WHAT ARE THE FACTS? The use of JUUL s and other electronic cigarettes and their impact on preconception health in NC
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1 WHAT ARE THE FACTS? The use of JUUL s and other electronic cigarettes and their impact on preconception health in NC October 17 th, 2018
2 Disclosures None of today s presenters have any actual, potential or perceived conflicts of interest related to the contents of this webinar
3 Acknowledgements This training was developed by the March of Dimes North Carolina Preconception Health Campaign, under a contract and in collaboration with the North Carolina Division of Public Health, Women s Health Branch. Many thanks to Megan Canady, Center for Maternal and Infant Health at UNC-CH, and Jim Martin, NC Tobacco Prevention and Control Branch Thanks to Wake AHEC for their support in providing continuing education credit for this webinar
4 Housekeeping Obtaining credits Groups viewing together should Asking questions Accessing resources at a later date Credits and evaluation
5 CREDITS Nursing: 1.5 Contact Hours Wake AHEC, Nursing Education, is an approved provider of Continuing nursing education by the North Carolina Nurses Association, an accredited approver by the American Nurses Credentialing Center s Commission on Accreditation. Wake AHEC CEU: Wake AHEC will provide 0.2 CEU to participants upon completion of this activity. National Association of Social Workers (NASW) NC AHEC is a 2018 NASW-NC approved provider of distance continuing education. This program has been approved for 1.5 contact hours A participant must attend 100% of the webinar to receive credit. Partial session credit will not be awarded. Contact Hours: Wake AHEC will provide up to 1.5 Contact Hours to participants. Wake AHEC is part of the North Carolina AHEC Program.
6 Objectives Learn about various tobacco products, with a focus on new electronic cigarettes, such as JUUL, and other emerging electronic nicotine delivery devices. Understand the health impact of e-cigarettes and secondhand aerosol on youth and pregnant women and describe successful tobacco use prevention initiatives. Increase knowledge of the health risks of tobacco and nicotine use in the preconception period and learn the importance of cessation efforts prior to pregnancy. Participants will learn about ENDS use among reproductive age women in North Carolina and the 5As and 5Rs for screening and counseling. Participants will learn about FDA-approved pharmacotherapy for adults, and their use by pregnant and lactating women.
7 What Are the Facts? The Use of JUUL s and Other Electronic Cigarettes and Their Impact on Preconception Health in North Carolina March of Dimes North Carolina Jim D. Martin, MS, Director of Policy and Programs N.C. Tobacco Prevention and Control Division of Public Health October 17, 2018
8 The Burden of Tobacco Use in North Carolina 1 in 5 Deaths in NC due to tobacco use Smoking costs North Carolina $3.81 billion per year in health care costs Including $931 million in Medicaid costs For every death, 30 sick or disabled There is an additional annual cost of $293 million from health problems due to secondhand smoke
9 90% of tobacco users start before the age of 18
10 Youth Cigarette smoking is decreasing and was largely unchanged from PERCENTAGE OF STUDENTS Cigarette Use in Past 30 Days, NC YTS High School Middle School NORTH CAROLINA YOUTH TOBACCO SURVEY RESULTS
11 Changing Landscape of Tobacco Products
12 Overall youth tobacco use was relatively steady from PERCENTAGE OF STUDENTS 45 Use of Any Tobacco Product in Past 30 Days, NC YTS High School Middle School NORTH CAROLINA YOUTH TOBACCO SURVEY RESULTS 2017 North Carolina Youth Tobacco Survey Results
13 Between Current Youth Use of E-Cigarettes Increased: 430% Middle School 894% High School In 2017 more students said they were considering using e-cigarettes in the next year than currently used them Percentage of Students 25 Current E-Cigarette Use and Potential Future Use, NC YTS : Considering Middle School High School Use Next Year NORTH C2017 NORTH CAROLINA YOUTH TOBACCO SURVEY RESULTS AROLINA YOUTH TOBACCO SURVEY RESULTS
