and Department

More information

requesting information regarding atrial fibrillation in NHS West Kent Clinical Commissioning Group

requesting information regarding atrial fibrillation in NHS West Kent Clinical Commissioning Group NHS Wet Kent Clinical Commiioning Group October 2015 Our Ref: FOI.15.WK0138 requeting information regarding atrial fibrillation in NHS Wet Kent Clinical Commiioning Group Pleae find attached a Freedom

More information

Reading a Textbook Chapter

Reading a Textbook Chapter HENR.546x.APPBpp001-013 7/21/04 9:37 AM Page 1 APPENDIX B Reading a Textbook Chapter Copyright 2005 Pearson Eduation, In. 1 2 Read the following hapter from the ollege textbook Total Fitness: Exerise,

More information

clinical conditions using a tape recorder system

clinical conditions using a tape recorder system Thorax (1964), 19, 125 Objetive assessment of ough suppressants under linial onditions using a tape reorder system C. R. WOOLF AND A. ROSENBERG From the Respiratory Unit, Sunnybrook Hospital (Department

More information

Thi s im. Royal DSM J. Jochems. Economic Diplomacy & Development. Clingendael: 30 August Page 1

Thi s im. Royal DSM J. Jochems. Economic Diplomacy & Development. Clingendael: 30 August Page 1 Royal DSM J. Jochem Economic Diplomacy & Development Clingendael: 30 Augut 2012 Page 1 Thi Who we are: Turnover 2011: 9 billion Workforce: 22,224 R&D: 476 million Page 2 Thi Miion of DSM Our purpoe i to

More information

Model of α-linolenic acid metabolism

Model of α-linolenic acid metabolism Model of α-linoleni aid metabolism N.Kokulan, C.-H. Lai Shool of Computing and Mathematial Sienes University of Greenwih London, UK RAE2012 Competitive Grant with Shool of Siene Projet progress meeting

More information

SIMPLE 3D VASCULARIZATION MODELS FOR PERFUSION BIOREACTORS. Francesco Coletti and Sandro Macchietto 1

SIMPLE 3D VASCULARIZATION MODELS FOR PERFUSION BIOREACTORS. Francesco Coletti and Sandro Macchietto 1 10th International IFAC Sympoium on Computer Appliation Biotehnology Preprt Vol.1, June 4-6, 007, Canún, Mexio SIMPLE 3D VASCULARIZATION MODELS FOR PERFUSION BIOREACTORS Franeo Coletti and Sandro Mahietto

More information

PARKINSON S DISEASE: MODELING THE TREMOR AND OPTIMIZING THE TREATMENT. Keywords: Medical, Optimization, Modelling, Oscillation, Noise characteristics.

PARKINSON S DISEASE: MODELING THE TREMOR AND OPTIMIZING THE TREATMENT. Keywords: Medical, Optimization, Modelling, Oscillation, Noise characteristics. PARKINSON S DISEASE: MODELING THE TREMOR AND OPTIMIZING THE TREATMENT Mohammad Haeri, Yashar Sarbaz and Shahriar Gharibzadeh Advaned Control System Lab, Eletrial Engineering Department, Sharif University

More information

Measurement of Dose Rate Dependence of Radiation Induced Damage to the Current Gain in Bipolar Transistors 1

Measurement of Dose Rate Dependence of Radiation Induced Damage to the Current Gain in Bipolar Transistors 1 Measurement of Dose Rate Dependene of Radiation Indued Damage to the Current Gain in Bipolar Transistors 1 D. Dorfan, T. Dubbs, A. A. Grillo, W. Rowe, H. F.-W. Sadrozinski, A. Seiden, E. Spener, S. Stromberg,

More information

Provide Pain Management theory answer paper Multiple choice

Provide Pain Management theory answer paper Multiple choice Provide Pain Management theory anwer paper Multiple choice You will need to complete a theory paper coniting of four (4) ection with both multiple choice and hort anwer quetion. Section 1 and 2 are compulory.

