HEADACHE. Dr Nick Pendleton. September Headache
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1 HEADACHE Dr Nick Pendleton September 2017 Headache Tension Type Headache Cranial Nerve Examination Migraine Migraine Treatment Medication Overuse Headache Headache Red Flags Sinusitis Headache Raised ICP Headache Acute Severe Headache 1
2 Small Group Work Tension Type Headache Cranial Nerve Examination Migraine Migraine Treatment Medication Overuse Headache Headache Red Flags Sinusitis Headache Raised ICP Headache Acute Severe Headache NICE GUIDELINE CG150 Diagnosis and Management of Headaches in Young People and Adults (last updated Nov 2015) 2
3 NICE HEADACHE PATHWAY pathways/headaches 3
4 NICE CKS HEADACHE ASSESSMENT he-assessment#!scenario 4
5 British Association for the Study of Headache 5
6 (A)At least 10 episodes fulfilling the criteria B-D: (B) Headache lasting from 30 minutes to 7 days (C) Headache has at least two of the following characteristics: Bilateral location Pressing/tightening (non-pulsating) quality Mild or moderate intensity Not aggravated by routine physical activity such as walking or climbing stairs (D) Both of the following: No nausea or vomiting (anorexia may occur) No more than one episode of photophobia or phonophobia (E) Not attributable to another disorder Patient with Tension-Type Headache indicating location of his headache pain by British Medical Journal Publishing Group Loder E, Rizzoli P BMJ 2008;336:
7 Infrequent episodic tension-type headache Diagnosed if headaches meeting the above criteria occur <1 day a month (<12 days a year) on average Frequent episodic tension-type headache Diagnosed if headaches occur >1 and <15 days a month (>12 and <180 days a year). Chronic tension-type headache Diagnosed if headaches occur 15 days a month (180 or more days a year). 7
8 RED FLAGS Onset of new or different headache Nausea or vomiting Worst headache ever experienced Progressive visual or neurological changes Paralysis Weakness, ataxia or loss of coordination Drowsiness, confusion, memory impairment or loss of consciousness Onset of headache after age of 50 years More RED FLAGS Symptoms/Signs of Papilloedema Stiff neck Onset of headache with exertion, sexual activity or coughing Systemic illness Numbness Asymmetry of pupillary response Sensory loss Signs of meningeal irritation 8
9 Link to Article about Red Flags 9
10 10
11 11
12 MIGRAINE Migraine Repeated attacks of headache lasting 4 72 hours that have these features : A: Normal physical examination B: No other reasonable cause for the headache C: At least two of: Unilateral pain Throbbing pain, Aggravation of pain by movement, Moderate or severe intensity of pain D: At least one of Nausea or Vomiting Photophobia and phonophobia 12
13 MIGRAINE WITH AURA 20 30% experience migraine with aura Focal neurological phenomena that precede the attack Appear gradually over 5 to 20 minutes and generally last fewer than 60 minutes Headache phase usually begins within 60 minutes of the end of the aura phase. AURA Common aura symptoms include: Visual disturbances (such as flashing/flickering lights, zigzag lines and even temporary blindness) Numbness, tingling sensations and slurred speech. Other aura symptoms include a stiff neck, weakness on one side, partial paralysis, confusion or fainting 13
14 Migraine, Stroke and the OCP Patients who have Migraine with Aura are at increased risk of ischaemic stroke Giving these patients an OCP increases this risk significantly + Hypertension + Smoking + age > 35 In Women under 35: Some figures: those who do not have migraine and do not take the pill (i.e. the background risk): 1.3 per 100,000 women per year are at risk of stroke those who have migraine without aura but don t take the pill: 4 per 100,000 women per year at risk of stroke those who have migraine with aura but don t take the pill: 8 per 100,000 women per year are at risk of stroke those who don t have migraine and take the pill: 5 per 100,000 women per year at risk of stroke those who have migraine with aura and take the pill: 28 per 100,000 women per year at risk of stroke those who have migraine without aura and take the pill: 14 per 100,000 women per year are a risk of stroke 14
