EDUCATION: Bachelor of Science in Biology, Pittsburg State University, Pittsburg Kansas

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1 CURRICULUM VITAE JENNIFER SIMPSON, M.D. Assistant Professor of Neurology East Seventeenth Avenue, Mail Stop L950 Aurora, CO (Fax) EDUCATION: Bachelor of Science in Biology, Pittsburg State University, Pittsburg Kansas M.D., University of Kansas School of Medicine, Kansas City, Kansas Resident of Internal Medicine, St. Joseph Mercy Hospital, Ann Arbor, Michigan Resident in Neurology, University of Michigan Hospital, Ann Arbor Michigan Chief Resident of Neurology, University of Michigan Hospital, Ann Arbor Michigan Vascular Neurology Fellow, Henry Ford Hospital, Detroit Michigan ACADEMIC APPOINTMENTS: 2011 Present University of Colorado Denver, Anschutz Medical Campus, Assistant Professor of Neurology and Internal Medicine HOSPITAL, GOVERNMENT OR OTHER PROFESSIONAL POSITIONS: 2014 Present Clinical Instructor, Skaggs School of Pharmacy and Pharmaceutical Sciences HONORS, SPECIAL RECOGNITIONS AND AWARDS: 2012 Univerity of Colorado Neurology Residents Faculty Teaching Award 2013 Univeristy of Colorado Medical Staff Award, Pioneer Award 2013 Faculty Student Teaching Award 2014 Peak Performer Award MEMBERSHIP IN PROFESSIONAL ORGANIZATIONS 2007 Present Member, American Academy of Neurology 2011 Present Member. American Heart Association 2011 Present Member, Children s Hospital of Colorado Acute Stroke Team 2012 Present American Neurological Association Member, American Society of Neuroimaging MAJOR COMMITTEE AND SERVICE RESPONSIBILITIES: 2012 University of Colorado Denver, Director of the Vascular Block of the Neurology Resident Seminars 2012 Present American Heart Association Early Career Committee member

2 Jennifer Simpson, MD, Curriculum Vitae, Page University of Colorado Denver, Director of the Neurological Emergencies Block of the Neurology Resident Seminars 2014 Present Director of Quality Improvement, Department of Neurology 2014 Present Chair, Neurology Performance Improvement Committee 2014 Present Board Member, Maintenance of Certification Program, University of Colorado School of Medicine 2015 Present Co-Chair, Neuroscience Quality Improvement Committee 2016 Present Clinical Effectiveness and Patient Safety Small Grants Program Committee Member, University of Colorado Hospital 2016 Present Member, Peer to Peer Network, University of Colorado Hospital LICENSURE AND BOARD CERTIFICATION: 2010 Diplomate, American Board of Psychiatry and Neurology State of Michigan Permanent License ( ), Present State of Colorado Permanent License (50090) 2011 Diplomate, American Board of Psychiatry and Neurology, Vascular Neurology Certification, Americal Society of Neuroimaging, Comprehensive Neurosonology REVIEW AND REFEREE WORK: 2010 Ad hoc reviewer, Stroke, A Journal of the American Heart Association 2010 Ad hoc reviewer, Neurology 2010 Ad hoc reviewer, Canadian Journal of Neurological Sciences 2011 Ad hoc reviewer, Journal of Neurological Sciences 2011 Ad hoc reviewer, Neuroepidemiology 2012 Present Reviewer, Neurohospitalist 2013 Present Associate Editor, Images Section, The Neurohospitalist INVITED EXTRAMURAL LECTURES, PRESENTATIONS AND VISITING PROFESSORSHIPS: Local/Regional: Intravenous thrombolysis and quality measures. Platte Valley Medical Center, invited speaker. Brighton, CO. August Using the Neuro Exam to Diagnose Mimics. University of Colorado, Internal Medicine Grand Rounds. Aurora, CO. September 2012 Acute Stroke Diagnosis and Management, What Now: Risk Stratification & Medical Management After Stroke & TIA, and Using the Neuro Exam to Diagnose Mimics. Rocky Mountain Hospital Medicine Symposium, invited speaker. Denver, CO. September Development of a Multidisciplinary Transient Ischemic Attack (TIA) Clinic at the University of Colorado Hospital." Rocky Mountain Hospital Medicine Symposium. Aurora, CO. August Saving Neurons Night and Day: Improving Acute Stroke Care. Hospitalist QI Summit. Auora, CO. January 2014 Acute Ischemic Stroke: What Every EMT Needs to Know Colorado State EMS Conference. Keystone, CO. November 2014 Stroke Diagnostics. American Association of Neurosciences Nurses Stroke Certification Review Course. Aurora, CO. March Keeping Your Interior Highway in Top Condition. Let s Talk, Conversations about Women s Health, University of Colorado Hospital. Aurora, CO. March 2015.

