E. Staging a WHO (World Health Organization) b TNM (Tumor Node Metastasis)
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1 I KNOWLEDGE LIST ONCOLOGY Knowledge of neoplasms in animals (dog, cat, pocket pets, horses, cows) A. Clinical signs, History, Physical Exam (PE) B. Work up 1. Diagnostic Imaging a Bone Scan b Thyroid Scan c Computed Tomography (CT) d Magnetic Resonance Imaging (MRI) e Positron Emission Tomography (PET) f Chest X-Ray (CXR) g Abdominal X-Ray (AXR) h Abdominal Ultrasound (AUS) i Thoracic Ultrasound j Echocardiology k Radiographs l Contrast radiography 2. Diagnostic Tests a Immunocytochemistries b Immunohistochemistries c Cytology d Histopathology e CBC f Chemistry profile g Urinalysis h Electrophoresis i Serum IgA quantitation 3. Diagnostic Procedures a Biopsy principles b Bone Marrow Aspirate c Fine needle aspirate (FNA) C. Treatment options and goals of each a Surgery (cryotherapy, hyperthermia, photodynamic therapy) b Radiation Therapy (brachytherapy, tomotherapy) c Chemotherapy (administration and safety major goal) d Biological response modification e Combinations of above D. Prognosis E. Staging a WHO (World Health Organization) b TNM (Tumor Node Metastasis) II Knowledge of Tumor classifications A. Terminology: tumor vs neoplasm B. Differentiate tumor biology between species, breeds C. Causes and pathophysiology D. Pathology, cytology, histologic class - 1 -
2 E. Pseudoneoplasms: lick granuloma F. Differentiate between benign tumors and malignant tumors G. Tumor biology, origins 1. Mesenchymal 2. Epithelial 3. Round cell 4. Melanoma H. Tumor names (listed alphabetically) 1. Acanthomatous epulis 2. Adenocarcinoma (ADC) 3. Adenoma 4. Astrocytoma 5. Basal cell 6. B-cell insulin-secreting 7. Bile duct ADC 8. Bronchogenic CA 9. Canine Lymphoma Lymphoid Leukemia 10. Canine myeloproliferative disorders and malignant histiocytosis 11. Carcinoma (CA) 12. Carcinomatosis 13. Ceruminous gland ADC 14. Chemodectoma 15. Chondrosarcoma (ChSA) 16. Ependymoma 17. Feline Lymphoma and Leukemia 18. Feline retrovirus 19. Fibroma 20. Fibrosarcoma (FSA) 21. Glioma 22. Granulomatous meningioencephalitis (GME) 23. Hemangiopericytoma (HPC) 24. Hemangiosarcoma (HSA) 25. Histiocytoma 26. Hyperplasia 27. Infiltrative lipoma 28. Insulinoma 29. Leiomyoma 30. Leiomyosarcoma 31. Leydig cell 32. Lipoma 33. Liposarcoma (LipoSA) 34. Lymphangiosarcoma 35. Lymphoma (canine and feline) 36. Malignant fibrous histiocytoma 37. Melanoma 38. Mast Cell Tumor (MCT ) 39. Meningioma 40. Multiple myeloma 41. Myeloproliferative disorders - 2 -
3 42. Myoblastoma 43. Myxosarcoma 44. Neurofibroma 45. Neurofibrosarcoma (NFSA) 46. Osteosarcoma (OSA) 47. Papilloma 48. Perianal adenoma 49. Perianal gland ADC 50. Peripheral Nerve Sheath Tumor (PNST) 51. Pheochromocytoma 52. Pilomatricoma 53. Pituitary CA 54. Plasmacytoma 55. Pulmonary CA 56. Rhabdomyosarcoma 57. Schwannoma 58. Sebaceous adenoma 59. Sebacious gland ADC 60. Seminoma 61. Sertoli cell tumor 62. Soft Tissue Sarcoma (STS) 63. Spindle cell SA 64. Squamous Cell Carcinoma (SCC) 65. Squamous metaplasia 66. Sweat gland (Apocrine gland) CA 67. Synovial cell SA 68. Thymoma 69. Thyroid CA 70. Transitional Cell Carcinoma (TCC) 71. Transmissible Venereal Tumor (TVT) 72. Trichoblastoma 73. Trichoepithelioma 74. Undifferentiated CA 75. Undifferentiated SA III Knowledge of Chemotherapy A. Chemotherapeutic classes and mechanism of action, including nadirs B. Chemotherapy agents and protocols C. Side effects and adverse reactions of chemotherapy, treatment options D. Safe handling and disposal of chemotherapeutic agents E. Administration techniques of chemotherapeutic agents F. Ability to utilize multiple body measurement systems G. Rescue protocols H. Chemoprotectants I. Chemo resistance J. Alkylating agents K. Antitumor antibiotics L. Platnimum drugs M. Enzymes - 3 -
4 N. Mitotic inhibitors O. Emergency extravasation protocols P. Ability to recognize cancer remission status IV Knowledge of Radiation Therapy A. Basic radiobiology and physics B. Orthovoltage vs. megavoltage C. Long and short term side effects of radiation therapy D. Radiation safety E. Acute Radiation Sickness F. Identify and ameliorate radiation therapy side effects V Knowledge of Patient Management A. Ability to classify and suggest pain management B. Complications of treatments (antiemetics, appetite stimulants, antidiarrheals, sepsis prevention, urothelial bladder wall protection, transfusion therapy) C. RECIST method (treatment response score) D. Chemoprotectants E. Nutritional support of the cancer patient, metabolic alterations F. Grief stages, counseling VI Organ and Systems Tumor sites A. Tumors Skin and Subcutaneous dog and cats B. Tumors of GI System 1. Oral Cavity (hard and soft palates, lips, cheeks) in dogs and cats 2. Tongue 3. Salivary Gland 4. Esophageal 5. Exocrine Pancreas 6. Gastric in dogs and cats 7. Hepatic in dogs and cats 8. GI Tract dogs and cats - small or large intestine 9. Perianal 10. Anal sac 11. Recto-anal 12. Peritoneal C. Tumors of Cardiovascular System D. Tumors of Respiratory System 1. Nasal Planum 2. Laryngeal 3. Tracheal 4. Lung 5. Nasal cavity dogs and cats 6. Mediastinum E. Tumors of Skeletal System Appendicular and Axial (skull, scapular, pelvic, rib, vertebral, nasal, paranasal) 1. Bone 2. Joint 3. Fat - 4 -
5 F. Tumors of Endocrine System 1. Thyroid 2. Pancreas 3. Adrenal G. Tumors of the Female Reproduction System 1. Uterus 2. Ovary 3. Vagina 4. Vulva H. Tumors of Mammary Glands I. Tumors of Male Reproduction Tract 1. Testicular 2. Prostate 3. Penis 4. Prepuce J. Tumors of Urinary Tract System 1. Renal 2. Bladder 3. Ureter 4. Urethra K. Tumors of Nervous System 1. Brain 2. Pituitary 3. Spine- extradural vertebral 4. Spine- extradural soft tissue 5. Spine- intradural, extramedullary 6. Intramedullary L. Ocular, retrobulbar tumors M. Otic, ceruminous gland, bulla tumors VII Hematopoietic and neutropoietic growth factors VIII Miscellaneous A. Mesothelioma B. Radiation induced sarcoma C. Metabolic emergencies D. Paraneoplastic syndromes and Hypercalcemia E. Disseminated intravascular coagulation F. Chemotherapy or radiation induced congestive heart failure G. Carcinomatosis H. Acute tumor lysis syndrome - 5 -
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