Journal of Ningxia Medical University vacuum sealing drainage VSD VSD VSD VSD VSD VSD EGF. 1 VSD 15cm 10cm 1cm 5cm 10cm 1cm % 4 5.

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1 554 Journal of Ningxia Medical University VSD vacuum sealing drainage VSD VSD VSD VSD epidermal growth factor EGF VSD VSD P < P > 0. VSD VSD P < P > VSD EGF VSD P < VSD VSD EGF R641 A VSD ~ 50h VSD h VSD cm 10cm 1cm 5cm 10cm 1cm 2 VSD VSD ~ ~ 306cm cm 20 cm % VSD VSD ~ ~ VSD 1 300cm VSD VSD cm mmhg

2 6. VSD ~ 2 VSD VSD 1 VSD 1 24h 67 ~ 10d h VSD 1 ~ 2 1 VSD VSD VSD VSD VSD 3 ~ 5 VSD / 72h 480 ~ 600 % /% /% /d /d ml h ~ 360mL h - 1 VSD VSD ~ 10d VSD χ 2 t * * 24h 72h 7d P * t 10% 4μm 2. 2 HE HE VSD VSD VSD 1 1h EGF VSD EGF EGF 0 VSD VSD < 10% 0 Mann - whitneyu = Wilcoxon W = Z = 10% ~ 25% 1 26% ~ 50% P = % ~ 75% 3 75% ~ Fleischmann 4 ~ 7 1 VSD SPSS P < VSD VSD 2 Baharestani M 1 VSD % VSD VSD P < VSD VSD 2 VSD ~ 0. 12mm 2 2 VSD VSD 3 VSD 1 VSD VSD VSDVSD

3 VSD 5 3VSD VSD 1Baharestani MAmjad IBookout K et al. therapy in the management of paediatric woundsclinical review 5 and experiencee J. Int Wound J20096Suppl VSD 2. J. 7 VSD VSD 3. J VSD 4Silberstein J Grabowski J Parsons K et al. Use of a vacuum - assisted device for fournier s gangrenea new VSD P > ParadigmJ. Reviews in Urology VSD VSD 5. J VSD VSD 6SepulvedaGEspindolaMMaureiraM et al. Negative - pressure wound therapy versus standard wound dressing in the treatment of diabetic foot amputation. A randomised controlled trial J. Cir Esp HE c - fos J. 8 EGF Boone BHaspeslagh MBrochez L. Clinical significance of the expression ofc - Ski and SnoNpossibleme- P < VSD diators in TGF - beta resistance in primary cutaneousmelanoma J. J Dermatol EGF 9. J EGF 9 EGF 10Ersin Ozturk Halil Ozguc Tuncay Yilmazlar. The use of vacuum assisted closure therapy in the management of 10 Fournier'sgangreneJ. American journey of surgery VSD

4 6. VSD 557 The Clinical Effect of Vacuum Assisted Closure Dressings for Treatment of Washing with a Large Area of Convection Soft Tissue Defects YAO Zhan - chuan 1 LING Kun 2 MA ke 3 MA Jian - dong 3 ZHANG Xin - ning 3 YANG Fan 3 1. Ningxia Med. Univ. Yinchuan Central Hospital of Guangyuan City in Sichuan Guangyuan Second Affiliated Hospital of Ningxia Med. Univ. Yinchuan AbstractObjective To investigate the clinical effect of vacuum assisted closurevacuum sealing drainage VSDdressings for treatment of washing with a large area of convection soft tissue defects. Methods From September 2008 to April patients with skin and soft tissue defects were randomized. After debridement wounds a simple VSD Simple VSD groupand VSD combined convection flush VSD combined convection flush grouptreatment were performed. The granulation tissue for pathological and immunohistochemical examination were taken before the first skin graft. Hospital stay before surgery skin graftingtotal hospital staysurvival rate of drainage congestiondrainage fluid'culture positive rate of bacteriacontrast epidermal growth factoregfstrength of expression in granulation tissue were compered between two groups. Results Hospital stay before the first skin graft and total hospital stay in simple VSD group were significantly longer than those in the VSD combined convection flush group P < Rate of the VSD combined convection flush group blocked drain was significantly lower than that of the simple VSD group P < immunohistochemistry showed that the expression of EGF in granulation tissue of VSD combined convection flush group was higher than that in the simple VSD group P < Conclusion VSD convective flushing is helpful to reduce the rate of drainage congestion and promote the expression of EGF in granulation tissue. It was conducive to wound healing. Key wordsvsdconvective flushingsoft tissue defectepidermal growth factor 539 Effects of Ginkgo Biloba Extract on Apoptotic Neurons Around the Early Hematoma after Intracerebral Hemorrhage in Rats WANG Deng - ke 1 2 ZHANG Hai - yu 3 SUN Zheng 1 LIU Hai - yang 1 LI Qiang 1 ZHANG Lian - xiang 1 WANG Xiao - jun 1 QIN Yi 1 1. Department of AnatomyHistology and EmbryologyNingxia Medical University Yinchuan Department of Medical College Ningxia Teacher UniversityGuyuan Radiology DepartmentThe People's Hospital of NingxiaYinchuan AbstractObjective To observe early period apoptosis of nerve cells around the hematoma after intracerebral hemorrhage in rats and to discuss effect of Ginkgo biloba extract on the nerve cells around the hematoma. Methods 36 male SD rats were randomly divided into model group and normal group24h treatment groups before surgery 0 h after the treatment group 6h treatment group 24h treatment group. All rats were killed at 72h after operation. Apoptosis was observed around the hematoma by immunohistochemistry. Results HE staining showed that rat caudate nucleus hemorrhage parts had extensive tissue necrosisthe treatment group had narrower site of rat caudate nucleus hemorrhagenecrosis. Bcl - 2Bax and Caspase - 3 protein expression were mild in the normal group and significantly increased in ICHBcl - 2 protein positive cells in preventive treatment group and the treated group were significantly higher than those in the ICH group P < Bax and Caspase - 3 protein positive cells in preventive treatment group and the treated group was significantly lower than those in ICH groupp < Bcl - 2 protein positive cells in preventive treatment group were more than those in the postoperative treatment group and Bax and Caspase - 3 protein cells in preventive treatment group and the treated group was less than those in postoperative treatment groups. Conclusion Ginkgo biloba extract can protect nerve cells around the hematoma after intracerebral hemorrhage in rats inhibit neuronal apoptosis. Preventive medicine showed better results. Key wordsintracerebral hemorrhagenerve cellapoptosisextract of leave Ginkgo Bilobarats

Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

CORRECTION NOTICE Nat. Genet. 42, 759 763 (2010); published online 22 August 2010; corrected online 27 August 2014 Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects