Director of BK21 Project for Medical Science Professor Kim, Hoguen Tel : /

Transcription

1 Director of BK21 Project for Medical Science Professor Kim, Hoguen Tel : / hkyonsei@yuhs.ac Contact Address (Office) BK21 Project for Medical Science Yonsei University College of Medicine 250 Seongsanno, Seodaemun-gu, Seoul , Korea Tel : ~7/ Fax : / bk21@yuhs.ac, bk21ces@yuhs.ac

2 Table of Contents Dean s Message Director s Message About Us, Vision and Goals Organization Structure Faculty Members and Research Programs and Fellowships Scholarships Major Research Equipments Appendix 1

3 Dean's Message Namsik Chung Dean of Yonsei University College of Medicine It has already been two years since Yonsei University College of Medicine began the second phase of the Brain Korea 21 Project for Medical Science in 2006, based on the successful achievements of the first six-year phase of the project from 1999 to In the last two years, we have surpassed our initial goals thanks to participating faculty members, new research personnel, graduate students and other supportive staff members. I hereby would like to extend my gratitude and encouragement to all of those who have been constantly endeavoring to achieve even better results in 2008, including the Director of the Brain Korea 21 Project for Medical Science. The competitiveness of a medical school is evaluated by both its production of outstanding human resources and its research achievements. The professors participating in the school s BK 21 Project for Medical Science and the more than 220 students who are conducting basic research essential to the project are like points of light illuminating the future. With its goal to become an educational organization of leading medical technologies and innovations by creating new research areas and by being the most desired place to study for students, the BK 21 Project for Medical Science of Yonsei University College of Medicine will continue to provide students with the opportunity to grow and to make valuable contributions to the development of the field of medicine. It will also play a crucial role in enhancing the school s research potential. In order to realize the greatest synergy effect, from now on we will focus on research by emphasizing investment in joint research projects involving faculty and schools in global-level, industry-academic cooperation. We are also exerting our effort to secure more research space on campus and to expand on our already substantial assistance for students. Hoguen Kim Director, Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine Director's Message On 03 behalf of the members of the Yonsei University Medical Center, I would like to introduce our Graduate School of Medical Science. The Graduate School of Medical Science has been supported by the Korean government as the Brain Korea 21 Project for Medical Science since Today, the Graduate School of Medical Science has more than 220 graduate students and 120 selected professors from Yonsei University Medical Center. Our educational goal is to extend the lives of patients and improve their quality of life. Life science is now a vast multidisciplinary field encompassing most areas of science and technology. There is an increasing trend toward conducting basic research that is influenced by clinical observations, and the rapidly developing fields of molecular biology and genetics directly influence clinical research. The synergies across the basic and clinical fields will deepen our knowledge. Reflecting the high quality of research and support from Yonsei University, our program has provided a variety of scholarships, including full scholarships, for a number of qualified students. We also offer many comprehensive scientific programs and state-of-the-art facilities for laboratory, transitional and clinical research. With advanced research technologies and generous academic and financial support, our graduate students have published numerous papers in top quality academic journals. Emphasizing the fact that research can grow through the support and encouragement of participating professors and researchers, graduate students and school staff members, in addition to substantial financial assistance, I would like to once again express my deep appreciation to all involved for their contributions to the successful execution of the project since its inception. We would like to invite students from all over the world to apply for our program. I know those who join us will find it beneficial to their development as graduate students and science researchers. Sincerely, August August

4 Vision To become a world-class leading research institute in the field of medical science. 04 About Us F unded by the Ministry of Education, Science, and Technology, the Brain Korea 21 Project for Medical Science at Yonsei University College of Medicine supports the training of basic biomedical researchers with strong clinical backgrounds to improve the manner in which biomedical research is conducted in medical schools. Since 1999, the project has been promoting seven independent specialized training units with the common theme of Gene to Cure. It has been fulfilling the critical need to train the next generation of biomedical researchers in Korea. It strives to become the leading program by offering the highest level of education and training, thereby enabling future scientists to be at the cutting edge of international biomedical research. While Yonsei University College of Medicine prides itself on providing state-of-the-art care to patients throughout its more than 100-year history, it is through biomedical research and the nurturing of new researchers that this institute has been able to positively impact the field of medicine. The most essential elements of the project are to design and run multidisciplinary training programs, offer tuition assistance, provide state-of-theart experimental equipment, and cover travel expenses for our researchers to travel abroad and connect with researchers from around the world. At the forefront of biomedical research in Korea, the Brain Korea 21 Project for Medical Science will continue to focus on making medical breakthroughs. Goals To establish a graduate program that fosters creative, multidisciplinary and interdepartmental biomedical research that benefits the next generation of scientists. To support and promote research to cure human diseases. To improve the quality of research and ensure the institute s excellence in the medical science field. 4 5

