4/16/2009. Gabler Laboratory Research Program. Long chain n-3 Fatty Acids, Fetal Programming and Swine. My Background. Swine Research Areas
|
|
- Calvin Nicholson
- 5 years ago
- Views:
Transcription
1 /1/9 Gler Lortory Reserch Progrm Nichols Gler Venktesh Mni (PhD. student) Emily Kuntz (BSc. student) Mrth Jeffrey (L. Mnger) Deprtment of Animl Sciences Iow Stte University L Troe University B. Agriculturl Science Ph.D. My Bckground Purdue nd Iow Stte University Postdoctorl reserch ssocite Iow Stte University Fll 8 Animl Science fculty 3%Reserch 7% Reserch Feed efficiency Swine Reserch Ares Mternl nutrition nd fetl progrmming Gstrointestinl test trct Helth Nutrient trnsport Endotoxin trnsport Mycotoxin trnsport Skeletl muscle protein synthesis nd degrdtion Swine Residul Feed Intke (RFI) RFI: The difference etween ctul feed intke nd tht predicted on the sis of requirements for production nd mintennce of ody weight (Feed consumed over nd ove expected requirements for production nd mintennce) Yorkshire Pigs Control (rndom reed) Select (low RFI, high efficiency selection reed) AFRI-USDA 9 Growth nd Nutrient Utiliztion Grnt Aim #1: Evlute dietry nutrient retention, energy lnce, protein nd len ccretion rtes in finisher pigs selected for low RFI Aim #: Determine the extent to which ppetite regultory peptides contriute t to ltered feeding ehvior, reduce feed intke nd enhnces feed efficiency in low RFI pigs Aim #3: Identify key metolite, srcoplsmic nd mitochondril proteins tht correlte with improved skeletl muscle metolism nd ccretion in finisher pigs selected for low RFI Long chin n-3 Ftty Acids, Fetl Progrmming nd Swine 1
2 /1/9 Suckling nd Wenling Pig Chllenges Hypothesis The neworn experiences life-thretening situtions which re excerted y its physicl wekness nd low energy reserves Mternl diet influences the ftty cid profile of milk nd the piglet Birth Wening % of totl clories FAT PROTEIN CARBOHYDRATE Incresing the n-3 ftty cid content of piglet tissues vi the mternl diet will improve intestinl morphology nd glucose uptke t the wening trnsition Gler et l. (7) Journl of Nutrition 137(11): Gler et l. (9) Journl of Nutritionl Biochemistry (1): 17-5 Sow Milk Ftty Acid Profile n-3 Ftty Acid Concentrtions in Piglet Smll Intestinl Tissue CONT PFO (g/1g totl ftty cid) α-la.1.57 EPA..7 DPA..7 DHA.. EPA CONT PFO DHAGF DHA CONT PFO DHAGF Totl n Totl n PFO = Protected Fish Oil rich in DHA nd EPA 1.. CONT PFO DHAGF Different letters within rows represent significnt differences etween tretments (P<.5) Mens±SEM, n = milk smples from different sows/tretment Different letters, represent significnt differences etween tretments (P<.5) Mens±SEM, n = piglets/tretment Jejunum Morphology ws not Altered y n-3 Ftty Acids Intestinl Glucose Trnsport CONT PFO SEM P-vlue Villus height (μm) Crypt depth (μm) Villus:Crypt rtio Ussing Chmers used to mesure ctive glucose trnsport Chnge in current cross the intestine High chnge in current = Incresed Active Glucose Trnsport Mucos uffer solution seros uffer solution Mucos Seros
3 /1/9 n-3 Ftty Acids Increse Intestinl Glucose Trnsport t Wening Intestinl Glucose Trnsporters Active glucose uptke Cont/Cont PFO/PFO PFO/Cont Cont/PFO High Intestinl Glucose ENTEROCYTE Lumen N+ Glucose N+ SGLT1 GLUT Blood strem Apicl memrne Sodiumdependent Glucose Trnsporter (SGLT1) Bsolterl Glucose Trnsporter (GLUT) GLUT Different letters, represent significnt differences etween tretments (P<.5) Mens±SEM, n = 5 piglets/tretment Apicl memrne MUCOSAL Bsolterl memrne SEROSAL n-3 Ftty Acids Increse Glucose Trnsporter Protein Where to From Here? Memrne GLUT Aritrry Units Cont/ContPFO/PFO Cont/PFOPFO/Cont SGLT1 (Totl) 35 ts Aritrry Unit Cont/Cont PFO/PFO Cont/PFO PFO/Cont Wht is hppening to mino cid trnsporter? Link etween AMPK nd ATPse? AMPK or ATPse knockdown kd studies in pig enterocytes Do fll off pigs hve different nutrient trnsport cpcities thn rigorous littermtes? Different letters represent significnce (P<.5) Innte Immunity nd n-3 Ftty Acids Toll like receptor (Tlr) ntgonized y n-3 ftty cids (Gler et l., 8) n-3 ftty cids re le to lock LPS trnsmemrne signling (Chu et l., 1999) Anti-inflmmtory properties Toll like receptor signling pthwy LPS CD1 TLR MD Myd88 IRAK TRAF TRAF IKKβ IκBαNFκB TNF,IL IκBα NFκB NFkB pthwy regultes inflmmtion Required for innte immune responses NFkB IL TNFα Pro-inflmmtory cytokine production nd rective oxygen species (ROS) 3
