HISTOPATHOLOGY OF THE HEART. I. practical training 3 rd year General Medicine

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1 HISTOPATHOLOGY OF THE HEART I. practical training 3 rd year General Medicine

2 Acute myocardial infarction

3 coagulative necrosis subendocardialy 2 hyperemic layer 3 normal myocard 4 epicard Acute myocardial infarction 4 2 Kopie 2 3

4

5 Acute myocardial infarction

6

7

8 Recent myocardial infarction

9 Recent myocardial infarction

10

11

12 Older myocardial infarction

13 Postinfarction scar of the myocard

14 Postinfarction scar of the myocard

15 Diphtheric myocarditis

16 Diphtheric myocarditis

17 Rheumatic myocarditis

18 Rheumatic myocarditis

19

20

21

22 Bacterial endocarditis 2 4 vegetation 2 atrial endocard 3 papillary muscles 4 myocard 3 3

23 Bacterial endocarditis 2 4 vegetation 2 atrial endocard 3 papillary muscles 4 myocard 3 4

24 Bacterial endocarditis vegetation valve 2 vegetation

25 Bacterial endocarditis vegetation bacterial colonies 2 thrombus 3 erytrocytes and leukocytes

26 bacterial colonies 2 thrombus Bacterial endocarditis vegetation 2

27 Bacterial endocarditis valve 2 2 bacterial colonies 2 valve infiltrated by neutrophils

28 Infiltration by neutrophils Bacterial endocarditis valve

29 Acute fibrinous pericarditis

30 Fibrinous pericarditis copy

31 Epicard 2 Fibrin 3 Myocard Fibrinous pericarditis 2 3

32 Masses of fibrin 2 Epicard Fibrinous pericarditis 2

33 Tuberculous pericarditis

34 Rhabdomyoma of the heart

35 Myxoma copy

36 Myxoma

37 Myxoma 2 spindle and stellar cells 2 stroma with mucus

38 Cardiomyopathy: functional patterns and causes (normal ejection fraction 50-65%) functional pattern ejection fraction of left ventricle mechanism of cardial failure causes dilatated (hypertrophy, dilatation) < 40% systolic dysfunction Idiopathic, alcohol, peripartum, genetic changes, myocarditis, hemochromatosis, chronic anemia, doxorubicin (adriamycin), ssarcoidosis obstructive=hyper trophic (hypertrophy, without dilatation) 50-80% diastolic dysfunction idiopathic, genetic changes, Friedrich ataxia, storage disease, infants of diabetic mothers restrictive (normal size of heart, dilatation) 45-90% diastolic dysfunction idiopathic, amyloidosis, radiation-induced fibrosis Robbins et all: Pathologic basis of disease, Philadelphia, 999

39 Erdheim s cystic medionecrosis

40 Atherosclerosis copy Aorta Conorary artery

41 Atherosclerosis

42 Atherosclerosis

43

44 narrowed lumen of artery 2 atherosclerotic plate in arterial intima 3 arterial wall with fine intima 4 adipose tissue of epicard Atherosclerosis coronary artery

45 Atherosclerosis atherosclerotic plate in arterial intima 2 lumen of artery 3 arterial media 4 arterial adventitia 5 vascularisation of intima 4

46 Atheroclerosis fibrous plaque 2 3 fibrous plate in arterial intima 2 lumen of artery 3 arterial media 4 arterial adventitia 4 3

47 Cholesterol crystals

48 Foamy cells 2 2 nuclei of lipophages 2 adipose substances phagocyted in cytoplasm

49 Intimal capillaries arterial lumen 2 arterial media 3 vascularisation of intima 4 cholesterol crystals 2

50 Atherosclerosis complication 3 copy 2 bleeding in plate 2 atherosclerotic plate 3 poststenotic dilatation of artery

51 Atherosclerosis complication thrombosis copy Arterial lumen filled up with thrombus

52 Atherosclerosis complications

53 Atherosclerosis cholesterol crystals, calcification

54 Nephrosclerosis

55 Nephrosclerosis

56 Nephrosclerosis

57 Polyarteritis nodosa arterial lumen with thrombus 2 deposits of fibrin 3 mixed inflammatory infiltrate

58 Polyarteritis nodosa detail arterial lumen with thrombus 2 deposits of fibrin 3 mixed inflammatory infiltrate

59 Polyarteritis nodosa arterial lumen with thrombus 2 deposits of fibrin 3 mixed inflammatory infiltrate

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