4320 Designs for Health Metabolic Profile plus FA
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1 Ordering Physician: Metametrix 3425 Corporate Way Duluth, GA Accession Number:A Reference Number: Age: 47 Sex: Female Date of Birth: 02/05/1962 Date Collected: 9/2/09 Date Received: 9/3/09 Telephone: Fax: Reprinted: (770) (770) /29/ Designs for Health Metabolic Profile plus FA Urine lipid peroxides have been replaced with 8-OH-2-deoxyguanosine in this report. For over 25 years, Metametrix has been an industry leader providing innovative testing to uncover nutrient insufficiencies, toxicities, and other imbalances that impair healthy body function. Learn more at
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3 Ordering Physician: Metametrix Date Received: 9/3/2009 Date Reported: 9/3/2009 A Sample Report Clinical Symptom - Test Result Correlation Summary B-Vitamin Insufficiency Your test results show indications of less than optimal B-vitamin status. B-vitamins are essential co-factors in a wide spectrum of chemical reactions within the body and are essential for the production of important hormones and neurotransmitters. B-vitamins are the most important vitamin modulators of human biochemistry. Having less than optimal levels for your individual needs may not cause any specific symptoms in some, but may manifest in many people in the following ways: Fatigue and lack of vitality Exercise intolerance Diminished capacity to deal with stress Mood imbalances and sleep disturbance Lack of concentration and memory Blood sugar regulation difficulties Dermatitis and skin disorders Inefficient Fat Metabolism Your test results show a potential inability to efficiently metabolize and burn fats. This may result in: Inability to lose weight Low energy Cognitive decline Inefficient Cellular Energy Production Your test results reveal inefficiency in your cellular energy production. This is a critical process that occurs within all cells and sub-optimal energy production may result in: Fatigue and lack of vitality Exercise intolerance Generalized muscle aches Lack of concentration and memory Overactive Stress Response Your test results suggest a high level of stress and an overactive stress response, which can result in: Anxiety or panic attacks Palpatations (sense of rapid pounding heart beat) Insomnia and sleep disturbance Diminished capacity to deal with stress Mood imbalances Lack of concentration and memory Oxidative Stress Your test results show an increase in oxidative stress. Increases in oxidative stress suggest the need for more dietary antioxidants (i.e., fresh vegetables and fruits) and antioxidant nutritional supplements. Oxidative stress is a biochemical process which may result in: Increased risk for many chronic diseases (i.e., heart disease, stroke, and cancer) Premature aging Omega 3 Fats
4 Your test results show low levels of the beneficial omega-3 fatty acids that are commonly found in the diet in fish/fish oil and flax seed/flax seed oil. Sub-optimal levels of omega-3 fatty acids may result in: Increased body inflammation Increased risk for many chronic diseases (i.e., heart disease, stroke, diabetes and other inflammatory disorders) Dry skin and other skin disorders Omega 6 Fats Your test results reveal elevated levels of the pro-inflammatory fatty acid arachidonic acid (AA) [found in red meat, corn and corn oil] and/or an increase in the ratio of AA to the anti-inflammatory fatty acid eicosapentaenoic acid (EPA). Elevation in AA and/or the AA/EPA ratio may indicate: Increased body inflammation Increased risk for many chronic diseases (i.e., heart disease, stroke, diabetes and other inflammatory disorders) Trans Fats Your test results show increased amount of trans-fats, which are commonly found in processed foods (pastries, baked goods, etc.), fast foods and most hydrogenated vegetable oil products. Elevated trans-fats have been associated with: Increased risk for heart disease, stroke and vascular diseases