5 05 Organization Structure Immunology Neuroscience Cancer Biology Biomedical Science & Engineering Cell Biology & Pharmacology Molecular Genetics & Pathology Human Structure & Developmental Biology Team1 Kim, Jongsun Team6 Ahn, Young Soo Team10 Song, Si Young Team14 Lee, Hyun Chul Team18 Kim, Kyung Sup Team22 Park, Young Nyun Team26 Yoon, Joo Heon Team2 Lee, Kwang Hoon Team7 Lee, Byung In Team11 Cho, Nam Hoon Team15 Kang, Shin Wook Team19 Nam, Taick Sang Team23 Jang, Yang Soo Team27 Ha, Jong Won Team3 Yong, Tai Soon Team8 Chang, Jin Woo Team12 Chung, Hyun Chul Team16 Suh, Il Team20 Kim, Kyung Hwan Team24 Kim, Dong Seok Team28 Kim, Sung Jae Team4 Shin, Jeon-Soo Team9 Kim, Dong Goo Team13 Kim, Joo Hang Team17 Kim, Deok Won Team21 Lee, Min Goo Team25 Lee, Jin-Sung Team29 Han, Sang Won 6 Team5 Lee, Kyungwon 7

6 Immunology 06 Faculty Members and Research Biomedical Science & Engineering 14 Diabetes and Metabolic Disease Lee, Hyun Chul Kang, Eun Seok Cha, Bong Soo 15 Renal Disease Kang, Shin Wook Lee, Jae Seung Lee, Duk Chul Suh, Il Won, Jong Uk Nam, Chung Mo 16 Chronic Diseases Epidemiology Shin, Dong Chun Ohrr, Heechoul 17 Biomedical Engineering Kim, Deok Won Park, Jong Chul Park, Hae Jeong Yoo, Sun Kook 1 Natural Immunity-Disease Defense Kim, Jongsun Kim, Kyu Earn Lee, Jae Myun 2 Skin Immunology Lee, Kwang Hoon Lee, Min-Geol Lee, Seung Hun 3 Allergy and Parasitology Yong, Tai Soon Park, Jung Won Shin, Myeong Heon 4 Autoimmunity and Inflammatory Reaction Shin, Jeon-Soo Kim, Soo-Chan Lee, Soo Kon Choi, In-Hong 5 Infectious Disease Lee, Kyungwon Cho, Sang-Nae Cell Biology & Pharmacology Kim, Kyung Sup Ahn, Yong Ho Park, Soon Jung 18 Gene Expression Regulation Hur, Man Wook Kim, Jae-Woo 19 Stem Cell Division Nam, Taick Sang Kim, Dong Wook Ahn, Duck Sun Chung, Seung soo 20 New Drug Assessment Technique Kim, Kyung Hwan Park, Kyungsoo Yoon, Ho Geun Kim, Joo Young 21 Gastrointestinal Pharmacology Lee, Min Goo Park, Hyo Jin Lee, Yong Chan Park, Sahng Wook Neuroscience 6 Development of Defense and Control Mechanisms Against Neuronal Cell Death Ahn, Young Soo Kim, Chul Hoon Lee, Jong Eun Ahn, Jung Yong 7 Neuroprotection Lee, Byung In Sohn, Young Ho Choi, Young-Chul Heo, Ji Hoe 8 Neurophysiology and Neurosurgery Chang, Jin Woo Kim, Jeong-Hoon Yoon, Do Heum Lee, Bae Hwan 9 Higher Mental Function Analysis and Control Technology Development Kim, Dong Goo Kim, Jae-Jin Park, Kook In Lee, Jong Doo Molecular Genetics & Pathology 22 Mechanism of Liver Disease Park, Young Nyun Park, Jeon Han Paik, Yong Han Han, Kwang Hyub 23 Cardiovascular Disease Jang, Yang Soo Lee, Young Ho Chung, Nam Sik Chung, In Hyuk Choi, Eui-Young 24 Brain Tumor Kim, Dong Seok Kim, Tai Seung Shin, Kyoung Jin Yang, Woo Ick Kim, Eung Yeop 25 Biomarker of Gastrointestinal Tract Cancer Lee, Jin-Sung Kim, Nam Kyu Kim, Myeong Jin Kim, Hoguen Cho, Woo Hyun Cancer Biology Song, Si Young Kim, Kun Hong Lee, Dong Ki 10 Gastrointestinal Tumor Biology Kim, Won Ho Yu, Jeong-Sik 11 Germ Cell Tumor Cho, Nam Hoon Kim, Young Tae Choi, Young Deuk Hong, Sung Joon 12 Tumor Molecular Genetics Chung, Hyun Chul Noh, Sung Hoon Rha, Sun Young Seong, Jinsil 13 Oncogene Discovery and Gene Therapy Kim, Joo Hang Kim, Gwi Eon Moon, Seong Hwan Park, Byeong Woo Yun, Chae-Ok Human Structure & Developmental Biology 26 Mucous Biology Yoon, Joo Heon Bai, Sang Wook Choi, Jae Young Lee, Jin Woo 27 Cardiovascular Circulatory Organ Physiology Ha, Jong Won Kwak, Young Lan Kang, Seok Min 28 Musculoskeletal System Cell Biology Kim, Sung Jae Suh, Jin Suck Lim, Sung Kil 29 Urogenital Functional Disorder Han, Sang Won Kim, Myoung Hee Bok, Jinwoong Lee, Hye Yeon 8 9