4 /1/9 n-3 Ftty Acids Attenute the Ferile Response to LPS Questions We Are Asking? emperture (C) Rectl te Time P< Tretment P=.8 d Tretment*Time P<.1 1. d c c c.5 c c c ccc (Sline) ccc (LPS). ppp (LPS) 39.5 pcc (LPS) Role of Tlr, CD1? Mycotoxin? Dirrhe, E. coli F18 nd K88 in wened pigs? Endotoxin nd its impct on nutrient trnsport? Cn n-3 ftty cids ttenute endotoxin trnsfer cross the intestinl mucos? Hours post chllenge Pigs (3.5 ± 3. kg) were chllenged with 1 μg/kg BW of lipopolyscchride (LPS) or sline y intrmusculr injection. n = 1 pigs per tretment. Intestinl Endotoxin nd Mycotoxin Trnsport The trnsepithelil trnsport of fluorescein isothiocynte leled LPS (FITC-LPS) or Afltoxin B1 nd B The effects of ftty cids nd fier on pig intestinl endotoxin nd mycotoxin trnsport Mounted jejunum smples from pigs re mounted into Ussing chmers The mounted intestines will e incuted with FITC-LPS or mycotoxin on the mucosl side Aliquots of medium from the mucosl nd serosl sides will e tken t 15 min intervls for up to 1 min nd the luorescence of the liquots determined in plte reder The pprent permetion coefficient (Ppp) will e clculted using the following eqution: Ppp = dq/(dt x A x C ) Where dq/dt is the trnsport rte nd corresponds to the slope of the regression line, C is the initil concentrtion in the donor chmer, nd A is the surfce re of the tissue EMILY KUNTZ INDEPENDENT RESEARCH PROJECT (ANS 9) DEPARTMENT OF ANIMAL SCIENCES IOWA STATE UNIVERSITY Bckground Endotoxin The digestive trct is mjor entry point for pthogens The intestines form mjor physicl rrier to pthogens from entering circultion nd then ctivting the cquired nd innte immune systems Bcteri (endotoxin) Fungl mycotoxin Other toxic compounds Immune chllenges (cute or chronic) directly impct the growth nd reproductive performnce of swine Endotoxin cn e derived from grm negtive cteri such s E. coli nd Slmonell Endotoxin ctivtes receptor medited inflmmtory processes Endotoxin is sored y the intestine Prcellulr trnsport through the tight junctions Trnscellulr pthwy vi pssive diffusion through the enterocyte (sorptive cells) This sorption of the gut-derived cteri endotoxin plys n importnt role in the development of intestinl dysfunction, inflmmtion, peripherl tissue ctolism nd metolic disese
5 /1/9 Mycotoxin Diet, Endotoxin nd Mycotoxin Trnsport The mycotoxin is commonly found in cerels nd cn cuse: Vomiting Porcine pulmonry edem Anorexi Slow growth rtes Necrosis Decresed protein synthesis Dirrhoe Mlsorption of nutrients Reduced reproductive performnce Mortlity Compromised immunity in pigs Mycotoxin Afltoxin B1 & B Deoxynivlenol (Vomitoxin) Zerlnone Tricothecene Do different dietry compound effect the rte of trnsport of endotoxin nd mycotoxin? Dietry ftty cids Sturted ftty cids (coconut oil) Unsturted ftty cids (corn oil, olive oil, veg. oil, fish oil) Dietry fier Strch Cellulose Citrus pectin FITC-LPS Trnsport nd Ftty Acids (1) FITC-LPS Trnsport nd Ftty Acids () FITC C-LPS (rfu) Control Coconut Fish Olive Oil Cod Liver Vegetle Ppp (cm/min) c c FITC-LPS (rfu) Control CornOil Cod CLA Ppp (cm/min) c Control Corn Oil Cod Liver CLA Different letters represent significnce (P<.5) Different letters represent significnce (P<.5) FITC-LPS Trnsport nd Fier Mycotoxin FITC-LPS (rfu) Control Pectin Strch Cellulose Ppp (cm/min) FITC-LPS (rfu) F Control CornOil CodLiver CLA 1 Ppp (cm/min) 1 8 Different letters represent significnce (P<.5) Control Pectin Strch Cellulose Different letters represent significnce (P<.5) Control Corn Oil Cod Liver CLA 5
6 /1/9 Summry Conclusion Sturted fts increses endotoxin trnsport rtes n-3 ftty cids (fish oils) decrese endotoxin trnsport Conjugted linoleic cid ugments oth intestinl endotoxin nd mycotoxin trnsport Potto strch ids in the trnsport of endotoxin cross the intestine, while cellulose decreses this trnsport Dietry ft differentilly lters fltoxin trnsport Dietry compounds could e utilized to decrese the mounts of endotoxin nd mycotoxin trnsport cross the intestine Better understnding of how different dietry compounds influence endotoxin nd mycotoxin could led to etter diet formultions nd improved growth nd reproductive performnce in swine Further reserch needs to confirm this hypothesis
Abstract ABSTRACT #69. Abstract. Introduction & Methods. Methods & Results. Results. Results & Conclusions
Effects of dietry β-glucn on Growth Performnce, Dirrhe, nd Gut Permeility of Wening Pigs Experimentlly Infected with Pthogenic E. coli Kwngwook Kim, Amy Ehrlich, Vivin Perng, Jennifer Chse, Helen Ryould,
More informationIntroduction. Lance Baumgard. Introduction con t. Research Emphasis at AZ. Teaching and Advising. Research Emphasis at ISU 4/29/2010
Introduction Lnce Bumgrd Associte Professor Ntive of southwest Minnesot BS: U of Minnesot MS: U of Minnesot Advisor: Brin Crooker Thesis: Effects of genetic selection for milk yield on somtotropin prmeters
More informationDietary oil composition differentially modulates intestinal endotoxin transport and postprandial endotoxemia
Mni et l. Nutrition & Metolism 2013, 10:6 http://www.nutritionndmetolism.com/content/10/1/6 RESEARCH Open Access Dietry oil composition differentilly modultes intestinl endotoxin trnsport nd postprndil
More informationSUPPLEMENTARY INFORMATION
SUPPLEMENTARY INFORMATION doi:10.1038/nture11225 Numer of OTUs sed on 3% distnce Numer of 16s rrna-sed V2-V4 tg sequences LF MF PUFA Supplementry Figure 1. High-ft diets decrese the richness nd diversity
More informationEFFECTS OF AN ACUTE ENTERIC DISEASE CHALLENGE ON IGF-1 AND IGFBP-3 GENE EXPRESSION IN PORCINE SKELETAL MUSCLE
Swine Dy 22 Contents EFFECTS OF AN ACUTE ENTERIC DISEASE CHALLENGE ON IGF-1 AND IGFBP-3 GENE EXPRESSION IN PORCINE SKELETAL MUSCLE B. J. Johnson, J. P. Kyser, J. D. Dunn, A. T. Wyln, S. S. Dritz 1, J.
