CURRICULUM VITAE. Drexel College of Medicine Graduate Student Association, Vice President,
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1 CURRICULUM VITAE Megan C. Wright, Ph. D. Education: Drexel University College of Medicine Laboratory of Young-Jin Son, Ph.D., Associate Professor, College of Medicine Philadelphia, Pennsylvania Doctor of Philosophy in Neuroscience, 2007 Drexel College of Medicine Graduate Student Association, Vice President, Drexel College of Medicine, Graduate Neuroscience Program, Curriculum Committee, Drexel College of Medicine, Graduate Neuroscience Program, Student Steering Committee, Drexel College of Medicine, Annual Research Day Committee, Drexel College of Medicine, Graduate Student Association, Secretary, Drexel University Philadelphia, Pennsylvania Bachelor of Science in Biomedical Science, 2002 Honors Program Dean s Honors List, Dean s Award for Outstanding Student Leadership, 2002 Drexel University, Student Council Member, Employment and Positions Held: Assistant Professor of Biology Arcadia University Department of Biology Glenside, PA September 2010 present Adjunct Faculty The Johns Hopkins School of Medicine Department of Neurology Baltimore, MD September 2010 present Postdoctoral Fellow
2 The Johns Hopkins School of Medicine Department of Neurology Laboratory of Ahmet Hoke, M.D., Ph.D., Professor Baltimore, MD January 2008-August 31, 2010 Research Assistant MCP Hahnemann University Laboratory of Terry Heimann-Patterson, MD and Jeffery Deitch, PhD Clinical Research Assistant MCP Hahnemann University Amyotrophic Lateral Sclerosis Clinic Advisor with Terry-Heimann Patterson, MD Peer Reviewed Publications: Abstracts: MC Wright, A Kim, YJ Son. Subcutaneous administration of muscarinic antagonists and triple-immunostaining of the Levator auris longus muscle in mice. The Journal of Visual Experiments. 2011;(55). pii: 3124 AC Lepore, C Tolmie, J O Donnell, MC Wright, C Dejea, B Rauck, A Hoke, AR Ignagni, RP Onders and NJ Maragakis, Peripheral Hyperstimulation Alters Site of Disease Onset and Course in SOD1G93A Rats. Neurobiology of Disease Sep; 39(3): MC Wright, S Potluri, X Wang, E Dentcheva, D Gautam, A Tessler, J Wess, and YJ Son. Distinct muscarinic acetylcholine receptor subtypes contribute to stability and growth, but not compensatory plasticity, of neuromuscular synapses. The Journal of Neuroscience Nov 25; 29(47): Image from manuscript selected for cover image MC Wright, WJ Cho, YJ Son. Distinct patterns of motor nerve terminal sprouting induced by ciliary neurotrophic factor vs. botulinum toxin. Journal of Comparative Neurology. 2007; Sep 1; 504(1):1-16. Image from manuscript selected for cover image MC Wright, YJ Son. Ciliary neurotrophic factor is not required for terminal sprouting and compensatory reinnervation of neuromuscular synapses: re-evaluation of CNTF null mice. Experimental Neurology. 2007; Jun; 205(2): M.C. Wright, R. Mi, E. Connor, N. Reed, A. Vyas, G. Coppola, D.H. Geschwind, T. Brushart, A. Hoke. Identification of two novel Schwann-cell derived growth factors and their role in modality-specific peripheral nerve regeneration. Peripheral Nerve Society, 2011.