3 Jennifer Simpson, MD, Curriculum Vitae, Page 3 Keeping Your Interior Highway in Top Condition. Let s Talk, Conversations about Women s Health, University of Colorado Hospital. Aurora, CO. February Breaking Down TIA: Who, What, Where. 52 nd Annual Internal Medicine Program, Estes Park, CO. July 22, 2016 University of Colorado Department of Neurology Grand Rounds: o Transient Ischemic Attack, April 2011 o Controversial Inpatient Issues in Neurology, March 2013 o Just Do It. July 2014 o QI Project: Improving Patient Education About Medications Started in the Hospital Setting. Februrary 2014 o Quality Case Reviews, Morbidity and Mortality Series, August 2014, October 2014, February 2015, August 2015, November 2015, January 2016, August 2016 National: Mexican Americans with Atrial Fibrillation and Stroke have a Higher Risk of Recurrent Stroke than Non-Hispanic Whites. American Neurological Association Special Interest Group. New Orleans, LA. October Success Story: Improving Time of Hospital Discharge with Quality Improvement Methods. Association of University Professors of Neurology 2013 Leaders Forum. New Orleans, LA. October Patient Satisfaction: Use Data to Improve Care. Neurohospitalist Society Annual Meeting. Atlanta, GA. October Things We Do For No Reason. Neurohosptialist Society Annual Meeting. Salt Lake City, UT, September TEACHING RECORD: Medical Student: April 2013 EMED 8007 Critical Care and Procedures, curriculum development, Altered Mental Status May 2015 Medical Errors Disclosure Phase III Small Group Session, training for third year medical students. September 2015 Ischemic Stroke. Nervous System Unit 2, MS2 Course Presentations to House Officers August 2011 Stroke Epidemiology. February 2012 Stroke Simulation, Wells Simulation Center February 2012 Uncommon Causes of Stroke July 2012 Ischemic Stroke, Emergency Lecture Series August 2012 Stroke Simulation, Wells Simulation Center April 2013 Hospital Medicine Fellowship Seminar Series, Ischemic Stroke Neurology Resident Emergency Block Director, July 2013 Stroke Simulation, Wells Simulation Center October 2013 Mentor, The Basal Ganglia, with Jason Fleming February 2014 Neuroradiology RITE Review, Rite Review Block. July 2014 & 2015 Neurological Emergencies Simulations July 2016 Vertigo, the Good, the Bad, and the Really Bad Presentations to Other Medical Staff 2013 Present NIH Stroke Scale Classes to UCH Nurses November 2013 Presentation to UCH EMT s, Stroke