More information

Supplementary Information Computational Methods

Supplementary Information Computational Methods Supplementary Information Computational Methods Data preproessing In this setion we desribe the preproessing steps taken to establish the data matrix of hepatoyte single ell gene expression data (Table

More information

Distribution of sample means. Estimation

Distribution of sample means. Estimation 1 2 1 1 2 1 2 1 1 2 y y 1 2 1 1 2 y Chater 9 - Iterval Etimatio Sectio 9.4: Iterval Etimatio: Cofidece Iterval for the Poulatio Mea Ditributio of amle mea. Chater 9 - Iterval Etimatio Sectio 9.4: Iterval

More information

Computerized testing of cognitive functions

Computerized testing of cognitive functions Computerized teting of cognitive function PhDr. Jiri Kloe Head of the Central edical Pychology Department Central ilitary Hopital Prague Prague, Czech Republic Doc. PhDr. ilan Brichcin, CSc. Senior Reearch

More information

Chapter 11 Multiway Search Trees

Chapter 11 Multiway Search Trees Chater 11 Multiway Search Trees m-way Search Trees B-Trees B + -Trees C-C Tsai P.1 m-way Search Trees Definition: An m-way search tree is either emty or satisfies the following roerties: The root has at

More information

On Exurban Development *

On Exurban Development * On Exurban Development * David A. NEWBURN a Texa A&M Univerity Peter Berck b Univerity of California Berkeley Abtract In the US, exurbia, the rural area beyond the ewer erved uburb, i being developed with

More information

American Orthodontics Exhibit 1001 Page 1 of 6. US 6,276,930 Bl Aug. 21,2001 /IIIII

American Orthodontics Exhibit 1001 Page 1 of 6. US 6,276,930 Bl Aug. 21,2001 /IIIII (12) United States Patent Pozzi /IIIII 1111111111111111111111111111111111111111111111111111111111111 US006276930Bl (10) Patent No.: (45) Date of Patent: US 6,276,930 Bl Aug. 21,2001 (54) ORTHODONTIC AID

More information

Overview. On the computational aspects of sign language recognition. What is ASL recognition? What makes it hard? Christian Vogler

Overview. On the computational aspects of sign language recognition. What is ASL recognition? What makes it hard? Christian Vogler On the omputational aspets of sign language reognition Christian Vogler Overview Problem statement Basi probabilisti framework Reognition of multiple hannels Reognition features Disussion Gallaudet Researh

More information

A Novel Pulse Compression Scheme Based on Minimum Mean-Square Error Reiteration 1

A Novel Pulse Compression Scheme Based on Minimum Mean-Square Error Reiteration 1 A Novel Pule Compreion Scheme Baed on Minimum Mean-Square Error Reiteration Shannon D. Blunt Karl Gerlach Radar Diviion, Naval Reearch Laboratory 4555 Overlook Ave. S.W. Wahington DC 375 Abtract Thi paper

More information

GRUNDFOS DATA BOOKLET. Hydro Grundfos Hydro 2000 booster sets with 2 to 6 CR(E) pumps 50 Hz

GRUNDFOS DATA BOOKLET. Hydro Grundfos Hydro 2000 booster sets with 2 to 6 CR(E) pumps 50 Hz GRUNDFOS DATA OOKET ydro Grundfos ydro booster sets with 2 to 6 CR(E) ums z Contents Product data Performance range 3 ydro 4 Control 4 Functions 4 Alication and need 5 Water suly 5 Industry 5 Irrigation

More information

NBER WORKING PAPER SERIES THE EFFECTS OF PHARMACEUTICAL MARKETING AND PROMOTION ON ADVERSE DRUG EVENTS AND REGULATION

NBER WORKING PAPER SERIES THE EFFECTS OF PHARMACEUTICAL MARKETING AND PROMOTION ON ADVERSE DRUG EVENTS AND REGULATION NBER WORKING PPER SERIES THE EFFECTS OF PHRMCEUTICL MRKETING ND PROMOTION ON DVERSE DRUG EVENTS ND REGULTION Guy David Sara Markoitz Seth Rihards Working Paer 14634 htt://.nber.org/aers/14634 NTIONL BUREU

More information

Chapter 23 Summary Inferences about Means

Chapter 23 Summary Inferences about Means U i t 6 E x t e d i g I f e r e c e Chapter 23 Summary Iferece about Mea What have we leared? Statitical iferece for mea relie o the ame cocept a for proportio oly the mechaic ad the model have chaged.

More information

CH: Fitness. Physical Fitness- the ability to carry out daily tasks easily and have energy to respond to unexpected demands. Benefits of Exercise..

CH: Fitness. Physical Fitness- the ability to carry out daily tasks easily and have energy to respond to unexpected demands. Benefits of Exercise.. Benefit of Exercie.. CH: Fitne Health ED Phyical Health Nervou Sytem Repiratory Sytem Cardiovacular Sytem Weight control Mental benefit Social benefit Phyical Benefit Emotional Benefit. Lower blood preure

More information

An Interactive Multi-user System for Simultaneous Graph Drawing

An Interactive Multi-user System for Simultaneous Graph Drawing An Inteactive Multi-ue Sytem fo Simultaneou Gah Dawing Stehen G. Kobouov 1 and Chandan Pitta 2 1 Deatment of Comute Science, Univeity of Aizona kobouov@c.aizona.edu 2 Deatment of Electical and Comute Engineeing,

More information

Are piglet prices rational hog price forecasts?