14 E-cigarettes are still the #1 product used by youth Use of Tobacco Products in Past 30 Days, NC YTS 2017 E-cigarettes Cigars/cigarillos/little cigars Middle School High School Cigarettes Chewing tobacco/snuff/dip Hookah Roll-your-own cigarettes Snus Percentage of Students 2017 NORTH CAROLINA YOUTH TOBACCO SURVEY RESULTS
15 10% of women who recently had a baby used e-cigarettes in the past 2 years % Use of e-cigarettes in the past 2 years among women who have recently had a baby NC PRAMS, % % 7.6% 5.4% 7.3% Total Less than 25 years old years old Age 35 or over High school education > High school
16 Of women who used e-cigarettes in past 2 years 64% used during 3 months before pregnancy Use during 3 months before pregnancy 36.3% 18% used during last 3 months of pregnancy Use during last 3 months of pregnancy 82.3% More than once a day Once a day 2-6 days a week 1 day a week or less Did not use e-cigarettes Source: NC Prams 2016
17 USB-Shaped E-cigarettes
18 (Stanford University Research into the Impact of Tobacco Advertising, 2018)
19 JUUL and Other E-cigarettes Market Growth and Concern IN MARCH, 2018, JUUL REPRESENTED 54.6% DOLLAR SHARE OF THE E-CIGARETTE TRADITIONAL RETAIL MARKET. ON APRIL 24 TH, THE FDA REQUESTED THAT JUUL LABS, INC. SUBMIT DOCUMENTS RELATING TO MARKETING PRACTICES AND RESEARCH ON MARKETING, EFFECTS OF PRODUCT DESIGN, PUBLIC HEALTH IMPACT, AND ADVERSE EXPERIENCES AND COMPLAINTS RELATED TO JUUL. Source: Nielsen Total US xaoc/convenience Database and Wells Fargo Securities, LLC
20 JUULpods and Flavors The product has 5 flavors in pods for the JUUL. These pre-filled JUULpods are sold in the following flavors: Fruit Medley, Virginia Tobacco, Cool Mint, or Crème Brulee, and Mango Each pre-filled pod is equal to about 1 pack of cigarettes. Some reviews of the product suggest about 200 puffs. The JUULpods contain 0.7 ml of e liquid with a very high level of nicotine; 59mg/ml or 5% nicotine by weight.
21 JUUL Nicotine Delivery 59 mg/ml This graph from PAX Labs shows the rate at which nicotine is absorbed and stays in a test subject s blood.
22 Public Health Concerns The concentration of nicotine in JUUL is more than double the concentration found in other e-cigarettes. othis high concentration is a serious concern for youth, who are already uniquely susceptible to nicotine addiction. The addictive potential is so high that the US Surgeon General has declared that youth use of nicotine in any form is unsafe. Educators report that youth are using e-cigarettes on our tobaccofree high school campuses
23 Nicotine Poses Unique Dangers to the Developing Human Nicotine is toxic to developing fetuses and impairs fetal brain and lung development Nicotine use while adolescent brain is developing can disrupt brain circuit formation Poisonings occur among users via ingestion of nicotine liquid, absorption through skin, and inhalation Source: England, Lucinda J et al. Nicotine and the developing human: A neglected element in the electronic cigarette debate. Am Journ Prev Med 2015.
24 Among Youth, E-cigarette Use May Lead to Conventional Cigarette Use U.S. adolescents and young adults who had never smoked, but used e- cigarettes at baseline, were 8.3 times more likely to progress to cigarette smoking after 1 year than nonusers of e-cigarettes. Source: US Surgeon General Report, 2016
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26 FDA Actions Related to JUUL and Other E- cigarettes
27 Source: California Department of Health,
28 Prevention is Critical Successful multicomponent programs prevent young people from starting to use tobacco in the first place and more than pay for themselves in lives and health care dollars saved. Source: US Department of Health and Human Services. 50 Years of Progress: A Report of the Surgeon General, Available at:
