Subject Index. dermatitis herpetiformis 11 DNA repair 2l3-215 Duncan's disease and EBV 55

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1 Subject Index acquired immunodeficiency syndrome (AIDS) association with other lesions HPV infections necrotising stomatitis 120 salivary gland diseases 120, 121 ulcerations 118 candidiasis 99-lO4 erythematous loo, lo 1 pseudomembranous lol-lo4 classification 98, 99 diagnosis 98 hairy leukoplakia lo4-lo7 Kaposi's sarcoma lo7-112 non-hodgkin's-lymphoma periodontal diseases prognosis 98 adult rhabdomyoma and EBV 56 AgNOR 154, 155 ano-genital infections of HPV 66 antral carcinoma and EBV 56 aphthae 43,47,57,62,63 and Behect's syndrome 62,63 and EBV 57 and HSV 43 and VZV 47 argyrophilic nucleolar organisation region proteins (AgNOR) 154, 155 B cell lymphomas Behcet's syndrome and aphthae and HCMV 62,63 bcl-2-oncogenes 232, 233 bone marrow transplantation and HCMV 59 bromodeoxyuridine labelling 151 Burkitt's lymphoma 52, l34-l36 and EBV 52 candidiasis and HIV carcinoma 40, 42, 56, 62, 70, 73, 154, 155, , genomic instability head and neck 54,155, microsatellite instability 214 mismatch repair 2l3,214 nasopharyngeal and EBV 56 nasopharyngeal and HPV 73 oncogenes oral 40,42,56,62 proliferation markers spindle cell and HPV 73 squamous cell, see squamous cell carcinoma verrucous and HPV 70 cell proliferation markers chromosomes , l , common wart (verruca vulgaris) and HPV 68 condyloma acuminatum and HPV 67,68 cytogenetic analysis in squamous cell carcinoma 202, 203 dermatitis herpetiformis 11 DNA repair 2l3-215 Duncan's disease and EBV 55 EBV Duncan's disease 55 hairy cell leukemia 55 hairy leukoplakia Hodgkin's disease 54 lymphomatoid granulomatosis 55 lymphoproliferative diseases mid-line granuloma 54 nasopharyngeal carcinoma 56 non-hodgkin's lymphoma 54 salivary gland tumours 56 Sjogren's syndrome 55 thymic lymphoma 55

2 242 epidermal growth factor (EGF) epidermolysis bullosa cell-matrix-interaction 13 classification of hereditary types 12 oral manifestations of inherited forms 13 pathogenesis 13, 14 Epstein-Barr virus (EBV) erythema multiforme 14-19,41 etiology 17 histopathological features 17 HSV infection 18,41 pathogenesis 17, 18 extranodal non-hodgkin's lymphoma fibroplastic growth factor (FGF) 226 flow cytometry 155, 156 focal epithelial hyperplasia and HPV 68 gastro-intestinal and oral ulceration and HCMV genomic instability in head and neck cancer graft versus host disease and HCMV 63 growth factor and growth factor receptorrelated genes guanosine triphosphate binding oncogenes hairy cell leukaemia and EBV 55 hairy leukoplakia and EBV and HIV HCMV Behcet's syndrome 62, 63 bone marrow transplantation 59 gastro-intestinal ulceration 60, 61 graft versus host disease 63 HIV 60 Kaposi's sarcoma 61,62 oral carcinoma 62 oral ulceration 60, 61 organ transplantation 59, 60 salivary gland diseases 62 head and neck cancer, genomic instability herpes simplex viruses, see HSV herpes varicella zoster virus HIV 60,99-116, 120, 121, candidiasis HCMV 60 hairy leukoplakia Kaposi's sarcoma linear gingival erythema 114 lymphomas necrotising gingivitis necrotising periodontitis 116 non-hodgkin's-lymphoma Subject Index periodontal diseases salivary gland diseases 120, 121 HPV 65-73, ano-genital infection 66 common wart (verruca vulgaris) 68 condyloma acuminatum 67, 68 focal epithelial hyperplasia 68 HIV infection keratoses 70 leukoplakia 70 lichen planus 69 nasopharyngeal carcinoma 73 oral infection 66, 67 spindle cell carcinoma 73 squamous cell carcinoma 70 squamous cell papilloma 67 verucous carcinoma 70 warty lesions 68, 69 Hodgkin's disease and EBV 54 HSV 18,34,35,41-43 aphthae 43 erythema multiforme 18,41 keratoses 42 lichen planus 42 oral carcinoma 42, 43 subtypes 1 and 2 34, 35 human cytomegalovirus, see HCMV human herpesvirus 6 63, human immunodeficiency virus, see HIV human papillomavirus infection, see HPV 65-73, immunohistochemical methods of cell proliferation jaw lesions and proliferation markers 167 Kaposi's sarcoma 61,62,64, and HCMV 61, 62 and HIV human herpesvirus-8 64 keratoses and HSV 42 Ki leukoplakia and proliferation markers lichen planus 19-23,42,69, 164, 165 expression ofhla-dr and ICAM-l 23 histopathological features 21, 22 HPV 69 HSV 42 pathogenic mechanisms 22, 23 proliferation markers 164, 165 linear gingival erythema and HIV 114