More informationRoughage Type & Level & Grain Processing Interactions with Distiller s s Grains Diets. Matt May High Plains Bio Fuels Co-Product Nutrition Conference
Roughge Type & Level & Grin Processing Interctions with Distiller s s Grins Diets Mtt My High Plins Bio Fuels Co-Product Nutrition Conference Why do we flke grin? Stem-flked corn (SFC) vs. dry-rolled rolled
More informationThe effect of dietary α-linolenic acid levels on regulation of omega-3 lipid synthesis in rat
The effect of dietry α-linolenic cid levels on regultion of omeg-3 lipid synthesis in rt Wei-Chun Tu School of Agriculture Food nd Wine The University of Adelide Conversion of PUFA to LCPUFA PUFA LCPUFA
More informationOptimisation of diets for Atlantic cod (Gadus morhua) broodstock: effect of arachidonic acid on egg & larval quality
Optimistion of diets for Atlntic cod (Gdus morhu) roodstock: effect of rchidonic cid on egg & lrvl qulity Dr Gordon Bell, Ms. An Blnco, Dr Bill Roy, Dr Derek Roertson, Dr Jim Henderson nd Mr Richrd Prickett,
More informationMecadox. Improves pig performance in a wide range of health and growing conditions. (Carbadox) Talk With a Phibro Expert:
SWINE (Crbdox) Improves pig performnce in wide rnge of helth nd growing conditions The Advntge Over the yers, medicted feed dditive hs proven to be cost-effective mngement tool for improving pig performnce
More informationThe Ever Changing World of Feed Additives in The Poultry Industry
The Ever Chnging World of Feed Additives in The Poultry Industry B. S. Lumpkins nd G.F. Mthis Southern Poultry Reserch Inc. Athens, GA, USA Outline Southern Poultry Reserch Impct of ethnol production of
More informationFeeding state and age dependent changes in melaninconcentrating hormone expression in the hypothalamus of broiler chickens
Supplementry Mterils Epub: No 2017_23 Vol. 65, 2018 https://doi.org/10.183/bp.2017_23 Regulr pper Feeding stte nd ge dependent chnges in melninconcentrting hormone expression in the hypothlmus of broiler
More informationThe effect of encapsulated butyric acid and zinc on performance, gut integrity and meat quality in male broiler chickens 1
The effect of encpsulted utyric cid nd zinc on performnce, gut integrity nd met qulity in mle roiler chickens 1 Astrct This study evluted the impct of encpsulted utyric cid nd zinc (ButiPEARL Z) on performnce
More informationUSE OF SORGHUM-BASED DISTILLERS GRAINS IN DIETS FOR NURSERY AND FINISHING PIGS
Swine Dy 1996 USE OF SORGHUM-BASED DISTILLERS GRAINS IN DIETS FOR NURSERY AND FINISHING PIGS B. W. Senne, J. D. Hncock, I. Mvromichlis, S. L. Johnston, P. S. Sorrell, I. H. Kim, nd R. H. Hines Summry Two
More informationExcessive fructose intake causes 1,25-(OH) 2 D 3 -dependent inhibition of intestinal and renal calcium transport in growing rats
Am J Physiol Endocrinol Met 3: E33 E33, 3. First pulished April 9, 3; doi:.5/jpendo.58.. Excessive fructose intke cuses,5-(oh) D 3 -dependent inhiition of intestinl nd renl clcium trnsport in growing rts
More informationEffects of physical exercise on working memory and prefrontal cortex function in post-stroke patients
Effects of physicl exercise on working memory nd prefrontl cortex function in post-stroke ptients M Moriy, C Aoki, K Sktni Grdute School of Helth Sciences Reserch, Mjor of Physicl Therpy, TeikyoHeisei
More informationEffect of kazunoko lipid on the concentrations of plasma glucose and lipids and liver lipids in mice
Effect of kzunoko lipid on the concentrtions of plsm glucose nd lipids nd liver lipids in mice Ntionl Food Reserch Institute Tomoyuki Higuchi, Nouy Shiri nd Hirmitsu Suzuki INTRODUCTION Kzunoko, which
More informationBioactive milk components to secure growth and gut development in preterm pigs ESTER ARÉVALO SUREDA PIGUTNET FA1401 STSM
Bioctive milk components to secure growth nd gut development in preterm pigs ESTER ARÉVALO SUREDA PIGUTNET FA1401 STSM STSM Pigutnet FA1401 STSM 03/Septemer 30/Novemer/2017 (3 months) Host: Home: Thoms
More informationEffect of supplemental fat from dried distillers grains with solubles or corn oil on cow performance, IGF-1, GH, and NEFA concentrations 1
Effect of supplementl ft from dried distillers grins with solules or corn oil on cow performnce, IGF-1, GH, nd NEFA concentrtions 1 Aigil Brtosh 2, Cody Wright 3, Aimee Wertz-Lutz 4, nd George Perry 5
More informationDr. Javier Polo Vice President Research & Development
Efecto de l suplementción con concentrdo de inmunoglobulins prtir del suero bovino en l Microbiot y su contribución l slud intestinl y l sistem nervioso centrl Dr. Jvier Polo Vice President Reserch & Development
More informationEFFECTS OF INGREDIENT AND WHOLE DIET IRRADIATION ON NURSERY PIG PERFORMANCE
Swine Dy 21 EFFECTS OF INGREDIENT AND WHOLE DIET IRRADIATION ON NURSERY PIG PERFORMANCE J. M. DeRouchey, M. D. Tokch, J. L. Nelssen, R. D. Goodbnd, S. S. Dritz 1, J. C. Woodworth, M. J. Webster, B. W.