29 High School Current Tobacco Use (%) State Spending on Tobacco Prevention and Cessation ($ in millions) High School Tobacco Use and State Spending on Tobacco Use Prevention and Cessation in North Carolina NC Tobacco free Schools Movement begins 2000 $17.1 $17.1 $17.1 $18.3 $18.3 $ Tobacco Master Settlement Funding for Tobacco begins in NC via HWTF 2002 $0.0 $ % $6.2 $10.9 $15.0 $ % 26.6% 25.8% 25.8% 29.7% $ % $1.2 $1.2 $ High School Current Tobacco Use NC Schools 100% Tobacco free 2008 Emergence of e-cigarette use among youth 2011 State Spending on Tobacco Prevention and Cessation In , appropriations for cessation only 28.8 In 2017, $500k non-recurring for tobacco use prevention Since 2001, North Carolina has received an average of $149,825,874 per year from the Tobacco Master Settlement Agreement $
30 Performance Measures : Effective tobacco use prevention messages Education of and organizational involvement of adults who influence youth such as parents, teachers, staff and faculty, health and mental health professionals Number of smoke-free/tobacco free policies, including e-cigarettes, adopted by local governments, colleges, housing, and workplaces Compliance with tobacco-free schools law, tobacco-free child care center rules and tobacco-free college campuses Collaborative efforts to reduce youth access to tobacco products Collaborative efforts to address tobacco use prevention in schools through the Whole Child, Whole School, Whole Community model
31 QuitlineNC Pregnancy Protocol Woman-centered 10 coaching sessions 7 calls days of enrollment 1 call 30 days prior to due date 2 postpartum calls (15 days & 45 days) Relapse prevention sensitivity Structured content for those not ready to quit
32 2 Karen Caldwell David Willard Northampton Camden Alleghany Rockingham Gates Currituck Ashe Surry Warren Stokes Caswell Person Vance Hertford Pasquotank Halifax Mitchell Watauga Wilkes Granville Perquimans Yadkin Forsyth Orange Avery Guilford Franklin Bertie Chowan Yancey Caldwell Alexander Davie Alamance Durham Nash Madison Edgecombe Washington Burke Iredell Martin Dare Buncombe Davidson Wake Tyrrell Tyrell Haywood McDowell Catawba Randolph Chatham Wilson Swain Rowan Pitt Beaufort Graham Rutherford Lincoln Johnston Hyde Jackson Henderson Lee Greene Cabarrus Gaston Stanly Moore Harnett Cherokee Macon Transylvania Polk Cleveland Wayne Lenoir Montgomery Craven Clay Mecklenburg Pamlico Cumberland Union Anson Richmond Sampson Jones Hoke Duplin Scotland Carteret Onslow Robeson Bladen Pender 1 Tobin Lee tobin@mountainwise.org Tobacco Prevention and Control Branch (TPCB) Funds Regions Carleen Crawford Carleen.Crawford@mecklenburgcountync.gov 5 Mary Gillett David.Willard@apphealth.com Catherine.Mulvihill@wakegov.com mgillett@myguilford.com Lead Counties 6 Ashley Curtice acurtice@co.cumberland.nc.us 7 Michelle Mulvihill Columbus Brunswick New Hanover 9 Vacant 10 Allyson Moser allyson.moser@pittcountync.gov 1. Macon County Public Health 2. Rutherford-Polk-McDowell District Health Department 3. Appalachian District Health Department 4. Mecklenburg County Health Department 5. Guilford County Department of Health and Human Services, Public Health Division 6. Cumberland County Public Health Department 7. Wake County Human Services 8. Robeson County Department of Public Health 9. Albemarle Regional Health Services 10. Pitt County Health Department 8 Ernest Watts ernest.watts@hth.co.robeson.nc.us Local Tobacco Coordinators Durham County Health Department Natalie Rich, nrich@dconc.gov Orange County Health Department April Richard, arichard@orangecountync.gov Mecklenburg County Health Department - Kim Bayha, Kimberly.bayha@mecklenburgcountync.gov
33 For Further Information Contact: Sally Herndon, MPH Branch Head (919) Jim Martin, MS Director of Policy and Programs (919) Jennifer Park, MPH Director of Local Program Development and Regulations (919) Ann Staples, MA Director of Communication and Education (704) Joyce Swetlick, MPH Director of Tobacco Cessation (919) Steph Gans, LCAS, LCSWA, CTTS Tobacco Treatment Specialist (919)
34 Why is preconception health so important? We now know that ONE-HALF of all infant mortality and morbidity are DIRECTLY RELATED to the health of the mother BEFORE she became pregnant!