5 Ordering Physician: Metametrix Date Received: 9/3/2009 Date Reported: 9/3/2009 A Sample Report Summary of Abnormal Results Findings Intervention Options Metabolic Association B-Vitamin Insufficiency Pyruvate Very High Lipoic Acid, B1, B2, B3, B5 Glucose oxidation Xanthurenate Very High B6 Impaired Tryptophan metabolism Cellular Energy Adipate High Carnitine, B2 Fatty acid oxidation Suberate High Carnitine, B2 Fatty acid oxidation Succinate High CoQ10, B-Complex, Calcium, ATP production Antioxidants Fumarate High CoQ10 ATP production Neural Function Vanilmandelate Very High Evaluate stress issues Epi- & norepinephrine turnover stimulation Quinolinate High Magnesium, Anti-inflammatories, Antioxidants Receptor agonist Detoxification No Abnormality Found Dysbiosis Benzoate High Probiotics or antibiotics Bacterial product Oxidative Stress 8-Hydroxy-2-deoxyguanosine High Antioxidants Free radical damage Polyunsaturated Omega 3 Docosahexaenoic (22:6n3) Very Low Fish oils or extracts Impaired nerve function (esp. the eye) Polyunsaturated Omega 6 Linoleic (18:2n6) Very Low Sunflower or organic canola oil Essential fatty acid; Low membrane fluidity Trans Total C:18 Trans High Avoid hydrogenated oils Hyperlipidemia and degenerative diseases Ratios AA/EPA High Fish oils or extracts Omega-3 insufficiency; Pro-inflammatory status Index of Omega-3 Fatty Acids Low Fish oils or extracts Omega-3 insufficiency A Sample Report
6 This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Organix Profile Methodology: LC/Tandem Mass Spectroscopy, Colorimetric Results are expressed as mcg/mg creatinine. Ranges are for ages 13 and over B-Vitamin Insufficiency Results Percentile Ranking by Quintile 1st 2nd 3rd 4th 5th 95% 20% Pyruvate 40% 60% 80% Reference Interval Pyruvate 6.8 H <= a-ketoglutarate 7.7 <= a-ketoisovalerate 0.19 <= a-ketoisocaproate 0.11 <= a-keto-β-methylvalerate 0.26 <= Xanthurenate 0.80 H <= β-hydroxyisovalerate 6.4 <= Methylmalonate <= Formiminoglutamate 0.1 <= 2.2 Cellular Energy Adipate Adipate 5.3 H <= Suberate 2.0 H <= Ethylmalonate 2.2 <= L-Lactate β-hydroxybutyrate <DL* <= Succinate 18.4 H <= Fumarate 0.66 H <= Malate <= Hydroxymethylglutarate 2.7 <= 5.1 Georgia Lab Lic. Code # CLIA ID# 11D New York Clinical Lab PFI #4578 Florida Clinical Lab Lic. # Page 1 Laboratory Directors: J. Alexander Bralley, PhD Robert M. David, PhD
7 This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Organix Profile Methodology: LC/Tandem Mass Spectroscopy, Colorimetric Results are expressed as mcg/mg creatinine. Ranges are for ages 13 and over Neural Function Percentile Ranking by Quintile 1st 2nd 3rd 4th 5th 95% 20% 40% Vanilmandelate 60% 80% Reference Interval 19 Vanilmandelate 8.0 H Homovanillate Hydroxyindoleacetate Kynurenate 0.8 <= Quinolinate 4.3 H <= Picolinate Citrate Detoxification Citrate Cis-Aconitate Isocitrate Methylhippurate <= Orotate 0.48 <= Glucarate 1.6 <= a-hydroxybutyrate Pyroglutamate , Sulfate 1, <= ,988 Georgia Lab Lic. Code # CLIA ID# 11D New York Clinical Lab PFI #4578 Florida Clinical Lab Lic. # Page 2 Laboratory Directors: J. Alexander Bralley, PhD Robert M. David, PhD
8 This report is not intended for the diagnosis of neonatal inborn errors of metabolism. Organix Profile Methodology: LC/Tandem Mass Spectroscopy, Colorimetric Results are expressed as mcg/mg creatinine. Ranges are for ages 13 and over Compounds of Bacterial Origin Percentile Ranking by Quintile 1st 2nd 3rd 4th 5th 95% 20% Benzoate 40% 60% 80% Reference Interval 34 Benzoate 7.9 H 0.6 <= Phenylacetate <DL* <= Phenylpropionate <DL* <= p-hydroxybenzoate 0.07 <= p-hydroxyphenylacetate 8 <= Indican 33 <= Tricarballylate 0.31 <= ,4-Dihydroxyphenylpropionate <DL* <= D-Lactate 0.6 <= 7.0 Creatinine =200 mg/dl * <DL = less than detection limit Georgia Lab Lic. Code # CLIA ID# 11D New York Clinical Lab PFI #4578 Florida Clinical Lab Lic. # Laboratory Directors: J. Alexander Bralley, PhD Robert M. David, PhD Page 3
9 8-Hydroxy-2 deoxyguanosine - Urine Methodology: LC/Tandem Mass Spectroscopy, Colorimetric What is 8-Hydroxy-2'-deoxyguanosine (8-OHdG)? In its efforts to produce the chemical energy to power your cells and fight infection, your body makes harmful chemicals called free radicals. Sustained inflammatory responses cause increased production of these free radicals. When local antioxidant protection fails to keep free radicals in check, there is threat of damage to cell membranes, enzymes, proteins and DNA. 8-OHdG is a product of oxidative damage by free radicals to DNA, and the 8-OHdG test tells you if you have enough antioxidants in your system. High levels of 8-OHdG are somtimes associated with toxic exposure, cancer, heart disease, diabetes, aging, liver disease, Parkinson's disease, and smoking. Percentile Ranking by Quintile Ranges are for ages 13 and over. Results ng/mg creatinine 1st 2nd 3rd 4th 5th 95% Reference 20% 40% 60% 80% Interval 7 8-Hydroxy-2-deoxyguanosine 7.2 H <= What does my 8-Hydroxy-2'-deoxyguanosine (8-OHdG) result mean? If your 