More informationEVALUATION OF DIFFERENT COPPER SOURCES AS A GROWTH PROMOTER IN SWINE FINISHING DIETS 1
Swine Dy 2001 Contents EVALUATION OF DIFFERENT COPPER SOURCES AS A GROWTH PROMOTER IN SWINE FINISHING DIETS 1 C. W. Hstd, S. S. Dritz 2, J. L. Nelssen, M. D. Tokch, nd R. D. Goodbnd Summry Two trils were
More information3/10/ Energy metabolism o How to best supply energy to the pig o How the pig uses energy for growth
Keeping Control of Feed Costs in n Uncertin Mrket Presented To: Iow Pork Producers Assocition Regionl Meetings Februry, 2009 John F. Ptience Iow Stte University Ames, IA Outline Wht s new in swine nutrition
More information2018 American Diabetes Association. Published online at
Supplementry Figure S1. Ft-1 mice exhibit reduced diposity when fed n HFHS diet. WT nd ft-1 mice were fed either control or n HFHS diet for 18 weeks. A: Representtive photogrphs for side-by-side comprison
More informationTHE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS
THE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS THE EVALUATION OF DEHULLED CANOLA MEAL IN THE DIETS OF GROWING AND FINISHING PIGS John F. Ptience nd Doug Gillis SUMMARY
More information* * * * * liver kidney ileum. Supplementary Fig.S1
Supplementry Fig.S1 liver kidney ileum Fig.S1. Orlly delivered Fexrmine is intestinlly-restricted Mice received vehicle or Fexrmine (100mg/kg) vi per os (PO) or intrperitonel (IP) injection for 5 dys (n=3/group).
More informationEffect of processing on in vitro bioaccessibility of phenolics, flavonoids and antioxidant activity of vegetables with/without yoghurt
Effect of processing on in vitro ioccessiility of phenolics, flvonoids nd ntioxidnt ctivity of vegetles with/without yoghurt Assoc. Prof. Dr. Esr ÇAPANOĞLU GÜVEN Deprtment of Food Engineering Istnul Technicl
More informationSows with high milk production had both a high feed intake and high body mobilization
Animl (2017), 11:11, pp 1913 1921 The Animl Consortium 2017 doi:10.1017/s1751731117000155 niml Sows with high milk production hd oth high feed intke nd high ody moiliztion A. V. Strthe 1, T. S. Bruun 2
More informationCheck your understanding 3
1 Wht is the difference etween pssive trnsport nd ctive trnsport? Pssive trnsport is the movement of prticles not requiring energy. Movement of prticles in ctive trnsport uses energy. 2 A gs tp in the
More informationSupporting immune function in a post-antibiotic world. Demand for poultry products
Supporting immune function in post-ntibiotic world Doug Korver University of Albert, Edmonton, AB Cnd Western Poultry Conference 2018 Demnd for poultry products Chicken will surpss pork s the most consumed
More informationJie Luo, 1 Feiruo Huang, 1 Chenglin Xiao, 1 Zhengfeng Fang, 1 Jian Peng, 1 and Siwen Jiang Introduction
BioMed Reserch Interntionl Volume 2013, Article ID 905918, 9 pges http://dx.doi.org/10.1155/2013/905918 Reserch Article Responses of Growth Performnce nd Proinflmmtory Cytokines Expression to Fish Oil
More informationENERGY CONTENT OF BARLEY
ENERGY CONTENT OF BARLEY VARIATION IN THE DIETARY ENERGY CONTENT OF BARLEY Shwn Firbirn, John Ptience, Hnk Clssen nd Ruurd Zijlstr SUMMARY Formultion of commercil pig diets requires n incresing degree
More informationThe Effects of High-Oil Corn or Typical Corn with or without Supplemental Fat on Diet Digestibility in Finishing Steers
Beef Reserch Report, 2000 Animl Science Reserch Reports 2001 The Effects of High-Oil Corn or Typicl Corn with or without Supplementl Ft on Diet Digestibility in Finishing Steers Crig R. Belknp Iow Stte
More informationProducts for weaners Benzoic acid or the combination of lactic acid and formic acid
Products for weners Benzoic cid or the comintion of lctic cid nd formic cid Tril report no.: 490 Novemer, 000 Hnne Mrio, Lrs Egelund Olsen, Bent Borg Jensen 1 nd Nuri Miquel 1 The Ntionl Committee for
More informationEFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS
EFFECT OF DIETARY ENZYME ON PERFORMANCE OF WEANLING PIGS Finl report sumitted to Dniso Animl Nutrition E. vn Heugten nd B. Frederik North Crolin Stte University, Deprtment of Animl Siene Summry The urrent
More informationSoybean Hulls as an Alternative Feed for Horses
Animl Industry Report AS 650 ASL R1931 2004 Soyben Hulls s n Alterntive Feed for Horses Josie Booth Iow Stte University Howrd Tyler Iow Stte University Peggy Miller-Auwerd Iow Stte University Jenette Moore
More informationInheritance of cholesterol metabolism of probands with high or low cholesterol absorption
Inheritnce of cholesterol metolism of pronds with high or low cholesterol sorption Helen Gylling* nd Ttu A. Miettinen 1, Deprtment of Clinicl Nutrition,* University of Kuopio, nd Kuopio University Hospitl,
More informationThe Effects of Diet Particle Size on Animal Performance
