11/17/2013. Dr. Kumar Sandrasegaran Dr. Curtis Wright Beth Ward. Increased utilization of medical imaging:
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1 Bilal Tahir, MD Gitasree Borthakur, MD Indiana University School of Medicine Department of Radiology & Imaging Sciences Dr. Kumar Sandrasegaran Dr. Curtis Wright Beth Ward November 15, 2013 ACP 2013 Increased utilization of medical imaging: introduction of new technologies (PET, MRA, CTA, etc.) new uses for existing technologies self-referral patient demand defensive medicine Number of CT Scans Performed Annually Diagnostic Imaging has a growth rate of 8-16% annually Estimated over 10 percent of these exams are not necessary or are duplicative Over 1 billion radiology exams annually. The overall cost of diagnostic imaging is estimated over $100 billion annually in the United States alone. According to the ACP, all unnecessary tests cost $200-$250 billion a year. 0 20,000,000 40,000,000 60,000,000 80,000,000 Landro L. Radiation risks prompt push to curb CT scans. The Wall Street Journal. Mar Sherman D. Stemming the tide of overtreatment in U.S. healthcare. Reuters. Feb
2 Some providers boost utilization to pay off imaging technology investments Physicians who own their own imaging equipment are 2-7 times more likely to order an imaging test. Physicians face increasing patient demands for specific diagnostic imaging tests. A survey of 7,7320 patients and 300 physicians indicates that patients were more satisfied with physicians who used a participatory style of discussion options (Annals of Internal Medicine). Kouri BE, Parson RG. Physician self-referral for diagnostic imaging: review of the empiric literature. American Journal of Roentgenology. 2002;179: Kaplan S H, Greenfield S, Gandek B, Rogers W H, Ware J E J. Characteristics of physicians with participatory decision-making styles Annals of Internal Medicine. 1996;124(5): Physicians worry about malpractice lawsuits The Mount Sinai School of Medicine conducted a survey of 2,416 physicians, which showed 91% of physicians believe that concerns over malpractice lawsuits result in defensive medicine. Estimated cost is $60 billion annually % of tests, procedures, referral and consultations were ordered to avoid lawsuits Education on appropriate use of imaging Patients Physicians Health care system administrators Radiologists need to open doors of communication with ordering clinicians Vast majority of physicians practice 'defensive medicine' according to physician survey. Science Daily. Mount Sinai School of Medicine. July ACR Appropriateness Criteria Evidence-based guidelines to assist referring physicians and other providers in making the most appropriate imaging or treatment decision for a specific clinical condition. 186 topics with over 900 variants in the February 2013 version. Can be integrated with computerized ordering and electronic health record (EHR) systems. Healthcare organizations can ensure that the right patient gets the right scan for the right indication
3 Do I need imaging to answer question? Does a prior imaging study already answer question? What imaging study do I need? What general imaging protocol to order? Is this really the best imaging study for THIS patient? Contraindications? Have I used the tools at my disposable to clarify any confusion? Routine ICU chest x-rays Routine pre-operative chest x-rays Incidental pulmonary nodules Headache Low back pain Incidental thyroid nodules Incidental adrenal nodules Renal cysts Ovarian cysts Non-contrast vs contrast vs both CT Meta-analysis of eight trials comprising 7,078 ICU patients, half of whom received daily chest and the other half who received chest radiographs for specific clinical indication. Eliminating routine daily chest radiographs did not affect mortality, length of stay in the hospital or ICU, or ventilator days in either group. Oba Y, Zaza T. Abandoning daily routine daily chest radiography in the intensive care unit: meta-analysis. Radiology 2010; 255 (2): Hejblum G. Comparison of routine and ondemand prescription of chest radiographs in mechanically ventilated adults: a multicentre, cluster-randomised, two-period crossover study. The Lancet. Nov Routine daily chest radiographs are not indicated. Follow up radiographs should be obtained only for specific clinical indications (increasing hypoxia, initial line or tube placement, etc.) Morosa JK. Expert Panel on Thoracic Imaging. ACR Appropriateness Criteria routine chest radiographs in ICU patients. American College of Radiology (ACR);