Are piglet prices rational hog price forecasts? AGRICULTURAL ECONOMICS ELSEVIER Agriultural Eonomis 13 (1995) 119-123 Are piglet pries rational hog prie foreasts? Ole GjQ)lberg * Department of Eonomis and Soial Sienes, The Agriultural University of

More information

THE INVESTIGATION OF THE EFFECT OF THE REINFORCEMENT S KIND ON THE TENSILE STRENGTH IN THE FIBER REINFORCED COMPOSITE MATERIALS

THE INVESTIGATION OF THE EFFECT OF THE REINFORCEMENT S KIND ON THE TENSILE STRENGTH IN THE FIBER REINFORCED COMPOSITE MATERIALS Trakia Journal of Science, Vol. 7, Suppl. 2, pp 15-19, 2009 Copyright 2009 Trakia Univerity Available online at: http://www.uni-z.bg ISSN 1313-7050 (print) ISSN 1313-3551 (online) Original Contribution

More information

Contour Integration in Anisometropic Amblyopia

Contour Integration in Anisometropic Amblyopia Pergamon PII: 0042-6989(97)00233-2 Viion Re., Vol. 38, No. 6, pp. 889-894, 1998 1998 Elevier cience Ltd. All right reerved Printed in Great Britain 0042-6989/98 $19.00 + 0.00 Contour Integration in Aniometropic

More information

CRIKEY - A Temporal Planner Looking at the Integration of Scheduling and Planning

CRIKEY - A Temporal Planner Looking at the Integration of Scheduling and Planning CRIKEY - A Temoral Planner Looking at the Integration of Scheduling and Planning Keith Halsey and Derek Long and Maria Fox University of Strathclyde Glasgow, UK keith.halsey@cis.strath.ac.uk Abstract For

More information

Seismic Response Control of Structures using Liquid Column Vibration Absorber Considering Real Earthquake Ground Motions

Seismic Response Control of Structures using Liquid Column Vibration Absorber Considering Real Earthquake Ground Motions Seimic Repone Control of Structure uing iquid Column Vibration Aborber Conidering Real Ground Motion Debai Panda M. Tech Scholar National Intitute of Technology Agartala Agartala, India Dr. Rama Debbarma

More information

Systematic Review of Trends in Fish Tissue Mercury Concentrations

Systematic Review of Trends in Fish Tissue Mercury Concentrations Systemati Review of Trends in Fish Tissue Merury Conentrations Tom Grieb 1, Roxanne Karimi 2, Niholas Fisher 2, Leonard Levin 3 (1) Tetra Teh, In., Lafayette, CA, USA; (2) State University of New York,

More information

Intro to Scientific Analysis (BIO 100) THE t-test. Plant Height (m)

Intro to Scientific Analysis (BIO 100) THE t-test. Plant Height (m) THE t-test Let Start With a Example Whe coductig experimet, we would like to kow whether a experimetal treatmet had a effect o ome variable. A a imple but itructive example, uppoe we wat to kow whether

More information

Joint Dictionary Learning-based Non-Negative Matrix Factorization for Voice Conversion to Improve Speech Intelligibility After Oral Surgery

Joint Dictionary Learning-based Non-Negative Matrix Factorization for Voice Conversion to Improve Speech Intelligibility After Oral Surgery > RPLAC HS LN WH YOUR PAPR DNFCAON NUMBR (DOUBL-CLCK HR O D) < oint Dictionary Learning-baed Non-Negative Matrix Factorization for Voice Converion to mprove Speech ntelligibility After Oral Surgery Szu-Wei

More information

Detection and Classification of Brain Tumor in MRI Images

Detection and Classification of Brain Tumor in MRI Images PrahiGadpayle and Prof.P.S.Mahajani 45 Detetion and Classifiation of Brain Tumor in MRI Images PrahiGadpayleand Prof.P.S.Mahajani Abstrat Brain tumor detetion in Magneti Resonane Imaging (MRI) is important

More information

REVIEW for Exam 2. Chapters 9 13 (& chi-square in ch8)

REVIEW for Exam 2. Chapters 9 13 (& chi-square in ch8) REVIEW for Exam Chapter 9 3 & chi-quare in ch8 True or Fale. Etimated tandard error of the mean in a paired-ample t-tet i baed on the variance of the difference core.. W/in S deign i particularly ueful

More information

Discover how Septodont RTR starts the bone growth process and helps nature finish it! Order Information: Some lead... others follow.

