SHEDDING A LITTLE LIGHT ON THE BIGGER PROBLEM
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1 NationalPCF.org
2 SHEDDING A LITTLE LIGHT ON THE BIGGER PROBLEM 1.7 MILLION NEW CANCER CASES EVERY YEAR 600,000 PEOPLE WILL DIE More than of those who survive childhood cancer will have a significant health related issue as a result of treatment with drugs designed for adults. Cancer is the number one cause of death by disease among children. 43 children per day are expected to be diagnosed with cancer. Only 4 % of the billions of dollars that are annually spent on cancer research and treatments are directed towards treating childhood cancer.
3 WHAT IS CANCER? Cancer is a genetic disease it is caused by changes to genes that control the way our cells function, especially how they grow and divide.
4 WHAT ARE THE TYPES OF PEDIATRIC CANCER? Types of Pediatric Cancer: Brain Leukemia Lymphoma Neuroblastoma Sarcoma Wilms
5 WHAT ARE THE STAGES OF PEDIATRIC CANCER? Stages of Cancer Stage 0 : abnormal cells are present but have not spread Stage 1 : usually a small cancer or tumor that has not grown deeply into nearby tissues Stage 2 and 3 : the cancer has spread and has grown deeply into the surrounding tissues Stage 4 : the cancer has spread to distant parts of the body
6 WHAT ARE PEDIATRIC CANCER TREATMENTS? Cancer Treatments: Surgery removal of the cancer Radiation Therapy used to kill cells or shrink tumors Chemotherapy drugs that kill cancerous cells Immunotherapy helps immune system battle the cancer Targeted Therapy targets the changes in the cell to stop growth and spreading Stem Cell Transplant restore blood-forming stem calls that have been destroyed by chemo and/or radiation Precision Medicine allows Drs. to select treatments that will best help based on genetics of the disease
7 WHERE DOES PEDIATRIC CANCER GET TREATED? 1. Primary Care Physician 2. Pediatric Specialist Oncology 3. Pediatric Cancer Hospital 4. Comprehensive Cancer Center
8 WHAT IS BEING DONE TO HELP ELIMINATE PEDIATRIC CANCER? The National Pediatric Cancer Foundation exists for the sole purpose of funding phase 0 and phase 1 clinical research trials testing treatments and cures for different forms of pediatric cancer. Learn a little more about what they do here Big Dreams
9 WHAT MAKES THE NPCF SO DIFFERENT? OUR RESEARCH: THE SUNSHINE PROJECT Brain Tumors: ACTIoN : Adoptive Cellular Therapy following Dose-Intensified Temozolomide in Newly-diagnosed Pediatric High-grade Gliomas LSD1 Inhibitor: Ewing s Sarcoma clinical studies VPLD + Metformin: Relapsed Acute Lymphoblastic Leukemia Sunshine Project Lab: Testing drug combinations Gemcitabine and Nab-Paclitaxel: Recurrent/Refractory Sarcoma Pediatric Total Cancer Care: Blood and tissue banking VIT + Metformin: Relapsed Solid Tumors Sorafenib and Topotecan: Relapsed Solid Tumors
10 RESEARCH PARTNERS RESEARCH INSTITUTES Research conducted in 21 institutions nationwide. Nemours Children s Hospital Johns Hopkins University Connecticut Children s Medical Center Nemours/A.I. dupont Children s Hospital Vanderbilt Children s Hospital Moffitt Cancer Center The Children s Hospital at Montefiore John s Hopkins All Children s Hospital Levine Cancer Institute Children s Hospital of Los Angeles MD Anderson Cancer Center Phoenix Children s Hospital University of Florida Nationwide Children s Hospital Children s National Health System Sylvester Cancer Center, University of Miami University of Kentucky Nemours Children s Clinic Dana Farber Cancer Institute Primary Children s Hospital University of North Carolina
11 WHAT MAKES THE NPCF SO DIFFERENT? OUR FISCAL RESPONSIBILITY We have the highest rankings a charity can receive 100% rating by Charity Navigator for Financial Health and Accountability & Transparency. Less than 1% of thousands of charities rated earn this score. The only cancer related charity in the top 1%.
12 HOW CAN YOU HELP? Become an Ambassador Community educator Media spokesperson Social media champion Advocate for change Volunteer at NPCF events
13 FUNDRAISING OPPORTUNITIES PEER-TO-PEER DIY SIGNATURE EVENTS Bike-a-thon Bake Sale Fitness Challenge School Fundraiser Penny Wars Car Wash Creative Auction
14 To learn more and to sign up to be an ambassador visit: NationalPCF.org/Ambassador David Frazer, CEO: Carleigh DeLuca, Community Engagement:
SHEDDING A LITTLE LIGHT ON THE BIGGER PROBLEM
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