4 Methodist Hospital: 140 ICU beds Wishard Hospital: 24 ICU beds, 29 PICU beds St. Vincent: 40 ICU beds, 16 Trauma/NICU beds. Community Hospital North: 24 ICU beds Community Hospital East: 12 ICU beds Chest Xray: $42 (est. payment from insurance) Healthcare Blue Book 2013 Systematic review of 14 published articles No association between preop CXR and morbidity or mortality Postoperative pulmonary complications in those with preop CXR was 13% vs 16% in those without Acute cardiopulmonary disease is suspected on the basis of history and physical exam. History of stable chronic cardiopulmonary disease in a patient > 70 years old without a chest radiograph within the past 6 months. Joo HS, Wong J, Naik VN, Savoldelli GL. The value of screening preoperative chest x-rays: a systematic review. Can J Anaesth 2005; 52(6): Mohammed T. et al. Routine admission and preop chest radiography. ACR Appropriateness Criteria
5 Rounded opacity <3 cm without other lung abnormalities. Benign pattern of calcification or stability of nodule size for over 2 years for solid pulmonary nodules CT Chest without contrast: $312 CT Chest with contrast: $396 (est. payment from insurance) Healthcare Blue Book
6 19 yo woman presents to PCP office Frontal headache for 1 day Onset at rest, pressure-like pain Studying for finals this week Similar symptoms every few months What is the next appropriate step? A) CT head without contrast B) MRI head without contrast C) MRA head and neck D) EEG E) Patient reassurance Chronic headache, no new features: None Chronic headache, new features: MRI head without +/- with IV contrast Sudden onset severe headache: CT head without contrast Sudden onset unilateral headache, ipsilateral Horner s syndrome, suspected carotid/vertebral dissection: CTA or MRA head and neck Suspected complication of sinusitis: CT paranasal sinuses without IV contrast CT head without contrast: $340 CT head with and without contrast: $676 MRI head without contrast: $660 MRI head without and with contrast: $779 (est. payment from insurance) 36 year old male with increasing low back pain x 10 days No trauma No fevers, chills, neurological deficit Past medical history unremarkable Healthcare Blue Book
7 Next step A) Pain management and physical therapy B) X-ray lumbar spine C) CT lumbar spine D) MRI lumbar spine E) Fluoroscopic myelogram 56-year-old male. Low back pain especially on left side for 6 weeks. History of prostate cancer. Next step: A) X-ray lumbar spine B) CT lumbar spine C) MR lumbar spine D) Pain management and physical therapy 7
8 Imaging considered if no improvement within 6 weeks Or red flags: Cauda equina syndrome Cancer- insidious onset, weight loss Fracture- age >50, osteoporosis, cumulative trauma Neurologic deficit Symptomatic spinal stenosis Infection- IV drug use, immunosuppression, diabetes Indications for IV contrast: Cancer Infection Prior surgery Reassess if GFR <35 X-ray lumbar spine: $200-$300 CT lumbar spine: $549 MRI lumbar spine: $780 (est. payment from insurance*) 5% thyroid nodules are malignant. On CT, thyroid nodules with size > 1 cm, calcifications, or septations should be further evaluated for malignancy with US. Risk factors: age <15 or >60, male sex, history of head/neck radiation, family history Healthcare Blue Book 2013 Ahmed S. Incidental Thyroid Nodules on Chest CT: Review of the Literature and Management Suggestions. American Journal of Roentgenology. Nov Thyroid calcification with possible soft tissue, US evaluation confirmed benign parenchymal calcification Dense calcification 8