Discover how Septodont RTR starts the bone growth process and helps nature finish it! Order Information: Some lead... others follow. RTR Sellheet www.eptodontua.com 0.8 cc of ß tricalcium phophate granule (diameter 0.5 to 1mm) in terile yringe (individually packaged). call Septodont at...and help nature finih it! RTR (Reorbable Tiue

More information

Predicting Peptides That Bind to MHC Molecules Using Supervised Learning of Hidden Markov Models

Predicting Peptides That Bind to MHC Molecules Using Supervised Learning of Hidden Markov Models PROTEINS: Structure, Function, and Genetic 33:460 474 (1998) RESEARCH ARTICLES Predicting Peptide That Bind to MHC Molecule Uing Supervied Learning of Hidden Markov Model Hirohi Mamituka* C&C Media Reearch

More information

Every Flex is Quite Complex

Every Flex is Quite Complex Name Class Date Every Flex is Quite Complex Struture and Funtion in a Chiken Wing Investigative Lab 27 8 Question How do the tissues of a hiken wing work together during movement? Lab Overview In this

More information

RIV-TI Internuts blind rivet nuts

RIV-TI Internuts blind rivet nuts light duty teel and aluminium round, hex and knurled bodie flat, counterunk and lim head Fatening Technology RIV-TI Internut Internut TUK(0605)1 RIV-TI Internut Round Flat Open End aluminium teel 4 4 Counterunk

More information

Study on damage evolution characteristics of coal and rock uniaxial compression based on the acoustic emission

Study on damage evolution characteristics of coal and rock uniaxial compression based on the acoustic emission 4th Internationa onferene on Sutainae Energy and Environmenta Engineering (ISEEE 2015) Study on damage evoution harateriti of oa and rok uniaxia omreion aed on the aouti emiion Shugang Li1, a, Ning Wang1,,

More information

Evaluation of a Program to Enhance Young Drivers Safety in Israel

Evaluation of a Program to Enhance Young Drivers Safety in Israel Evaluation of a Program to Enhance Young Driver Safety in Irael Tomer Toledo* Technion Irael Intitute of Technology, Haifa, Irael Tippy Lotan Or Yarok, Hod Haharon, Irael Orit Taubman - Ben-Ari Bar-Ilan

More information

Study of Fixed Assets Investment s Effect on the Employment of Three Industries

Study of Fixed Assets Investment s Effect on the Employment of Three Industries Proceeding of the 7th International Conference on Innovation & Management 951 Study of Fixed Aet Invetment Effect on the Employment of Three Indutrie Fan Fan, Li Jing Intitute of Economic, Yangtze Univerity,

More information

This is an author-deposited version published in: Eprints ID: 15989

This is an author-deposited version published in:   Eprints ID: 15989 Oen Archive TOULOUSE Archive Ouverte (OATAO) OATAO is an oen access reository that collects the work of Toulouse researchers and makes it freely available over the web where ossible. This is an author-deosited

More information

Lipid Segregation on Cylindrically and Spherically Curved Membranes

Lipid Segregation on Cylindrically and Spherically Curved Membranes Lipid Segregation on Cylindrically and Spherically Curved Membrane where n and u are unit vector repreenting, repectively, lipid orientation and membrane normal, repreent the two-dimenional derivative

More information

Methio - by. Ruminants. Nutrition. Health. Line. was established in s. s y. Program. Program

Methio - by. Ruminants. Nutrition. Health. Line. was established in s. s y. Program. Program Line Ruminant Program Program Health N Nutrition H The production area i about 30,000 quare metre. The production capacity i 120,000 ton of Monoglyceride per year. SILO i the leader in the development

More information

describing DNA reassociation* (renaturation/nucleation inhibition/single strand ends)

describing DNA reassociation* (renaturation/nucleation inhibition/single strand ends) Pro. Nat. Aad. Si. USA Vol. 73, No. 2, pp. 415-419, February 1976 Biohemistry Studies on nulei aid reassoiation kinetis: Empirial equations desribing DNA reassoiation* (renaturation/nuleation inhibition/single

More information

STAT 200. Guided Exercise 7

STAT 200. Guided Exercise 7 STAT 00 Guided Exercise 7 1. There are two main retirement lans for emloyees, Tax Sheltered Annuity (TSA) and a 401(K). A study in North Carolina investigated whether emloyees with similar incomes differ

