Block DRAFT 17 (Revised )

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1 Block DRAFT 17 (Revised ) April 1, 2019 May 24, Weeks 35 Class days morning hours afternoon hours = total hours 5 Quiz days (33 max total questions per quiz; 50 min max each) 2 Exam days (150 max total questions per exam; 4 hours each) 3 Shelf Exams: Phys and CBS not for grade but required Micro with Immuno required for grade FINAL GRADE ASSIGNED AT END OF BLOCK hours Micro (45 hours lectures + 13 hours labs +1.5 hours conf + 3 h self-study) 18 hours Genetics 5 hours Biostats/Epidemiol 10 hours Doc 1 NEW COMBINED COURSE - Foundations of Disease and Therapeutics - FDT 20hours FDT-Pharm + 1 Sim Labs (0.75 hours) = h 38 hours FDT-Path GRADES TO BLOCK 4 FOR FINAL GRADE 12 hours Ethics In Pathology, 24 students will complete the required Autopsy Experience which is part of their Block 4 Pathology grade. These hours (4.5) are accounted for in the Block 4 hours tally.

2 Block Week 1 1-Apr 2-Apr 3-Apr 4-Apr 5-Apr -8:50 2S04 FDT-PHARM 1 Intro -8:50 2S04 FDT-PHARM 2 General Principles -8:50 2S04 FDT-PHARM 3 Pharmacokinetics 1-8:50 2S04 FDT-PHARM 4 Pharmacokinetics 2-8:50 TC QUIZ 1-9:50 2S04 77 Intro; Lab Safety -10:50 2S04 FDT- 1 Cell Injury/Death 1 Normal Cells/Tissues -11:50 2S04 FDT- 2 Cell Injury/Death 2 Cell Injury -9:50 2S04 78 Ultrastructure 1-10:50 2S04 FDT- 3 Cell Injury/Death 3 Necrosis/Apoptosis -11:50 2S04 79 Ultrastructure 2-9:50 2S04 80 Ultrastructure 3-10:50 2S04 FDT- 4 Cell Injury/Death 4 Cell Aging/Senescence Adaptation to Stress -11:50 2S04 81 Ultrastructure 4-9:50 2S04 82 Genetic Mechanisms: Transformation, Transduction -10:50 2S04 FDT- 5 Cell Injury/Death 5 Clinical Evaluation Cellular Accumulations -11:50 2S04 83 Genetic Mechanisms: Plasmids, Transposons, Conjugation -9:50 2S04 FDT-PHARM 5 Pharmacokinetics 3-10:50 2S04 FDT- 6 Inflammation and Repair 1 Overview -11:50 2S04, 5ELabs LAB Lab 2 Results -3:15 TC NBME Physiology Subject Exam -2:20 8 Rooms ETHICS 1-3:20 2S04 Doc 1 Lecture Sexual History -5:00 Doc 1 Standardized Patients 2N72A, 2E69, 2S11, 2S13, 2S14, 2L48-2:20 2S04, 5ELabs LAB Lab 2 Techniques

3 Block Week 2 8-Apr 9-Apr 10-Apr 11-Apr 12-Apr -8:50 2S04 FDT-PHARM 6 Pharmacodynamics 1 Drug Selectivity -8:50 2S04 FDT-PHARM 7 Pharmacodynamics 2 Drug Receptor Interactions -8:50 2S04 FDT-PHARM 8 Pharmacodynamics 3 Dose-Response Relationship -8:50 2S04 FDT-PHARM 9 Anti-Inflammatory Drugs * NEW in Block 3* -8:50 TC QUIZ 2-9:50 2S04 84 Antibiotic Resistance -9:50 2S04 85 Human Microflora -9:50 2S04 87 Staphylococcus -9:50 2S04 89 Streptococci 2-9:50 2S04 FDT-PHARM 10 Anti-Inflammatory Drugs Autocoids -10:50 2S04 FDT- 7 Inflammation and Repair 2 Leucocyte Recruitment and related -11:50 2S04 FDT- 8 Inflammation and Repair 3 Chronic Inflammation -10:50 2S04 FDT- 9 Inflammation and Repair 4 Inflammatory Mediators Local-Derived -11:50 2S04 86 Bacterial Pathogenic Mechanisms -10:50 2S04 FDT- 10 Inflammation and Repair 5 Inflammatory Mediators Liver-Derived -11:50 2S04 88 Streptococci 1-10:50 2S04 FDT- 11 Inflammation and Repair 6 Repair/Regeneration/Scar -11:50 2S04 90 Neisseria and related -10:50 2S04 FDT- 12 Inflammation and Repair 7 Organ System Inflammation/Systemic Effects/Acute Phase -11:50 2S04 91 Haemophilus and related - AUTOPSY EXPERIENCE (Group :20 2S04, 5ELabs Lab 3 Techniques -2:20 8 Rooms ETHICS 2