4 February 2014 Jennifer Simpson, MD, Curriculum Vitae, Page 4 Preparation for the Stroke Certified Registered Nurse Exam: Hyperacute Care of the Stroke Patient Community Events Feb 2014 & 2015 Leadership Aurora, Advanced Stroke Care at the University of Colorado Hospital. Preceptorships/Mentorships 2012 Colorado Rural Health Scholars Preceptor 2012 Present MD preceptor, University of Colorado School of Pharmacy and Pharmaceutical Sciences Lisa Hong, 2012 Kristen Swadley, 2013 Lida Bigash, 2014 Arshdeep Dhillon, Faculty Mentor, Darcy O Banion, MS, RN, ACCNS-AG, CNRN, SCRN, Clinical Nurse Scientist Program, University of Colorado 2016 Faculty Mentor, Michelle Rove, Master of Public Health Practicum, Colorado School of Public Health Medical Student Mentorship Faculty Mentored Scholarly Activity, Matt Grant 2013 Young Hospitalist Academy, Stephen Groves, MBA, David Medrano, Catherine Musselman, Melanie Muszelik, Raquel de Andrade Pereira, Megan Ross, MPH, Madeline Rovira, Stephanie Voss Quality improvement initiative, Raquel De Andrade Pereira Neurology Resident/Fellow Mentorship Career guidance, David Case, MD, Vascular Neurology Fellow Research and career mentorship, Angel Pulido, MD, Neurology Resident and Vascular Neurology Fellow Faculty Mentor, Andreas Michas-Martin, MD, Neurology Resident Quality improvement and career mentorship, Charles Braun, MD, Neurology Resident Research and career mentorship, Andreas Michas-Martin, MD, Neurology Resident 2013-present Research and career mentorship, Michelle Leppert, MD, MBA, Neurology Resident 2015-present Faculty Mentor, Sasan Salimian, MD, Neurology Resident Ward/Clinic Attending Duties 2011-present Neurology clinic, University of Colorado Hospital. Supervise medical students and vascular neurology fellows in the stroke and neurohospitalist clinics present Inpatient Neurology Service, University of Colorado Hospital. Supervise medical students, neurology and psychiatry residents for weeks a year present Inpatient Stroke Service, University of Colorado Hospital. Supervise medical students, neurology and neurosurgery residents, and vascular neurology fellows for weeks per year. GRANT SUPPORT: NINDS POINT Platelet-Oriented Inhibition in New TIA Platelet-Oriented Inhibition in New TIA (POINT) Trial. 9/1/2011-8/31/2017

5 Role: Site Principal Investigator Direct Costs: $37,000 Indirect Costs: $13,000 Total Costs: $50,000 Jennifer Simpson, MD, Curriculum Vitae, Page 5 Wells Center Simulation Training Granted Hours Description: Four quarterly four hour events and two in-situ events (three hours each) to look at inter-professional training and process/safety issues in neurology residents. The training has standardized patients with neurological disorders, and patients are recruited to be standardized patients. Completed: University of Colorado Clinical Effectiveness and Patient Safety Small Grants Program: Transient Ischemic Attack Clinic, Role: Principal Investigator Total Costs: $25,000 Description: This is a small grant for quality improvement research in which we developed a clinic to see patients with transient ischemic attack in the outpatient setting. The goal was to streamline the outpatient workup of this condition to prevent a hospital admission. We collected data on patient satisfaction and incidence of stroke following TIA. OTHER RESEARCH ENDEAVORS: Patent Foramen Ovale and Atrial Septal Defect Closure Outcomes Role: PI MicroRNA Analysis of Patients with Ischemic Stroke and Healthy Control Subjects Role: PI Phase II, Randomized, Double-Blind, Placebo-Controlled Trial of Extended-Release Niacin to Augment Recovery after Subacute Stroke POINT, Platelet-oriented Inhibition in New TIA and Minor Ischemic Stroke Trial (NINDS) Intra-Arterial Therapy in Acute Stroke Role: PI CHOICE, Carotid Stenting For High Surgical-Risk Patients; 2011 Evaluating Outcomes through the Collection of Clinical Evidence RESPECT PFO Clinical Trial Role: Co-I