3 M.C. Wright, E.C. Connor, T. Sharma, G. Copolla, D. Geschwind, A. Hoke. Examination of molecular changes in chronically denervated Schwann cells. Peripheral Nerve Society, M.C. Wright, R. Mi, E. Connor, N. Reed, A. Vyas, G. Coppola, D.H. Geschwind, T. Brushart, A. Hoke. Identification of two novel Schwann-cell derived growth factors and their role in modality-specific peripheral nerve regeneration. Society for Neuroscience, M.C. Wright, E. Connor, T. Sharma, G. Coppola, D.H. Geschwind, A. Hoke. Examination of molecular changes in chronically denervated Schwann cells. Society for Neuroscience, MC Wright, A. Yaron, M. Fainzilber, and A. Hoke. Brn3a is upregulated in Schwann cells associated with injured axons. Society for Neuroscience, MC Wright, M. Belzberg, EC Conner, G. Coppola, DH Geshwind, T. Brushart, and A. Hoke. Differential gene expression in denervated sensory and motor Schwann cells. Society for Neuroscience, R. Mi, MC Wright, R. Thakrar, W. Chen, L. Xue, SW Morris, M. Vigny, A. Hoke. Anaplastic lymphoma kinase (ALK) and motor nerve regeneration. Society for Neuroscience, AC Lepore, C. Tolmie, J. O'Donnell, MC Wright, C. Dejea, B. Rauck, A. Hoke, AR Ignagni, RP Onders, NJ Maragakis. Peripheral hyperstimulation alters site of disease onset and course in SOD1G93A rats. Society for Neuroscience, 2009 MC Wright, G. Coppola, DH Geshwind, T. Brushart, and A. Hoke. Differential gene expression in denervated sensory and motor Schwann cells. Peripheral Nerve Society, MC Wright, Potluri S. Dentcheva E, D. Gautm, Keeler B, J. WESS and Y.-J. Son. Pharmacological and genetic inhibition of muscarinic acetylcholine receptors induces disorganization of neuromuscular junctions in a receptor subtype-specific fashion. Society for Neuroscience, MC Wright, D. Gautam, J. Wess and Y.-J. Son. Reduced synaptic size and enhanced paralysis-induced sprouting of motor nerve terminals in mice lacking M5 muscarinic acetylcholine receptors. Society for Neuroscience, MC Wright, D. Gautam, J. Wess and Y.-J. Son Reduced synaptic size and enhanced paralysis-induced sprouting of motor nerve terminals in mice lacking M5 muscarinic acetylcholine receptors. Drexel Research Day Symposium, M.C. Wright, S. Jawaid, D. Gautam, J. Wess, and Y.J. Son. Reactive plasticity of neuromuscular junctions in mice lacking muscarinic acetylcholine receptor subtypes. Society for Neuroscience, MC Wright, M. Sendtner, and Y.J. Son. Endogenous CNTF is not required for reactive sprouting of motor nerve terminals. Society for Neuroscience, 2005.
4 MC Wright and Y.J. Son. "Perisynaptically trapped sprouting of motor nerve terminals induced by exogenous CNTF: Implications for neuromuscular repair. " Drexel Research Day Symposium, MC Wright, W.J. Cho, J. Xu, and Y.J. Son. Distinctive outgrowth patterns of nerve terminal sprouting induced by CNTF vs. BOTX: Implications for neuromuscular repair. Society for Neuroscience, MC Wright, W.J. Cho, J. Xu, and Y.J. Son Distinctive outgrowth patterns of nerve terminal sprouting induced by CNTF vs. BOTX: Implications for neuromuscular repair. Drexel Research Day Symposium, Peer Reviewed Scientific and Professional Presentations: Identification of two novel Schwann cell derived factors and their role in modality-specific peripheral nerve regeneration. Peripheral Nerve Society, Potomac Maryland, June Differential gene expression in denervated sensory and motor Schwann cells. Peripheral Nerve Society, Wurzburg, Germany, July Differential gene expression in denervated sensory and motor Schwann cells. Data Blitz for American Neurological Association, Baltimore, MD, October Non-Peer Reviewed Presentations: Promoting peripheral nerve regeneration: identification of novel, injury-induced Schwann cell factors. Shriners Hospitals Pediatric Research Center (Center for Neural Repair and Rehabilitation), Temple University School of Medicine. May 31, "Perisynaptically trapped sprouting of motor nerve terminals induced by exogenous CNTF: Implications for neuromuscular repair. Drexel University College of Medicine, October Membership in Scientific/Professional Organizations: Peripheral Nerve Society, 2009 present Association for Women in Science, 2006 present Society for Neuroscience, 2002 present Honors and Awards: P.K. Thomas M.D. Fellowship Award (Best Young Basic Scientist Award) Potomac, MD 2011 Travel Award Potomac, MD 2011
5 Peter J. Dyck, M.D. Fellowship Award Peripheral Nerve Society 2009 Travel Award Wurzburg, Germany 2009 Drexel College of Medicine Alumni Association Award Drexel College Alumni Association Drexel College of Medicine Annual Discovery Research Day Poster Presentation 2 nd Place 2006 Drexel College of Medicine Annual Discovery Research Day Platform Presentation 1 st Place 2005 Janet Steen Student Research Fellowship Amyotrophic Lateral Sclerosis (ALS) Hope Foundation Hahnemann University Hospital Current Teaching Responsibilities in the Entry-Level Program: Unit 1, Anatomy
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