35 Preconception care is Opportunistic Preconception care is for every woman of childbearing age (14-44) every time she is seen Every woman, every time = an opportunity for you to convey important health messages She may not be pregnant this time, but could be the next time you see her Pregnancy Info.net (2018). Childbearing. What are Child Bearing Years? Retrieved from
36 Preconception Health: Reproductive Life Planning #1 on the CDC s list of preconception health recommendations is to encourage all men & women of childbearing age to have a reproductive life plan (RLP) #1 goal of an RLP is to reduce unintended pregnancies (47%) and to allow the opportunity to modify risky health behaviors prior to conception Johnson K et al, Recommendations to Improve Preconception Health and Health Care-United States A Report of the CDC/ATSDR Preconception Care Work Group and the Select Panel on Preconception Care, MMWR Reports and Recommendations, April 21,
37 Why are unintended pregnancies a concern? Increased risk for infant morbidity and mortality; including premature birth, low birthweight, and birth defects Increased elective abortion rate Late entry into prenatal care Lack of Mental Health treatment/counseling Higher rates of smoking prior to pregnancy Increased risk of physical abuse and partner relationship ending for mothers Increased child abuse and neglect Increased Medicaid costs Guttmacher Institute (2016). Fact Sheet. Unintended Pregnancy in the United States.
38 Increased infant morbidity and mortality Adverse health conditions Obesity Fetal and neonatal death Neural tube defects Large baby Increased risk for obesity in child Hypertension Pre-term birth Placental abnormalities Birth defects from medications Low birth weight Women with unintended pregnancies may be more likely to have pre-existing medical conditions that adversely affect birth outcomes Poor mental health Sexually Transmitted Infections Diabetes Pre-term birth Low birth weight Miscarriage/Still birth Pre-term birth Birth defects Macrosomia STI Transmission to infant Low birth weight Miscarriage/Still birth Eye infections or blindness Preterm birth Pneumonia Asthma Pre-term birth Low birth weight Small for gestational age Adapted from California Preconception Care Provider training, County of Los Angeles, Department of Public Health, 2003
39 Increased infant morbidity and mortality Risky health behaviors Tobacco use Low birth weight Small for gestational age Pre-term delivery SIDS Still birth Women who have unintended pregnancies may be more likely to engage in behaviors that negatively impact birth outcomes Alcohol use Preterm birth Birth defects Mental retardation Stillbirth Miscarriage Illicit drug use Fetal death Brain injuries Pre-term birth Developmental problems Birth defects Kost, K., & Lindberg, L. (2015). Pregnancy Intentions, Maternal Behaviors, and Infant Health: Investigating Relationships With New Measures and Propensity Score Analysis. Demography, 52(1),
40 Desired outcomes: Preconception healthcare that includes tobacco cessation counseling Healthier women and more intended pregnancies Healthier pregnancies and better birth outcomes
41 Asdf
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43 EveryWomanNC.org
44 Keys to success Rapport building Motivational counseling Progress toward behavior change Goal setting Diane Pearson, Dulce Program, San Diego Family Care
45 You Quit, Two Quit: Tobacco Cessation For Women of Reproductive Age Megan Canady, MSPH, MSW Center for Maternal and Infant Health The University of North Carolina at Chapel Hill 2018 You Quit, Two Quit YouQuitTwoQuit.org
46 You Quit Two Quit FREE Onsite Training YouQuitTwoQuit.org
47 Electronic Nicotine Delivery Systems & Perinatal Health YouQuitTwoQuit.org
48 ENDS & Reproductive Age Women The health effects of using e-cigarettes & other ENDS before or during pregnancy have not been adequately studied Nicotine is a known reproductive toxicant and has adverse effects on fetal development, including lung and brain development The use of smokeless tobacco products, such as snus, during pregnancy has been associated with preterm delivery, stillbirth, and infant apnea Research suggests that women perceive ENDS to be less harmful and less stigmatizing than cigarette use during pregnancy CDC; England, et al. 2016; Mark, et al YouQuitTwoQuit.org