6 Jennifer Simpson, MD, Curriculum Vitae, Page 6 Insulin Resistance Intervention after Stroke or TIA Role-Co-I TIPS, Thrombolysis in Pediatric Stroke; Children s Hospital of Colorado Role: Sub-CO-I ICTUS, Intravascular Cooling in the Treatment of Stroke Trial PARTNERS II, Placement of AoRTic TraNscathetER Valves REDUCE, Gore Helex Septal Occluder for Patent Foramen Ovale Closure in Stroke Patients CREST-2, Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial, neurology lead 2012-present 2014-present 2015-present BIBLIOGRAPHY: Peer-Reviewed Publication: 1. Simpson JR, Zahuranec DB, Lisabeth LD, Sanchez BN, Skolarus LE, Mendizabal JE, Smith MA, Garcia NM, Morgenstern, LB. Mexican Americans With Atrial Fibrillation Have More Recurrent Strokes Than Do Non-Hispanic Whites. Stroke. 2010;41(10): Miller DJ, Khan MA, Schultz LR, Simpson JR, Katramados AM, Russman AN, Mitsias PD. Outpatient cardiac telemetry detects a high rate of atrial fibrillation in cryptogenic stroke. J Neurol Sci Jan 15;324(1-2): Miller DJ, Simpson JR, Silver B. Safety of thrombolysis in Acute Ischemic Stroke: A Review of Complications, Risk Factors, and Newer Technologies. Neurohospitalist. 2011; 1(3): Simpson JR, Cumbler EU, Rosenthal LD, Likosky DJ. Inpatient Falls: Defining the Problem and Identifying Possible Solutions. Part I: An Evidence Based Review. The Neurohospitalist. Published online 5 February Cumbler EU, Simpson JR, Rosenthal LD, Likosky DJ. Inpatient Falls: Defining the Problem and Identifying Possible Solutions. Part II: Application of Principles to Hospital Falls. The Neurohospitalist. Published online 5 February Cumbler EU and Simpson JR. Code Stroke: Multicenter Experience with In-Hospital Stroke Alerts. Journal of Hospital Medicine. Published online 24 December

7 Jennifer Simpson, MD, Curriculum Vitae, Page 7 7. Leppert MH, Campbell JD, Simpson JR, Burke JF. Cost-Effectiveness of Intra-Arterial Treatment as an Adjunct to Intravenous Tissue-Type Plasminogen Activator for Acute Ischemic Stroke. Stroke Jul;46(7): Case D, Seinfeld J, Kumpe D, Folzenlogen Z, Jones W, Simpson JR, Hughes R. Acute Posterior Multifocal Placoid Pigment Epitheliopathy Associated with Stroke: A Case Report and Review of the Literature. Journal of Stroke and Cerebrovascular Diseases. Published online 12 August Poisson SN, Simpson JR. What is the appropriate medical and interventional treatment for hyperacute ischemic stroke? The Hospitalist April Korb PJ, Scott SJ, Franks AC, Virapongse A, Simpson JR. Coding and Billing Issues in Hospital Neurology Compensation. Neurology Clinical Practice. In Press. Non-Peer Reviewed Publication: 11. Levin D, Furfari K, Rosenthal L, Simpson, JR, Zehnder N. In the Literature: The latest research you need to know. The Hospitalist. November 1, 2011; 15(11) Anand S, Cho, D, Friedman Y, Kim HW, Saul D, Cumbler E, Sweigart JR, Furfari K, Thurman L, del Pino-Jones AK, Simpson JR, West M, Zehnder N. In the Literature: The latest research you need to know. The Hospitalist. October 1, 2012; 16(10) 13. Graves A, Case D, Gupta R, Pulido A, Rapp K, Simpson JR, Smith D, Jones WJ. Comprehensive stroke Centers: Recognizing the Need for Complex Stroke Care and Interventional Radiology s Contribution. Semin Intervent Radiol Sep;30(3): Cumbler EU, Simpson JR, Virapongse A, Antar A, Czernic Z, Nogar C, King C, Jones C. Reviews of Research on Haloperidol and ICU Delirium, Proton Pump Inhibitors, Thrombolytics and Stroke. The Hospitalist. December 1, Online Book Chapter: 15. Simpson, JR. Brain Abscess in Clinical Decision Support: Hospital Medicine, edited by Wiese J, Auerbach A, Glasheen J, Li J Decision Support in Medicine, LLC. Wilmington, DE Book Chapter: 16. Korb PK, Simpson JR. Approach to Acute Visual Changes, Abnormal Eye Movements, and Double Vision. In: Salardini A, Biller J. The Hospital Neurology Book. 1 st Ed. New York, NY: McGraw Hill Education; Gupta RK, Simpson JR, Kumpe DA. Acute Ischemic Stroke: Endovascular Management. In: Kandarpa K, Macahan L, Durham JD. Handbook of Interventional Radiologic Procedures. 5 th Ed. Philadelphia, PA: Wolters Kluwer; Abstract Presentations: 1. Simpson JR, Zahuranec DB, Sanchez BN, Lisabeth LD, Smith MA, Garcia NM, Morgenstern, LB. Mexican Americans with Atrial Fibrillation and Stroke have a Higher Risk of Recurrent

