0410 Triad Bloodspot Profile
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1 Accession Number: Order Number: Reference Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0410 Triad Bloodspot Profile This report contains the following: 1. Laboratory data Organix Comprehensive Profile Amino Acids 20 - Blood Spot IgG Bloodspot Foods (30 Antigens) 2. Triad Profile Analyte Pattern Analysis To view your online Food Reaction Patient Guide, please visit our website at and select the Downloads tab on the top row navigation.
2 Date Reported: 0410 Triad Bloodspot Profile Summary of abnormal results: Findings Intervention Options Metabolic Association Fatty Acid Metabolism Carbohydrate Metabolism Energy Production Markers Cis-Aconitate Very Low Free-form amino acids Amino Acid insufficiency Isocitrate Very Low Free-form amino acids Amino Acid insufficiency B-Complex Vitamin Markers Methylation Cofactor Markers Neurotransmitter Metabolism Markers Oxidative Damage and Antioxidant Markers Detoxification Indicators Pyroglutamate Very Low Free-form amino acids Amino Acid insufficiency Bacterial - General L. acidophillus/general bacteria Clostridial species Yeast/Fungal Essential Amino Acids Number of abnormal aminos 2 Determine candidacy for amino acids Failure to utilize Neuroendocrine Metabolism Ammonia/Energy Metabolism Number of abnormal aminos 1 Determine candidacy for amino acids Failure to utilize Food Antibody Reactions (No. of foods) A Sample Report
3 Organix Comprehensive Profile - Urine Ranges: Ages 13 and over. Nutrient Markers Results mcg/mg creatinine Date Reported: Methodology: LC/Tandem Mass Spectroscopy, Colorimetric 95% Reference Interval Fatty Acid Metabolism (Carnitine & B2) Adipate 1.1 <= Suberate 0.4 <= Ethylmalonate 0.9 <= 6.3 Carbohydrate Metabolism (B1, B3, Cr, Lipoic Acid, CoQ10) Pyruvate <DL* <= L-Lactate β-hydroxybutyrate <DL* <= 9.9 Energy Production (Citric Acid Cycle) (B comp., Q10, Amino acids, Mg) Citrate Cis-Aconitate 13 L Isocitrate 25 L a-ketoglutarate 12.2 <= Succinate 2.7 <= Fumarate <= Malate 0.6 <= Hydroxymethylglutarate 1.4 <= 5.1 B-Complex Vitamin Markers (B1, B2, B3, B5, B6, Biotin) a-ketoisovalerate 0.10 <= a-ketoisocaproate 0.06 <= a-keto-β-methylvalerate 0.10 <= Xanthurenate 0.14 <= β-hydroxyisovalerate 1.5 <= 11.5 Methylation Cofactor Markers (B12, Folate) Methylmalonate 0.4 <= Formiminoglutamate <DL* <= 2.2 Page 1
4 Ordering Physician: Organix Comprehensive Profile - Urine Ranges: Ages 13 and over. Cell Regulation Markers Results mcg/mg creatinine Date Reported: Methodology: LC/Tandem Mass Spectroscopy, Colorimetric 95% Reference Interval Neurotransmitter Metabolism Markers (Tyrosine, Tryptophan, B6, antioxidants) 22 Vanilmandelate Homovanillate Hydroxyindoleacetate Kynurenate 0.7 <= Quinolinate 1.2 <= Picolinate Oxidative Damage and Antioxidant Markers (Vitamin C and other antioxidants) 28 p-hydroxyphenyllactate <= Hydroxy-2-deoxyguanosine 4.0 <= 7.6 (Units for 8-Hydroxy-2-deoxyguanosine are ng/mg creatinine). Toxicants and Detoxification Detoxification Indicators (Arg, NAC, Met, Mg and antioxidants) Methylhippurate <DL* <= Orotate <DL* <= Glucarate 1.9 <= a-hydroxybutyrate 0.1 <= Pyroglutamate 7 L , Sulfate ,988 Page 2
5 Organix Comprehensive Profile - Urine Ranges: Ages 13 and over. Results mcg/mg creatinine Date Reported: Compounds of Bacterial or Yeast/Fungal Origin Methodology: LC/Tandem Mass Spectroscopy, Colorimetric 95% Reference Interval Bacterial - general Benzoate 0.6 <= Hippurate 104 <= 1, Phenylacetate <DL* <= Phenylpropionate <DL* <= p-hydroxybenzoate 0.5 <= p-hydroxyphenylacetate 8 <= Indican 46 <= Tricarballylate 0.31 <= 1.41 L. acidophilus / general bacterial D-Lactate 0.7 <= 4.3 Clostridial species 45 3,4-Dihydroxyphenylpropionate <DL* <= 0.05 Yeast / Fungal D-Arabinitol Creatinine =220 mg/dl 26 <= 73 * <DL = less than detection limit ** >LIN = greater than linearity limit Page 3
6 Date Reported: Bloodspot Amino Acids 20 Profile Methodology: ION Exchange HPLC Ranges: Ages 13 and over Essential Amino Acids Results µmol/l 95% Reference Interval Limiting Amino Acids Lysine Methionine Tryptophan H Branched Chain Amino Acids Isoleucine Leucine Valine Other Essential Amino Acids Phenylalanine Histidine Threonine Conditionally Essential Amino Acids 10 Arginine 11 Taurine 12 Glycine 13 Serine H Page 4
