Second German-Japanese Neuroimmunology Symposium

Transcription

1 Second German-Japanese Neuroimmunology Symposium Eibsee, Thu 9th Sun 12th July 2009 Overview Thursday, July Reception, Welcome Dinner Welcome by Hartmut Wekerle Opening Lecture: Takashi Yamamura Friday, July Session 1: Regulatory cells and basic neuroimmunology Session 2: Migration and models of CNS inflammation Lunch Excursion to Neuschwanstein and Wieskirche (UNESCO world heritage). Dinner in Oberammergau. Saturday, July Session 3: Cytokines and neuroinflammation Session 4: Neurobiology and pathology of MS Lunch Session 5: Therapy Excursion to the Zugspitze with Dinner (Bayerischer Abend) Sunday, July Session 6: Autoreactivity in MS Session 7: NMO and others Lunch and Farewell 2

2 Detailed program THURSDAY Opening remarks: Hartmut Wekerle Opening lecture: Takashi Yamamura FRIDAY Session 1: Regulatory cells and basic neuroimmunology Chairs: Sachiko Miyake and Roland Martin Sachiko Miyake National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo NKT cells and MAIT cells in autoimmune disease Heinz Wiendl Julius Maximilians University of Würzburg Regulatory T cells in MS Atsushi Kumanogoh Research Institute for Microbial Diseases, Osaka University Involvement of semaphorins, axonal guidance cues, in the pathogenesis of EAE via regulating immune cell migration Saburo Sakoda Osaka University Graduate School of Medicine The role of sema4a in multiple sclerosis Coffee break 3

3 Session 2: Migration and models of CNS inflammation Chairs: Avi Ben Nun and Takashi Kanda Takashi Kanda Yamaguchi University Graduate School of Medicine, Ube A new model for studying blood-nerve barrier Britta Engelhardt Theodor Kocher Institute, University of Bern α4-integrins mediate the recruitment of immature dendritic cells across the blood-brain barrier during experimental autoimmune encephalomyelitis Klaus-Armin Nave Max Planck Institute for Experimental Medicine, Göttingen The role of oligodendrocytes in maintaining white matter integrity Guru Krishnamoorthy Max Planck Institute of Neurobiology, Martinsried Spontaneous EAE models Naoto Kawakami Max Planck Institute of Neurobiology, Martinsried Migration patterns of autoreactive T cells Lunch buffet Excursion to Neuschwanstein and Wieskirche Dinner in Oberammergau 4

4 SATURDAY Session 3. Cytokines and neuroinflammation Chairs: Dieter Jenne and Akio Suzumura Burkhard Becher Department of Neurology, University Hospital, Zurich Th17 derived factors: the target organ matters Thomas Korn Technical University Munich Th17 cells and EAE Akio Suzumura Institute of Environmental Medicine, Nagoya University, Nagoya Production and functions of IL-25 in the CNS Martin Kerschensteiner Institute of Clinical Neuroimmunology, Ludwig Maximilians University Munich In vivo pathogenesis of immune-mediated axon damage Norbert Goebels Department of Neurology, University Hospital Zurich Collateral bystander damage by myelin-directed CD8+ T cells causes axonal loss Coffee break Session 4: Neurobiology and Pathology of MS Chairs: Hans-Karl Müller-Hermelink and Takeshi Tabira Christine Stadelmann-Nessler 5

5 Georg August University Göttingen Grey matter damage in inflammatory demyelination Zsolt Illes University of Pecs, Hungary Poly(ADP-ribose) polymerase (PARP) is activated in multiple sclerosis pattern III lesions and its inhibition prevents experimental demyelination and oligodendrocyte death Jun-ichi Satoh Department of Bioinformatics and Molecular Neuropathology, Meiji Pharmaceutical University, Tokyo Molecular network of the comprehensive multiple sclerosis brain lesion proteome Robert Weissert Division of Neurology, Geneva University Hospital Antigen presentation in the CNS in multiple sclerosis Toshimasa Aranami National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo a-b crystalline as an immunomodulator in MS Lunch Session 5: Therapy Chairs: Ludwig Kappos and Jun-ichi Kira Takeshi Tabira National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Tokyo 6

6 Alzheimer s disease vaccine Yoh Matsumoto Tokyo Metropolitan Institute for Neuroscience Non-viral DNA vaccine therapy against Alzheimer's disease-effects, safety and mechanisms of Abeta clearance" Hans-Peter Hartung Heinrich Heine University Düsseldorf Monoclonal antibodies as novel treatment tools for neuroimmunological disorders Ralph Gold Ruhr University Bochum Complications and monitoring of natalizumab therapy Coffee break Continuation of session 5 (Therapy) Ludwig Kappos University Hospital Basel Oral treatments of MS Matthias Meergans Novartis An update on fingolimod Shinji Oki National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo Nuclear receptors as therapeutic target for multiple sclerosis 7

7 16.30 Excursion to the Zugspitze SUNDAY Session 6. Autoreactivity in MS Chairs: Toshimasa Aranami and Alexander Flügel Roland Martin Institute for Neuroimmunology and Clinical Multiple Sclerosis Research, Hamburg CD4+ T cells in MS - Antigen recognition, phenotype and therapeutic implications Klaus Dornmair Max Planck Institute of Neurobiology, Martinsried Reconstitution of functional autoaggressive T cells from biopsy samples Bernhard Hemmer Technical University Munich Antibodies and biomarkers Edgar Meinl Max Planck Institute of Neurobiology, Martinsried Novel axoglial autoantigens Coffee break Session 7: NMO and others Chairs: Susumu Kusunoki and Arthur Melms Susumu Kusunoki Kinki University School of Medicine, Osaka 8

8 Gangliosides and ganglioside complexes as targets for neuroimmunological diseases Jun-ichi Kira Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka AQP4 autoimmune syndrome and anti-aqp4 antibody-negative opticospinal MS in Japanese: neuroimmunological and genetical studies Kazuo Fujihara Tohoku University Graduate School of Medicine, Sendai Neuromyelitis Optica: An Update Monika Bradl Institute for Brain Research, Vienna Testing the pathogenicity of NMO IgG in vivo Fujio Umehara Graduate School of Kagoshima University Recent progress of HTLV-I associated neurological disorders Lunch and Farewell 9