More information

Shift work is a risk factor for increased total cholesterol level: a 14-year prospective cohort study in 6886 male workers

Shift work is a risk factor for increased total cholesterol level: a 14-year prospective cohort study in 6886 male workers Original artile 1 Department of Oupational and Environmental Mediine, Graduate Shool of Mediine, Chiba University, Chiba, Japan; 2 Center for Preventive Medial Siene, Chiba University, Chiba, Japan; 3

More information

Identification and low-complexity regime-switching insulin control of type I diabetic patients

Identification and low-complexity regime-switching insulin control of type I diabetic patients J. Biomedical cience and Engineering,, 4, 97-34 doi:.436/jbise..444 Published Online Aril (htt://www.cirp.org/journal/jbise/). Identification and low-comlexity regime-switching insulin control of tye I

More information

Spinal Flexibility and Individual Factors That Influence It

Spinal Flexibility and Individual Factors That Influence It Spinal lexibility and Individual actor That Influence It ICHELE C. BATTI'E, STANLEY J. BIGOS, ANN SHEEHY, and ARK D. WORTLEY We conducted an invetigation to examine the pinal flexibility of a large, adult

More information

Evaluating the effectiveness of rating instruments for a communication skills assessment of medical residents

Evaluating the effectiveness of rating instruments for a communication skills assessment of medical residents Adv in Health Sci Educ (2009) 14:575 594 DOI 10.1007/10459-008-9142-2 ORIGINAL PAPER Evaluating the effectivene of rating intrument for a communication kill aement of medical reident Cherdak Iramaneerat

More information

Objectives. 6.3, 6.4 Quantifying the quality of hypothesis tests. Type I and II errors. Power of a test. Cautions about significance tests

Objectives. 6.3, 6.4 Quantifying the quality of hypothesis tests. Type I and II errors. Power of a test. Cautions about significance tests Objectives 6.3, 6.4 Quantifying the quality of hyothesis tests Tye I and II errors Power of a test Cautions about significance tests Further reading: htt://onlinestatbook.com/2/ower/contents.html Toics:

More information

Cognitive Modeling & Processing for Speech Recognition Ears and Beyond

Cognitive Modeling & Processing for Speech Recognition Ears and Beyond Introduction Cognitive Modeling & Proceing for Speech Recognition Ear and Beyond B.H. Juang & Woojay Jeon Georgia Intitute of Technology February, 5 ASR ytem till perform far wore than human litener under

More information

NEPHROCHECK Calibration Verification Kit Package Insert

NEPHROCHECK Calibration Verification Kit Package Insert NEPHROCHECK Verifiation Kit Pakage Insert Manufatured for Astute Medial, In. 3550 General Atomis Ct. Building 2 San Diego, CA 92121 USA Intended Use The NEPHROCHECK Verifiation (Cal Vers) Materials are

More information

is the branch of science that studies the transformation of energy from one form to another. Thermochemistry specifically studies.

is the branch of science that studies the transformation of energy from one form to another. Thermochemistry specifically studies. is the branh of siene that studies the transforation of energy fro one for to another. Theroheistry speifially studies. I. Energy and Its Fors A. Energy Defined B. Two Fors of Energy Energy ( ) Energy

More information

The effects of bilingualism on stuttering during late childhood

The effects of bilingualism on stuttering during late childhood Additional information is published online only at http:// ad.bmj.om/ontent/vol93/ issue11 1 Division of Psyhology and Language Sienes, University College London, London, UK; 2 Department of Language and

More information

International Journal of Scientific Research and Reviews

International Journal of Scientific Research and Reviews Reearch article Available online www.ijrr.org ISSN: 2279 0543 International Journal of Scientific Reearch and Review Performance Meaure of The Homeopathic Medication In Curing The Thyroid Hormone Diorder

More information

Mark J Monaghan. Imaging techniques ROLE OF REAL TIME 3D ECHOCARDIOGRAPHY IN EVALUATING THE LEFT VENTRICLE TIME 3D ECHO TECHNOLOGY

Mark J Monaghan. Imaging techniques ROLE OF REAL TIME 3D ECHOCARDIOGRAPHY IN EVALUATING THE LEFT VENTRICLE TIME 3D ECHO TECHNOLOGY Take the online multiple hoie questions assoiated with this artile (see page 130) Correspondene to: Dr Mark J Monaghan, Department of Cardiology, King s College Hospital, Denmark Hill, London SE5 9RS,

More information

Channel Modeling Based on Interference Temperature in Underlay Cognitive Wireless Networks