7 Immunology Neuroscience 06 Research Group Leader Kim, Jongsun T he immunology research team carries out multiple studies in the areas of basic immunology and applied clinical immunology, which are concerned with the relationship between host immunity and diseases as well as the areas of immunotherapy. The team is further divided into five sub-groups, and 15 specialists from all five teams collaborating with each other to conduct research in this particular field. Immunology Team 1, Natural immunity-disease defense team Team 1 is in charge of research on factors influencing the natural immunity-disease defense system such as NK cells, macrophage, neutrophils, and the therapeutic applications to combat cancers, infectious diseases, respiratory diseases and autoimmune diseases. Immunology Team 2, Skin immunology research team Team 2 is in charge of studying the role of lymphocytes and their control factors in atopic dermatitis, contact dermatitis and psoriasis. Immunology Team 3, Allergy and Parasitology team Team 3 focuses on the identification of causative agents and the corresponding treatments for host allergic reactions as well as the study of the relationship between parasitic organisms and the related mechanisms of the subsequent immune reactions. Immunology Team 4, Autoimmunity and inflammatory reaction team The aims of this research team are to identify the specific mechanisms of autoimmune reactions and understand the control mechanisms of immune reactions in detail. Immunology Team 5, Infectious disease research team Team 5 carries out experiments to identify the pathogenic mechanisms of bacteria, viruses and fungi in order to develop new diagnostic and therapeutic tools by discovering the host immune factors that are specifically related to the corresponding diseases. Group Leader Ahn, Young Soo The neuroscience research team carries out multiple studies in neurophysiology, defense and control mechanisms of neuronal cell death neural stem cell and brain imaging. The team is further divided into 4 sub-groups and 17 specialists. Neuroscience Team 6, Development of defense and control mechanisms against neuronal cell death Team 6 concentrates on discovering the potential signal transduction pathway that is involved in preventing neuronal cell death by using biochemical, pharmacological, and functional imaging techniques. In doing so, the team expects to discover effective drug treatments. Neuroscience Team 7, Neuroprotection research team Team 7 studies the mechanisms and treatments of: (1) the mechanisms of ischemic neuronal cell death, (2) the protection mechanisms against epileptogenesis, (3) the plasticity of specific neural circuitry using genetic neural tracers in focal and global ischemia, pilocarpine-induced epilepsy, and aged animal models. Neuroscience Team 8, Neurophysiology and neurosurgery research team Team 8 studies the mechanisms and treatments of: (1) motor disabilities, (2) disabilities resulting from the spinal damage, (3) drug addiction, (4) the sensory and motor disabilities resulting from nerve damage, and (5) the mechanisms of pain and the ways to alleviate it. Neuroscience Team 9, Higher mental function analysis and control technology development Through multidisciplinary collaborations, basic scientists, clinical researchers and imaging researchers work together to discover new theories and treatment schemes in higher mental function studies via new imaging techniques and various research methods covering the entire range from the behavioral stage to the molecular stage

