Curriculum Vitae Department of Neurology University of Colorado Medical Center Denver, Colorado

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1 Robert W. Pratt, M.D. Curriculum Vitae CURRENT APPOINTMENTS 2016-present 2017-present Assistant Professor Department of Neurology University of Colorado Medical Center Denver, Colorado Clinical Site Director of Neurology Education at Denver Health University of Colorado School of Medicine EMPLOYMENT 2016-present Neurologist Denver Health and Hospital Denver, Colorado Neurologist / Partner Blue Sky Neurology Englewood, Colorado Director, Neurodiagnostic Laboratory, Swedish Medical Center Stroke Program Director, Presbyterian-St. Luke s Hospital, Denver, CO -Led team for Recertification as Primary Stroke Center, Jan Led team for Recertification as Primary Stroke Center, Jan Led team for Certification as Primary Stroke Center, Feb 2012 ACTIVITIES & MEMBERSHIPS 2001-present 2005-present 2005-present American Academy of Neurology Colorado Neurological Institute, Englewood, CO Colorado Society of Clinical Neurologists BOARD CERTIFICATIONS 2005-present American Board of Psychiatry and Neurology (ABPN)

2 American Board of Electrodiagnostic Medicine (ABEM) 2010-present Neurocritical Care (United Council for Neurologic Subspecialties) MEDICAL LICENSURE 2005 Colorado: DEA License: BP EDUCATION Neurological Institute of New York, Columbia University Postdoctoral fellowship in EMG and neuromuscular disease Neurological Institute of New York, Columbia University Resident, neurology Beth Israel Medical Center Intern, internal medicine Columbia University College of Physicians & Surgeons M.D Yale University New Haven, CT B.S., biology EMPLOYMENT 9/1998-5/1999 Cinterandes Foundation volunteer, Cuenca, Ecuador Activities included serving patients at primary care clinics, outpatient neurology clinic, and regional hospital neurology service; informal talks to medical students; surgical assistance and pre-op/post-op checks of patients with the foundation s mobile surgical unit U.S. Peace Corps volunteer, Mizque, Bolivia Projects included organization, construction, and education in maintenance of tree nurseries; construction of 30 irrigation wells with subsistence farmers; farmer education in techniques of soil conservation

3 LECTURES AND PUBLICATIONS Original Articles Chang I, Pratt R. Neurohospitalists: An Emerging Subspecialty. Current Neurology and Neuroscience Reports 2012 Aug: 12(4): Ganguly A, Oo TF, Rzhetskaya M, Pratt R, Yarygina O, Momoi T, Kholodilov N, Burke RE. CEP11004, a novel inhibitor of the mixed lineage kinases, suppresses apoptotic death in dopamine neurons of the substantia nigra induced by 6-hydroxydopamine. J Neurochem Jan;88(2): Pratt R, Mayer S. Normal pressure herniation. Neurocrit care. 2005;2(2): Review article Textbook chapter Online publications Pratt R, Weimer LH. Medication and toxin-induced peripheral neuropathy. Semin Neurol Jun;25(2): Pratt R, Adams D, Balmaceda C. Hematological and related diseases. In: Rowland LP, ed. Merritt s Neurology, 11 th edition. Philadelphia, PA: Lippincott Williams & Wilkins; Pratt R. Kennedy disease. In: Gilman S, ed. Medlink Neurology. San Diego, CA: January Updated January Pratt R. Motor and multifocal motor neuropathies. In: Gilman S, ed. Medlink Neurology. San Diego, CA: August Pratt R, Rowland LP. Idiopathic asymptomatic hyper-ck-emia. In: Gilman S, ed. Medlink Neurology. San Diego, CA: Revised Pratt R. Mercury neuropathy. In: Gilman S, ed. Medlink Neurology. San Diego, CA: June Lectures Pratt R. What s in a Name? Neurologic Eponyms and the Physicians Behind Them. University of Colorado Grand Rounds. December Pratt R. Posterior Reversible Encephalopathy Syndrome. Lecture given at Presbyterian St. Luke s 2016 Stroke Symposium. May Pratt R. Posterior Circulation Ischemic Stroke. Lecture given at Presbyterian St. Luke s 2015 Stroke Symposium. October Pratt R. Cerebral Arterial Dissection. Lecture given at Presbyterian St. Luke s 2014 Stroke Symposium. May 2014