9 Thyroid Nodule, over 1 cm, calcifications. US evaluation with biopsy = cancer Heterogenous thyroid nodule, Ca ++, > 1 cm Neck Ultrasound: $113 (est. payment from insurance) Healthcare Blue Book 2013 Up to 5% of thoracic and abdominal CT may reveal an adrenal incidentaloma 83% are non functioning benign lesions Differentiate benign from mass that warrants treatment (metastasis, pheochromocytoma, adrenal carcinoma) Sahdev A. The Indeterminate Adrenal Lesion. Cancer Imaging. 18 March
10 Less than 1 cm, ignore Stable 6 12 months = benign <10 HU = benign <4cm nodule without known malignancy <0.2% likelihood of malignancy 1-4 cm may be followed up in 1 year > 4 cm biopsy, surgery, or PET-CT 10
11 Abdomen CT without contrast: $314 Abdomen CT with contrast: $398 Abdomen CT with and without contrast: $465 Abdomen and Pelvis without contrast: $393 Abdomen and Pelvis with contrast: $618 Abdomen and Pelvis with and without contrast: $782 (est. payment from insurance*) Healthcare Blue Book 2013 Simple cyst (Bosniak Type I) imperceptible wall rounded Work up: none 11
12 Mildly complex (Bosniak type 2) Thin septa Thin calcification Work up: none Simple or hemorrhagic cysts < 5 cm No follow-up Simple cysts 5-7 cm Annual US follow up to ensure lesion stability Hemorrhagic cysts 5-7 cm 6 12-week follow-up US to ensure resolution Simple cysts > 7 cm Further imaging (e.g., MRI) or surgery Levine D. et al. Management of asymptomatic ovarian and other adnexal cysts Imaged at US. Society of Radiologists in Ultrasound Consensus Conference Statement. Ultrasound Quarterly 2010;26: Simple cysts < 1 cm No follow-up Simple cysts 1 7 cm mention on report Annual US After 2 years or if size i a longer interval follow up Simple cysts > 7 cm as in premenopausal women 12
13 Aortic dissection Adrenal mass workup (may only need noncontrast) Renal mass workup HCC follow-up status post non-surgical treatment AAA status post endovascular stent graft repair CT Urogram CT Cystogram Metastatic cancer work-up / follow-up Trauma (head & C/T/L-spine without) Abdominal / pelvic / chest pain, weight loss, infection, inflammatory processes, most other indications For artery evaluation, CTA Some indications require multiple post contrast phases (HCC screening dual or triple phase, pancreatic dual phase) Gastrografin --- if pt < 150 lbs, recent GI surgery/enteric leak Water --- pancreatic protocol Volumen --- enterography 13
14 59 year old man with history of heroin abuse complaining of excruciating chest pain radiating to his back. HTN- medication non-compliance, presenting with BP of 214/110. Prior ischemic stroke without current neurological deficits, diabetes mellitus. EKG and Chest X-ray are normal. Next step? A) CTA Chest with IV contrast B) CT Chest without IV contrast, CTA chest with IV contrast C) CT Chest with IV contrast D) MRI Chest without and with IV contrast E) CT Chest without IV contrast F) No imaging 65 yo AAM on hemodialysis, needs imaging for renal mass work-up. Order what? 14
15 63 year old man with history of alcohol abuse, hepatitis C, elevated AFP What is the next imaging modality to order? A) Abdominal ultrasound B) MRI abdomen without contrast C) CT abdomen single phase D) CT abdomen triple phase E) MRI abdomen without and with IV contrast A) US guided core biopsy B) Abdomen MRI without & with IV contrast C) Abdomen Ultrasound D) No further imaging to confirm diagnosis E) CT guided FNA & core biopsy 15
16 Adrenal mass in recent immigrant from Burma. 65 yo man s/p endovascular stent graft repair for AAA. No acute symptoms. Presents for AAA stent graft evaluation. Calcifications Type II endoleak Ask if imaging is really needed? Use radiologist as a consultant rather than lab service. Radiologists can add value to patient care and help eliminate extra imaging, costs and anxiety. Eliminate routine ICU chest x-rays, only post procedure or specific indications Eliminate preoperative chest x-rays in patients without cardiopulmonary disease 16