3 Subject Index linear immunoglobulin A bullous dermatosis 10, 11 lymphomas 52,54,55, , association with HIV B-cell Burkitt's 52, classification 126, 127 extranodal non-hodgkin's Hodgkin's 54 MALT non-hodgkin's plasma cell tumours salivary gland including MALT staging 128 thymic and EBV 55 T cell Waldeyer's ring 133, 134 lymphomatoid granulomatosis and EBV 55 lymphoproliferative diseases and EBV MALT lymphoma, see lymphomas MIB-1 antibodies 152 microsatellite instability in sporadic cancers 214 mid-line granuloma and EBV 54 mismatch repair and familial cancer 213, 214 mitotic counts 149 mucocutaneous conditions affecting the mouth 1-24 mucous membrane pemphigoid 6-10 antibodies against hemidesmosomeassociated proteins 10 binding ofig to basement membrane zone (BMZ) 8 histopathological features 8, 9 pathogenesis 9, 10 myc oncogenes nasofacial T cell lymphoma nasopharyngeal carcinoma 56, 73 EBV 56 HPV 73 necrotising (ulcerative) gingivitis and HIV necrotising (ulcerative) periodontitis and HIV 116 necrotising stomatitis 120 non-hodgkin's lymphoma and HIV and EBV 54 oncogenes , bcl epidermal growth factor (EGF) 225, 226 receptor (EGFR) fibroblastic growth factor (FGF) 226 interaction with cell proliferation myc oncogenes oral carcinoma protein kinases (abl, fes, mos, raf) ras-oncogenes transforming growth factor-alpha (TGF-a) 226 v-erb-b-protein 228 oral carcinoma 42,43,47, 56, 62 EBV 56 HCMV 62 HSV 42,43 VZV 47 oral infections of HPV 66, 67 oral leukoplakia (keratosis) and HPV 70 oral viral diseases 32-73, EBV HCMV HIV HSV HPV 32-34,65-72 VZV oral warty lesions and HPV 68, 69 organ transplantation and HCMV 59, p53 protein , ,237 analysis of its protein 181, 182 biomarker 188, 189 diagnostic applications 189, 190 oral tumours pleomorphic adenoma 193 prognostic significance risk factors for oral cancers 183, 184 salivary gland carcinoma 193, 194 squamous cell carcinoma , tumourigenesis tumour suppressor genes ,237 papillomaviruses, see HPV pemphigus vulgaris 2-6 auto-antibodies to desmoglein-1 5 histopathological features 3, 4 pathogenesis 5 pemphigus vulgaris antigen (PV A) 5 periodontal diseases and HIV plasma cell tumours prognosis and proliferation markers 161, 162 proliferating cell nuclear antigen (PCNA) 153, 154 proliferation markers argyrophilic nucleolar organisator regions (AgNOR) 154, 155 bromodeoxyuridine labelling 151

4 244 Proliferation markers (Contd.) cancer cell proliferation 138 clinical applications comparison of methods 156, 157 flow cytometry 155, 156 immunohistochemical methos interactions oncogenes tumour suppressor genes jaw lesions 167 Ki leukoplakia lichen planus MIB-1 and MIB-3 antibodies 152 mitotic counts 149 prognosis proliferatung cell nuclear antigen (PCNA) salivary gland tumours S-phase indices 149 thymidine labelling 149, 150 protein kinases and other oncogenes protein p53, see p53 protein ras-gene family Reye's syndrome 44 S-phase indices 149 salivary gland disease and HCMV 62 salivary gland tumours 56, 165 and EBV 56 and proliferation markers 165 Sjogren's syndrome and EBV 55 Subject Index spindle cell carcinoma and HPV 73 squamous cell carcinoma 70, , , allelic imbalance 201 allotype analysis 211 chromosomes cytogenetic analysis 202, 203 HPV 70 micro satellite instability p53 protein , target regions squamous cell papilloma and HPV 67 Stevens-Johnson syndrome 14 suppressor protein p53, see p53 protein target regions in squamous cell carcinoma thymic lymphoma and EBV 55 thymidine labelling transforming growth factor-alpha (TGF-a) 226 tumour suppressor genes, see p53 protein ,233 ulcerations not otherwise specified 118 varicella (chickenpox) 44,45 v-erb-b-protein 228 verucous carcinoma and HPV 70 viral infections, see oral viral diseases VZV (varicella zoster virus) 47 zoster (shingles) 45-47