MF-2050 Feed Mnufcturing Feed Mnufcturing Cerel grins re the primry energy source in swine nd poultry diets. Therefore, not only must producers be concerned bout the composition of the grin, but lso how
More informationB. Koven 1*, E. Gisbert 2, O. Nixon 1, I. Meiri-Ashkenazi 1, A. Gaon 1, M.M. Solovyev 3,4, A. Tandler 1, H. Rosenfeld 1
DESIGNING WEANING DIETS BASED ON THE ONTOGENY OF DIGESTIVE TRACT ENZYME ACTIVITY DURING THE CARNIVOROUS-OMNIVOROUS TRANSITION IN GREY MULLET (MUGIL CEPHALUS) JUVENILES B. Koven 1*, E. Gisert 2, O. Nixon
More informationPotential of plant-derived antimicrobials for controlling zoonotic and food-borne diseases
Potentil of plnt-derived ntimicrobils for controlling zoonotic nd food-borne diseses Kumr Venkitnrynn, DVM, MVSc, MS, Ph.D. Professor of Microbiology Grdute Progrms Chir Deprtment of Animl Science University
More informationImplication of fermentable carbohydrates targeting the gut microbiota on conjugated linoleic acid production in high-fat-fed mice
British Journl of Nutrition, pge 1 of 14 q The Authors 213 doi:1.117/s7114513123 Impliction of fermentle crohydrtes trgeting the gut microiot on conjugted linoleic cid production in high-ft-fed mice Céline
More informationDegree of SGLT1 phosphorylation is associated with but does not determine segment-specific glucose transport features in the porcine small intestines
ORIGINAL RESEARCH Physiologicl Reports ISSN 2051-817X Degree of SGLT1 phosphoryltion is ssocited with ut does not determine segment-specific glucose trnsport fetures in the porcine smll intestines Stefnie
More informationSESSIONE I: RELATORI. Ghrelin: from oroxigenic signal to metabolic master regulator?
SESSIONE I: RELATORI Ghrelin: from oroxigenic signl to metbolic mster regultor? Prof. Rocco Brzzoni Professore ssocito di Medicin Intern Università degli Studi di Trieste Ghrelin: d segnle oressizznte
More informationEffect of Field Pea Replacement and Yucca schidigera extract on weaning transition growth and feedlot performance
Effect of Field Pe Replcement nd Yucc schidiger extrct on wening trnsition growth nd feedlot performnce D.G. Lndblom 1 nd J. Pennington 2 1 Dickinson Reserch Extension Center, Dickinson, ND 2 Dickinson
More informationSupplementary Online Content
Supplementry Online Content Zulmn DM, Pl Chee C, Ezeji-Okoye SC, et l. Effect of n intensive outptient progrm to ugment primry cre for high-need Veterns Affirs ptients: rndomized clinicl tril. JAMA Intern
More informationVitamin D and Mushrooms: Enrichment With Pulsed UV Light. Michael Kalaras Department of Food Science The Pennsylvania State University
Vitmin D nd Mushrooms: Enrichment With Pulsed UV Light Michel Klrs Deprtment of Food Science The Pennsylvni Stte University Vitmin D Synthesis Source: http://vitmind.ucr.edu/imges/chem1.gif Vitmin D In
More informationREVIEWING NUTRIENT DELIVERY FROM BIRTH TO WEANING. Mike Van Amburgh Department of Animal Science Cornell University, Ithaca, NY TAKE HOME MESSAGES
REVIEWING NUTRIENT DELIVERY FROM BIRTH TO WEANING Mike Vn Amurgh Deprtment of Animl Science Cornell University, Ithc, NY TAKE HOME MESSAGES 1. The pre-wening period is period of life where the clf is undergoing
More informationEffects of Dietary Conjugated Linoleic Acid and Biopolymer Encapsulation on Lipid Metabolism in Mice
Int. J. Mol. Sci. 2013, 14, 6848-6862; doi:10.3390/ijms14046848 Article OPEN ACCESS Interntionl Journl of Moleculr Sciences ISSN 1422-0067 www.mdpi.com/journl/ijms Effects of Dietry Conjugted Linoleic
More informationThe Journal of Physiology
J Physiol 595.13 (2017) pp 4379 4398 4379 Impct of perintl exposure to sucrose or high fructose corn syrup (HFCS-55) on diposity nd heptic lipid composition in rt offspring Crl R. Toop 1, Beverly S. Muhlhusler
More informationA. Kinoshita 1, L. Locher 2, R. Tienken 3, U. Meyer 3, S. Dänicke 3, J. Rehage 4, K. Huber 5
Effects of dietry nicin supplementtion on heptic expression of FoxO nd genes involved in glucose production in diry cows during the trnsition period A. Kinoshit, L. Locher, R. Tienken 3, U. Meyer 3, S.
More informationSUPPLEMENTARY INFORMATION
doi:10.1038/nture09973 Plsm Memrne Phgosome TLR1/2/4 ROS Mitochondrion ROS OXPHOS Complex I ROS TRAF6 NADPH Oxidse Supplementry Figure 1 Model detiling the roles of mitochondril ROS in mcrophge cteril
More informationEffects of Different Sources and Levels of Selenium on Performance, Thyroid Function and Antioxidant Status in Stressed Broiler Chickens
Interntionl Journl of Poultry Science 8 (6): 583-587, 2009 ISSN 1682-8356 Asin Network for Scientific Informtion, 2009 Effects of Different Sources nd Levels of Selenium on Performnce, Thyroid Function
More informationDecreasing Diet Density: Direct Fed Microbials and L-Threonine 1,2
Interntionl Journl of Poultry Science 9 (): -9, 00 ISSN 68-86 Asin Network for Scientific Informtion, 00 Decresing Diet Density: Direct Fed Microils nd L-Threonine, 4 4,4 4 6 M.T. Kidd, A. Corzo, W.A.