17 For incidental pulmonary nodules, follow Fleishner society guidelines. Ignore 4 mm pulmonary nodules in low risk patients. Chronic headaches without new features generally do not need imaging. Most low back pain without red flags will respond to conservative management without imaging intervention. Incidental adrenal nodules under 1 cm can be ignored. Those 1-4 cm may be followed up in 1 year. Incidental thyroid nodules on CT can usually be ignored if under 1 cm without calcifications or septations. Most renal cysts are simple or mildly complex (thin septa or calcification) and require no further imaging. For simple or hemorrhagic ovarian cysts under 5 cm in premenopausal women, no follow-up. Simple ovarian cysts under 1 cm in postmenopausal women can be ignored. Avoid unnecessary CT precontrast or postcontrast phases when possible. Some indications require precontrast and postcontrast imaging to avoid repeat imaging. If confused or uncertain, call or radiology colleagues 1. Aagaard E, Maselli J, Gonzales R. Physician practice patterns: chest x-ray ordering for the evaluation of acute cough illness in adults. Med Decis Making 2006; 26(6): Ahmed S. Horton KM. Jeffrey RB. Sheth S. Fishman E. Incidental Thyroid Nodules on Chest CT: Review of the Literature and Management Suggestions. American Journal of Roentgenology. Nov Volume 195. Number Basi SK, Marrie TJ, Huang JQ, Majumdar SR. Patients admitted to hospital with suspected pneumonia and normal chest radiographs: epidemiology, microbiology, and outcomes. Am J Med 2004; 117(5): Coursey CA, Nelson RC, Patel MB, et al. Making the diagnosis of acute appendicitis: do more preoperative CT scans mean fewer negative appendectomies? A 10-year study. Radiology (2): Daffner RH, Weissman BN, Wippold FJ II, Angtuaco EJ, Appel M, Berger KL, Cornelius RS, Douglas AC, Fries IB, Hayes CW, Holly L, Mechtler LL, Prall JA, Rubin DA, Ward RJ, Waxman AD, Expert Panels on Musculoskeletal and Neurologic Imaging. ACR Appropriateness Criteria suspected spine trauma. [online publication]. Reston (VA): American College of Radiology (ACR); p. [87 references] 7. De Hert S, Imberger G, Carlisle J. The value of screening preoperative chest x-rays: a systematic review. June/July 2005, Volume 52, Issue 6, pp Kaplan S H, Greenfield S, Gandek B, Rogers W H, Ware J E J. Characteristics of Physicians with Participatory Decision-Making Styles Annals of Intern Medicine. 1996;124(5): Kouri BE, Parson RG. Physician Self-Referral for Diagnostic Imaging: Review of the Empiric Literature. American Journal of Roentgenology. 2002;179: Landro L. Radiation Risks Prompt Push to Curb CT Scans. The Wall Street Journal. Mar Macmahon H et al. Guidelines for Management of Small Pulmonary Nodules Detected on CT Scans: A Statement from Fleishner Society. Radiology 2005.; 237: Morosa JK, Bramwit MP, Mohammed TL, Reddy GP, Brown K, Dyer DS, Ginsburg ME, Heitkamp DE, Jeudy J, Kirsch J, MacMahon H, Ravenel JG, Saleh AG, Shah RD. Expert Panel on Thoracic Imaging. ACR Appropriateness Criteria routine chest radiographs in ICU patients. American College of Radiology (ACR); Niess M. Preoperative Chest Xrays: A Teachable Moment. JAMA Intern Med. Sep Rao PM, Rhea JT, Novelline RA, Mostafavi AA, McCabe CJ. Effect of computed tomography of the appendix on treatment of patients and use of hospital resources. N Engl J Med 1998;338(3): Sahdev A. Willatt J. Francis I. Reznek RH. The indeterminate adrenal lesion. Cancer Imaging. 18 March (1): Sherman D. Stemming the tide of overtreatment in U.S. healthcare. Reuters. Feb Schwartz. Prevalence and Importance of Small Hepatic Lesions Found at CT in Patients with Cancer. January Radiology Vast majority of physicians practice 'defensive medicine,' according to physician survey. ScienceDaily. Mount Sinai School of Medicine. July van Randen A, Bipat S, Zwinderman AH, Ubbink DT, Stoker J, Boermeester MA. Acute appendicitis: metaanalysis of diagnostic performance of CT and graded compression US related to prevalence of disease. Radiology 2008; 249(1): WB, Jr. Abdominal CT scanning in reproductive-age women with right lower quadrant abdominal pain: does its use reduce negative appendectomy rates and healthcare costs? Am Surg 2007;73(6):
18 Please feel free to with questions: Look forward to speaking on similar/other topics in future. 18
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