FUNDAMENTALS II 2012 Last revised: Date / Time Topic Faculty Reading
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1 WEEK 1 -- RESPONSE TO STRESS Macroscopic Rounds 3:15 pm 5:00 pm Nov. 12 Dec. 14 (student sign-up) Monday, October 29 8:10 Course Introduction Peter Anderson Ken Waites 9:10 Cell Adaptation Peter Anderson Robbins Ch. 1 10:10 Cell Injury Peter Anderson Robbins Ch. 1 11:10 The Autopsy Stephanie Reilly Self-Study Pathology Case Studies IPLAB 1 Cell Injury IPLAB 2 Cell Adaption IPLAB 1 & 2 Graded Quizzes Due Friday, December 7 th 9:00 a.m. Tuesday, October 30 MEDICAL STUDENT RESEARCH DAY Wednesday, October 31 8:10 Principles of Pharmacodynamics Dennis Pillion Katzung, Ch. 2 Receptor Pharmacology (Structure Activity Relationship) 9:10 Principles of Pharmacodynamics Dennis Pillion Katzung, Ch. 2 Signal Transduction 1 10:10 Principles of Pharmacodynamics Dennis Pillion Katzung, Ch. 2 Signal Transduction 2 (second messengers) 11:10 Environmental Pathology Greg Davis Robbins, Ch 9 Self Study Pathology Case Studies IPLab 12 Environmental IPLAB 12 Graded quiz Due Friday, December 7 th 9:00 a.m. Thursday, November 1 8:10 Complementary & Alternative Helen Kim Katzung, Ch. 64 Medicine - Nutraceuticals 9:10 Drug Interactions with Helen Kim Katzung, Ch. 63 Dietary Supplements 10:10 Novel Drug Targets 1 Mary-Ann Bjornsti Katzung, Ch :10 Novel Drug Targets 2 Mary-Ann Bjornsti Katzung, Ch. 54 Friday, November 2 9:10 Pharmacogenetics / Pharmacogenomics-I Nita Limdi 10:10 Pharmacogenetics / Pharmacogenomics-II Nita Limdi
2 WEEK 2 ABNORMAL GROWTH Monday, November 5 th 8:10 Regulatory Aspects of Drug Edward Acosta Katzung, Ch. 5 Development 9:10 Clinical Trials / Evidence Based Medicine Edward Acosta Katzung, Ch. 5 10:10 12:00 IPLAB Review Session (Labs 1 & 2) Peter Anderson 1:00p PHARMACOLOGY CASE 1 Session A Dennis Pillion, Ed Acosta Stephen Barnes, Mahmoud el Kouni Charles Falany, Helen Kim Jennifer King, John Parant Tuesday, November 6 th 11:10 IPLab Review Lab 12 Peter Anderson 1:00p PHARMACOLOGY CASE 1 Session B Dennis Pillion, Ed Acosta Stephen Barnes, Mahmoud el Kouni Charles Falany, Helen Kim Jennifer King, John Parant Self-Study Pathology Case Studies IPLAB 7 Neoplasia IPLAB 7 Graded Quiz Due Friday, December 7 th 9:00 a.m. Wednesday, November 7 th 9:10 11:00 Cancer Chemotherapy I & II Karina Yoon Katzung, Ch 54 Toy, Cases 48, 49, 50 11:10 Forensic Pathology Greg Davis Thursday, November 8 th 8:10 10:00 Neoplasia I and II Andra Frost Robbins, Ch 7 10:10 11:00 Pharmacology Review and Integration Dennis Pillion 11:10 12:00 Exam Prep Review Session & IPLAB 7 Peter Anderson Review Dennis Pillion Friday, November 9 th 8:00 12:00 n EXAMINATION 1 Covers content thru November 8 Computer Lab VH G077