Channel Modeling Based on Interference Temperature in Underlay Cognitive Wireless Networks Channel Modeling Based on Interferene emperature in Underlay Cognitive Wireless Networks Manuj Sharma # *, Anirudha Sahoo #2, K. D. Nayak * # Dept. of Computer Siene & Engineering Indian Institute of ehnology

More information

On The Use of Coefficient of Variation and 1, 2

On The Use of Coefficient of Variation and 1, 2 Samlg Stratege for Fte Poulato Ug Auxlary Iformato O e Ue of oeffet of arato ad, Etmatg Mea of a Fte Poulato B. B. Kare, P. S. Ja ad U. Srvatava Deartmet of Statt, B.H.U, araa-005 Statt Seto, MM, B.H.U,

More information

Formative design and evaluation of patient-delivered partner therapy informational materials and packaging

Formative design and evaluation of patient-delivered partner therapy informational materials and packaging See Editorial, p 80 Additional information is published online only at http:// sti.bmj.om/ontent/vol85/ issue2 1 Indiana University Shool of Mediine, Indianapolis, Indiana, USA; 2 Aademi Edge, In, Bloomington,

More information

Chemically bound water as measure of degree of hydration: method and potential errors

Chemically bound water as measure of degree of hydration: method and potential errors Chemially bound ater as measure of degree of hydration: method and potential errors Fagerlund, Göran Published: 29-1-1 Link to publiation Citation for published version (APA): Fagerlund, G. (29). Chemially

More information

Chapter 7 - Hypothesis Tests Applied to Means

Chapter 7 - Hypothesis Tests Applied to Means Chapter 7 - Hypothei Tet Applied to Mea 7.1 Ditributio of 100 radom umber: mea(dv) = 4.46 t. dev(dv) =.687 var(dv) = 7. 7.3 Doe the Cetral Limit Theorem work? The mea ad tadard deviatio of the ample are

More information

QUANTITATIVE STUDIES ON THE CILIATE GLAUCOMA

QUANTITATIVE STUDIES ON THE CILIATE GLAUCOMA 422 QUANTITATIVE STUDIES ON THE CILIATE GLAUCOMA I. THE REGULATION OF THE SIZE AND THE FISSION RATE BY THE BACTERIAL FOOD SUPPLY BY J. P. HARDING, PH.D. Zoological Laboratory, Cambridge (Received 2 February

More information

Crossmodal temporal discrimination: Assessing the predictions of a general pacemaker counter model

Crossmodal temporal discrimination: Assessing the predictions of a general pacemaker counter model Journal Perception & Pychophyic 6,?? 68 (?), (7),???-??? 114-115 Cromodal temporal dicrimination: Aeing the prediction of a general pacemaker counter model ROLF ULRICH and JUDITH NITSCHKE Univerity of

More information

Chapter 4: One Compartment Open Model: Intravenous Bolus Administration

Chapter 4: One Compartment Open Model: Intravenous Bolus Administration Home Readings Search AccessPharmacy Adv. Search Alied Bioharmaceutics & Pharmacokinetics, 7e > Chater 4 Chater 4: One Comartment Oen Model: Intravenous Bolus Administration avid S.H. Lee CHAPTER OBJECTIVES

More information

Confidence Intervals and Point Estimation

Confidence Intervals and Point Estimation Cofidece Iterval ad Poit Etimatio x ε < µ < x + ε ε = z σ x ε < µ < x + ε ε = t ν,, ν = 1 = z σ ε ˆp ε < p < ˆp + ε ε = z ˆp ˆq = z ε pq ( 1) < σ < ( 1), ν = 1 χ ν, χ ν, 1 ( x 1 x ) ε < µ 1 µ < ( x 1 x

More information

Monte Carlo dynamics study of motions in &s-unsaturated hydrocarbon chains

Monte Carlo dynamics study of motions in &s-unsaturated hydrocarbon chains Monte Carlo dynamis study of motions in &s-unsaturated hydroarbon hains Y. K. Levine Department of Moleular Biophysis, Buys Ballot Laboratory, The Netherlands University of Utreht, 3508 TA Utreht, A. Kolinski

More information

MUSCULAR DISTRIBUTION OF TRICHINELLA spiralis LARVAE IN PORK FRESH MEET

MUSCULAR DISTRIBUTION OF TRICHINELLA spiralis LARVAE IN PORK FRESH MEET MUSCULAR DISTRIBUTION OF TRICHINELLA pirali LARVAE IN PORK FRESH MEET Eugeniu AVRAM x, Daniela ROB RACOLŢA xx Vaile SECARĂ xxx Univeritatea de Vet Vaile Goldiş Arad, Engineering Faculty x, tudent at Natural

