Indiana Speech Language Hearing Association

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1 Indiana Speech Language Hearing Association Presenter Bernice K. Klaben, Ph.D. CCC SLP BRS S Associate Professor Director of Clinical Practice UC Otolaryngology Head and Neck Surgery March 31, 2012 Common Adult Voice Disorders: Treatment and Management Upon completion of the presentation, attendees should be able to: Demonstrate knowledge of common adult vocal pathology. Apply behavioral intervention techniques in voice therapy. Describe the evaluation and therapy of irritable larynx. Functions of the Larynx Biological serves to protect the airway. Prevents material from entering the lungs and expel to remove irritants or material Phonatory true vocal folds serves as the sound source. Linguistic features convey the meaning of what we say with intonation, prosody, etc. Suprasegmental patterns of pitch, loudness and resonance are produced at the laryngeal level. Emotional conveys our physical and emotional states. Tension in the larynx affects the vertical height of the larynx. Tension of structures including the tongue, jaw, and pharyngeal area can occur with stress, anxiety or illness. Our mood and affective states are often reflected in the voice. 1

2 Larynx Within the Skeletal Framework From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 165. Subsystems of Voice Production Resonance Phonation Respiration Respiration and Voice Inspiration is an active process enlargement of the thorax and lungs Expiration is mostly passive voicing extends the expiratory phase allowing for voicing and the amount of air pressure used when producing voice largely determines the intensity of the voice 4 5 cm/h2o is required for conversational speech Both inspiratory and expiratory muscles provide the power for voicing. 2

3 Mid sagittal View of the Laryngeal Area From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 169. Structures of the Larynx 13 Muscles 9 Cartilages 4 Joints 1 Bone Lateral Cricoarytenoid (2) Thyroid (1) Cricoarytenoid (2) Hyoid Interarytenoid Two compartments: Transverse (1) Oblique (2) Cricoid (1) Cricothyroid (2) Posterior cricoarytenoid (2) Epiglottis (1) Cricothyroid (2) Arytenoids (2) Thyroarytenoid Corniculates (2) Two compartments Thyromuscularis (2) (Thyro) vocalis (2) Cuneiforms (2) Cartilages of the Larynx From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page

4 Muscles of the Larynx From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 174. Neural Innervations of Intrinsic Laryngeal Muscles VAGUS (CN X) Recurrent Laryngeal Nerve (RLN) innervates all intrinsic muscles (motor) except the cricothyroids. RLN also supplies all sensory information below the vocal folds External branch of Superior Laryngeal Nerve (SLN) innervates the cricothyroid muscles (motor) Internal branch of Superior Laryngeal Nerve provides all the (sensory) information to the larynx Vagus (CN V) The vagus nerve has three nuclei located within the medulla The nucleus ambiguus Motor nucleus of the vagus nerve The dorsal nucleus Efferent fibers of the dosal (parasympathetic) nucleus innervate the involuntary muscles of the bronchi, esophagus, heart, stomach, small intestine, and part of the large intestine The nucleus of the tract of solitarius Afferent fibers of the tract of solitarius carry sensory fibers from the pharynx, larynx, and esophagus 4

5 Superior and Recurrent Laryngeal Nerves From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 184. Extrinsic Muscles of the Larynx Suprahyoids Digastric Anterior belly (CN V) Posterior belly (CN VII) Stylohyoid (CN VII) Mylohyoid (CN V) Geniohyoid (CN XII) Attaches to the hyoid bone and to structures above the hyoid Raises the larynx in the neck Suprahyoid muscles From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page

6 Suprahyoid muscles From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 179. Extrinsic Muscles of the Larynx Infrahyoids Sternohyoid (CN XII) Sternothyroid (CN XII) Omohyoid (CN XII) Thyrohhyoid (CN XII) Muscles attaching below the level of the larynx Often called the strap muscles Lower the larynx Infrahyoid Muscles From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page

7 Phonation Vocal folds abduct during inhalation and adduct during phonation Vibration of the vocal folds create a buzz sound source for voicing Theories of phonation: Van den Berg s Aerodynamic Myoelastic (1958) Hirano s Body Cover (1970 s) Titze s Self Oscillation Theory (1994) Cover Body Model From: Ferrand, C.T. Voice Disorders (2012). Boston, MA:Pearson. Page 35 Coronal Schematic Representation of Vocal Fold Vibration From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page