49 ENDS & Poison Control Exposures to e-cigarettes & liquid nicotine can be fatal for infants and young children Even a teaspoon of liquid nicotine can be fatal; smaller amounts can cause severe illness E-cigarette Device & Liquid Nicotine Reported Exposures to Poison Centers YouQuitTwoQuit.org
50 ENDS Aerosol E-cigarette aerosol is NOT harmless water vapor The CDC has stated that air containing ENDS aerosol is less safe than clean air ENDS use has the potential to involuntarily expose children adolescents, pregnant women, and non-users to aerosolized nicotine, toxic substances and, if the products are altered, to other psychoactive substances. Clean air free of both smoke and ENDS aerosol remains the standard to protect health. YouQuitTwoQuit.org
51 Tobacco Use and Women of Reproductive Age YouQuitTwoQuit.org
52 Percentage Women & Tobacco Use in NC, 2016 Current Smoker Ever used ENDS NC State Center for Health Statistics. Available from: YouQuitTwoQuit.org
53 North Carolina Pregnancy Risk Assessment Monitoring System (PRAMS) Survey Results, Asked only of mothers who reported using e-cigarettes or other electronic nicotine products in the past 2 years. 2 Use caution in interpreting cell sizes less than YouQuitTwoQuit.org
54 Tobacco Use During Pregnancy in NC 1 in 10 babies in NC are born to women reporting tobacco use during pregnancy In some counties over 30% of babies are born to women who smoked YouQuitTwoQuit.org
55 Tobacco use during pregnancy is directly associated with the top causes of infant mortality in NC YouQuitTwoQuit.org
56 Tobacco Use Causes Poor Birth & Infant Outcomes Maternal/Fetal Harm From Tobacco Infant/Child Harm From Tobacco o o o o o o o Infertility Miscarriage Ectopic Pregnancy Premature Birth Low Birth Weight Stillbirth SIDS o o o o o SIDS Ear infections Respiratory Infections Asthma Links with childhood obesity, cancer, & attention disorders, and cardiovascular disease & diabetes in adulthood YouQuitTwoQuit.org
57 Behavior Change & the 5As/5Rs YouQuitTwoQuit.org
58 The 5 As: Evidence-Based, Best Practice Intervention ASK the patient about her tobacco use status ADVISE her to quit tobacco with personalized messages ASSESS her willingness to quit in next 30 days ASSIST with (pregnancy- and parent-specific, if applicable) self-help materials & social support ARRANGE to follow-up during subsequent visits YouQuitTwoQuit.org
59 Step 1: Ask 1 Minute Ask your clients: Which of the following statements best describes your *cigarette smoking? A. I have NEVER smoked, or I have smoked less than 100 cigarettes in my lifetime. B. I stopped smoking OVER a year ago. C. I stopped smoking LESS THAN a year ago. D. I smoke, but not every day. E. I smoke daily. * 5As and the Ask was validated referring to cigarette smoking Fiore, et al. 2008; Melvin CL, et al YouQuitTwoQuit.org
60 Step 1: Ask 1 Minute (Pregnant) Ask your pregnant clients: Which of the following statements best describes your cigarette smoking? A. I have NEVER smoked, or I have smoked less than 100 cigarettes in my lifetime. B. I stopped smoking BEFORE I found out I was pregnant, and I am not smoking now. C. I stopped smoking AFTER I found out I was pregnant, and I am not smoking now. D. I smoke some now, but have cut down on the number of cigarettes I smoke since I found out I was pregnant. E. I smoke regularly now, about the same as I did before I found out I was pregnant. Fiore, et al. 2008; Melvin CL, et al YouQuitTwoQuit.org
61 Step 1: Ask 1 Minute (Postpartum) Ask your postpartum clients: Which of the following statements best describes your cigarette smoking? A. I have NEVER smoked, or I have smoked less than 100 cigarettes in my lifetime. B. I stopped smoking BEFORE I found out I was pregnant, and I am not smoking now. C. I stopped smoking AFTER I found out I was pregnant, and I am not smoking now. D. I stopped smoking during pregnancy, but I am smoking now. E. I smoked during pregnancy, and I am smoking now. Fiore, et al. 2008; Melvin CL, et al YouQuitTwoQuit.org
62 Screen for Other Tobacco Products Please circle any of the following tobacco products you have used in the past month: Electronic Cigarettes (Juul) Chew Snus Strips Sticks Orbs Lozenges Hookah Cigars/Cigarillos YouQuitTwoQuit.org