8 Cancer Biology Biomedical Science & Engineering Group Leader Song, Si Young Group Leader Lee, Hyun Chul Cancer is still the most common life-threatening disease in the 21st century. In order to discover cures for cancer, continuously active development is required to generate new approaches to drug discovery, accurate diagnosis, prevention and safe and efficient treatment. Together with clinical research applying the bottom-up method based on therapeutic application, it will be possible to control cancers with effective interventions. Currently, the following multi-disciplinary tumor biology research teams are actively conducting various research projects to achieve the ultimate goals of cancer therapy. The team is further divided into four sub-groups and 18 specialists. Cancer biology Team 10, Gastrointestinal tumor biology research Through the development of methods to analyze the molecular function and cellular regulation of tumors, Team 10 aims to discover a more effective diagnosis, prevention, and treatment for GI tract cancer, which accounts for more than 55% of the deaths caused by cancer. Cancer biology Team 11, Germ cell tumor research Team 11 investigates the pheno-genotypic relationship in tumors of the prostate, male testes, female ovaries and the uterus. Cancer biology Team 12, Tumor molecular genetics research Team 12 works to identify the mechanisms of tumorigenesis, progression, and metastasis through molecular genetics studies, and to develop a new anti-cancer therapy. Cancer biology Team 13, Oncogene discovery and gene therapy research This team plans to develop a cancer gene therapy and to verify tumor markers or tumor-related factors by using various research methods. Through integrated and co-operative interaction with the other tumor biology research teams, Team 13 is planning to develop improved and more efficient anti-cancer therapies. The biomedical science and engineering teams carry out multiple studies in endocrinology, metabolic syndrome, renal diseases, chronic disease epidemiology and bioengineering. The team is further divided into 4 sub-groups and 15 specialists. Biomedical Science & Engineering Team 14, Diabetes and metabolic disease research Team 14 studies 1) diabetic complications and the development of new drugs, 2) the pathogenic mechanisms of energy metabolism, 3) the pharmacogenetics of diabetes research, and 4) the stem cell research for curing diabetes by identifying the key pathogenic causes in diabetes and metabolic syndrome, and by building a research foundation for developing new drugs. Biomedical Science & Engineering Team 15, Renal disease research Team 15 conducts internal and external biological experiments with the purpose of identifying the pathophysiology of diabetic nephropathy and developing drugs for treatment. Biomedical Science & Engineering Team16, Chronic disease epidemiology research Team 16 primarily conducts studies on cardiovascular diseases. By analyzing the existing Kangwha cohort studies, the natural changes in the patterns of blood pressure from childhood to adulthood were presented. This team is expected to continue this research to analyze the changes in the incidences and the growth-dependent risk factors of cardiovascular diseases. Additionally, the researchers are also conducting genetic epidemiology studies related to cardiovascular diseases by considering a wide range of potential risk factors. Biomedical Science & Engineering Team 17, Biomedical engineering research Team 17 was formed to analyze and find solutions to various issues concerning the prevention, diagnosis, and treatment of diseases by adapting the theories and technologies in the natural science and bioengineering fields. By integrating fundamental and clinical medicine with a diverse range of engineering technologies, the research team aims to apply new scientific and engineering concepts that involve the design and development of cutting-edge medical equipment, with the hope that the studies will eventually contribute to making a better quality of life in terms of human welfare, medical diagnosis and therapy

9 Cell Biology & Pharmacology Molecular Genetics & Pathology Group Leader Kim, Kyung Sup Group Leader Park, Young Nyun Cells continuously exchange information with their external environment, and control and undergo many finely-tuned chemical reactions. As a result, they go through the process of differentiation, growth, proliferation and death. The cell biology & pharmacology research team studies the mechanisms of these cellular processes and their applications to clinical medicine. The team is further divided into four sub-groups and 18 specialists. Cell Biology & Pharmacology Team 17, Gene expression regulation research Team 18 studies various regulatory mechanisms of gene expression levels during the process of transcription, translation and the post-translational modification of proteins. Cell Biology & Pharmacology Team 19, Stem cell division research Team 19 aims to develop a new technology to assist stem cells as they divide and differentiate into specific cells. This research will lead to the development of new treatment techniques that can be applied to disease models by assessing the functions of differentiated cells from the cellular level. Cell Biology & Pharmacology Team 20, New drug assessment technique research Team 20 aims to study and develop techniques to evaluate the safety and efficacy of new drug candidates within the human body by using new models and simulations as well as other available tools. Cell Biology & Pharmacology Team 21, Gastrointestinal pharmacology research Team 21 analyzes gastrointestinal functions by using molecular biology techniques, and aims to discover potential substances for the purpose of treating the related diseases. The Molecular Genetics and Pathology research team focuses on the molecular biological aspects of liver diseases, gastrointestinal cancers, brain tumors and atherosclerosis as cardiovascular diseases. Nineteen professors comprise this team, which is further divided into 4 sub-groups. Molecular Genetics & Pathology Team 22, Mechanism of liver disease research Hepatocellular carcinoma (HCC) usually occurs during the cirrhosis phase of the chronic inflammatory process, and hepatitis B virus and hepatitis C viruses are its main causes. Recently, evidence supporting the theory of a multistep process of human hepatocarcinogenesis has been growing. Our team focuses its studies on the molecular pathogenesis of multistep hepatocarcinogenesis, including precancerous lesions and cancer stem cells, hepatitis viruses (B and C) and hepatic fibrogenesis. We believe that these studies will help to develop new techniques for preventing and treating chronic liver diseases and HCC. Molecular Genetics & Pathology Team 23, Cardiovascular disease research Team 23 focuses on the analysis of genetic factors involved in atherosclerosis by applying genetic polymorphism of cardiovascular related genes. We believe that these studies will help to develop new techniques for preventing and treating the diseases by predicting the risk factors of cardiovascular diseases. Molecular Genetics & Pathology Team 24, Brain tumor research Team 24 studies the pathogenic mechanisms of brain tumors and emphasizes re-classifying brain tumors according to their molecular and biological characteristics. The ultimate goal of Team 24 is to develop new treatment strategies for brain tumors based on such biological and molecular data. Molecular Genetics & Pathology Team 25, Biomarkers of gastrointestinal tract cancers Many diseases are known to originate from genetic changes. Therefore, by studying and identifying the related genetic mutations, we can develop techniques for diagnosis, treatment, and prevention of the diseases based on such genetic information. Team 25 aims to find the specific biomarkers for gastrointestinal tract tumors that will aid the early diagnosis of gastrointestinal tract cancers

