THE PHARYNX. Mohammed ALESSA MBBS, FRCSC Assistant professor Consultant Otolaryngology, Head & Neck Surgery
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1 THE PHARYNX Mohammed ALESSA MBBS, FRCSC Assistant professor Consultant Otolaryngology, Head & Neck Surgery
2
3 Cavity of the pharynx
4
5 The Nasopharynx
6
7 The Oropharynx
8 The oropharynx
9 Tonsils Size
10 Grading the Size of Tonsils Grading system: A. 0 tonsils in fossa B. +1 tonsils less than 25% C. +2 tonsils less than 50% D. +3 tonsils less than 75% E. +4 tonsils greater than 75%
11
12 The Laryngopharynx (Hypopharynx)
13 Pharyngeal Wall Mucous membrane Submucosa Muscular layer Fibrous layer (Buccopharyngeal fascia)
14 Mucous membrane Nasopharynx Ciliated columnar epithelium Oro and hypopharynx Stratified squamous epithelium
15 Submucosa Nerves, blood vessels, and lymphatics Mucous and salivary glands Subepithelial lymphoid tissue
16 Subepithelial lymphoid tissue
17 Characteristics of Waldeyer s Ring No afferents Efferent to deep cervical nodes No capsule except the palatine tonsils
18 Pharyngeal Wall Mucous membrane Submucosa Muscular layer Fibrous layer Buccopharyngeal fascia
19 Muscular layer External: The three constrictors -1 superior 2 middle 3 - inferior Internal: Stylopharyngeus Salpingopharyngeus Palatopharyngeus
20
21 Pharyngeal Wall Mucous membrane Submucosa Muscular layer Fibrous layer (Buccopharyngeal fascia)
22 Nerve Supply Trigeminal Glossopharyngeal Vagus Sympathetic: cervical ganglia
23 Arterial from the external carotid artery Ascending pharyngeal The lingual artery The facial artery The maxillary artery Venous drainage to the internal jugular Blood supply
24 Lymphatics Retropharyngeal nodes Deep cervical (jugular) nodes
25 Jugulo-Diagastic nodes
26 Physiology of the Pharynx
27 Functions of the pharynx Respiratory Channel Deglutition
28 Deglutition Oral Stage Pharyngeal Stage Esophageal stage
29 Functions of the pharynx Respiratory Channel Deglutition Speech Taste Immunity
30 Immunity function of the pharynx Production of immunoglobulins, plasma cells and lymphocytes by the subepithelial lymphoid tissue
31 DISEASES OF THE NASOPHARYNX
32 ACUTE INFECTION OF NASOPHARYNX Pathologically: is a part of acute rhinitis (common cold) Clinically: has no specific clinical features
33 ADENOIDS
34 DEFINITION Hypertophy of the nasopharyngeal tonsils sufficient to produce symptoms
35 CLINICAL FEATURES Usually in children Nasal obstruction Mouth breathing Snoring, sleep disturbance, apnea etc Ear symptoms due to Eustachian tube obstruction Adenoid face
36
37 EXAMINATION
38 EXAMINATION
39 EXAMINATION
40 Normal nasopharynx Adenoid
41
42 PLAIN X- RAY Normal Adenoid
43
44
45 TREATMENT Adenoidectomy
46
47 Local Contraindication of Adenoidectomy Palatopharyngeal incompetence
48 DISEASES OF THE OROPHARYNX
49 ACUTE INFECTIONS OF THE OROPHARYNX Acute tonsillitis Acute non-specific pharyngitis Acute diphtheria Infectious mononeuclosis Vincent s angina Scarlet fever Moniliasis
50 ACUTE TONSILLITIS
51 ETIOLOGY A disease of childhood, with a peak incidence at about 5 to 6 years of age
52 CAUSATIVE ORGANISMS Viral: Influenza, Parainfluenza, Rhinovirus, Adenoviruses, Respiratory syncytial virus, Coronaviruses Bacterial: Beta Hemolytic Streptococcus (Group A) Others: Strept pneumonia, H. infleunzae, Staph. aurius etc
53 Clinical features Malaise, fever, headache, limb and back pain Sore throat, odynophagia, dysphagia Otalgia
54 THROAT EXAMINATION A. Parenchymatous tonsillitis B Follicular tonsillitis
55
56 C. Membranous tonsillitis
57 NECK EXAMINATION Enlargement and tenderness of the jugulodigastric lymph nodes
58 INVESTIGATIONS Throat swab CBC
59 TREATMENT Symptomatic & supportive treatment Antibiotics Penicillin V for 5-7days drug of choice Erythromycin second line Amoxicillin and Ampicillin better absorption
60 General: COMPLICATIONS OF ACUTE TONSILLITIS Acute rheumatism Acute glomerulonephritis Septicaemia Local: Peritonsillitis & peritnosillar abscess ( Quinsy)
61 PERITONSILLAR ABSCESS (QUINSY) An abscess between the tonsil capsule and the adjacent lateral pharyngeal wall