63 Examples of Other Tobacco Products Hookah E-cigarettes and vaping products YouQuitTwoQuit.org
64 Screen for Second-Hand Exposure Questions for Adults: 1) Does anyone smoke (or vape) in your home? 2) Does anyone smoke (or vape) in your car? 3) Is smoking (or vaping) allowed in your workplace? Questions for Parents/ Caretakers of Children: 1)Does the mother smoke(or vape)? If yes, in the home? In the car? 2) Does the father smoke (or vape)? If yes, in the home? In the car? 3) Is the child exposed to tobacco smoke (or vape) on a regular basis (at least once a week) by anyone other than the parents? Fiore, et al. 2008; Melvin CL, et al YouQuitTwoQuit.org
65 Step 2: Advise 1 Minute Clear, strong, personalized advice to quit Clear: My best advice for you and your baby is for you to quit using tobacco. Strong: Quitting tobacco is one of the most important things you can do to protect your baby and your own health. Personalized: Impact of tobacco use on the baby, the family, and the patient s well being YouQuitTwoQuit.org
66 Step 3: Assess 1 Minute Assess the patient s willingness to quit within the next 30 days. If a patient responds that she would like to try to quit within the next 30 days, move on to the Assist step. If the patient does not want to try to quit, use the 5 Rs to try to increase her motivation. YouQuitTwoQuit.org
67 Step 4: Assist 3+ Minutes Suggest and encourage the use of problem-solving methods and skills for tobacco cessation Provide social support as part of the treatment Arrange social support in the patient s environment Provide (pregnancy- and parent-specific, if applicable) self-help tobacco cessation materials Provide a proactive fax referral to the Quitline YouQuitTwoQuit.org
68 QuitlineNC Perinatal-Specific Services Includes Services for ENDS Use Specialized services for pregnant and postpartum women: Up to 10 calls with relapse prevention sensitivity. One call delivered 30 days prior to due date 2 postpartum contacts (15 & 45 days postpartum) for women who quit Structured content for pregnant tobacco users not ready to quit Specialized services for teens YouQuitTwoQuit.org
69 Step 5: Arrange 1+ Minute Follow up to monitor progress and provide support Encourage the patient Express willingness to help Ask about concerns or difficulties Invite her to talk about her success YouQuitTwoQuit.org
70 Employ the 5 Rs RELEVANCE: Help patient figure out the relevant reasons to quit, based on their health, environment, individual situation RISKS: Encourage patient to identify possible negative outcomes to continuing to use tobacco REWARDS: Encourage patient to identify possible benefits to quitting ROADBLOCKS: Work with patient to identify obstacles to quitting and potentially how to overcome them REPETITION: Address the 5Rs with patients at each visit Fiore, et al YouQuitTwoQuit.org
71 Pharmacotherapy to Quit Tobacco YouQuitTwoQuit.org
72 Public Health Service Guidelines ENDS are NOT an FDA approved means to quit tobacco use Non-pregnant adults are more likely to quit when using a combination of brief counseling and pharmacotherapy Behavioral intervention is first-line treatment in pregnant women o Pharmacotherapy has not been sufficiently tested for efficacy or safety in pregnant patients o May be necessary for heavy tobacco users Fiore, et al. 2008; USPSTF, 2015 YouQuitTwoQuit.org
73 FDA-Approved Pharmacotherapies for Adults Nicotine Replacement Products All forms of NRT are Pregnancy Category D Nicotine Patch Nicotine Gum Lozenge Nicotine Nasal Spray Nicotine Inhaler Non-Nicotine Prescription Medications Bupropion SR (Pregnancy Category C) Varenicline (Pregnancy Category C) YouQuitTwoQuit.org
74 Nicotine Replacement During Lactation Lactation Risk Category: L2 Limited Data Compatible Nicotine Patch (non-prescription) Constant dose 21 mg transdermal patch results in nicotine equivalent to smoking 17 cigarettes daily passing into breastmilk 7mg & 14mg patches result in proportionately lower amounts in breastmilk Nicotine Gum/Lozenge (non-prescription) Amount of nicotine that passes into breastmilk is variable, depending on the amount chewed/dissolved Nicotine Inhaler (prescription only) Maternal plasma concentrations are about 1/3 of those of smokers, so breastmilk concentrations are probably proportionately less as well LACTMED; Hale, YouQuitTwoQuit.org