8-OHdG is high, your body is failing to control the rate of formation of free radicals. You can increase your protection by taking vitamins E and C, selenium, beta-carotene, and bioflavonoids. Many products are available that offer combinations of these and other antioxidants that may be beneficial. These test results are not for the diagnosis of disease. They are intended to provide nutritional guidelines to qualified healthcare professionals with full knowledge of patient history and concerns to assist in their design of an appropriate healthcare program. Georgia Lab Lic. Code # CLIA ID# 11D New York Clinical Lab PFI #4578 Florida Clinical Lab Lic. # Page 4 Laboratory Directors: J. Alexander Bralley, PhD Robert M. David, PhD
10 Bloodspot Fatty Acid Profile Results % Total Area Methodology: Capillary Gas Chormotography/Mass Spectrometry Percentile Ranking by Quintile 1st 2nd 3rd 4th 5th 20% 40% 60% 80% 95% Reference Interval Polyunsaturated Omega-3 1 Eicosapentaenoic (EPA) (20:5n3) Docosahexaenoic (DHA) (22:6n3) L Polyunsaturated Omega-6 3 Linoleic (LA) (18:2n6) 8.8 L 4 Gamma Linolenic (GLA) (18:3n6) Dihomogamma Linolenic (DGLA) (20:3n6) Arachidonic (AA) (20:4n6) Trans 7 Total C:18 Trans Fatty Acids 0.64 H 0.63 <= 0.86 Ratios 8 LA/GLA (Desaturation efficiency) AA/EPA (Eicosanoid Series 2/3) 24.4 H 10 EPA/DGLA (Eicosanoid Series 3/1) Index of Omega-3 Fatty Acids (EPA + DHA %) 0.49 L > 0.44 Sears, B. Toxic Fat: When Good Fat Turns Bad. 1st ed. Nashville, TN: Thomas Nelson; Harris, WS. Omega - 3 fatty acids and cardiovascular disease: A case for omega-3 index as a new risk factor. Pharmacological Research 2007; 55:
11 These test results are not for the diagnosis of disease. They are intended to provide nutritional guidelines to qualified healthcare professionals with full knowledge of patient history and concerns to assist in their design of an appropriate healthcare program. Georgia Lab Lic. Code # CLIA ID# 11D New York Clinical Lab PFI #4578 Florida Clinical Lab Lic. # Page 5 Laboratory Directors: J. Alexander Bralley, PhD Robert M. David, PhD Supplement Recommendation Summary The Designs for Health Comprehensive Metabolic Profile results may be used, along with full knowledge of this patient's medical history and concerns, to help healthcare professionals create an individually optimized nutritional support program. The summary table below is based strictly on the results from this test. It shows estimates of nutrient doses that may help to normalize nutrient-dependent metabolic functions. All amounts are adult doses that should be adjusted for children according to body weight and indication of need. These supplement suggestions are based solely on the objective test markers and may serve as a foundational program to optimize metabolic function and address any observed deficiencies. These suggestions may be used in place of supplements the patient was taking at the time the testing was initiated. However, it should not preclude this patient from taking additional supplements as recommended by his/her healthcare provider for other health conditions or requirements unique to the individual. Recommendations may appear because of secondary associations that are not stated in the Summary section on the first page. Foundational Metabolic Support DFH Complete Multivitamin Vitamin and Mineral Recommendations B-Supreme Magnesium Malate Chelate Q-Avail 100 Amino Acid Recommendations Either (1) Carnitine Tartarate Powder or (2) CarniClear Fatty Acid Recommendations Either (1) OmegaAvail TG 1000 Softgels or (2) OmegaAvail TG 1000 Liquid (avoid arachidonic acid rich foods) Combination Product Recommendations CatecholeCalm (consider stress-reduction techniques and eliminate caffeine) Inflammatone Lipoic Acid Supreme Ultimate Antioxidant-Full Spectrum 3 caps daily 1 twice daily 2/day 1 cap/day If (1), then 1/2 tsp/day or if (2), then 1 tsp/day If (1) then 2 soft gels twice daily or if (2) then 2 tsp twice daily 3 caps/day 2 caps twice daily 1 cap daily 3 soft gels/day If orotate is elevated, amino acid supplementation may be contraindicated, except for arginine. These guidelines are intended as a starting point for the clinician who requested the test and are based only on the laboratory results included in this report. Final recommendations should be implemented by the clinician with consideration of medical history and current clinical observations. These tests are not intended for the diagnosis or treatment of specific disorders.