3 WEEK 3 INFLAMMATION AND IMMUNITY Monday, November 12 th 8:10 Innate and Adaptive Immunity Louis Justement Kuby Ch 1 & 3 9:00 PHARMACOLOGY CASE 1 QUIZ ON PERCEPTION DUE 9:10-11:00 Cells of the Immune System I & II David Chaplin Kuby, Ch 2 11:10 Hemodynamics Peter Anderson Robbins, Ch 4 1:00p PHARMACOLOGY CASE 2 SESSION A Dennis Pillion, Stephen Barnes Mahmoud elkouni, Charles Falany Helen Kim, Jennifer King John Parant, Karina Yoon Self Study Pathology Case Studies IPLab 4 Hemodynamics IPLab 4 Graded Quiz Due Friday December 7 th 9:00 a.m. Immunology Cases 1 4 Immunology Graded Quizzes Due Tuesday, December 11 th 9:00 a.m. Tuesday, November 13 th 8:10-10:00 Antibodies I & II Peter Burrows Kuby, Ch 4&5 10:10 Cytokines & Inflammation Scott Barnum Kuby, Ch 13 11:10 Complement Scott Barnum Kuby, Ch 2 1:00 p PHARMACOLOGY CASE 2 SESSION B Dennis Pillion, Stephen Barnes Mahmoud elkouni, Charles Falany Helen Kim, Jennifer King, Karina Yoon Robert vanwaardenburg Wednesday, November 14 th 8:10 Phagocytic Cells & Phagocytosis Scott Barnum Kuby, Ch 7 9:10 Trafficking: Selectins, Integrins Scott Barnum Kuby, Ch 12 Chemokines 10:10-12:00 Inflammation I & II Peter Anderson Robbins, Ch 2 & 3 Self Study Pathology Case Studies IPLAB 3 Inflammation & Repair IPLAB 3 Graded Quiz Due Friday, December 7 th 9:00 a.m. Thursday, November 15 th 8:10 Antibody-Antigen Interactions & Assays Peter Burrows Kuby, Ch 6 9:10 MHC I & II Jim Collawn Kuby, Ch 8 10:10 Lymphocyte Activation Chandar Raman Kuby Ch 10 11:10 Modulation of Adaptive Immune Response Chandar Raman Friday, November 16 th 8:10 10:00 Childhood Diseases Keith Harrison Robbins, Ch 10 10:10 Anti-inflammatory Drugs Dennis Pillion Katzung Ch 36 (Steroidals and Non-steroidals) Toy Ch 19 11:10 Anti-gout drugs (uricemic & uricosuric) Dennis Pillion Katzung Ch 36 Self-Study Pathology Case Study IPLAB 13 Diseases of Infancy IPLAB 13 Graded Quiz Due Friday, December 7 th 9:00 a.m.
4 WEEK 4 Monday, November 19 th 8:10 Lab Medicine I Robert Hardy 9:00 PHARMACOLOGY CASE 2 QUIZ ON PERCEPTION DUE 9:10 Transplantation Immunology & Rejection James George 10:10 12:00 Genetic Diseases I & II Ona Faye Petersen Robbins, Ch 5 Self Study Pathology Case Studies IPLAB 5 Genetics IPLAB 5 Graded Quiz Due Friday, December 7 th 9:00 a.m. Tuesday, November 20 th 8:10-10:00 Lab Medicine II Robert Hardy 10:10 12:00 Immunopathology R. Pat Bucy Robbins, Ch 6 Self-Study Pathology Case Study IPLAB 6 Immunology IPLAB 6 Graded Quiz Due Friday, December 7 th 9:00 a.m. THANKSGIVING VACATION
5 WEEK 5 INFLAMMATION AND IMMUNITY Monday, November 26 th 8:10 10:00 Lab Medicine Case Review Robert Hardy With in-class GRADED QUIZ 10:10 Congenital Immunodeficiencies T. Prescott Atkinson Kuby, Ch 10 Pp :10 Acquired Immunodeficiencies T. Prescott Atkinson Kuby, Ch 10 Pp :00 p PHAMACOLOGY CASE 3 Session A Dennis Pillion, Steve Aller Stephen Barnes, Mary-Ann Bjornsti, Charles Falany, Helen Kim Jennifer King, Jeevan Prasain Tuesday, November 27 th 8:10a Hypersensitivity (Types I, II, III, IV) T. Prescott Atkinson Kuby Ch 15 Pp :10a Antihistamines, Vasoactive T. Prescott Atkinson Katzung Ch 16, Amines & Eicosanoids 17, 18 Toy Cases 24, :10-12:00 Autoimmunity I and II Winn Chatham Kuby, Ch 16 1:00 p PHARMACOLOGY CASE 3 Session B Dennis Pillion, Steve Aller Stephen Barnes, Mary-Ann Bjornsti, Charles Falany, Helen Kim Jennifer King, Robert vanwaardenburg Wednesday, November 28 th 8:10 Immunity to Infection Alan Zajac Kuby, Ch 18 & 19 9:10 Overview of Immunology Scott Barnum 10:10 Exam Prep Session Peter Anderson Ken Waites Dennis Pillion 11:10 p IPLab 4, 5 & 6 Review Session Peter Anderson Thursday, November 29 th 8:00 3:00 EXAMINATION 2 Covers content thru November 28 th Computer Lab VH G077 Friday, November 30 th Study for Infectious Diseases
6 WEEK 6 MICROBIOLOGY AND INFECTIOUS DISEASE Monday, December 3 rd 9:00 PHARMACOLOGY CASE 3 QUIZ ON PERCEPTION DUE 9:10 Overview of Infectious Diseases David Briles Murray, Ch 1 10:10 12:00n Bacterial Structure, Physiology & Janet Yother Murray, Ch 2, 3 Classification I & II 1:00 p.m. Bacterial Genetics Janet Yother Murray Ch 3 Self-Study Pathology Case Study IPLAB 9 Robbins Ch 8 Bacterial Diseases IPLAB 9 Graded Quiz Due Friday, December 14 th 9:00 a.m. Tuesday, December 4 th 9:10 Bacterial Pathogenesis & Virulence David Briles Murray, Ch 7, 18 10:10 12:00n Gram Positive Cocci Ken Waites Murray Ch 21, 22, 23 Wed, December 5 th 9:10 Rickettsia Edward Hook Murray Ch 42, :10 Spirochetes Edward Hook 11:10 Gram Positive Bacilli Ken Waites Murray Ch 14-17, 19 1:00 3:00 p.m. Gram-Negative Bacilli William Benjamin Murray, Ch Thursday, December 6 th 9:10 Mycobacteria William Benjamin Murray Ch 28 10:10 Neisseria & Chlamydia William Geisler Murray Ch 29, 46 11:10 Introduction to Diagnostic Microbiology Ken Waites Murray Ch :00 3:00 p.m. Microbiology Laboratory I & Quiz Ken Waites Microbiology Lab Introduction to Bacteriological Techniques Donna Crabb Syllabus LABORATORY QUIZ IN SESSION Friday, December 7 th 9:10 Anaerobic Bacteria Stephen Moser Murray Ch :10 Gram-negative Bacilli & Fastidious Bacteria Ken Waites Murray, Ch :10 Antibacterial Chemotherapy I: Craig Hoesley Katzung Ch 47,50 Disinfectants & Antimicrobials, 51 Antimycobacterial Drugs Murray Ch 8,20 1:00 p.m. Antibacterial Chemotherapy II: Martin Rodrigues Katzung Ch 43 Beta-lactams, Vancomycin, Linezolid Toy Case 45 Daptomycin, Metronidazole
7 WEEK 7 MICROBIOLOGY AND INFECTIOUS DISEASE Monday, December 10 th 9:10 Fungal Pathogens Stephen Moser Robbins Ch 8 10:10 Antifungal Drugs John Baddley Katzung Ch 48 Toy Case 47 Murray Ch 6, 70 11:10 Antibacterial Chemotherapy III: John Gnann Katzung, Ch 44, Aminoglycosides, Quinolones, Sulfonamides, 45, 46 Tetracyclines, Macrolides, Clindamycin 1:00 p.m. Drug Resistance Ken Waites Murray Ch 5, 67 69, Self-Study Pathology Case Study IPLAB 10 Fungal Diseases IPLAB 10 Graded Quiz Due Friday, December 14 th 9:00 a.m. Tuesday, December 11 th 9:00 Immunology Case 1-4 Quizzes Due 10:10 Intestinal Protozoa Amoebae, Giardia William Benjamin Murray Ch 81 