7 Date Reported: Bloodspot Amino Acids 20 Profile Methodology: ION Exchange HPLC Ranges: Ages 13 and over Functional Categories Vascular Function 14 Arginine 15 Taurine Results µmol/l Neurotransmitters and Precursors 16 Phenylalanine 17 Tyrosine 18 Tryptophan 19 Glutamic Acid 20 Taurine H H % Reference Interval Sulfur Amino Acids (Glutathione - related) 21 Methionine 36 H 22 Taurine 311 H Urea Cycle and Ammonia Detoxification Arginine Citrulline Ornithine Glutamine 527 H Asparagine Aspartic Acid 175 Ratios Phenyalanine/Tyrosine Glutamic Acid/Glutamine Tryptophan/LNAA* *Large neutral amino acids (Leu+Ile+Val+Phe+Tyr) <= Page 5
8 Date Reported: Allergix Bloodspot IgG4 Food Antibodies 30 Profile Methodology: ELISA Foods to Avoid Negative Mild Moderate Severe +1 and and Almond Aspergillus Beef Cantaloupe Cashew Chicken Corn Crab Egg, Whole Garlic Lobster Milk Mustard Seed Oat Orange Pea, Green Peanut Pinto Bean Pork Rice Salmon Shrimp Soybean Strawberry Sunflower Tomato Tuna Turkey Walnut Wheat Responses reflect IgG levels measured by ELISA with standardized food extracts. The assay yields semi-quantitative antibody concentrations for each food. The concentration readings are categorized into four reaction levels (Negative, Mild, Moderate, or Severe) corresponding to semi-quantitative responses (0/1, +1, +2, +3, +4, or +5), based on relative absorbance readings. The likelihood of adverse reactions to a given food increases as the response level for that food becomes more positive. Page 6
9 Triad Profile Analyte Pattern Analysis A multi-analyte report can provide greater insight about health risks and special nutrient needs. Patterns of abnormalities can reinforce the degree of significance indicated by a single measurement. Analytes from the various profiles in the Triad report are combined below into categories associated with clinical/metabolic conditions. The categories included cover the most common areas of concern relevant to these profiles. Above each thermometer are listed the analytes used to calculate the degree of significance. An X appears when the patient result is in the fifth quintile of the population. An additional H or L next to an analyte indicates that the patient result is outside the reference limit or interval for that analyte. The thermometer advances to the right as the number and severity of relevant abnormalities increases. The longer the filled bar, the greater the degree of significance or likelihood that a health threat may exist in that category. The preceeding laboratory reports provide the detail upon which these thermometers are based. Fatigue (Mitochondrial Impairment) Isoleucine Leucine Phenylalanine Adipate Suberate akg Succinate Malate Xanthurenate MeMalonate FIGLU Mental/Emotional Tryptophan Tyrosine Xanthurenate MeMalonate FIGLU Quinolinate VMA 5-HIA HVA Intestinal Hyperpermeability (Leaky Gut) Positive IgG scores of 1+ or higher were found for 0 foods. Low significance Digestive Insufficiency Histidine Isoleucine Leucine Lysine Methionine Threonine Valine MeMalonate Pyruvate akbmeval Glutamine Page 7
10 Triad Profile Analyte Pattern Analysis Toxic Exposure 2-MeHipp Glucarate Sulfate Orotate Citrate Cis-Aconitate Isocitrate Quinolinate Mitochondrial Functional Impairment Adipate Suberate Ethylmalonate Pyruvate L-Lactate β-hb Succinate Fumarate Malate Amino Acid Insufficiency Detoxification Capacity Methionine Glycine Taurine Sulfate Pyroglutamate L X HMG Arginine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Threonine Tryptophan Valine akg Succinate Sulfate Gut Dysbiosis D-Arabinitol PhAc PhProp phphac AHB Indican Tricarb D-Lactate 3,4-DHPP H X Low significance Page 8