8 Layers of the Vocal Folds From: Ferrand, C.T. Voice Disorders (2012). Boston, MA:Pearson. Page 34 Assessment Voice Handicap Index (VHI) 30 item questionnaire divided into physical, functional, and emotional categories, 5 point self rating scale. The scale is scored out of total points of low perception of voice related handicap moderate level of handicap >60 severe level of handicap Source: From The Voice Handicap Index (VHI): Development and Validation, Jacobson, B.H., Johnson, A., Grywalski, C., Silbergleit, A., Jacobson, G., Benninger, American Journal of Speech Language Pathology, Vol 6(3), 66 70, Reflux Symptom Index Score Pt s perceived type and degree of severity of symptoms 5 point scale RSI >13 is considered to be abnormal Source: From Validity and Reliability of the Reflux Symptom Index (RSI), Belafsky, P.C., Postma, G.N., Koufman, J.A. Journal of Voice, 16, ,

9 Consensus Auditory Perceptual Evaluation of Voice (CAPE V) Protocol examines vocal features in contexts of sustained vowels, sentences, and connected speech These features are evaluated on a 100 mm horizontal line, where the left of the line indicates a normal voice feature and the right end more severe level Source: From Establishing Validity of the Consensus Auditory Perceptual Evaluation of Voice (CAPE V), Zraick, R.I., Kempster, G.B., Connor, N.P., Thibeault, S., Klaben, B.K., Bursac, Z., Thrush, C.R., Glaze, L.E. American Journal of Speech Language Pathology, 20(1), 14 22, Assessment Glottal Function Index (GFI) Pt self perception of glottal dysfunction 5 pt scale A score >4 reflects problems in vocal function Source: From Validity and Reliability of the Glottal Function Index, Bach, K.K., Belafsky, P.C., Wasylik, K., Postma, G.N., Koufman, J.A. Archives of Otolaryngology Head and Neck Surgery, 131, , Assessment Oral Peripheral Examination Phonatory respiratory efficiency Maximum sustained phonation Normal values seconds for adults s/z ratio indicates sustained voicing and without voicing is approx equal. >1.4 indicates voiced sound cannot be sustain for as long and may indicate impaired glottal efficiency Source: From The s/z ratio as an indicator of laryngeal pathology. Eckel, F., and Boone, D.R. Journal of Speech and Hearing Disorders, 46, ,

10 Assessment Vocal range Pitch range Loudness range Laryngeal function Throat clearing Coughing Laughing Hard glottal attacks Superior View of the Laryngeal Area From: D.R., Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins, page 169. Normal TVF Vocal Folds 10

11 Common Vocal Pathologies Irritable Larynx Cysts Vocal fold paralysis Carcinoma Papilloma Granuloma Bowing Vocal Disorders Muscle Tension Dysphonia Spasmodic dysphonia Causes Malignancy Surgical/traumatic injury Neurological Inflammatory Infectious Idiopathic Intracranial injuries Cranial injuries Neck injuries Chest Vocal Fold Paralysis 11

12 Unilateral Superior Laryngeal Nerve Paralysis Loss of sensation to the supraglottic area can produce symptoms of frequent throat clearing, coughing, vocal fatigue, foreign body sensations. Loss of motor function to the cricothyroid muscle can result in a change in vocal quality with hoarseness and/or diplophonia and decrease in pitch range (especially if trying to sing) Unilateral Recurrent Laryngeal Nerve Paralysis Vocal fold is generally in a paramedial position with loss of abduction Vocal quality is breathy hoarseness Airway is adequate but individuals may complain of shortness of breath with exertion Bilateral Recurrent Laryngeal Nerve Paralysis Usually both RLN are affected Vocal folds usually in a paramedial position Vocal quality is generally good Possible stridor when breathing May need tracheostomy with speaking valve Preservation of airway is most important goal 12

13 Surgical Management of Bilateral TVF Paralysis Laser Cordectomy Laser Cordotomy Lateral Manual Compression Preoperative assessment for surgical medialization laryngoplasty (Isshiki thyroplasty types I and IV and arytenoid adduction) Forceful manual compression of the thyroid and cricoid cartilages modifies the position, shape and tension of the vocal folds. Blaugrund, et al Effects of lateral manual compression upon glottic incompetence: objectives evaluations. Ann Otol Rhino Laryngol, 99(4 pt 1), , Management of Unilateral TVF Paralysis Injectable materials Can be performed in the operating room with trans oral injection or inoffice percutaneous injection/inoffice trans oral injection Radiesse Voice Gel Synthetically derived polymers and no CaHA ~ 3mo Radiesse Voice Synthetic Calcium Hydoxylapatite (CaHA) ~ 12 mo Medialization materials Operative procedure Autologous Fat Gore Tex Silatic 13

14 Voice Therapy for Unilateral Vocal Fold Paralysis Relative to the position of the paralysis and compensation Goal of therapy is to improve glottal closure without developing undesirable compensatory behaviors such as: Anterior Posterior compression Ventricular fold constriction Drawing tongue to the back of the pharynx to help with glottal closure Falsetto voice or abnormal pitch for age and sex of pt Muscular tension of the oral or pharyngeal areas Therapy Sustained phonation at comfort pitch, comfort high and comfort low pitch Glides up and down Vocal Function Exercises Resonant Vocal Exercises Kazoo exercises improvement of the intrinsic musculature strength and agility without supraglottic hyper functioning Forward tone focus without tension of the oral and pharyngeal musculature Use of abdominal breathing instead of upper chest breathing May need to instruct pt to turn head to the side of the paralysis prior to drinking liquids or swallowing food to prevent penetration or aspiration Irritable Larynx Symptoms Chronic cough Muscle tension dysphonia/tenderness in the laryngeal muscles Episodic laryngospasm Globus Increased mucus Dysphonia 14

15 Irritable Larynx Syndrome Morrison and Rammage (2010) Study of pts meeting criteria for irritable larynx syndrome Findings Usually seen in pts manifesting a broad picture of disorders due to CNS hypersensitivity View the irritable larynx syndrome as a central sensitivity syndrome Pts with central sensitivity syndrome may relate to co existent gastroesophageal reflux Source: From The Irritable Larynx Syndrome as a Central Sensitivity Syndrome. Morrison, M., Rammage, L. Canadian Journal of Speech-Language Pathology and Audiology, 34 (4), , Management of Irritable Larynx Syndrome Acquire baseline data History of onset with noted psychological or emotional issues Medical history Phonotraumatic behaviors Triggers or any exacerbating stimuli Muscle tension patterns Dysphonia Respiratory problems Journal daily incidents of triggers Treatment of Irritable Larynx Syndrome Multifactorial management Address sensory stimuli Minimize/eliminate triggers (i.e. odors, stresses, etc) Medical management of laryngopharyngeal reflux Dietary and behavioral lifestyle changes regarding reflux Treatment for sinusitis/rhinitis if involved Treatment for allergies Asthma treatment 15

16 Treatment of Irritable Larynx Syndrome Address habituated patterns by re programming Respiratory retraining and focus on abdominal breathing with sniffing or pursed lips breathing, synchronizing respiration and phonation of prolonged sibilants, humming, counting, spontaneous speech, etc on exhalation Elimination of all throat clearing/coughing with hydration or hard swallow Voice therapy is dysphonic with elimination of hard glottal attacks Vocal hygiene counseling Digital or manual laryngeal massage for musculoskeletal relaxation Treatment of Irritable Larynx Syndrome Address psychological emotional issues Refer to psychologist Medical management for anxiety Address hyper sensitive chronic cough medically if physician diagnosis as laryngeal sensory neuropathy from injury or virus Medically treated by physician Fluid filled sac or semisolid gel like substance Blockage of a mucosal duct Can protrude and involve the vibratory margin of the vocal fold, increasing mass and stiffness of the cover Can cause hoarseness, loss of pitch range, and vocal fatigue Cysts 16

17 Cysts Generally surgical removal Pre surgical therapy Reduce edema and erythema Hydration program Vocal hygiene counseling Reflux management if needed Eliminate phonotraumatic behaviors Vocal exercises to minimize harsh vocal fold contact Mass of tissue consisting of inflammation Consists of large amount of blood cells and connective tissue Created by fibroblasts during wound healing Grows from the base of the wound or injury Vocal process granulomas may be the end result of inflammation caused by chronic irritation Causes LPR Endotracheal intubation Phonotrauma Granuloma Wartlike growth of the epithelium cause by HPV Can be sessile (broad based) or pedunculated (on stalk) Can invade the vocal ligament or thyrovocalis muscle Symptoms hoarseness, difficulty breathing Surgical management Follow up voice therapy to maximize vocal efficiency Papilloma 17