62 CLINICAL FEATURES More common in adults Usually unilateral Usually follow an attack of tonsillitis Sever pain > one side Unilateral earache and cervical lymphadenitis More odynophagia & drooling Trismus Thickened speech (hot potato voice)
63 EXAMINATION
64 EXAMINATION
65 TREATMENT IV antibiotics Incision and drainage followed by elective tonsillectomy 6-8 weeks later? Hot (abscess) tonsillectomy
66 General: COMPLICATIONS OF ACUTE TONSILLITIS Acute rheumatism Acute glomerulonephritis Septicaemia Local: Peritonsillitis & peritnosillar abscess ( Quinsy) Neck Abscess
67 Neck abscess
68 General: COMPLICATIONS OF ACUTE TONSILLITIS Acute rheumatism Acute glomerulonephritis Septicaemia Local: Peritonsillitis & peritnosillar abscess ( Quinsy) Neck Abscess Parapharyngeal abscess
69
70
71
72 Clinical features of parapharyngeal abscess Systemic manifestations Pain, trismus, swelling
73
74
75 CLINICAL FEATURES Systemic manifestations Pain, trismus, swelling
76 Laboratory and bacteriology CT MRI INVESTIGATION
77 PRINCIPLES OF TREATMENT Secure the airway Antimicrobial therapy Surgical drainage
78 DRAINAGE OF PARAPHARYNGEAL ABSCESS External cervical incision In order to avoid injury to the great vessels
79
80 General: COMPLICATIONS OF ACUTE TONSILLITIS Acute rheumatism Acute glomerulonephritis Septicaemia Local: Peritonsillitis & peritnosillar abscess ( Quinsy) Neck Abscess Parapharyngeal abscess Retropharyngeal abscess
81
82 Anatomy of retropharyngeal space
83 ACUTE RETROPHARYNGEAL ABSCESS Due to suppuration of the retropharyngeal lymph nodes present in the retrophayngeal space
84 CLINICAL FEATURES Systemic manifestations Respiratory obstruction Odynophagia & Dysphagia Swelling of posterior pharyngeal wall (usually unilateral)
85 INVESTIGATION Laboratory and bacteriology Plain X-rays
86 PLAIN X-RAYS Normal Retropharyngeal abscess
87
88 CT
89 MRI
90 TREATMENT OF ACUTE RETROPHAYNGEAL ABSCESS Secure airway Antimicrobial Surgical drainage Trans oral
91 CHRONIC RETROPHARYNGEAL ABSCESS Tuberculous (cold abscess) Usually due to TB spines but may be secondary to TB lymphadentis Symptoms are insidious Treatment is by anti tuberculous medication, repeated aspiration and external drainage
92 Ludwig s Angina Infection of the submandibular space
93 Causes of Ludwig s Angina Usually secondary to dental infection or trauma
94 Presentation of Ludwig s Angina
95 TREATMENT Secure airway Most cases respond to antibiotics Drainage may be needed
96 Complications of neck spaces infections Respiratory obstruction Spontaneous rupture (inhalation pneumonia Extension of infection Other spaces Carotid & internal jugular Mediastinitis
97 ACUTE INFECTIONS OF THE OROPHARYNX Acute tonsillitis Acute non-specific pharyngitis Acute diphtheria Infectious mononueuclosis Vincent s Angina Scarlet fever Moniliasis
98 ACUTE NONSPECIFIC PHARYNGITIS
99 ACUTE INFECTIONS OF THE OROPHARYNX Acute tonsillitis Acute non-specific pharyngitis Acute diphtheria Infectious mononueclosis Vincent s Angina Scarlet fever Moniliasis
100 ACUTE DIPHTHERITIC PHARYNGITIS A severe infection caused by Corynebacterium diphtheriae Affect children at age 2-5 years Spread by droplets or contaminated articles The incidence has fallen markedly because of immunization
101 PATHOLOGY Local grayish membrane (composed of fibrin, leukocytes, and cellular debris) Exotoxins travels to heart and nervous system
102 CLINICAL MANIFESTATIONS Systemic symptoms due to the exotoxins Toxemia Mild fever Tachycardia Paralysis Local manifestations Sore throat Membrane Marked lymphadentitis ( bull neck )
103
104 DIAGNOSIS Isolation of the organism
105 TREATMENT Starts before culture confirmation Airway maintenance Antitoxin Antibiotics (erythromycin, penicillin G, rifampin, or clindamycin)
106 Vaccine PREVENTION
107 COMPLICATIONS Respiratory obstruction Heart failure Muscular paralysis
108 ACUTE INFECTIONS OF THE OROPHARYNX Acute tonsillitis Acute non-specific pharyngitis Acute diphtheria Infectious mononueclosis Vincent s Angina Scarlet fever Moniliasis
109 INFECTIOUS MONONUECLOSIS Systemic infection caused by Epstein-Barr Virus (EBV) Selectively infects B-lymphocytes Clinical disease is usually seen in young adults