More information

Cost utility analysis of chemotherapy in symptomatic advanced nonsmall cell lung cancer

Cost utility analysis of chemotherapy in symptomatic advanced nonsmall cell lung cancer Eur Repir J 2006; 27: 895 901 DOI: 10.1183/09031936.06.00102705 CopyrightßERS Journal Ltd 2006 Cot utility analyi of chemotherapy in ymptomatic advanced nonmall cell lung cancer C.A. Doom*, Y.N. Lieven

More information

ACOG COMMITTEE OPINION

ACOG COMMITTEE OPINION INTERIM UPDATE ACOG COMMITTEE OPINION Number 757 (Replaes Committee Opinion No. 630, May 2015) Committee on Obstetri Pratie This Committee Opinion was developed by the and Gyneologists Committee on Obstetri

More information

Historically, occupational epidemiology studies have often been initiated in response to concerns

Historically, occupational epidemiology studies have often been initiated in response to concerns Eduation SELECTING APPROPRIATE STUDY DESIGNS TO ADDRESS SPECIFIC RESEARCH QUESTIONS IN OCCUPATIONAL EPIDEMIOLOGY Harvey Chekoway, Neil Peare, David Kriebel 633 Oup Environ Med 2007; 64:633 638. doi: 10.1136/oem.2006.029967

More information

Costly Price Discrimination

Costly Price Discrimination Costly Prie Disrimination Peter T. Leeson and Russell S. Sobel Department of Eonomis, West Virginia University February 16, 26 Abstrat In standard miroeonomi theory, perfet prie disrimination is soially

More information

The burden of smoking-related ill health in the United Kingdom

The burden of smoking-related ill health in the United Kingdom The burden of smoking-related ill health in the United Kingdom S Allender, R Balakrishnan, P Sarborough, P Webster, M Rayner Researh paper Department of Publi Health, University of Oxford, Oxford, UK Correspondene

More information

www.aademijournals.om Asian Journal of Animal and Veterinary Advanes 0 (4): 79-84, 05 ISSN 68-999 / DOI: 0.9/ajava.05.79.84 05 Aademi Journals In. Effet of Supplementation of Fiber Degrading Enzymes on

More information

An FSIS Update on the Prevention and Control of Foodborne Salmonella

An FSIS Update on the Prevention and Control of Foodborne Salmonella 1 Outline An FSIS Update on the Prevention and Control of Foodborne Salmonella Karen Becker, DVM, MPH, DACVPM Director, Applied USDA/ USAHA Salmonella Committee Providence, RI Oct 27, 2015 2 FSIS Miion

More information

A DESIGN ASSESSMENT TOOL FOR SQUEAK AND RATTLE PERFORMANCE

A DESIGN ASSESSMENT TOOL FOR SQUEAK AND RATTLE PERFORMANCE A DESIGN ASSESSMENT TOOL FOR SQUEAK AND RATTLE PERFORMANCE David E. Soine, Harold A. Evensen, and Charles D. Van Karsen Center for Applied Researh in Dynai Systes Mehanial Engineering-Engineering Mehanis

More information

Multinational Knowledge Spillovers with Centralized versus Decentralized R&D: a game theoretic approach

Multinational Knowledge Spillovers with Centralized versus Decentralized R&D: a game theoretic approach Mutinationa Knowege Siover with Centraize veru Deentraize R&D: a gae theoreti aroah By FRANCESCA SANNA-RANDACCIO Univerity of Roe La Saienza Via Buonarroti 1 00185 Roe, Itay E-ai: fr@i.uniroa1.it Te: 39-06-48998

More information

Lecture 18b: Practice problems for Two-Sample Hypothesis Test of Means

Lecture 18b: Practice problems for Two-Sample Hypothesis Test of Means Statitic 8b_practice.pdf Michael Halltoe, Ph.D. hallto@hawaii.edu Lecture 8b: Practice problem for Two-Sample Hypothei Tet of Mea Practice Everythig that appear i thee lecture ote i fair game for the tet.

