ALFA -HAPPOM. First International Course on High Altitude Physiology and Physiopathology, from the organism to the molecule. Arica, April 14-29, 2005

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1 ALFA -HAPPOM First International Course on High Altitude Physiology and Physiopathology, from the organism to the molecule Arica, April 14-29, 2005

2 ALFA HAPPOM ALFA is an educational program of cooperation between Europe and Latin America, sponsored and financed by the European Commission. Around 50 programs in each round, in all domains of science. Already three rounds: ALFA I, ALFA II (ours), and ALFA III ALFA HAPPOM is the first program of academical education in the field of High altitude physiology and medicine.

3 ALFA HAPPOM Objectives: Stimulate the development of education and research in the field of High altitude biology by the promotion of an high level group of biologists, physiologists, medical doctors, veterinarians Stimulate the development of basic science, applied knowledge for public health, and scientific cooperation between research laboratories

4 ALFA HAPPOM Ten universities are involved 24 students 14 professors 12 tutors Total budget of euros 75% financed by the EU 25% financed by the Universities

5 ALFA HAPPOM Selection of students in their university of origin (March 2005) International course in Arica (April 2005) Selection of 12 students (28 April 2005) Language formation (May to September 2005) Research grant in European universities (October-November 2005) (2 students in each university) General meeting in Lyon (December 2005) Research grant in Latin American universities (2006) (one month) Visit of european tutors to Latin America (2 weeks, 2006)

6 In the future Organize this International Course every second year and promote the cooperation between European Universities and South American Universities, research programs, exchange of PhD students, co-tutored thesis

7 ALFA HAPPOM ARICA course Sunday 17 th 08:30 09:15 Opening session 09:15 10:30 Introduction: Environment of high altitude JP Richalet 11:00 13:00 Muscle physiology in hypoxia, aerobic, anaerobic P Cerretelli 15:00 16:30 Genes and environmental factors C Godinot 17:00 18:30 The economy of exercise in man: normoxia vs hypoxia C Marconi

8 ALFA HAPPOM ARICA course Monday 18 th 08:30 10:30 Limits of human tolerance to hypoxia P Cerretelli 11:00 13:00 Candidate genes and gene complexes C Godinot 15:00 16:30 Genetic influence on factors of oxygen transport C Marconi 17:00 18:30 Pregnancy at high altitude A Llanos Tuesday 19 th 08:30 10:30 Blood at high altitude K Kirsch 11:00 13:00 Molecular adaptation to hypoxia: the proteome approach P Cerretelli 15:00 16:30 Regulation of body fluid and water-salt balance K Kirsch 17:00 18:30 Regulation of blood ph: revisiting the lactate paradox C Marconi 21:00 22:00 Meetings between students and lecturers (planning research programmes)

9 ALFA HAPPOM ARICA course Wednesday 20 th 08:30 10:30 Cardiovascular physiology at high altitude JP Richalet 11:00 13:00 Lung volumes, mechanics of breathing, gas exchange F Leon-Velarde 15:00 16:30 Chronic mountain sickness H Spielvogel 17:00 18:30 Control of ventilation F Leon-Velarde Thursday 21 st 08:30 10:30 AMS, HACE, HAPE, neurological disorders JP Richalet 11:00 13:00 Pulmonary circulation at high altitude J Coudert 15:00 16:30 Prevention of altitude-induced diseases, acclimatization JP Richalet 17:00 18:30 Training in chronic hypoxia and acute normoxia H Spielvogel

10 ALFA HAPPOM ARICA course Friday 22 nd 08:30 10:30 Adaptation of mammals and birds at high altitude F Leon-Velarde 11:00 13:00 Adaptation of oxygen transport F Leon-Velarde 15:00 16:30 Nutrition, oxidative stress and anti-oxidant status C Behn 17:00 18:30 Immunology and high altitude C Behn Saturday 23 rd 09:00 18:00 Visit to Putre and Chungara Sunday 24 th Day off

11 ALFA HAPPOM ARICA course Monday 25 th 08:30 10:30 Endocrine system (glucose, gonades, growth) G Gonzales 11:00 13:00 Endocrine system (T4, PO 4 -Ca, corticotropic) G Gonzales 15:00 16:30 Foetal physiology and pathology at high altitude A Llanos 17:00 18:30 Effects of malnutrition on aerobic and anaerobic metabolism J Coudert 21:00 22:00 Meetings between students and lecturers (planning research programmes) Tuesday 26 th 08:30 10:30 Exercise: adaptation of oxygen transport, gas exchange J Coudert 11:00 13:00 Training at high altitude and for competition at altitude G Viscor / JP Richalet 15:00 16:30 Limiting factors of physical performance JP Richalet / G Viscor 17:00 18:30 Oxygen sensing JM Péquignot

12 ALFA HAPPOM ARICA course Wednesday 27 th 08:30 10:30 Central nervous system and hypoxia JM Péquignot 11:00 13:00 Comparative aspects of aerobic and anaerobic metabolism G Viscor 15:00 16:30 Animal diseases at high altitude D Chauca 17:00 18:30 Diet and performance at extreme altitude G Viscor Thursday 28 th 9:00 12:00 Examination 14:00 16:00 Correction 17:00 Proclamation of results 18:00 Debreifing 19:00 Farewell party Friday 29 th Departure from Arica

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