More informationScientific research on the biological value of olive oil
Scientific reserch on the biologicl vlue olive oil Cov F.G. Ally M. (ed.). L' économie de l' olivier Pr : CIHEAM Options Méditerrnéennes : Série Etudes; n. 1988-V 1988 pges 149-152 Article vilble on le
More informationEffect of Dietary Selenium on Small Intestine Villus Integrity in Reovirus-Challenged Broilers
Interntionl Journl of Poultry Science 8 (9): 829-835, 2009 ISSN 1682-8356 sin Network for Scientific Informtion, 2009 Effect of Dietry Selenium on Smll Intestine Villus Integrity in Reovirus-Chllenged
More informationDietary influence on organ size and in vitro oxygen consumption by visceral organs of growing pigs
Livestock Prouction Science 65 (2000) 229 237 www.elsevier.com/ locte/ livprosci Dietry influence on orgn size n in vitro oxygen consumption y viscerl orgns of growing pigs C.M. Nychoti, C.F.M. e Lnge
More informationBritish Journal of Nutrition
British Journl of Nutrition (2015), 113, 923 934 doi:10.1017/s0007114514003201 q The Authors 2015. This is n Open Access rticle, distriuted under the terms of the Cretive Commons Attriution licence (http://cretive
More informationHydroxy Minerals - The Newest Development in Mineral Nutrition
Hydroxy Minerls - The Newest Development in Minerl Nutrition By Jeff Cohen nd F. A. Stewrd For t lest 3 yers nutritionl sources of essentil trce minerls such s iron, zinc, copper nd mngnese hve een commonly
More informationShamsuddin M. Mamun, U. Focken, G. Francis and K. Becker University of Hohenheim, Stuttgart, Germany. September 2004
A GROWTH PERFORMANCE AND METABOLIC RATES OF GENETICALLY IMPROVED AND CONVENTIONAL STRAINS OF NILE TILAPIA, OREOCHROMIS NILOTICUS (L.) Shmsuddin M. Mmun, U. Focken, G. Frncis nd K. Becker University of
More informationEffect of Aqueous Extract of Carica papaya Dry Root Powder on Lactation of Albino Rats
Effect of Aqueous Extrct of Cric ppy Dry Root Powder on Lcttion of Alino Rts G. Tosswnchuntr nd S. Aritjt Deprtment of Biology Fculty of Science Ching Mi University Ching Mi 50200 Thilnd Keywords: mmmry
More informationEffect of Different Dietary Energy Sources on Induction of Fatty Liver-Hemorrhagic Syndrome in Laying Hens
Interntionl Journl of Poultry Science 7 (12): 1232-1236, 2008 ISSN 1682-8356 sin Network for Scientific Informtion, 2008 Effect of Different Dietry Energy Sources on Induction of Ftty Liver-Hemorrhgic
More informationHow adaptations of substrate utilization regulate body composition
(27) 1 6 & 27 Nture Pulishing Group All rights reserved 37-565/7 $3. www.nture.com/ijo ORIGINAL ARTICLE How dpttions of sustrte utiliztion regulte ody composition KD Hll, HL Bin nd CC Chow Lortory of Biologicl
More informationBritish Journal of Nutrition
(2015), 113, 610 617 q The Authors 2015 doi:10.1017/s0007114514004231 Down-regultion of monocrboxylte trnsporter 1 (MCT1) gene expression in the colon of piglets is linked to bcteril protein fermenttion
More informationINFLUENCE OF DIFFERENT STRAINS AND WAYS OF INOCULATION ON THE RABBIT S RESPONSE TO EXPERIMENTAL INFECTION WITH PASTEURELLA MULTOCIDA
Pthology nd Hygiene INFLUENCE OF DIFFERENT STRAINS AND WAYS OF INOCULATION ON THE RABBIT S RESPONSE TO EXPERIMENTAL INFECTION WITH PASTEURELLA MULTOCIDA Kulcsár G. 1, Fáián K. 1 *, Brn T. 1, Virág Gy.
More informationChromium Content Of Feedstuffs. Chromium An Essential Nutrient. Which Tissue?
CHROMIUM FOR DAIRY CATTLE Chromium Content Of Feedstuffs Feedstuff Avil Cr in Diry Production A. Geiger, Ph.D. Zinpro Corportion Psture 0.8 Whet silge 2.2 Dehydrted lflf 0.2 Corn silge 2.0 Ryegrss 0.4
More informationdoi: /s British Journal of Nutrition (2016), 115, The Authors 2016
British Journl of Nutrition (2016), 115, 2236 2245 The Authors 2016 doi:10.1017/s0007114516000842 Supplementtion of rnched-chin mino cids to reduced-protein diet improves growth performnce in piglets:
More informationA FACTORIAL STUDY ON THE EFFECTS OF β CYCLODEXTRIN AND POLOXAMER 407 ON THE SOLUBILITY AND DISSOLUTION RATE OF PIROXICAM
IJRPC 20, (3) Chowdry et l. ISSN: 223 278 INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACY AND CHEMISTRY Aville online t www.ijrpc.com Reserch Article A FACTORIAL STUDY ON THE EFFECTS OF β CYCLODEXTRIN AND
More informationBackground Pears (Pyrus L.) are one of the leading cultivated fruit trees in China following apples and oranges in planting area and fruit yield.