8 Jennifer Simpson, MD, Curriculum Vitae, Page 8 Stroke than Non-Hispanic Whites. Presented at American Neurological Association Annual Meeting, October 12, Simpson, JR. Stroke Quality Measures. Presented at University of Michigan Neuroscience Day, May 12, Simpson JR, Marin H, Penrose T, Mitisas P. Interventional Therapy for Acute Stroke is Associated with Poor Outcomes. American Academy of Neurology April 25, Simpson JR, Silver B. Patent Foramen Ovale and Atrial Septal Defect Closure Outcomes. Presented at Henry Ford Hosptial Resident Research Forum, February 4, Fatihe M, Graves A, Casper C, Simpson JR. Development of a Multidisciplinary Transient Ischemic Attack (TIA) Clinic at the University of Colorado Hospital. Rocky Mountain Hospital Medicine Symposium August 14, Winner, Best Clinical Innovation Poster. 6. Pulido A, Simpson JR. Emergency Medicine Residents Experience with IV tpa in Acute Stroke. Presented at the American Neurological Association October 13, Miravalle A, Simpson JR, Rich A. Assessing Milestone Levels for Neurology Residents on Patient Simulations and Case Based Learning Tests. Presented at the 2014 ACGME Annual Education Conference February 27-March 2, Simpson, JR, Graves A, Burrus A, Case DE, Denton CJ, Gebhard L, Grant MD, Smith DA, Gupta RK. Improvement of Door to Groin Time for Endovascular Therapy in Acute Ischemic Stroke Using Quality Improvement Methods. Presented at the 2014 International Stroke Conference, February 13, Simpson, JR, Graves A, Burrus A, Case DE, Denton CJ, Gebhard L, Grant MD, Smith DA, Gupta RK. Improvement of Door to Groin Time for Endovascular Therapy in Acute Ischemic Stroke Using Quality Improvement Methods. Presented at the 25 th Annual Rocky Mountain Interprofessional Research and Evidence Based Practice Symposium, March 7, Burrus A, Smith D, Gupta R, Gebhardt L, Simpson JR, Denton CJ. Education In The Interventional Radiology Department To Sustain Improvement In Intra-arterial Treatment Times For Acute Stroke. Presented at Association of Radiology and Imaging Nurses 2014 Spring Convention, March Korb PJ, Franks AC, Scott SJ, Virapongse A, Simpson JR. Neurohospitalist Billing Practices Compared to Hospital Medicine. Second Annual Neurohospitalist Society Meeting, September 27, Salimian S, Simpson JR. Vertebral Artery Occlusion in a Patient with Rheumatoid Arthritis and Atlantoaxial Instability. Second Annual Neurohospitalist Society Meeting, September 27, Finseth T, Hampton C, Simpson JR. Faciobrachiodystonic Seizures: A Rare, Treatable Syndrome Not To Miss. Second Annual Neurohospitalist Society Meeting, September 27, Leppert M, McConnell B, Finseth T, Simpson JR. Challenge of Diagnosing Neuromyelitis Optica in an Elderly Patient without the Use of MRI. Second Annual Neurohospitalist Society Meeting, September 27, 2014.