4315 NY Designs for Health Metabolic Profile
Ordering Physician: Metametrix Staff & Family 3425 Corporate Way Duluth, NY 30096 Accession Number:A0909030008 Reference Number: Age: 47 Sex: Female Date of Birth: 02/05/1962 Date Collected: 9/2/09 Date
0091 Organix Comprehensive Profile - Urine
Accession #: Order #: Reference #: Patient: Date of Birth: Age: Sex: Date Collected: Date Received: Telephone: Fax: Organix Interpretation Organix Interpretive Guide is downloadable at: www.metametrix.com/files/test-menu/interpretive-guides/organix-ig.pdf
0291 Organix Basic Profile Summary of abnormal results:
Ordering Physician: 250200-274226 Reference Number: Age: 57 Sex: F Date of Birth: 12/25/1949 Date Collected: 11/18/07 Date Received: 11/18/07 Report Date: Telephone: Fax: Reprinted: 12/5/07 7704465483
0091 Organix Comprehensive Profile - Urine
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/2001
4146 Women's Health Profile
Ordering Physician: Metametrix 1234 Main St. Anywhere, GA 30096 Reference Number: Age: 50 Sex: Female Date of Birth: 02/05/1962 Date Collected: 6/12/12 Date Received: 6/13/12 Report Date: Telephone: Fax:
0291 Organix Basic Profile - Urine
Accession #: Order #: Reference #: Patient: G1234567 Date Collected: Date Received: Date of Report: 04/03/2012 Date of Birth: 02/05/1962 Telephone: 7704464583 Ordering Physician: Age: Sex: 50 Female Fax:
0091 Organix Comprehensive Profile Summary of abnormal results:
Ordering Physician: 255252-279741 Via Borin 48 31100 Treviso Number: Age: 43 Sex: F Date of Birth: 03/01/1964 Date Collected: 12/12/07 Date Received: 12/17/07 Telephone: Fax: Summary of abnormal results:
Essential Amino Acids
3425 Corporate Way Duluth, GA 30096 Patient: SAMPLE PATIENT DOB: Sex: MRN: 3100 ION Profile - Blood / Urine Amino Acids 20 Profile - Plasma Methodology: High Performance Liquid Chromatography s: Ages 13
Patient Guide. Comprehensive Metabolic Profile Basic plus FA Profile Basic Metabolic Profile. Laboratory Evaluations by
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3425 Corporate Way Duluth, GA 30096 3102 ION Profile with Amino Acids 40 - Blood/Urine Amino Acids 40 Profile - Plasma Methodology: High Performance Liquid Chromotography s: Ages 13 and over. Limiting
0410 Triad Bloodspot Profile
Accession Number: Order Number: Reference Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0410 Triad Bloodspot Profile This report contains the following:
0490 ION with Amino Acids 40 Profile
Accession Number: Order Number: Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0490 ION with Amino Acids 40 Profile Amino Acids 40 Profile -
0490 ION with Amino Acids 40 Profile
Metametrix 1234 Main St. Anywhere, GA 30096 Accession Number: Order Number: G1234567 Number: Patient: Age: 51 Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: Sex: 4/3/13 Date Received:
0290 Cardio/ION Profile
Accession Number: Order Number: Reference Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0290 Cardio/ION Profile Date Reported: Cardiovascular
0490 ION with Amino Acids 40 Profile
Accession Number: Order Number: Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0490 ION with Amino Acids 40 Profile Amino Acids 40 Profile -
0290 Cardio/ION Profile
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Accession Number: Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax:
0400 Triad Profile. Accession Number: Order Number: Reference Number: Patient: Age:
Accession Number: Order Number: Reference Number: Patient: Age: Sex: Date of Birth: Date Collected: Date Received: Report Date: Telephone: Fax: Reprinted: Comment: 0400 Triad Profile This report contains
0400 Triad Profile. Metametrix Corporate Way Duluth, GA 30096
3425 Corporate Way Duluth, GA 30096 Accession Number: Reference Number: Patient: Age: 48 Sex: Female Date of Birth: 02/05/1962 Date Collected: 12/7/10 Date Received: 12/8/10 Report Date: Telephone: Fax:
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