110 CLINICAL MANIFESTATIONS Clinical triad Fever Lymphadenopathy Pharyngitis and/or tonsillitis
111 INFECTIOUS MONONUCLEOSIS
112 CLINICAL MANIFESTATIONS Clinical triad Fever Lymphadenopathy Pharyngitis and/or tonsillitis Other clinical findings Splenomegaly 50% Hepatomegaly 10% Rash 5%
113 DIAGNOSIS CBC with differential (atypical lymphocytes) Detection of heterophil antibodies (Paul- Bunnel or Monospot test)
114 TREATMENT Symptomatic & supportive treatment Steroids (severe cases) Avoid ampicillin
115
116 COMPLICATIONS Autoimmune hemolytic anemia Cranial nerve palsies Encephalitis Hepatitis Pericarditis Airway obstruction
117 VINCENT S ANGINA Subacute infection due to Spirochaeta denticolata and Vincent s fusiform bacillus Most commonly in overcrowded conditions trench fever Mild local and systemic symptoms
118 VINCENT S ANGINA
119 VINCENT S ANGINA Subacute infection due to Spirochaeta denticolata and Vincent s fusiform bacillus Most commonly in overcrowded conditions trench fever Mild local and systemic symptoms Management is with penicillin and local oral hygiene
120 SCARLET FEVER
121 SCARLET FEVER
122 SCARLET FEVER
123 FUNGAL PHARYNGITIS
124 CAUSES Long term antibiotics Immunosuppresion (Leukopenia, Corticosteroid therapy etc)
125 CANDIDIASIS (MONILIASIS, THRUSH)
126 CANDIDIASIS (MONILIASIS, THRUSH)
127 Treatment Nystatin Fluconazole
128 CHRONIC TONSILLAR HYPERTOPHY
129 CAUSES Chronic or frequent acute infections Idiopathic (?exaggerated immune response)
130 PRESENTATION Upper airway obstruction Mouth breathing, snoring Disturbed sleep and apnea Pulmonary hypertension, cor pulmonale and heart failure
131
132
133 TREATMENT Tonsillectomy & adenoidectomy
134 CHRONIC INFECTIONS OF THE PHARYNX
135 CHRONIC NON-SPECIFIC PHAYNGITIS Primary Secondary Sinonasal disease Dental infections Chest infections Smoking Gastro esophageal reflux
136 CLINICAL FEATURES Sore throat Irritation Cough O/E
137
138 TREATMENT Treatment of the cause Humidification
139 CHRONIC SPECIFIC PHARYNGITIS Tuberculosis Syphilis Lupus vulgaris Leprosy Sarcoidosis
140 CHRONIC TONSILLITIS Persistent or recurrent sore throat Persistent cervical adenitis Halitosis Congested tonsils
141
142 TREATMENT Tonsillectomy
143 TONSILLECTOMY
144 INDICATIONS Obstructing tonsillar enlargement Suspected malignancy
145
146 INDICATIONS Obstructed tonsillar enlargement Suspected malignancy Repeated attacks of tonsillitis Chronic tonsillitis One attack of quinsy Others
147
148 CONTRAINDICATIONS Bleeding tendency Recent URTI
149 COMPLICATIONS Hemorrhage Primary Reactionary Secondary Respiratory obstruction Injury to near-by structures Pulmonary and distant infections
150 Primary Hemorrhage Bleeding occurring during the surgery Causes Bleeding tendency Acute infections Aberrant vessel Bad technique Management General supportive measures Diathermy, ligature or stitches Packing
151 Reactionary Hemorrhage Bleeding occurring within the first 24 hours postoperative period Causes Bleeding tendency Slipped ligature Diagnosis Rising pulse & dropping blood pressure Rattle breathing Blood trickling from the mouth Frequent swallowing Examination
152 Reactionary Hemorrhage Treatment General supportive measures Take the patient back to OR Control like reactionary hemorrhage
153 Secondary hemorrhage Occur 5-10 days posoperatively Due to infection Treated by antibiotics May need diathermy or packing
154 Pharyngeal (Zenker s) Pouch A mucosal sac protruding through Killian s dehiesence
155 Pathogenesis Most probably related to neuromuscular incoordination? Failure of relaxation of cricopharyngeus?early closure of cricopharyngeus? Spasm of cricopharyngeus
156 Clinical Features Dysphagia Regurgitation Aspiration
157 Clinical examination Barium swallow Diagnosis
158
159 Diagnosis Clinical examination Barium swallow Endoscopy
160 Excision Treatment
161 THANK YOU
1/13/2009. Classification:
SUPPURATIONS OF SPACES RELATED TO THE PHARYNX Assistant Professor, Department of Otolaryngology Head & Neck Surgery Faculty of Medicine, Alexandria University Classification: I. Intratonsillar abscess.
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