11 Triad Profile Analyte Pattern Analysis Methylation Xanthurenate MeMalonate FIGLU Abbreviatio 2-MeHipp 5-HIA 8-OhdG AHB akbmeval AKG akicap akival BHB BHiVal 3,4-DHPP FIGLU Analyte Name 2-Methylhippurate 5-Hydroxyindoleacetate 8-Hydroxy-2-deoxyguanosine a-hydroxybutyrate a-keto-ß-methylvalerate a-ketoglutarate a-ketoisocaproate a-ketoisovalerate ß-Hydroxybutyrate ß-Hydroxyisovalerate 3,4-Dihydroxyphenylpropionate Formiminoglutamate Abbreviation HVA HMG IgG MeMalonate PhAc PhProp phbenz phphac phphlac Tricarb VMA Analyte Name Homovanillate Hydroxymethylglutarate Immunoglobulin G* Methylmalonate Phenylacetate Phenylpropionate p-hydroxybenzoate p-hydroxyphenylacetate p-hydroxyphenyllactate Tricarballylate Vanilmandelate * Thermometers are affected when more than nine foods cause reactions of +1 or higher. Page 9
12 Customized Vitamin-Mineral Formula With knowledge of a patient's full medical history and concerns, the Triad Profile laboratory results may be used to help create an individually optimized nutritional support program. Based strictly on the results from this test, the summary table below shows estimates of nutrient doses that may help to normalize nutrient-dependent metabolic functions. Customized Vitamin and Mineral Formulation Nutrients listed in this section are normally contained in a multi-vitamin preparation. "Base" amounts may be used to ensure health even when no abnormalities are found. Customized preparations of the multi-vitamin/mineral formula shown below may be produced by compounding pharmacies. Daily Amounts Base Units Added Vitamin A* 2500 IU B-Carotene* 5500 IU Vitamin C 250 mg Vitamin D* 400 IU Vitamin E (Mixed Tocopherols) 100 IU Vitamin K* 100 mcg Thiamin (B1) 5 mg Riboflavin (B2) 5 mg Niacin (B3) 25 mg Pyridoxine (B6) 15 mg Folic Acid (or 5-Methyl-THF) 400 mcg Vitamin B12 50 mcg Biotin 100 mcg Pantothenic Acid (B5) 25 mg Calcium citrate 500 mg Iodine* 75 mcg Magnesium 250 mg Zinc* 15 mg Selenium 100 mcg Copper 1 mg Manganese* 5 mg Chromium 200 mcg Molybdenum* 25 mcg Boron* 1 mg * Nutrients with an asterisk are not modified based on the Triad test results. MM01 Page 10
13 Other Items Indicated for individual supplementation Various conditionally essential nutrients and other potentially beneficial interventions appear in this section only if relevant abnormalities are present. These ingredients are not included in the customized vitamin formula on the previous page. Amino acids listed on this page result from functional markers of individual amino acid insufficiency and do not reflect amino acids measured in plasma. Any amino acids that appear may be needed in addition to the customized amino acid formula on the following page. Item Amount Page 11
14 Customized Free-Form Amino Acids The table below shows a customized amino acid formula based on the results of your laboratory profile. The formula is optimized by adding amounts shown in the Grams Added column according to the relative positions of results found. Directions: Adults mix 1 and 1/2 measuring teaspoon (5g) in juice or water 2 times daily between meals as a dietary supplement, or as directed by a health care provider. Children under 12 years old: 3/4 teaspoon 1-2 times daily between meals. Children under 5 years old: Use 1/4 teaspoon, 1-3 times daily; adjust for body weight. Grams Added % of Formula Active mg/day L-Arginine HCl (80% active) L-Histidine HCl (74% active) L-Isoleucine L-Leucine ,164 L-Lysine HCl (80% active) L-Methionine L-Phenylalanine ,164 Taurine L-Threonine L-Tryptophan L-Valine ,020 Pyridoxal-5-phosphate Alpha-ketoglutaric acid Total grams added 1 Base Formula amount 299 Total Weight 300 L-5-Hydroxytryptophan This formula is intended to optimize essential and conditionallly essential amino acid intake. Other non-essential amino acids can be produced in human tissues. Pyridoxal-5-phosphate (an active form of vitamin B6) and alpha-ketoglutaric acid are key factors needed for the body's utilization of amino acids. The formula may be ordered as a powder that dissolves easily in beverages or may be added to foods such as applesauce. Other forms of supplemental dietary protein or amino acids may need to be restricted while using your customized formula. If enhanced energy levels prevent sleep, avoid bedtime use. This formula is provided as a starting point that may guide decisions about medical treatment based on the test results. It is derived only from the laboratory results included in this report. Final recommendations should be based on consideration of the patient's medical history and current clinical condition. Page 12
