Slide 74: Pituitary (Masson s trichrome)

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1 histo074 Slide 74: Pituitary (Masson s trichrome) Infundibular stalk Pars tuberlaris Carcinoma Pars nervosa Pars intermedia Pars distalis

2 Pars distalis Pars intermedia Pars nervosa Pars Pars intermedia Pars distalis Pars 79 nervosa 3 divisions of the pituitary gland: 1. Pars distalis distalis Pars intermedia 2. Pars intermedia 3. Pars nervosa

3 Releasing hormones are distributed in second capillary bed of venous portal system Into the first capillary network Second capillary network

4 Slide # 79 (GT ). Pituitary gland, sheep pars intermedia pituicytes pars distalis pars nervosa basophils acidophils

5 DEMO SLIDE BOXES Pituitary gland, various species. 66a basophils acidophils pars nervosa pars distalis. pars intermedia chromophobes a large colloid-filled cleft (remnant of Rathke s pouch)

6 DEMO SLIDE BOXES Pituitary gland, various species. 66b pars intermedia, pars nervosa pars distalis chromophobes acidophils, basophils,

7 DEMO SLIDE BOXES Pituitary gland, various species. 67a pars intermedia, pars distalis pars nervosa Pituicytes of pars nervosa acidophils, capillary basophils,

8 DEMO SLIDE BOXES Pituitary gland, various species. 67b pars intermedia, pars distalis pars nervosa Pars tuberlaris

9 DEMO SLIDE BOXES Pituitary gland, various species. 68a pars distalis pars distalis pars nervosa pars intermedia, pars nervosa

10 DEMO SLIDE BOXES Pituitary gland, various species. 68b bovine pars intermedia, pars nervosa pars distalis

11 SLIDE # 8 (SH PIT 3A). Pituitary Gland, sheep acidophils (red/orange), basophils (dark pink/purple), and chromophobes (nuclei surrounded by clear cytoplasm) pars distalis pars intermedia, pars nervosa

12 SLIDE # 64 (SH PIT 6A). Pituitary Gland, sheep many veins and nerves acidophils pars imtermedia pars nervosa pars distalis pituicytes

13 490 histo074 Infundibular stalk pars distalis pars distalis

14 490 Herring bodies in pars nervosa of Hypophysis Pars nervosa

15 Slide #80 (Pfi-122a). Thyroid, monkey. colloid represents the storage form of thyroid hormones. thyroglobulin numerous thyroid follicles simple cuboidal parafollicular epithelium termed or C cells, follicular cells produce the hormone calcitonin

16 Slide #80 COLLAGENOUS CONNECTIVE TISSUE (CCT) UNILOCULAR ADIPOSE TISSUE (WHITE FAT) Slide #80 (Pfi-122a). Thyroid, monkey. thyroid follicles calcitonin causes a DECREASE in blood calcium concentrations and the principle counter balance to calcitonin in its regulation of blood calcium levels is PARATHYROID HORMONE

17 Slide #85 (B002-F-159,160). Thyroid gland, cow. thymus thyroid follicles simple cuboidal epithelium follicular cells

18 Slide #53 (PF1-122c). Thyroid gland and lymph node, pig. UNILOCULAR ADIPOSE TISSUE (WHITE FAT) lymph node COLLAGENOUS CONNECTIVE TISSUE (CCT) Thyroid gland thyroid follicles

19 DEMO SLIDE BOX Demo slides # 65a and 65b. Thyroid and parathyroid glands, dog. vascularity of this organ numerous colloid-filled follicles of the thyroid gland principal or chief cells (oxyphil cells) parathyroid glands

20 188 Parathyroid chief cells and oxyphils

21 484 Parathyroid chief cells and oxyphils Osteoporosis due to hyperparathyroidism

22 DEMO SLIDE BOX 135b Demo slide # 135b (EQ-1-1). Adrenal gland, horse. zona glomerulosa outer cortex zona fasciculata zona reticularis inner medulla Blood vessels medulla has chromaffin cells

23 ut186 ZONA GLOMERULOSA ZONA FASCICULATA ZONA RETICULARIS

24 Slide #82 (C007-H-2). Adrenal gland, dog. Note: A special stain was used on this slide. zona glomerulosa zona fasciculata zona reticularis Chromaffin cells the chromaffin reaction. The enteroendocrine cells within the gastrointestinal tract will show the same chromaffin reaction if processed with dichromate.

25 Slide #77 (C007-H-107A). Pancreas, dog. Rich vasculature pancreatic islets PANCREAS HAS CENTROACINAR CELLS But no STRIATED DUCTS

26 Slide #93 (1017). Pancreas, cat. SMALL INTESINE pancreatic islets

27 34218 Rat pancreas Islet cells

28 Pancreas, dog Immunocytochemistry of Islet cells stained for glucagon

29 Pancreas, dog Immunocytochemistry of Islet cells stained for insulin Bata cells producing insulin

30 Pancreas, dog Immunocytochemistry of Islet cells stained for somatostatin

31 Modified from the McGraw-Hill Companies Capillary bed por tal1 ˈpôrdl/ noun 1. Portal vessel Extra parts of a portal system a doorway, gate, or other entrance, especially a large and elaborate one. synonyms: doorway, gateway, entrance, exit, opening

32 (1 st CAPILLARY in hypothalamus) 490 PORTAL VEIN In stalk 490 Human pituitary 2 nd CAPILLARY Pars distalis Pars distalis VENOUS PORTAL SYSTEM

33 Region A Modified from the McGraw-Hill Companies Region B local change in releasing hormones blood composition (first capillary network in region A modifies the blood by adding releasing hormones) and second capillary network in region B (uses hormone rich blood from the portal vessel to alter function of the cells in the pars distalis to produce their specific hormones[ LH, TSH, ACTH])

34 ISLETS Of LANGERHANS First capillary network of the ARTERIAL PORTAL SYSTEM modifies blood composition with insulin / glucagon First capillary network Second capillary network Second capillary network uses the modified blood composition with insulin (+) / glucagon (-) to regulate acinar cell protein enzyme production

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