Cryptosporidium, Trichomonas 11:10 Intestinal & Tissue Helminths Cestodes William Benjamin Murray Ch Nematodes, Trematodes Self-Study Pathology Case Study IPLAB 11 Parasitic Diseases IPLAB 11 Graded Quiz Due Friday, December 14 th 9:00 a.m. Wed, December 12 th 9:10 Aging and Susceptibility to Infection Donna Bearden Katzung, Ch 60 Geriatric Pharmacology 10:10 IPLAB Review Lab 9 & 10 Ken Waites 11:10 Hemoflagellates Leishmania, William Benjamin Murray Ch 82 Trypanosoma, Toxoplasma 1:00 3:00 p.m. Microbiology Laboratory II & Quiz Ken Waites Microbiology Lab Physician Office Microbiology & Donna Crabb Syllabus Parasitology Murray Ch 79 LABORATORY QUIZ IN LAB SESSION Thursday, December 13 th 9:10 Malaria William Benjamin Murray Ch 82 10:10 Anti-parasitic & Anti-protozoal Drugs Mahmoud el Kouni Katzung Ch 52 Murray Ch 80 11:10 Anti-Helminthic Drugs Mahmoud el Kouni Katzung Ch 54 1:00 p.m. Viruses Structure, Classification, Peter Prevelige Murray Ch 4, 48 Detection and Quantitation 50 Self Study Pathology Lab Cases IPLAB 8 Viral Disease Virology Cases 1 & 2 IPLAB 8 Graded Quiz Due Tuesday, December 18 th 9:00 a.m. VIROLOGY CASES 1 & 2 Graded Quiz Due Tuesday, December 18 th 9:00 a.m. Friday, December 14 th 9:00 IPLAB Graded Quizzes 9, 10, & 11 DUE 9:10 Viral Replication Casey Morrow Murray Ch 4 10:10 Tumor Viruses & Oncogenes Casey Morrow Murray Ch 68 11:10 Virus Host Interactions Alan Zajac Murray Ch 48 1:00 p.m. IPLAB REVIEW Labs 8 & 11 Ken Waites
8 WEEK 8 MICROBIOLOGY AND INFECTIOUS DISEASE Monday, December 17 th 9:10 Retroviruses / HIV Michael Saag Murray Ch 64 10:10 Antiviral Chemotherapy /AIDS Drugs Michael Saag Katzung Ch 49 Toy Case 46 Murray Ch 40 11:10 Hepatitis Viruses William Benjamin Murray Ch 65 1:00 p.m. Paramyxovirus Sonya Heath 2:00 p.m. Pharmacology Case 4 Session A Dennis Pillion, Ed Acosta Mahmoud el Kouni, Charles Falany Helen Kim, Jennifer King Jeevan Prasain Tuesday, December 18 th 9:00 IPLAB Graded Quiz 8 DUE Virology Cases 1-2 Quizzes Due 9:10 Enterviruses / Rhinoviruses Casey Morrow Murray Ch 56 10:10 Vector Borne Viruses John Gnann Murray Ch 62,63 11:10 Papillomaviruses Tom Broker Murray Ch 51 1:00 p.m. Orthomyxoviruses Sonya Heath Murray Ch 59 2:00 p.m. Pharmacology Case 4 Session B Dennis Pillion, Ed Acosta Mahmoud el Kouni, Charles Falany Helen Kim, Jennifer King Jeevan Prasain Wed, December 19 th 9:10 Adenoviruses Jeffrey Engler Murray Ch 52 10:10 12:00n Herpesviruses I & II Kevin Cassady Murray Ch 53 1:00 p.m. Emerging Viral Diseases David Freedman Murray Ch 57,60 Thursday, December 20 th 9:00 PHARMACOLOGY CASE 4 QUIZ ON PERCEPTION DUE 9:10 Infection Control, Vaccines & Public Health Paul Goepfert Murray Ch 13 10:10-12:00n Pathology of Infectious Disease Ken Waites Robbins Ch 8 Review I & II Murray Ch 47, 48 50, 66-68, 77, 78, 87 1:00 p.m. Exam Prep Review Peter Anderson Ken Waites Friday, December 21 st 8:00 4:00P FINAL EXAM
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