Particle Therapy Systems by Mitsubishi Electric DG1101-KM-0034
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1 Particle Therapy Systems by Mitsubishi Electric DG1101-KM-0034 Saudi-Japan Business Opportunities Forum February 1 2,
2 2
3 Types of Treatment Conventional Radiation Therapy Uses photons (energetic X rays, ~6MV) Particle - Therapy Proton Therapy ( 60% speed of light) Hydrogen Gas H p Carbon Therapy ( 70% speed of light) CO 2 Gas C 12 C
4 Mechanism Cells die when photon, photon, proton or carbon beam breaks the DNA inside. Carbon has a larger Biological Effect on cells, compared to photon or proton. 4
5 Bragg Peak Particles (proton and carbon) have a Bragg Peak. Photons don t. SOBP=Spread-Out Bragg Peak (photon) (photon) Cells Die Cells Live 5
6 No. of Dedicated PTS Facilities Proton Carbon Dual Japan Other Asia US EU Operating Under construction 6
7 Particle Therapy Facilities in Japan C Gunma University Heavy Ion Medical Center Treatment since March 2010 P Southern Tohoku Proton Therapy Cancer Center Treatment since October 2008 P: Proton C: Carbon P Fukui Proton Therapy Center Treatment since March 2011 National Institute of Radiological Sciences Treatment since June 1994 P C Saga Heavy Ion Medical Accelerator in Tosu Open in 2013 (under construction) Medipolis Proton Therapy & Research Center Treatment since January 2011 P C Hyogo Ion Beam Medical Center Treatment since April 2003 Shizuoka Cancer Center Treatment since October 2003 P 7
8 Facility Southern Tohoku Proton Therapy Cancer Center Proton Medical Research Center Univ. of Tsukuba National Cancer Center (Kashiwa) Sites Treated by Particle Therapy (2009) Head & Neck Data: Yomiuri Shimbun Newspaper, June 6, 2010 Lung Prostate Liver Other Total Esophagus Pediatric Shizuoka Cancer Center Brain Tumor Hyogo Ion Beam Medical Center NIRS HIMAC Bone &Soft tissue 96 Lower Intestine
9 Dual Product Line Up Mitsubishi Electric is the only vendor in the world with a Government-approved Carbon solution and a Dual solution. Proton Hyogo Ion Beam Medical Center Shizuoka Cancer Center Southern Tohoku Proton Therapy Cancer Center Medipolis Proton Therapy & Research Center Fukui Proton Therapy Center Carbon Gunma University Heavy Ion Medical Center Saga Heavy Ion Medical Accelerator in Tosu* * Under construction 9
10 Carbon Beam Facility Gunma University Heavy Ion Medical Center Saga Heavy Ion Medical Accelerator in Tosu Under Construction 10
11 Carbon Beam Facility Vertical and Horizontal Ports 46m Beam Transport Line Horizontal Port Synchrotron R&D Port Vertical Port Injector Linac PET-CT CT Simulator MRI Gunma University Heavy Ion Medical Center 76m Total floor space 6,280m 2 Synchrotron circumference Treatment Ports Beam 63m H x1, V x1 H+V x1 Carbon MeV/u 11
12 Carbon Beam Synchrotron 63m Gunma University Heavy Ion Medical Center 12
13 Proton-Carbon Dual Facility Hyogo Ion Beam Medical Center 13
14 Beam Transport Line Treatment Rooms Synchrotron Gantry Injector Linac Hyogo Ion Beam Medical Center 14
15 Proton-Carbon Dual Synchrotron 93m Hyogo Ion Beam Medical Center 15
16 Proton Beam Facility Shizuoka Cancer Center Southern Tohoku Proton Therapy Cancer Center Fukui Proton Therapy Center Medipolis Proton Therapy & Research Center 16
17 陽子専用施設 (3G) 72m 31m Medipolis Proton Therapy & Research Center 17
18 3 Gantry Can deliver the treatment beam from any angle Beam Transport 18
19 4Treatment Room Beam delivery nozzle and high-accuracy patient positioning Beam Delivery 19
20 プリンタ 3 次元計測器 照射器具加工機 Particle Therapy System X-ray imaging system in 2 orthogonal views Beam Delivery Nozzle X ray CT for Treatment Planning デジタイザ Digitizer UPS UPS Laser レーザプprinter リンタ ジュー Jukebox クボックス 治療計画端末 Terminal A A Printer 治療計画端末 Terminal B 画像 Image フュー Fusion ジョン端末 PostScript Postscript 治療情報管理サーバ Treatment Terminal 対応 RIP Information Server RAID プPrinter リンタ Ethernet 3D 3 次 Measurement 元測定機端末ベ Base ースユUnit ニット CAD/CAM 端末ベー Base スユUnit ニット Terminal Terminal バ Bar ーコー Code ト 発 Admin. 券端末 バ Bar ー Code コート プPrinter リンタ 無 Wireless 線 I/F 無 Wireless 線 I/F I/F 3D Measurement Bar ハ ーコート Code Reader リータ Machining Tool Bar ハ ーコート Code リータ Reader スSlides ライド作 for 成機 presentation X-ray Image Processing for Patient Positioning Treatment Delivery and Control System Treatment Planning System 20
21 New Development 1 Beam delivery: Improved dose distribution, better conformity to the tumor shape Broad Beam Layer Stacking Pencil Beam Scanning Wobbler Magnets Collimator Bolus Important Features Beam is quickly irradiated over the whole volume Beam is irradiated in layers The volume is painted with a narrow pencil beam Fast control of beam position and intensity Safety Delivered Dose 21
22 New Developments 2 Extend the PTS application to soft area such as breast CT images are taken prior to beam treatment. Target positioning is based on automatic recognition of the internal volume. Mammary gland recognition using CT images. (Simulation result) 22
23 New Design 23
24 Closing Remarks Particle therapy is a treatment method intended for less pain and a better Quality of Life. Many facilities are now under construction worldwide. We feel that starting up particle therapy will greatly benefit the people of Saudi Arabia. Mitsubishi Electric, as the leading Japanese PTS vendor of PTS, would be honored to be a part of such a project. 24
25 Thank you for your attention 25
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