Nnjing Agriculturl University Potssium enhnces the sugr ssimiltion in leves nd fruit y regulting the expression of key genes involved in sugr metolism of Asin pers Cixi Dong, Chngwei Shen, Yngchun Xu College
More informationMeseret Girma, Berhan Tamir and Tadelle Dessie 1. Department of Animal Sciences, Wollo University, P.O. Box 1145, Dessie, Ethiopia 2
Interntionl Journl of Poultry Science 11 (1): 65-72, 2012 ISSN 1682-8356 Asin Network for Scientific Informtion, 2012 Effects of Replcing Penut Seed Cke with Brewery Dried Yest on Lying Performnce, Egg
More information*** *** *** *** T-cells T-ALL. T-cells T-ALL. T-cells T-ALL. T-cells T-ALL. T-cells T-ALL. Relative ATP content. Relative ATP content RLU RLU
RLU Events 1 1 1 Luciferin (μm) T-cells T-ALL 1 1 Time (min) T-cells T-ALL 1 1 1 1 DCF-DA Reltive ATP content....1.1.. T-cells T-ALL RLU 1 1 T-cells T-ALL Luciferin (μm) 1 1 Time (min) c d Control e DCFH-DA
More informationExtraction and Some Functional Properties of Protein Extract from Rice Bran
Ksetsrt J. (Nt. Sci.) 40 : 209-214 (2006) Extrction nd Some Functionl Properties of Protein Extrct from Rice Brn Chockchi Theerkulkit*, Siree Chiseri nd Siriwt Mongkolknchnsiri ABSTRACT Rice brn protein
More informationSurface Area of the Tip of the Enterocytes in Small Intestine Mucosa of Broilers Submitted to Early Feed Restriction and Supplemented with Glutamine
Interntionl Journl of Poultry Science 6 (1): 31-35, 007 ISSN 168-8356 Asin Network for Scientific Informtion, 007 Surfce Are of the Tip of the Enterocytes in Smll Intestine Mucos of Broilers Sumitted to
More informationEffects of Recombinant Bovine Somatotropin Administration at Breeding on the Cow, Conceptus and Subsequent Offspring Performance of Beef Cattle
Effects of Recominnt Bovine Somtotropin Administrtion t Breeding on the Cow, Conceptus nd Susequent Offspring Performnce of Beef Cttle V. R. G. Mercdnte 1, F. M. Cirico 1, D. D. Henry 1, P. L. P. Fontes
More informationImmunobiotic Lactobacillus jensenii as immune-health promoting factor to improve growth performance and productivity in post-weaning pigs
Sud et l. BMC Immunology 2014, 15:24 RESEARCH ARTICLE Open Access Immunobiotic Lctobcillus jensenii s immune-helth promoting fctor to improve growth performnce nd productivity in post-wening pigs Yoshihito
More informationChoice Feeding of Two Different Broiler Strains Using Diets with Constant Energy Level 1
Interntionl Journl of Poultry Science 7 (8): 726-737, 2008 ISSN 1682-8356 Asin Network for Scientific Informtion, 2008 Choice Feeding of Two Different Broiler Strins Using Diets with Constnt Energy Level
More informationBritish Journal of Nutrition
British Journl of Nutrition (215), 113, 1862 1875 q The Authors 215 doi:1.117/s7114515121x Anormlities in myo-inositol metolism ssocited with type 2 dietes in mice fed high-ft diet: enefits of dietry myo-inositol
More informationEvidence for facilitated lactate uptake in lizard skeletal muscle
The Journl of Experimentl Biology 24, 499 46 (2) Printed in Gret Britin The Compny of Biologists Limited 2 JEB3537 499 Evidence for fcilitted lctte uptke in lizrd skeletl muscle E. R. Donovn* nd T. T.
More informationNorthern blot analysis
Northern blot nlysis RNA SCD RNA SCD FAS C c-9 t-1 C c-9 t-1 PRE PI PDMI PRE PI PDMI PRE PDMI PIM An W c-9, t-11 t-1, c-12 C 5 2 4 1 um C 5 2 4 1 um Angus dipocytes expressed SCD higher thn Wgyu dipocyte
More informationEffects of Dietary Protein and Energy on Growth Performance and Carcass Characteristics of Betong Chickens (Gallus domesticus) During Growing Period
Interntionl Journl of Poultry Science 9 (5): 468-472, 2010 ISSN 1682-8356 Asin Network for Scientific Informtion, 2010 Effects of Dietry Protein nd Energy on Growth Performnce nd Crcss Chrcteristics of
More informationInflammation & Cell Signaling 2014; 1: e117. doi: /ics.117; 2014 by Nirmal Verma, et al.
Inflmmtion & Cell Signling 14; 1: e117. doi: 1.148/ics.117; 14 y Nirml Verm, et l. http://www.smrtscitech.com/index.php/ics RESEARCH HIGHLIGHT Siliinin meliortes Dextrn Sodium Slt induced colitis in mice
More informationSandra Grbić Vladimir Lukić Ivan Kovačević Jelena Parojčić Zorica Đurić
Deprtment of Phrmceuticl Technology nd Cosmetology Fculty of Phrmcy University of Belgrde An investigtion into the possibilities nd limittions of in silico bsorption modeling: GstroPlus TM simultion of
More informationGeographical influence on digit ratio (2D:4D): a case study of Andoni and Ikwerre ethnic groups in Niger delta, Nigeria.