0091 Organix Comprehensive Profile - Urine
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Ordering Physician: Accession #: Reference #: Patient: Date of Birth: Age: Sex: Reprinted: 07/04/2001
0091 Organix Comprehensive Profile - Urine
Accession #: Order #: Reference #: Patient: Date of Birth: Age: Sex: Date Collected: Date Received: Telephone: Fax: Organix Interpretation Organix Interpretive Guide is downloadable at: www.metametrix.com/files/test-menu/interpretive-guides/organix-ig.pdf
0091 Organix Comprehensive Profile Summary of abnormal results:
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0400 Triad Profile. Accession Number: Order Number: Reference Number: Patient: Age:
Accession Number: Order Number: Reference Number: Patient: Age: Sex: Date of Birth: Date Collected: Date Received: Report Date: Telephone: Fax: Reprinted: Comment: 0400 Triad Profile This report contains
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3425 Corporate Way Duluth, GA 30096 Accession Number: Reference Number: Patient: Age: 48 Sex: Female Date of Birth: 02/05/1962 Date Collected: 12/7/10 Date Received: 12/8/10 Report Date: Telephone: Fax:
0291 Organix Basic Profile - Urine
Accession #: Order #: Reference #: Patient: G1234567 Date Collected: Date Received: Date of Report: 04/03/2012 Date of Birth: 02/05/1962 Telephone: 7704464583 Ordering Physician: Age: Sex: 50 Female Fax:
0291 Organix Basic Profile Summary of abnormal results:
Ordering Physician: 250200-274226 Reference Number: Age: 57 Sex: F Date of Birth: 12/25/1949 Date Collected: 11/18/07 Date Received: 11/18/07 Report Date: Telephone: Fax: Reprinted: 12/5/07 7704465483
0490 ION with Amino Acids 40 Profile
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4146 Women's Health Profile
Ordering Physician: Metametrix 1234 Main St. Anywhere, GA 30096 Reference Number: Age: 50 Sex: Female Date of Birth: 02/05/1962 Date Collected: 6/12/12 Date Received: 6/13/12 Report Date: Telephone: Fax:
Essential Amino Acids
3425 Corporate Way Duluth, GA 30096 Patient: SAMPLE PATIENT DOB: Sex: MRN: 3100 ION Profile - Blood / Urine Amino Acids 20 Profile - Plasma Methodology: High Performance Liquid Chromatography s: Ages 13
0490 ION with Amino Acids 40 Profile
Metametrix 1234 Main St. Anywhere, GA 30096 Accession Number: Order Number: G1234567 Number: Patient: Age: 51 Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: Sex: 4/3/13 Date Received:
0290 Cardio/ION Profile
Accession Number: Order Number: Reference Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0290 Cardio/ION Profile Date Reported: Cardiovascular
4315 NY Designs for Health Metabolic Profile
Ordering Physician: Metametrix Staff & Family 3425 Corporate Way Duluth, NY 30096 Accession Number:A0909030008 Reference Number: Age: 47 Sex: Female Date of Birth: 02/05/1962 Date Collected: 9/2/09 Date
Essential Amino Acids
3425 Corporate Way Duluth, GA 30096 3102 ION Profile with Amino Acids 40 - Blood/Urine Amino Acids 40 Profile - Plasma Methodology: High Performance Liquid Chromotography s: Ages 13 and over. Limiting
0490 ION with Amino Acids 40 Profile
Accession Number: Order Number: Number: Patient: Age: Sex: Date of Birth: Date Collected: Report Date: Telephone: Fax: Reprinted: Comment: 0490 ION with Amino Acids 40 Profile Amino Acids 40 Profile -
0010 Amino Acids 40 Profile - Plasma
Accession #: Order #: G1234567 Date Collected: Date Received: 01/22/2013 Reference #: Patient: Date of Birth: 02/05/1962 Date of Report: Telephone: 7704464583 Ordering Physician: 1234 Main St. Anywhere,
0290 Cardio/ION Profile
3425 Corporate Way Duluth GA 30096 USA 770.446.5483 Fax: 770.441.2237 www.gdx.net/www.metametrix.com Accession Number: Number: Patient: Age: Date of Birth: Date Collected: Report Date: Telephone: Fax:
4320 Designs for Health Metabolic Profile plus FA
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0010 Amino Acid Analysis - 40 Plasma
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