More information

Effects of training to implement new working methods to reduce knee strain in floor layers. A twoyear

Effects of training to implement new working methods to reduce knee strain in floor layers. A twoyear Department of Oupational Mediine, Region Hospital Skive, Denmark Correspondene to: Dr L K Jensen, Department of Oupational Mediine, Region Hospital Skive, Resenvej 25, DK- 7800 Skive, Denmark; lilli.kirkeskov.jensen@

More information

Rate of processing and judgment of response speed: Comparing the effects of alcohol and practice

Rate of processing and judgment of response speed: Comparing the effects of alcohol and practice Pereption & Psyhophysis 1989, 45 (4), 431-438 Rate of proessing and judgment of response speed: Comparing the effets of alohol and pratie E. A. MAYLOR, P. M. A. RABBITT, and S. A. V. CONNOLLY University

More information

What causes the spacing effect? Some effects ofrepetition, duration, and spacing on memory for pictures

What causes the spacing effect? Some effects ofrepetition, duration, and spacing on memory for pictures Memory & Cognition 1975, Vol. 3 (3), 287 294 What auses the spaing effet? Some effets ofrepetition, duration, and spaing on memory for pitures DOUGLAS 1. HNTZMAN, JEFFERY J. SUMMERS, and RCHARD A. BLOCK

More information

Interrelationships of Chloride, Bicarbonate, Sodium, and Hydrogen Transport in the Human Ileum

Interrelationships of Chloride, Bicarbonate, Sodium, and Hydrogen Transport in the Human Ileum Interrelationships of Chloride, Biarbonate, Sodium, and Hydrogen Transport in the Human Ileum LEsLE A. TURNBERG, FREDERICK A. BIEBERDORF, STEPHEN G. MORAWSKI, and JOHN S. FORDTRAN From the Department of

More information

RADIATION DOSIMETRY INTRODUCTION NEW MODALITIES

RADIATION DOSIMETRY INTRODUCTION NEW MODALITIES RADIATION DOSIMETRY M. Ragheb 1/17/2006 INTRODUCTION Radiation dosimetry depends on the aumulated knowledge in nulear siene in general and in nulear and radio hemistry in partiular. The latter is onerned

More information

(12) United States Patent (10) Patent No.: US 9,011,147 B2

(12) United States Patent (10) Patent No.: US 9,011,147 B2 US00901 1147B2 (12) United State Patent () Patent No.: US 9,011,147 B2 Jacquemyn (45) Date of Patent: Apr. 21, 20 (54) DENTIST TOOL 4,144,645 A * 3/1979 Marhall... 433,223 4,504.230 A 3, 1985 Patch (75)

More information

Appendix A: Clinical question and search strategies

Appendix A: Clinical question and search strategies APPENDICES Appendix A: Clinical quetion and earch trategie Study type Quetion ID Quetion wording filter ued Databae and year PHAR2a What i the afety and efficacy of apirin veru Sytematic review, Medline

More information

Firms cash holdings and uncertainty

Firms cash holdings and uncertainty Firm cah holding and uncertainty Ruoran Gao Yaniv Grintein Thi verion: 5/13/2013 Preliminary Pleae do not quote without permiion Abtract We examine the dynamic relation between uncertainty and cah holding

More information

The impact of smoking and quitting on household expenditure patterns and medical care costs in China

The impact of smoking and quitting on household expenditure patterns and medical care costs in China Researh paper Appendies are published online only at http:// tobaoontrol.bmj.om/ ontent/vol18/issue2 1 Center for Health Statistis and Information, Ministry of Health, Beijing, PR China; 2 International

More information

The effects of question order and response-choice on self-rated health status in the English Longitudinal Study of Ageing (ELSA)

The effects of question order and response-choice on self-rated health status in the English Longitudinal Study of Ageing (ELSA) The effets of question order and response-hoie on self-rated health status in the English Longitudinal Study of Ageing (ELSA) A Bowling, J Windsor Theory and methods Department of Primary Care and Population

More information

Graph theory in veterinary epidemiology - modelling an outbreak of classical swine fever

Graph theory in veterinary epidemiology - modelling an outbreak of classical swine fever Grah theory in veterinary eidemiology - modelling an outbreak o claical wine ever Stean Widgren Handledare: Ivar Vågholm Int. ör idilarmedicin och eidemiologi. Bitr.handledare: Marie Engel Int. ör idilarmedicin

More information

4th. generally by. Since most. to the. Borjkhani 1,* Mehdi. execution [2]. cortex, computerized. tomography. of Technology.

4th. generally by. Since most. to the. Borjkhani 1,* Mehdi. execution [2]. cortex, computerized. tomography. of Technology. 4th Internatiional Conferene of Fuzzy Information & Engineering 14 15 Otober 0100 Shomal University, Amol, Iran Diagnosiss of Parkinson diseases based on handwriting kinematis using fuzzy lassifier Mehdi

More information