18 Creates a spindle shaped glottal closure Breathy Hoarseness with decreased intensity and vocal fatigue Causes muscle atrophy, neurological, trauma Bowing May respond to voice theapy Injection Laryngoplasty Vocal fold augmentation Hoarseness is an early symptom Most common site of disease in laryngeal cancer is the vocal folds Treated with surgery and/or radiation Glottic Cancer Post treatment voice therapy beneficial to maximize best prossible vocal production Involuntary spasms of the muscles of the larynx Thought to be a central motor processing disorder of the basal ganglia Types of SD Abductor Adductor Mixed Treatment: Botox Adjunt to Botox Voice therapy Spasmodic Dysphonia 18

19 Muscle Tension Dysphonia Increased muscular tension of the intrinsic musculature Whisper or high pitched vocal quality Extrinsic muscular tension may be present Voice therapy Laryngeal manual therapy Circumlaryngeal therapy Resonant Voice therapy Humming, etc Treatment for Muscle Tension Dysphonia Voice therapy primary treatment Combine with myofascial laryngeal release can accelerate outcome and shorten the course of treatment Myofascial release is a manual technique to work on areas of laryngeal muscle resistance from least to greatest. References Andrianopoulos, M., Gallivan, G., Gallivan, H. PVCM, PVCD, EPL, and Irritable Larynx Syndrome: What are we talking about and how do we treat it? J Voice. 2000;14: Angsuwaransee, T, Morrison, M. Extrinsic laryngeal muscular tension in patients with voice disorders. J Voice; 200;16: Bach, K.K., Belafsky, P.C., Wasylik, K., Postma, G.N., Koufman, J.A. Validity and Reliability of the Glottal Function Index,, Archives of Otolaryngology Head and Neck Surgery, 131, , Belafsky, P.C., Postma, G.N., Koufman, J.A. Validity and Reliability of the Reflux Symptom Index (RSI), Journal of Voice, 16, , Blaugrund, et al Effects of lateral manual compression upon glottic incompetence: objectives evaluations. Ann Otol Rhino Laryngol, 99(4 pt 1), , Ferrand, C.T. Voice Disorders (2012). Boston, MA:Pearson Jacobson, B.H., Johnson, A., Grywalski, C., Silbergleit, A., Jacobson, G., Benninger, The Voice Handicap Index (VHI): Development and Validation, American Journal of Speech Language Pathology, Vol 6(3), 66 70, Koufman, J., Stern, J, Bauer, M. Dropping Acid: The Reflux Diet Cookbook and Cure (2010). 19

20 McColl, D., Hooper, A., VonBerg, S. Contemporary Issues in Communication Sciences and Disorders. 2006;13: Morrison, M, Rammage, L, Emami, A. The irritable larynx syndrome. J Voice. 1999; 13: Morrison, M., Rammage, L. The irritable larynx syndrome as a central sensitivity syndrome. Canadian Journal of Speech Language Pathology and Audiology. 2010;34 (4): Pimentel, J.T., Peregoy, B.M.(2012). Applied Anatomy & Physiology for Speech Language Pathology & Audiology. Philadelphia, PA: Wolters Kluwer Lippincott Williams & Wilkins Schindler, A., Bottero, A., Capaccio, P., Ginocchio, D., Adorni, F., Ottaviani, F. Vocal Improvement after voice therapy in unilateral vocal fold paralysis. J Voice. 2008; 22: Wang, C.P., Ko, J.Y., Wang, Y.H., Hu, Y.L., Hsiao, T.Y. Vocal process granuloma A result of long term observation in 53 patients. Oral Oncology, 2009;4,: Zraick, R.I., Kempster, G.B., Connor, N.P., Thibeault, S., Klaben, B.K., Bursac, Z., Thrush, C.R., Glaze, L.E. Establishing Validity of the Consensus Auditory Perceptual Evaluation of Voice (CAPE V), American Journal of Speech Language Pathology, 20(1), 14 22,

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