Renal Cancer. By Jamie Calderwood
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1 Renal Cancer By Jamie Calderwood
2 ("Kidney Cancer")*1 ("What are the different types of kidney mass?")*2
3 What is it? Renal cancer is more commonly known as kidney cancer. Wilms tumor Another name for kidney cancer is renal carcinoma. Most common type - renal cell carcinoma A common urologic tumor that accounts for about 3% of all human malignancies*4 Several subtypes of RCC
4 Causes of Renal Cancer Gene mutation in FH gene 20 different mutations discovered 2 were insertions 5 were deletions 13 were missense mutations *7
5 Types of Renal Cell Carcinoma Clear cell renal cell carcinoma Papillary renal cell carcinoma Chromophobe renal cell carcinoma Collecting duct renal cell carcinoma Unclassified renal cell carcinoma
6 Symptoms Blood in urine Low back pain on one side Mass/lump on side or lower back Tiredness Weight loss (not purposely) Fever that doesn't go away after a few weeks (not from infection) Anemia
7 Detection Lab Tests Blood tests Urinalysis Other "tests" Biopsy Fuhrman Grade Imaging Tests CT scan MRI scan Ultrasound PET scan IVP(Intravenous Pyelogram) Angiography Chest x-ray Bone scan
8 Stages of Renal Cancer ("Kidney Cancer")*5
9 Stages 1 and 2 Tumor is 7 cm or smaller Kidney only Has not spread Tumor is larger than 7 cm Kidney only Has not spread *8
10 Stage 3 Tumor of any size Located in kidney Spread to lymph nodes or has spread into major veins or perinephric tissue but not lymph nodes Not spread to other parts of body *8
11 Stage 4 Tumor has spread beyond connective tissue Spread to adrenal glands and possibly lymph nodes but not other parts of body or Tumor has spread to other organs(brain, lungs, bones) *8
12 Risk factors Lifestyle Smoking Weight Job-related Job hazards Inherited von Hippel-Lindua diease Hereditary papillary and leimyomarenal cell carcinoma Birt-Hobb-Dube Syndrome Hereditary renal oncocytoma Familial renal cancer
13 Other possible risk factors Gender Race Certain medicines Family history High blood pressure Advanced kidney disease
14 Treatments Surgical Nephrectomy Removing all or part of kidney Open radical Removal of entire kidney Open partial Removal of part of kidney with the tumor Laparoscopy "band aid surgery" less invasive two small incisions in abdominal wall *6 TREATMENT KILLS HEALTHY CELLS AS WELL! Therapy Chemotherapy only used after immunotherapy (Biologic Therapy) Immunotherapy Cytokines - proteins used to "turn on" immune system Radiation Therapy high-energy rays used to shrink tumors or kill cancer cells usually used to ease symptoms or problems caused by cancer spread stereotactic radiosurgery - used for single tumors that spread to the brain Targeted Therapy drugs used to stop growth of blood vessels that feed cancers drugs that stop other parts of cancer cell growth
15 If treatment stops working.. Palliative care doesn't cure cancer improves quality of life or help you feel as good as you can for as long as you can helps relieve symptoms Hospice care given at home focuses on comfort treats symptoms and problems caused by the cancer Stay hopeful!
16 Prevention Stop smoking Exercise to maintain healthy weight Choose diet high in fruits and vegetables Treat high blood pressure Avoid exposure to harmful substances in workplace
17 Citations 1. "Kidney Cancer." MyHealtheLink. Riverside Health System, 9 Feb Web. 22 Apr Hill, Erin J. "What Are the Different Types of Kidney Masses?" WiseGeek. Ed. Bronwyn Harris. Conjecture, 25 Mar Web. 22 Apr Kidney Cancer. "National Cancer Association." Kidney Cancer Home Page. National Cancer Institute, 7 Feb Web. 11 Feb Schrader, Andres Jan. 'Overweight is associated with Improved cancer-specific Survival in Patients with organ-confined renal cell carcinoma." Journal of Cancer Research and Clinical Oncology (2009): 1. Proquest Research Library. Web. 22 Apr "Kidney Cancer." Windham Urology Group P.C. Web. 22 Apr Kidney Cancer Association. "Kidney Cancer Association - The World's Most Respected Fully Accredited Kidney Cancer Charity." Kidney Cancer Association RSS. Kidney Cancer Association, 29 Jan Web. 14 Feb Toro, Jorge R. "Mutations in the Fumurate Hydratase Gene Cause Hereditary Leiomyomatosis and Renal Cell Cancer in Families in North America." NCBI 73 (2003): PMC. Web. 22 Apri "Kidney Cancer." Cancer.net. American Society of Clinical Oncology, Apr Web. 22 Apr, 2013.
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