4 Block Week 3 15-Apr 16-Apr 17-Apr 18-Apr 19-Apr -8:50 2S04 FDT- 13 Immune System & Disease 1-8:50 2S04 FDT- 16 Immune System & Disease 4-8:50 2S04 FDT- 19 Immune System & Disease 6-8:50 TC QUIZ 3-9:50 2S04 92 Bordetella -9:50 2S04 93 Pseudomonas and related -9:50 2S04 94 Campylobacter, Helicobacter, and related -9:50 2S04 FDT-PHARM 11 Immune Modulators * NEW in Block 3* -10:50 2S04 FDT- 14 Immune System & Disease 2-11:50 2S04 FDT- 15 Immune System & Disease 3-10:50 2S04 FDT- 17 Immune System & Disease 5-11:50 2S04 FDT- 18 Lab 1-10:50 2S04 FDT- 20 Hemodynamics/Shock 1 Edema, Effusion, Transudate vs. Exudate; Hyperemia, Congestion, Hemorrhage -11:50 2S04 95 Enterobacteraceae 1-10:50 2S04 FDT- 21 Hemodynamics/Shock 2 Hemostasis, Embolism, Infarct -11:50 2S04, 7ELabs FDT- 22 Hemodynamics/Shock 3 Shock & Heart Failure - AUTOPSY EXPERIENCE (Group :20 2S04, 5ELabs Lab 4 Staph/Strep - Autopsy Slide Review (Group :20 8 Rooms ETHICS 3 STATE HOLIDAY

5 Block Week 4 22-Apr 23-Apr 24-Apr 25-Apr 26-Apr -8:50 2S04 FDT-PHARM 12 Overview -8:50 2S04 FDT-PHARM 13 Cholinergic Receptor Targets -8:50 2S04 FDT-PHARM 15 Cholinergic Receptor Targets -8:50 2S04 FDT-PHARM 17 Adrenergic Receptor Targets -8:50 2S Listeria; Gardnerella -9:50 2S04 96 Enterobacteraceae 2-9:50 2S04 98 Treponemes; Borrelia -9:50 2S04 99 Leptospira; Zoonoses 1-9:50 2S Zoonoses 2; Corynebacteria -9:50 2S Chlamydia, Chlamydophila -10:50 2S04 GEN 1-10:50 2S04 GEN 2-10:50 2S04 GEN 3-10:50 2S04 GEN 4-10:50 2S04 FDT- 23 Neoplasia 1 Intro/Basic Nomenclature -11:50 2S04 97 Enterobacteraceae 3; Vibrio -11:50 2S04 FDT-PHARM 14 Cholinergic Receptor Targets -11:50 2S04 FDT-PHARM 16 Adrenergic Receptor Targets -11:50 2S04 FDT-PHARM 18 Adrenergic Receptor Targets Available for Optional Voluntary Review Sessions - AUTOPSY EXPERIENCE (Group :20 2S04, 5ELabs Lab 5 Gram Negs - Autopsy Slide Review (Group :20 8 Rooms ETHICS 4-3:20 2S04 Doc 1 Lecture Grief & Depression -5:00 Doc 1 Standardized Patients 2N72A, 2E69, 2S11, 2S13, 2S14, 2L48-1:45 1:45- FDT-PHARM 19A Human Sim B (2 shifts) -3:15 3:15- FDT-PHARM 19B Human Sim B (2 shifts)

6 Block Week 5 29-Apr 30-Apr 1-May 2-May 3-May -Noon EXAM 1 TC -8:50 2S04 GEN 5-9:50 2S Rickettsia and related -8:50 2S04 GEN 6-9:50 2S Mycobacteria 1-8:50 2S04 GEN 7-9:50 2S04 GEN 8 GRADUATION DAY - AM BSOM Commencement East Campus Student Center -10:50 2S Mycoplasma, Legionella -11:50 2S04 FDT- 24 Neoplasia 2 Dysplasia/Neoplasms/ Metastasis -10:50 2S Mycobacteria 2, Nocardia, Actinomyces, misc. -11:50 2S04 FDT- 25 Neoplasia 3 Cancer Molecular Basis and Epidemiology Noon-12:50 TC Block 3 Exam 1 Secure Exam Review -10:50 2S Bacillus -11:50 2S04 FDT- 26 Neoplasia 4 Cancer Etiology/Host Defense - AUTOPSY EXPERIENCE (Group Autopsy Slide Review (Group :20 8 Rooms ETHICS 5-3:20 2S04 Doc 1 Lecture Giving Bad News -5:00 Doc 1 Standardized Patients 2N72A, 2E69, 2S11, 2S13, 2S14, 2L48-2:20 2S04, 5ELabs Lab 6 STD/UTI -5:00 Brody Aud Awards Ceremony - 2N72A M1 Fireside Chat (Optional) 7:00- PM ECU Main Commencement Dowdy-Ficklen Stadium