10 Human Structure & Developmental Biology 07 Programs and Fellowships Group Leader Yoon, Joo Heon The human structure and developmental biology research team is divided into four sub-groups, and 14 academic professors are involved in the research. Human Structure & Developmental Biology Team 26, Mucous biology research Team 26 focuses on conducting translational research for the development of treatments against hyper-secretions of mucus in order to develop ways to control mucous secretion and expression in epithelial cells. Human Structure & Developmental Biology Team 27, Cardiovascular circulatory organ physiology research The goal of Team 27 is to identify the pathogenic mechanisms in myocardial functions by accurately assessing cardiac functions, identifying the causes of heart failure and developing new therapies for cardiovascular diseases. Human Structure & Developmental Biology Team 28, Musculoskeletal system cell biology research Team 28 studies the pathogenic mechanisms of musculoskeletal disorders, and is interested in developing regenerative medical approaches as a treatment as well as designing and evaluating practical new drug candidates. Human Structure & Developmental Biology Team 29, Uro-genital functional disorder research Team 29 deals with a wide range of research areas, from various human developmental abnormalities to urogenital cancers. From looking at abnormalities the genetic level to studying organ dysfunction due to the defects in the autonomic nervous system, the team strives to develop new treatments to fight regulatory dysfunctions. 1. Graduate Program The mission of the Graduate School of Medical Science at Yonsei University is to provide excellent educational opportunities for students in a stimulating environment that includes both basic and clinical research. 120 faculty members with common interests in graduate education and basic biomedical and clinical scientific research comprise the graduate school faculty in a particular program of study. The Graduate School of Medical Science at Yonsei University offers Master s and Ph.D. degrees in seven different programs of study: Immunology Neuroscience Cancer Biology Biomedical Science & Engineering Cell Biology and Pharmacology Molecular Genetics & Pathology Human Structure & Developmental Biology These programs offer a selection of various courses ranging from basic sciences to their clinical applications

11 Core Course: Immunology General Biochemistry Neurobiology Tumor Biology Human Structure & Function Principle of Drug Action Pathobiology Structure & Developmental Biology Special Lecture for Medical Science Biomedical Research Ethics Elective Course: Brain, Mind, Behavior Neuroanatomy Methodology Used in Current Molecular Biology Molecular Immunology Diabetes Parasitology and Tropical Medicine Evaluation of Medical Devices Molecular Cell Biology Electrophysiology Principles and Application of Advanced Medical Equipments Cutting Edge Experimental Techniques in Medical Science Seminar for Human Natural Defense Mechanism Introduction to Epithelial Cell Biology Immunology Mechanisms in Disease Laboratory Animal Medicine Cancer Genomics Neurophysiology Molecular Basis of Inherited Disease Gene Delivery System Tumor Immunology Learning & Memory Bone and Mineral Metabolism Vascular Biology Advanced Cell Biology Introduction to Human Embryology Computerized Biological System Analysis Regulation of Gene Transcription Molecular Pathology of Gastrointestinal Disease 2. Requirements for Graduation Master s Degree: 30 credits with thesis Ph.D. Degree: 60 credits with thesis and a dissertation to be published in internationally recognized journals (SCI(E) journals) 3. International Collaboration Institutes Graduate students and postdoctoral fellows have the opportunity to further develop their research capabilities in other countries through participation in international scientific conferences, joint symposia and workshops with foreign institutes, or international exchanges and collaboration programs