75 Bupropion and Varenicline During Lactation Bupropion Lactation risk category: L3 Limited Data Probably Compatible AAP: Drugs whose effect on nursing infants is unknown but may be of concern Peak milk level occurs 2 hrs. after a 100mg dose this milk level provides 0.66% of the maternal dose Anecdotal reports of reduction in milk supply after beginning bupropion Should not be used in mothers and infants prone to seizures Varenicline Lactation risk category: L4 No Data - Possibly Hazardous AAP: Not reviewed Very little information available There are concerns about its long half-life (24 hrs.) In animal studies, the drug was transferred to nursing pups LACTMED; Hale, YouQuitTwoQuit.org
76 Tools for Providers, Clinics, & Patients YouQuitTwoQuit.org
77 YouQuitTwoQuit.org YouQuitTwoQuit.org YouQuitTwoQuit.org
78 78 Perinatal Patient Education Materials: Booklets (English and Spanish) YouQuitTwoQuit.org
79 Perinatal Patient Education Materials: Handouts (English & Spanish) YouQuitTwoQuit.org
80 Perinatal Patient Education Materials: Handouts (English & Spanish) YouQuitTwoQuit.org
81 Provider 5As/5Rs Pocket Card YouQuitTwoQuit.org
82 Ordering Materials Order these FREE resources by going to this link and click the Publications Form. Look at the end of page 3 under Tobacco Cessation and fax in your order. YouQuitTwoQuit.org
83 YQ2Q Practice Bulletin Includes the following resources: 5As algorithm Evidence-based screening questions How to make a proactive referral to QuitlineNC Billing for cessation counseling Rx during pregnancy & lactation E-cigarette info Trauma-informed tobacco care YouQuitTwoQuit.org
84 Perinatal Patient Education Materials: Posters (English & Spanish) YouQuitTwoQuit.org
85 References 85 Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health. Information for Health Care Providers and Public Health Professionals: Preventing Tobacco Use During Pregnancy. Available from: Chamberlain, C., O'Mara-Eves, A., Oliver, S., Caird, J. R., Perlen, S. M., Eades, S. J., & Thomas, J. (2013). Psychosocial interventions for supporting women to stop smoking in pregnancy. Cochrane Database Syst Rev, 10, CD doi: / cd pub4 Coleman, T., Chamberlain, C., Davey, M. A., Cooper, S. E., & Leonardi-Bee, J. (2015). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev, 12, CD doi: / cd pub2 Curtin, S.C., Matthews, T.J. (2016). Smoking prevalence and cessation before and during pregnancy: data from the birth certificate, National Vital Statistics Report, 65, England LJ, Tong VT, Koblitz A, Kish-Doto J, Lynch MM, Southwell BG. (2016). Perceptions of emerging tobacco products and nicotine replacement therapy among pregnant women and women planning a pregnancy. Prev Med Rep Dec; 4: Fiore, M.C., Jaen C.R., Baker, T.B., Bailey, W. C., Benowitz, N. L., Curry, S. J., Wewers, M. E. (2008). Treating tobacco use and dependence: 2008 update - clinical practice guidelines. Rockville, MD: U.S. Department of Health and Human Services, PublicHealth Service, Agency for Healthcare Research and Quality. Hale T. Medications and Mothers Milk Hale Publishing, Haug NA, Stitzer ML, Svikis DS. Smoking during pregnancy and intention to quit: a profile of methadone-maintained women. Nicotine & Tobacco Research. November 1, ;3(4): Jones HE, Heil S, O'Grady K, et al. Smoking in pregnant women screened for an opioid agonist medication study compared to related pregnant and non-pregnant patient samples. The American journal of drug and alcohol abuse. 2009;35(5): Jones HE, Heil SH, Tuten M, Chisolm MS, Foster JM, O'Grady KE, Kaltenbach K. Cigarette smoking in opioid-dependent pregnant women: neonatal and maternal outcomes. Drug Alcohol Depend. 2013; 131(3): LACTMED: Drug and Lactation Database. National Institutes of Health. Nicotine.. Available from: Mark KS, Farquhar B, Chisolm MS, Coleman-Cowger VH, Terplan M. Knowledge, Attitudes, and Practice of Electronic Cigarette Use Among Pregnant Women. J Addict Med Jul- Aug;9(4): Melvin CL, Dolan-Mullen P, Windsor RA, Whiteside HP Jr, Goldenberg RL.. Recommended cessation counselling for pregnant women who smoke: A review of the evidence. Tob Contr, Suppl 3:III80-4. YouQuitTwoQuit.org