9 Jennifer Simpson, MD, Curriculum Vitae, Page Snyder M, Newsome F, Holden M, Limon S, Cox S, Case K, Neumann R, Jones WJJ, Poisson S, Simpson JR, Hartson K. Challenges, Successes, and Nurse Perceptions of the Implementation of the NIH Stroke Scale on Multiple Units. Presented at the 2015 International Stroke Conference February 11, Anderson ME, Glasheen JJ, Godleski M, Simpson JR, and Tad-y D. Stroke Systems of Care Curriculum for Hospitalist Residents. Poster presented at the 3 nd Annual Educational Scholarship and Innovation Symposium. February 11, Aurora, CO. 17. Scott SJ, Anoff DL, Korb PJ, Simpson JR, Virapongse A. A Breakdown of Level One Inpatient Admissions at an Academic Medical Center. Society of Hospital Medicine Annual Meeting, Research Category, March 30, Virapongse A, Scott SJ, Korb PJ, Simpson JR. Increasing Billing Accuracy of Inpatient Visits in a Multispecialty Academic Hospital Group Using PDSA Methodology. Society of Hospital Medicine Annual Meeting, Innovations Category, March 30, De Andrae Pereira R, Groves S, Medrano D, Muszelik M, Ross M, Rovira M, Pierce RG, Sweigart JR, Tad-y D, Limon S, Robison Z, Simpson JR. Scripting Multi-Disciplinary Rounds Enhances Efficient and Productive Coordination of Care For Stroke Patients. Society of Hospital Medicine Annual Meeting, Innovations Category, March 30, Korb PK, Franks AC, Scott SJ, Virapongse A, Simpson JR. Neurohospitalist Billing Practices Compared to Hospital Medicine. American Academy of Neurology 67 th Annual Meeting, April 23, Miravalle A, Frey L, Simpson JR, West M, Rich A. Leaders in Education, Administration and Research: Developing a Leadership Curriculum in a Neurology Residency Program. Poster and abstract presented at the Annual American Academy of Neurology annual meeting, Washington, D.C. April 21, Miravalle A, Corboy J, Frey L, Jones W, Simpson JR, Quan D, Rich A. Increasing Faculty Involvement in Educational Activities. Poster presentation at the Annual American Neurologic Association meeting, Chicago, IL September 28, Oral Presentations 1. Simpson JR, Zahuranec DB, Sanchez BN, Lisabeth LD, Smith MA, Garcia NM, Morgenstern, LB. Mexican Americans with Atrial Fibrillation and Stroke have a Higher Risk of Recurrent Stroke than Non-Hispanic Whites. American Neurological Association Special Interest Group, October 11, Miller DM, Khan M, Simpson JR, Russman A, Schultz L, Mitsias P. Outpatient Cardiac Telemetry Detects A High Rate of Atrial Fibrillation Among Patients with Cryptogenic Cerebral Ischemia. Presented by DM Miller at International Stroke Conference February 2, Simpson JR. Success Story: Improving Time of Hospital Discharge with Quality Improvement Methods. Association of University Professors of Neurology 2013 Leaders Forum. New Orleans, LA, October 12, 2013.

10 Jennifer Simpson, MD, Curriculum Vitae, Page Faithe M, Simpson, JR. Development of a Multidisciplinary Transient Ischemic Attack Clinic. Podium presentation at the 25 th Annual Rocky Mountain Interprofessional Research and Evidence Based Practice Symposium, March 7, Korb PJ, Franks AC, Scott SJ, Virapongse A, Simpson JR. Neurohospitalist Billing Practices Compared to Hospital Medicine. Presented by PJ Korb at Second Annual Neurohospitalist Society Meeting, September 27, 2014.

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