5 Index of Volumes Current Topics in Pathology Volume 87: Recent Progress in Atherosclerosis Research. Edited by E. VOLLMER and A. ROESSNER N. SIMIONESCU, A. SIMA, A. DOBRIAN, D. TIRZIU, and M. SIMIONESCU, Pathobiochemical Changes of the Arterial Wall at the Inception of Atherosclerosis K. SUEISHI, M. KUMAMOTO, H. SAKUDA, and K. TANAKA, Angiogenic Processes in the Pathogenesis of Human Coronary Atherosclerosis A. ROESSNER, E. VOLLMER, E. JAEGER, J. RAUTERBERG, and W. BOCKER, Differentiation and Role of Macrophages in the Early Human Atherosclerotic Plaque H. ROBENEK and N. J. SEVERS, Lipoprotein Receptors on Macrophages and Smooth Muscle Cells E. VOLLMER and A. ROESSNER, In Situ Localization and Distribution Pattern of Apolipoproteins in Arterial Walls: A Comparative Study in Atherosclerosis and Renal Transplant Arteriopathy J. RAUTERBERG, E. JAEGER, and M. ALTHAUS, Collagens in Atherosclerotic Vessel Wall Lesions H. HEINLE, D. KLING, and E. BETZ, Metabolism of Fibromuscular and Atheromatous Plaques in an Experimental Model: Causal Mechanisms for the Development of Intimal Necrosis E. VOLLMER and A. ROESSNER, Parallels Between Renal Transplant Arteriopathy and Atherosclerosis in Respect of Functional Morphology Volume 88: Tubulointerstitial and Cystic Disease of the Kidney. Edited by S. DODD P. D. WILSON and D. FALKENSTEIN, The Pathology of Human Renal Cystic Disease S. DODD, The Pathogenesis of Tubulointerstitial Disease and Mechanisms of Fibrosis G. WOLF and E. G. NEILSON, Cellular Biology of Tubulointerstitial Growth R. SINNIAH and T. N. KHAN, Morphometric Assessment of Tubulointerstitial Damage in Renal Disease B. IVANYI and S. OLSEN, Tubulitis in Renal Disease N. MARCUSSEN, Atubular Glomeruli in Chronic Renal Disease F. N. ZIYADEH and S. GOLDFARB, The Diabetic Renal Tubulointerstitium H.-J. GRONE, Selected Experimental Models of Renal Tubular Atrophy and of Cystic Tubular Cell Hyperplasia J. A. ROBERTS, Mechanisms of Renal Damage in Chronic Pyelonephritis (Reflux Nephropathy)

6 Volume 89: Soft Tissue Thmors. Edited by D. HARMS and D. SCHMIDT H. HASHIMOTO, Incidence of Soft Tissue Sarcomas in Adults J. TREUNER and M. MORGAN, Clinical Management of Soft Tissue Sarcomas D. HARMS, Soft Tissue Sarcomas in the Kiel Pediatric Tumor Registry T. J. TRICHE, Molecular Biological Aspects of Soft Tissue Tumors C. TURC-CAREL, F. PEDEUTOUR, and E. DURIEUX, Characteristic Chromosome Abnormalities and Karyotype Profiles in Soft Tissue Tumors W. MELLIN, A. NIEZABITOWSKI, M. BROCKMANN, J. RITTER, P. WUISMAN, and V. KRIEG, DNA Ploidy in Soft Tissue Tumors: An Evaluation of the Prognostic Implications in the Different Tumor Types D. KATENKAMP and H. KOSMEHL, Heterogeneity in Malignant Soft Tissue Thmors P. MEISTER, Grading of Soft Tissue Sarcomas: Proposal for a Reproducible, Albeit Limited Scheme D. SCHMIDT, Fibrous Tumors and Tumor-like Lesions of Childhood: Diagnosis, Differential Diagnosis, and Prognosis P. MEISTER, Malignant Fibrous Histiocytoma: A "Fibrohistiocytic" or Primitive, Fibroblastic Sarcoma P. W. ALLEN, Recent Advances in Tumors of Adipose Tissue W.A. NEWTON, JR., Classification of Rhabdomyosarcoma I. LEUSCHNER, Spindle Cell Rhabdomyosarcoma: Histologic Variant of Embryonal Rhabdomyosarcoma with Association to Favorable Prognosis D. HARMS, Alveolar Rhabdomyosarcoma: A Prognostically Unfavorable Rhabdomyosarcoma Type and Its Necessary Distinction from Embryonal Rhabdomyosarcoma D. SCHMIDT, Malignant Peripheral Neuroectodermal Tumor A. O. CAVAZZANA, V. NINFO, R. TIRABOSCO, A. MONTALDI, and R. FRUN ZIO, Leiomyosarcoma C. D. M. FLETCHER, Malignant Peripheral Nerve Sheath Tumors C. D. M. FLETCHER, Rare Soft Tissue Sarcomas

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