86 References, cont. 86 N.C. State Center for Health Statistics, Hospital Discharge Data, Quinn G, Ellison BB, Meade C, Roach CN, Lopez E, Albrecht T, Brandon TH. Adapting smoking relapse-prevention materials for pregnant and postpartum women: formative research. Matern Child Health J May;10(3): Ripley-Moffatt CE, et al. Safe Babies: A Qualitative Analysis of the Determinants of Postpartum Smoke-Free and Relapse States. Nicotine Tob Res. 2008; 10(8): Su, A., Buttenheim, A.M. (2014). Maintenance of smoking cessation in the postpartum period: which interventions work best in the long-term? Matern Child Health J, 18, Tong, V. T., Dietz, P. M., Morrow, B., D'Angelo, D. V., Farr, S. L., Rockhill, K. M. (2013). Trends in smoking before, during, and after pregnancy--pregnancy Risk Assessment Monitoring System, United States, 40 sites, MMWR Surveill Summ, 62(6), Tong, V.T., Jones, J.R., Dietz, P.M., D Angelo, D., Bombard, J.M. (2009). Trends in smoking before, during, and after pregnancy pregnancy risk assessment monitoring system (PRAMS), United States, 31 sites, MMWR, 58, Winklbaur B, Baewert A, Jagsch R, Rohrmeister K, Metz V, Aeschbach Jachmann C, Thau K, Fischer G. Association between prenatal tobacco exposure and outcome of neonates born to opioid-maintained mothers. Implications for treatment. Eur Addict Res. 2009; 15(3): U.S. Department of Health and Human Services, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health (Ed.). The health consequences of smoking - 50 years of progress: a report of the Surgeon General US Preventive Service s Task Force. Tobacco Smoking Cessation in Adults, Including Pregnant Women: Behavioral and Pharmacotherapy Interventions. Sept Available from: WHO. (2013). World Health Organization (WHO) Recommendations for the Prevention and Management of Tobacco Use and Second-Hand Smoke Exposure in Pregnancy. Retrieved from YouQuitTwoQuit.org
87 Postpartum Relapse Nearly 2/3 of women who quit smoking during pregnancy relapse within one year Postpartum smoking relapse rates may be as high as 80%, and of those who relapse: 45% resume smoking at two to three months, and up to 60-70% by six months Relapse may be delayed or avoided among women who receive smoking cessation counseling during the postpartum period McBride CM et al. Prevention of relapse in women who quit smoking during pregnancy. Am J Public Health 1999;89: Smoking during pregnancy United States, MMWR Morb Mortal Wkly Rep. 2004;53(39):911 5: Scheibmeir M, O'Connell KA. In harm's way: childbearing women and nicotine. J Obstet Gynecol Neonatal Nurs. 1997;26: ; Ershoff DH, Quinn VP, Mullen PD. Relapse prevention among women who stop smoking early in pregnancy: a randomized clinical trial of a self-help intervention. Am J Prev Med. 1995;11:
88 Preventing Postpartum Relapse Good documentation Use the 5 A s at the postpartum visit Use positive language to counsel Reiterate messages of: Risks to babies and children from smoke and vape exposure Make your home a TOBACCO-FREE ZONE Praise for efforts to quit and stay quit for the individual
89 Treating Postpartum Relapse Reassure and encourage her to try again Review Triggers Refer back to QuitlineNC and self help materials Ensure patient has a medical home
90
91 March of Dimes North Carolina Preconception Health Campaign A statewide initiative aimed at improving birth outcomes in NC by reaching out to women with important health messages before they become pregnant Formerly functioned as the NC Folic Acid Campaign Goals of the Campaign are to reduce infant mortality, birth defects, premature birth, and chronic health conditions in women, while also aiming to increase intended pregnancies in NC Seeks to raise awareness and inspire positive action among the general public, health care professionals, and community agencies
92 Questions? Comments?
93 Thank you! Brenda W. Stubbs Jennifer Vickery Triad Region Coordinator Western Region Coordinator For more information about the Campaign and other preconception health topics visit: EveryWomanNC.org and at Latinasana.org Follow us on Facebook and
94
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