4 Pratt R. Cerebral Venous Thrombosis. Lecture given at Presbyterian St. Luke s 2013 Stroke Symposium. May Pratt R. Stroke Subtypes and Management Pearls. Lecture given at Presbyterian St. Luke s 2012 Stroke Symposium. May Pratt R. Examination of the Comatose Patient. Lecture given at 2 nd Annual Stroke Care is a Team Effort: A Collaborative Approach to Improving the Outcome of Stroke Nursing Conference, Denver, CO. Dec Pratt R. Subarachnoid Hemorrhage. Stroke Noon Conference, Swedish Medical Center, October RESEARCH Site Principle Investigator: APEX Study: Multicenter, Randomized, Active-Controlled Efficacy And Safety Study Comparing Extended Duration Betrixaban With Standard Of Care Enoxaparin For The Prevention Of Venous Thromboembolism In Acute Medically Ill Patients Sub-Investigator, PRISMS study: Phase IIIb, double blind, randomized clinical research study evaluating the safety and efficacy of IV alteplase in AIS patients with mild stroke present Sub-Investigator, RESPECT-ESUS: Randomized, Double-blind, Evaluation in Secondary Stroke Prevention Comparing the EfficaCy and Safety of the Oral Thrombin Inhibitor Dabigatran Etexilate (110 mg or 150 mg, Oral b.i.d.) Versus Acetylsalicylic Acid (100 mg Oral q.d.) in Patients With Embolic Stroke of Undetermined Source present Sub-Investigator, Safety of Intravenous Thrombolysis for Wake-up Stroke Sub-Investigator, A Multicenter Observational Study to Evaluate the Simplified-STroke REhabilitation Assessment of Movement (S- STREAM) Scale in Subjects Obtained Between24 and 48 hours of a Nonhemorrhagic Ischemic Stroke Sub-Investigator, The THERAPY Trial: The Radomized, Concurrent Controlled Trial to Assess the Penumbra System s Safety and Effectiveness in the Treatment of Acute Stroke Sub-Investigator, Prospective, Double-Blind, Sham-Controlled, Randomized, Multi-Center Saftey and Preliminary Efficacy Study of IV rt-pa versus IV rt-pa plus Transcranial Laser Therapy (TLT)

5 Principle Investigator, ENGAGE AF-TIMI 48: Study for evaluation of efficacy and safety of DU-176b versus warfarin in subjects with atrial fibrillation with resent stroke Sub-Investigator, POINT: Platelet-Oriented Inhibition in New TIA and minor ischemic stroke (POINT) Trial, a randomized, doubleblind, multicenter clinical trial Present. Sub-Investigator, Secondary Prevention of Small, Subcortical Stroke (SS3) Site Principle Investigator: TIMI-50 TRA: Direct Oral Thrombin Inhibitor in Secondary Stroke Prevention Sub-investigator: IMS-III: To assess whether IV and IA approach to recanalization is superior to standard IV rt-pa (Activase ) alone when initiated within three hours of acute ischemic stroke onset. NIH funded present. RESPECT-PFO: Closure vs. medical treatment in PFO patients with stroke. AGA Medical Corp present. Sub-investigator: 2007 Use of iv-tnk in Acute Stroke Study to Sub-investigator: Photothera: Treatment of acute ischemic stroke with the NeuroThera Laser System within 24 hours from stroke onset. Photothera, Inc Sub-investigator: ImaRx: MRX-801 with continuous ultrasound in acute ischemic stroke receiving IV tpa. ImaRx Therapeutics, Inc Sub-investigator: SAINT II Trail (SA-NXY-0007). A Double- Blind, Randomized, Placebo-Controlled, Parallel Group, Multicenter, Phase IIb/III Study to Assess the Efficacy and Safety of Intravenous NXY-059 in Acute Ischemic Stroke (SAINT II). AstraZeneca Sub-investigator: PRoFESS--Prevention Regimen For Effectively avoiding Second Strokes: A double-blind, active and placebo controlled study of Aggrenox vs. clopidogrel, with and without Micardis in Stroke. Boehringer/Ingelheim, 2004-present. Sub-investigator: Novo7: Activated Recombinant Factor VII (NovoSeven /Niastase ) in intracerebral hemorrhage. NovoNordisk

6 AWARDS Faculty Teaching Award for Excellence in Resident Education, University of Colorado School of Medicine, Department of Neurology Nominee, resident teaching award, Columbia-Presbyterian Hospital Nominee, resident teaching award, Columbia-Presbyterian Hospital OTHER 1991 Bronze medalist, U.S. National Rowing Championships

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