7 Block Week 6 6-May 7-May 8-May 9-May 10-May -8:50 2S04 GEN 9-9:50 2S Clostridia -8:50 2S04 GEN 10-9:50 2S Non-sporeforming anaerobes -8:50 2S04 GEN 11-9:50 2S04 FDT- 30 Neoplasia 8 Oncogenes -8:50 2S04 GEN 12-9:50 2S Mycology 2 Subcutaneous Mycoses -8:50 TC QUIZ 4-9:50 2S Mycology 3 Systemic Mycoses -10:50 2S04 FDT- 27 Neoplasia 5 Clinical Aspects -10:50 2S Mini-Cases -10:50 2S04 FDT- 31 Neoplasia 9 Cell Cycle Regulation -10:50 2S04 BIOSTATS/EPI 1-10:50 2S04 BIOSTATS/EPI 2-11:50 2S04 FDT- 28 Neoplasia 6 Carcinogenesis/Hallmarks/ Tumor Suppressors 1-11:50 2S04 FDT- 29 Neoplasia 7 Tumor Suppressors 2-11:50 2S Mycology 1 Intro, Cutaneous Mycoses -11:50 2S04 FDT- 32 Neoplasia 10 DNA Repair Defects -11:50 2S04 FDT- 33 Neoplasia 11 Angiogenesis/Invasion/ Metastasis -6:00 TC COMPREHENSIVE BASIC SCIENCE SUBJECT EXAM (CBS SHELF EXAM) -2:20 2S04, 5ELabs Lab 7 Antibiotics - 2N72A M1 Fireside Chat (Optional) -2:20 8 Rooms ETHICS 6-1:50 2S04 Doc 1 Lecture Adolescent & Pediatric Patients - Autopsy Slide Review (Group 4-8

8 Block Week 7 13-May 14-May 15-May 16-May 17-May -8:50 2S04 GEN 13-9:50 2S Mycology 4 Opportunistic Mycoses 1-8:50 2S04 GEN 14-9:50 2S Mycology 5 Opportunistic Mycoses 2-8:50 2S04 GEN 15-9:50 2S04 GEN 16-8:50 2S04 GEN 17-9:50 2S Parasitology 1-8:50 TC QUIZ 5-9:50 2S Parasitology 2-10:50 2S04 BIOSTATS/EPI 3-12:20 2S04, 5ELabs 115 Case CONF Epi Case -10:50 2S04 BIOSTATS/EPI 4-11:50 2S04 FDT-PHARM 20 Anti-Neoplastic Agents General Approach to Treatment * NEW Lecture* -10:50 2S04 BIOSTATS/EPI 5-11:50 2S04 FDT-PHARM 21 Anti-Neoplastic Agents Overview * NEW in Block 3* -10:50 2S04 FDT- 34 Nutrition 1 Nutritional Disease -- Overview -11:50 2S04 FDT- 35 Nutrition 2 Nutritional Disease -10:50 2S Parasitology 3-11:50 2S04, 7ELabs FDT- 36 Laboratory 2-2:20 2S04, 5ELabs Lab 8 Fungi -3:20 2S04 CBS SHELF EXAM Results Discussion -2:20 8 Rooms ETHICS 7-5:00 Doc 1 Standardized Patients 2N72A, 2E69, 2S11, 2S13, 2S14, 2L48

9 Block Week 8 20-May 21-May 22-May 23-May 24-May -8:50 2S Parasitology 4-9:50 2S Parasitology 5-8:50 2S04 GEN 18-9:50 2S Parasitology 6-11:45 TC NBME Microbiology and Immunology Subject Exam -10:50 2S04 FDT- 37 Environmental Path 1-11:50 2S04 FDT- 38 Environmental Path 2-11:20 2S04, 5ELabs Lab 9 Parasites - EXAM 2-2:20 8 Rooms ETHICS 8 Secure Exam Review -

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