Journl of Applied Biosciences 27: 1736-1741 ISSN 1997 5902 Geogrphicl influence on digit rtio (2D:4D): cse study of Andoni nd Ikwerre ethnic groups in Niger delt, Nigeri. Gwunirem, Isrel U 1 nd Ihemelndu,
More informationChoose right carbohydrates and right fats (RCRF) - keys to optimal health
Editoril on Nutrition Choose right crbohydrtes nd right fts (RCRF) - keys to optiml helth Stig Bengmrk Division of Surgery & Interventionl Science, University College London, London, UK Correspondence
More informationEgg quality, fatty acid composition and immunoglobulin Y content in eggs from laying hens fed full fat camelina or flax seed
Cherin nd Quezd Journl of Animl Science nd Biotechnology (2016) 7:15 DOI 10.1186/s40104-016-0075-y RESEARCH Open Access Egg qulity, ftty cid composition nd immunogloulin Y content in eggs from lying hens
More informationInflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)
Pooley et l. BMC Genomics 213, 14:747 http://www.iomedcentrl.com/1471-2164/14/747 ESEACH ATICLE Open Access Inflmmtory responses in primry muscle cell cultures in Atlntic slmon (Slmo slr) Nichols J Pooley
More informationCyanidin-3-O-glucoside ameliorates lipid and glucose accumulation in C57BL/6J mice via activation of PPAR-α and AMPK
3 rd Interntionl Conference nd Exhiition on Nutrition & Food Sciences Septemer 23-25, 214 Vlenci, Spin Cynidin-3-O-glucoside meliortes lipid nd glucose ccumultion in C57BL/6J mice vi ctivtion of PPAR-α
More informationAdipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm
Adipocyte in vsculr wll cn induce the rupture of dominl ortic neurysm Hiron Kugo 1 *, Nouhiro Zim 1 *, Hiroki Tnk 2 *, Youhei Mouri 1, Kenichi Yngimoto 3, Kohsuke Hymizu 3,4, Keisuke Hshimoto 1, Tkeshi
More informationDo pigs benefit from omega-3 fatty acids?
Do pigs benefit from omega-3 fatty acids? Denise Beaulieu Assistant Professor Animal & Poultry Science Introduction What are omega-3 fatty acids? Outline Why would we consider augmenting the diet of growing
More informationOffspring subcutaneous adipose markers are sensitive to the timing of maternal gestational weight gain
Gilin et l. Reproductive Biology nd Endocrinology (2015) 13:16 DOI 10.1186/s12958-015-0009-0 RESEARCH Open Access Offspring sucutneous dipose mrkers re sensitive to the timing of mternl gesttionl weight
More informationSUPPLEMENTARY INFORMATION
. Norml Physiologicl Conditions. SIRT1 Loss-of-Function S1. Model for the role of SIRT1 in the regultion of memory nd plsticity. () Our findings suggest tht SIRT1 normlly functions in coopertion with YY1,
More informationUnlocking Solutions to Chronic Inflammation
to Chronic Inflmmtion Why Feeding Zinpro Performnce Minerls is Key For Success When Formulting Diets for Livestock, Poultry, Aquculture, Equine nd Compnion Animls By Adm Geiger, Ph.D., diry reserch nutritionist,
More informationUse of δ-aminolevulinic Acid in Swine Diet: Effect on Growth Performance, Behavioral Characteristics and Hematological/Immune Status in Nursery Pigs*
97 Use of δ-aminolevulinic Acid in Swine Diet: Effect on Growth Performnce, Behviorl Chrcteristics nd Hemtologicl/Immune Sttus in Nursery Pigs* R. D. Mteo 1, J. L. Morrow 2, J. W. Diley 2, F. Ji 1 nd S.
More informationComparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages
Murk et l. Respirtory Reserch (2018) 19:126 https://doi.org/10.1186/s12931-018-0825-9 RESEARCH Comprison of pro- nd nti-inflmmtory responses in pired humn primry irwy epithelil cells nd lveolr mcrophges
More informationNutrition Guide. National Swine. Protein and Amino Acid Sources for Swine Diets. Introduction. Objectives. Amino Acid Sources
Ntionl Swine Nutrition Guide Protein nd Amino Acid Sources for Swine Diets Introduction Authors Mrci C. Shnnon, University of Missouri Gry L. Allee, University of Missouri Reviewers R. Den Boyd, The Hnor
More informationEffect of linear and random non-linear programming on environmental pollution caused by broiler production
Journl of Novel Applied Sciences Aville online t www.jnsci.org 24 JNAS Journl-24-3-/43-434 ISSN 2322-549 24 JNAS Effect of liner nd rndom non-liner progrmming on environmentl pollution cused y roiler production
More informationGoal: Evaluate plant health effects while suppressing dollar spot and brown patch
Newer Fungicide Products Alone nd In Rottion on Chicgo Golf Green Reserchers: Chicgo District Golf Assoc. Derek Settle, Tim Sibicky, nd Nick DeVries Gol: Evlute plnt helth effects while suppressing dollr
More informationDietary Inclusion of Chicory (Cichorium intybus L.) Affects Pig Intestinal Microenvironment
AEM Accepts, published online hed of print on 6 April 2012 Appl. Environ. Microbiol. doi:10.1128/aem.07702-11 Copyright 2012, Americn Society for Microbiology. All Rights Reserved. Gut bcteril phylotypes
More informationDR. MARC PAGÈS Project Manager R&D Biologicals - Coccidia Projects, HIPRA
DR. MARC PAGÈS Project Mnger R&D Biologicls - Coccidi Projects, HIPRA Dr. Mrc Pgès Bosch otined Microiology nd Genetics degree t the University of Brcelon in 1998. He otined his PhD working on the synptoneml
More informationOverview Background production, fermentable
Microes sustinle qufeed resource for the future Liv Torunn Mydlnd, Odd Helge Romrheim, Thor Lndsverk, Anders Skrede nd Mrgreth Øverlnd. Overview Bckground production, fermentle sustrtes, cell growth type
More informationEffect of 1-Methylcyclopropene on the Physiology and Yield of Cotton. Derrick Oosterhuis Eduardo Kawakami and Dimitra Loka University of Arkansas
Effect of 1-Methylcyclopropene on the Physiology nd Yield of Cotton Derrick Oosterhuis Edurdo Kwkmi nd Dimitr Lok University of Arknss Cotton Crop Gossypium hirsutum Unique out cotton Perennil grown s
More information