12 International Collaborating Institutes: 08 Scholarships University of Mississippi Medical School University of San Diego, Burnham Institute University of Texas Southwestern Medical School and Graduate School of Biomedical Science 4. Fellowships and Grants Every student admitted to the Graduate School of Medical Science at Yonsei University is provided a BK21 tuition fellowship. In addition to the BK21 fellowships, a number of graduate students are also supported by internal scholarships at Yonsei University. The Graduate School of Yonsei University offers financial assistance to international students with excellent academic records. The administration of the Graduate School of Medical Science at Yonsei University has provided funding for graduate students to support research that constitutes a portion of their degree requirements. The purpose of this funding is to foster graduate education and research, and to contribute to the quality of research in general on this campus. The Graduate School offers travel cost funding for graduate students who attend national or international meetings in order to formally present their research in a poster or podium format. 1. Number of Students (No.) 20 21

13 09 Major Research Equipments 2. Scholarship (US$) MALDI-TOF (Matrix-Assisted Laser Desorption/ Ionization Time-Of-Flight) mass spectrometer Mass spectrometry using soft ionization for the analysis of biomolecules (biopolymers such as proteins, peptides and sugars) and large organic molecules (such as polymers, dendrimers and other macromolecules). 3. Overseas Training Support (US$) HPLC (High Performance Liquid Chromatography) Column chromatography used frequently in biochemistry and analytical chemistry to separate, identify, and quantify compounds. Luminex (multiplex liquid array system) An array system based on xmap technology (multianalyte profiling beads) enabling the detection and quantitation of multiple RNA or protein targets simultaneously

14 10 Appendix Name Research Field Ahn, Duck Sun TRP Channel, Pain Perception Mechanism Q-TOF mass spectrometer Mass spectrometer used for analysis of polar or ionic organic compounds by electrospray or APCI ionization. A Ahn, Jung Yong Ahn, Yong Ho Ahn, Young Soo Neuro-Oncology, Neuro-Genetics Metabolically Controlled Gene Expression Neuropharmacology, Molecular Pharmacology jyahn@yuhs.ac yha111@yuhs.ac ahnys@yuhs.ac B Bai, Sang Wook Bok, Jinwoong Pathophysiology of Pelvic Organ Prolapse Vertebrate Inner Ear Development swbai@yuhs.ac bokj@yuhs.ac Cha, Bong Soo Insulin Resistance, DM & Obesity bscha@yuhs.ac Chang, Jin woo Stereotactic Functional Neurosurgery jchang@yuhs.ac Cho, Nam Hoon Pheno-Genomic Based Molecular Pathology cho1988@yuhs.ac TIRF (Total Internal Reflection Fluorescence) microscope Fluorescence microscopy where excitation light is confined to a small area at the interface of the specimen and the glass coverslip or culture vessel. TIRF allows nanometre-scale imaging of single molecules. C Cho, Sang-Nae Cho, Woo Hyun Choi, Eui-Young Choi, In-Hong Choi, Jae Young Mycobacterium Tuberculosis Hospital Management, Quality in Health Care Cardiovascular Imaging in Heart Failure Toll-like Receptor,Toxicology of Nanomaterials Airway Mucus, Airway Epithelial Cell Culture raycho@yuhs.ac whcho@yuhs.ac choi0928@yuhs.ac inhong@yuhs.ac jychoi@yuhs.ac Choi, Young Deuk Urogenital Tumor, Prostate youngd74@yuhs.ac Choi, Young-Chul Neuroscience, Immunology, Neurology, Myology ycchoi@yuhs.ac Chung, Hyun Chul Angiogenesis & Metastasis, Cancer Genomics unchung8@yuhs.ac Confocal microscope An optical imaging technique used to increase micrograph contrast and/or to reconstruct threedimensional images by using a spatial pinhole to eliminate out-of-focus light or flare in specimens that are thicker than the focal plane. Chung, In Hyuk Chung, Nam Sik Chung, Seungsoo Clinical Anatomy, Physical Anthropology Coronary Heart Disease, Hypertension Neuronal Stem Cell, Applied Cell Therapy chinhy@yuhs.ac namsikc@yuhs.ac sschung@yuhs.ac 24 25