15 UKMEC 2016 UK medical eligibility criteria for contraceptive use (UKMEC) guideline urological-conditions Eg. Migraine with Aura at any age Combined Pill use: Cat 4. Unacceptable Risk Treatments for Migraine Triptans, selective 5-HT 1B/1D receptor agonists various formulations & types Ergot derivatives (older treatment, not commonly used) Antiemetics & nsaids Preventative : 2/3 will have 50% reduction Many have significant side effects: Pizotifen weight gain, drowsiness B- Blockers tiredness Tricyclics drowsiness Anticonvulsants valproate, topiramate, gapapentin significant s/e. Botulinum Toxin type A Candesartan : 15
16 Medication Overuse Headache Headache present on at least 15 days per month Developed or markedly worsened during medication overuse Headache resolves or reverts to its previous pattern within two months on discontinuation Regular overuse for three months or more 16
17 Culprits Opiates, codeine +/- paracetamol 10 days+ per month Triptans or NSAIDs 15 days+ per month Vicious Cycle Bad spell of headaches eg stress Take more painkillers Body gets used to medication Rebound/withdrawal if stop for>1d Think this is another usual headache Take more painkillers Problem worsens 17
18 Blood Pressure and Headache Very High BP can cause Headache Patients will Expect to have BP checked when presenting with Headache Children with Headache check BP 3rd Trimester Pregnancy and Headache?Pre-eclampsia SINUSITIS HEADACHE Headache worse on lying down Nasal congestion Nasal discharge purulent +/- blood Cough, Fever, Malaise Tender at point of pain Can be unilateral Treatment: 18
19 RAISED ICP New increasing headache Present on waking Increased by stooping or straining Changes in mental state Vomiting Papilloedema Causes: sinister and benign, acute and chronic Idiopathic Intracranial Hypertension Link to Excellent summary: 19
20 SAH Risk factors similar to stroke eg. Smoking, hypertension Family History in 5-20% Incidence 6 cases per 100,000 patient yrs 50% fatality, 1/3 remain dependent Sudden explosive headache is the cardinal feature. If related to sexual intercourse?sah CT scanning is mandatory in all, to be followed by (delayed) lumbar puncture if CT is negative 20
21 SAH A period of unresponsiveness of >1 h occurs in almost half of patients Focal signs develop at the same time as the headache or soon afterwards in one third of patients Classically, the headache from aneurysmal rupture develops in seconds, but can be minutes SAH Vomiting occurs in 70% of patients Neck stiffness is a common sign in SAH of any cause, but takes hours to develop and therefore cannot be used to exclude the diagnosis if a patient is seen soon after the sudden-onset headache If thunderclap headache is the only symptom then 10% only will have SAH, but all need investigation 21
22 Consultation Analysis A Patient with a Headache JULIE JONES, 45 TELEPHONE TRIAGE CONSULTATION (Dr A) Headache: started 3 days ago gradual onset worse last night Started to feel nauseous with it yesterday Analgesia does help Global but more at front left Slight dizziness with nausea no vomiting or visual disturbance of gross neurological symptoms Suggested comes in for examination but most likely tension type headache Fictional name and age for illustration 22
23 JULIE JONES, 45 FY2 CONSULTATION IN SURGERY (same day) 3/7 tension like headache, frontal. No photophobia Vomited 3x overnight Very stressed with work Had tension and migraines in the past Helped when lying down Not worse bending over No visual symptoms JULIE JONES, 45 Unlikely to be pregnant - partner has had vasectomy. D/W Dr B Ibuprofen and paracetamol helped marginally o/e PEARL, no focal tenderness, appears anxious Discussed stress at work and sleep hygiene Advised to return if problem persists or deteriorates 23
24 JULIE JONES, 45 DISCHARGE LETTER Hosp to ITU (1 week later) Collapsed that evening and had seizure Intubated and ventilated Platelet count 6 Discussed with Haematology Diagnosis TTP To Have Plasma Exchange in Liverpool JULIE JONES, 45 Edited Highlights: Had 3 cardiac arrests, Had plasma exchange Discharged after 3 weeks Medication started: Phenytoin, Prednisolone, Aspirin, Gliclazide Haematology follow up, Platelet count recovered Steroids reduced, gliclazide stopped Driving: notify DVLA. Cannot drive for 6 months 24
25 LEARNING POINTS? NEXT SESSION 3rd October Patients with Suspected Cancer Symptoms (Dr Nick Pendleton) 25
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