15 Name Research Field Name Research Field Ha, Jong Won Cardiovascular Aging, Exercise Physiology Kim, Kun Hong Apoptosis and Metastasis of Cancer Han, Kwang Hyub Chronic Viral Liver Disease Kim, Kyu Earn Allergy, Innate Immunity, Respiratory Diseases H Han, Sang Won Heo, Ji Hoe Pediatric Urology, Congenital Anomaly Stroke jhheo@yuhs.ac Kim, Kyung Hwan Kim, Kyung Sup Secretory Mechanism in Pancreas, Stomach Gene Expression of Lipogenic Enzymes kyungsup59@yuhs.ac Hong, Sung Joon BPH & Prostate Cancer, Chemoprevention Kim, Myeong Jin Abdominal Imaging, CT & MRI Hur, Man Wook Biological Complexity, Disease of Transcription Kim, Myoung Hee Vertebrate Development, Pattern Formation J Jang, Yang Soo Jeon, Woo Taek Cardiovascular Disease Social, Culture Psychiatry, Unification wtjeon@yuhs.ac K Kim, Nam Kyu Kim, Soo-Chan Colorectal Cancer, Liver Metastasis Immunodermatology, Contact Dermatitis namkyuk@yuhs.ac kimsc@yuhs.ac Kang, Eun Seok Genetic Epidemiology in Diabetes edgo@yuhs.ac Kim, Sung Jae Knee Surgery & Orthopaedic Sports Medicine sungjaekim@yuhs.ac Kang, Seok Min Heart Failure smkang@yuhs.ac Kim, Tai Seung Brain Tumor solto@yuhs.ac Kang, Shin Wook Podocyte Biology in Diabetic Nephropathy kswkidney@yuhs.ac Kim, Won Ho Mucosal Immunology kimwonho@yuhs.ac Kim, Chul Hoon mglur, Synaptic Plasticity, Cell Death kimhoon@yuhs.ac Kim, Young Tae Oncoprotein and Gynecologic Cancer ytkchoi@yuhs.ac Kim, Deok Won Biomedical Instrumentation kdw@yuhs.ac Kwak, Young Lan Myocardial Protection in Adult Cardiac Surgery ylkwak@yuhs.ac Kim, Dong Goo Stress, Developmental Disability dgkimpharm@yuhs.ac Lee, Bae Hwan Neural Injury and Sensorimotor Dysfunction bhlee@yuhs.ac Kim, Dong Seok Genetics, Brain Invasion of Glioma dskim33@yuhs.ac Lee, Byung In Epileptogenesis, Neuronal Ischemic Injury bilee@yuhs.ac Kim, Dong Wook Stem Cell Biology dwkim2@yuhs.ac Lee, Dong Ki Development of Drug-Eluting Biliary Metal Stent dklee@yuhs.ac K Kim, Eung Yeop Stroke Imaging, Imaging of Brain Development eungykim@yuhs.ac Lee, Duk Chul Health Promotion and Related Risk Factors faith@yuhs.ac Kim, Gwi Eon Head & Neck Cancer, Gynecologic Cancer gekim@yuhs.ac Lee, Hye Yeon Surgical Anatomy of the Cranial Nerve leehy@yuhs.ac Kim, Hoguen Kim, Jae-Jin Genomic Instability, Microsatellite Instability Neuroimaging, Virtual Reality, Schizophrenia hkyonsei@yuhs.ac jaejkim@yuhs.ac L Lee, Hyun Chul Lee, Jae Myun DM and Obesity Tumor Virology(EBV,HCV), mirna endohclee@yuhs.ac jaemyun@yuhs.ac Kim, Jae-Woo Adipocyte Differentiation, DM & Obesity japol13@yuhs.ac Lee, Jae Seung Matrix Metalloproteinases and Kidney jsyonse@yuhs.ac Kim, Jeong-Hoon Brain Rewarding System and Drug Addiction jkim1@yuhs.ac Lee, Jin Woo Cartilage, Stem Cell, Tendinosis ljwos@yuhs.ac Kim, Jongsun NK Cell and Tumor Immunology jkim63@yuhs.ac Lee, Jin-Sung Functional Genomics, Genetic Disease jinsunglee@yuhs.ac Kim, Joo Hang Cancer Gene Therapy, Molecular Biology kjhang@yuhs.ac Lee, Jong Doo Functional Neuroimaging jdlee@yuhs.ac Kim, Joo Young Calcium Signaling, Epithelial Biology jooyoungkim@yuhs.ac Lee, Jong Eun CNS Injury, Neuroregeneration jelee@yuhs.ac 26 27

16 Name Research Field Name Research Field Lee, Kwang Hoon Proteomics, Endothelial Cells, Skin Aging Park, Kyungsoo Clinical Pharmacology Lee, Kyungwon Lee, Min Goo Antimicrobial Resistance Pharmacogenomics of Drug Transporters P Park, Sahng Wook Park, Soon Jung Regulation of LDL Metabolism by PCSK9 Virulence Determinants of Human Pathogens swpark64@yuhs.ac sjpark615@yuhs.ac Lee, Min-Geol Dendritic Cell Biology, Contact Hypersensitivity mglee@yuhs.ac Park, Young Nyun Hepatocarcinogenesis young0608@yuhs.ac L Lee, Seung Hun Lee, Seung-Koo Lee, Soo Kon Skin Barrier Neuroradiology, Perfusion, Pediatric Neuroradiology Rheumatoid Arthritis, SLE ydshderm@yuhs.ac slee@yuhs.ac sookonlee@yuhs.ac R Rha, Sun Young Roh, Jaehoon Seong, Jinsil Chemotherapy in Stomach Cancer Occupational Medicine Radiation Biology rha7655@yuhs.ac jhroh@yuhs.ac jsseong@yuhs.ac Lee, Yong Chan Helicobacter Pylori, Gastric Cancer leeyc@yuhs.ac Shin, Dong Chun Environmental Health Risk Assessment dshin5@yuhs.ac Lee, Young Ho Vascular Contractility and Vascular Diseases yhlee@yuhs.ac Shin, Jeon-Soo Infection, Immunity and Immune Regulation jsshin6203@yuhs.ac Leem, Joong Woo Neuropathic Pain, Pharmacology of Pain jwleem@yuhs.ac Shin, Kyoung Jin Forensic Genetics and Ancient DNA kjshin@yuhs.ac Lim, Sung Kil Osteoporosis, Stem Cell Differentiation, Obesity lsk@yuhs.ac S Shin, Myeong Heon Pathogen-Induced Immune Modulation in Host myeong@yuhs.ac Lyu, Chuhl Joo Pediatric Hematology and Oncology cj@yuhs.ac Sohn, Young Ho Dementia yhsohn62@yuhs.ac M Moon, Seong Hwan Spine, Intervertebral Disc, Gene Therapy shmoon@yuhs.ac Song, Si Young Pancreatic Cancer, Gastric Cancer sysong@yuhs.ac Nam, Chung Mo Statistical Modeling of Biomedical Data cmnam@yuhs.ac Suh, Il Cardiovascular Disease Epidemiology isuh@yuhs.ac N Nam, Taick Sang Neuropathic Pain & Neuronal Stem Cells tsnam@yuhs.ac Suh, Jin Suck Nano-Medical Imaging & Molecular Imaging jss@yuhs.ac Noh, Sung Hoon Cancer Metastasis and Treatment sunghoonn@yuhs.ac W Won, Jong Uk Occupational Health Service Management juwon@yuhs.ac O Ohrr, Heechoul Cancer Epidemiology ohrr@yuhs.ac Yang, Eun Bae Curriculum Development and Evaluation nara@yuhs.ac Paik, Yong Han Liver Diseases yhpaik@yuhs.ac Yang, Woo Ick Hematologic Malignancies wiyang9660@yuhs.ac Park, Byeong Woo Estrogen Receptor, Tumor Marker, Breast Cancer bwpark@yuhs.ac Yong, Tai Soon Parasitology, Allergy, Medical Entomology tsyong212@yuhs.ac Park, Hae Jeong Molecular Neuroimaging Technology parkhj@yuhs.ac Yoo, Sun Kook Telemedicine, Ubiquitous Health Care sunkyoo@yuhs.ac P Park, Hyo Jin Park, Jeon Han Neurogastroenterology and Motility Apoptosis, Pathogenesis of Liver Cancer hjpark21@yuhs.ac jhpark5277@yuhs.ac Y Yoon, Do Heum Yoon, HoGeun Spine Neurosurgery The Role of Epigenetic Protein Complexes ydoheum@yuhs.ac yhgeun@yuhs.ac Park, Jong Chul Biocompatibility, Cell Migration, Sterilization parkjc@yuhs.ac Yoon, Joo Heon Airway Mucus, Airway Epithelial Cell Culture jhyoon@yuhs.ac Park, Jung Won Pathogenesis and Clinical Aspects of Asthma parkjw@yuhs.ac Yu, Jeong-Sik Liver Imaging (CT, MRI) yjsrad97@yuhs.ac Park, Kook In Neural Stem Cells kipark@yuhs.ac Yun, Chae-Ok Cancer Gene Therapy, Targeted Therapy chaeok@yuhs.ac 28 29