New Treatment Research Facility Project at HIMAC
|
|
|
- Lauren Young
- 5 years ago
- Views:
Transcription
1 New Treatment Research Facility Project at Koji Noda Research Center for Charged Particle Therapy National Institute of Radiological Sciences IPAC10, Kyoto, JAPAN, 25th May, 2010
2 Contents 1. Introduction 2. Design and specifications 3. Overview of project status 4. Summary
3 Introduction Physical Advantage of Heavy Ion High longitudinal dose localization due to the Bragg peak. 5 4 Lateral biological dose distribution C proton Relative dose (%) Dose (GyE) lateral position (cm) Depth in water (cm) C ion n gam m a-ray proton High transverse dose localization due to the low scattering.
4 Biological Advantage Introduction RBE,O E R H RBE OER C Si LET LET (kev (kev/μm) /μ) LET dependence on RBE, OER Biological Dose (GyE) Biological Depth-Dose Distribution of 6cm SOBP Normal tissue Tumor Depth in Water He C Ne Proton
5 Milestone of Radiotherapy Introduction 1984: Heavy ion therapy project started under National Comprehensive 10-year Strategy for Cancer Control : Construction of : Carbon-ion RT started at 21 st June : approved Highly Advanced Medical Technology : Design and R&D for Downsized C-ion RT Facility : Construction of Pilot Facility at Gunma Uni : 1 st Patient treated at Gunma at 16 th March : New Treatment Research Facility Project for further development of treatment.
6 Introduction facility Ion species: High LET (100keV/μm) charged particles He, C, Ne, Si, Ar Range: 30cm in soft tissue 800MeV/u (Si) Maximum irradiation area: 22cmΦ Dose rate: 5Gy/min Beam direction: horizontal, vertical (Heavy Ion Medical Accelerator in Chiba)
7 Milestone of Radiotherapy Introduction 1984: Heavy ion therapy project started under National Comprehensive 10-year Strategy for Cancer Control : Construction of : Carbon-ion RT started at 21 st June : approved Highly Advanced Medical Technology : Design and R&D for Downsized C-ion RT Facility : Construction of Pilot Facility at Gunma Uni : 1 st Patient treated at Gunma at 16 th March : New Treatment Research Facility Project for further development of treatment.
8 Progress of treatment number Introduction Num of Treatments Treatment Period: 43 wks 1st Term(Apr Aug): 18.5wks 2nd Term(Sept Feb):24.5wks Treatment: 4 days per week FY
9 Milestone of Radiotherapy Introduction 1984: Heavy ion therapy project started under National Comprehensive 10-year Strategy for Cancer Control : Construction of : Carbon-ion RT started at 21 st June : approved Highly Advanced Medical Technology : Design and R&D for Downsized C-ion RT Facility : Construction of Pilot Facility at Gunma Uni : 1 st Patient treated at Gunma at 16 th March : New Treatment Research Facility Project for further development of treatment.
10 4. Compact Facility Gunma University Heavy-Ion Medical Center Treatment Room Synchrotron 10Ghz-ECR Injector Linac APF-IH
11 Milestone of Radiotherapy Introduction 1984: Heavy ion therapy project started under National Comprehensive 10-year Strategy for Cancer Control : Construction of : Carbon-ion RT started at 21 st June : approved Highly Advanced Medical Technology : Design and R&D for Downsized C-ion RT Facility : Construction of Pilot Facility at Gunma Uni : 1 st Patient treated at Gunma at 16 th March : New Treatment Research Facility Project for further development of treatment.
12 Introduction Motivation therapy needs to be upgraded. Upgrading irradiation system - raster scanning system - rotating gantry system Upgrading control system Upgrading patient handling system Upgrading treatment planning system Further development of heavy-ion therapy - Adaptive therapy - Intensity modulated Ion Therapy (IMIT) New facility Hospital New treatment facility project
13 Introduction Motivation ~ adaptive therapy Intra & interfractional changes from time resolved imaging (seconds to days) using CT/FPD devices could be feed-back to the treatment planning. The rich information could extend to replan, 4D plan and patient registration etc.
14 Introduction Motivation ~ IMIT IMIT plan example 0 deg 0 d e g Gantry with 3D scanning makes it possible to realize Intensity Modulated Ion Therapy (IMIT). 288 deg 72 deg Volume [%] PTV IMIT PTV Sngl GTV IMIT GTV Sngl CRD IMIT CRD Sngl Dose [%] 216 deg 144 deg - Improved dose conformity and steeper dose gradients - Further reduction of integral dose - Less sensitivity to range uncertainties and other sources of uncertainty
15 Contents 1. Introduction 2. Design and specifications 3. Overview of project status 4. Summary
16 Design & Spec Design and specifications New facility 1. Ion species: 12C, 16O (11C, 15O) 2. Irradiation method: Hybrid raster scanning 3. Range: ~ 30cm in water 4. Maximum irradiation area: 22cm square 5. Delivered Intensity: pps (for C ions) 6. Treatment rooms: 3 = 2 H&V + 1 rotating gantry
17 3D Scanning Method R&D Work Adaptive Therapy by 3D Scanning 1) Beam utilization efficiency 100% 2) Irradiation on irregular shape target 3) No bolus & collimator 1) Sensitive beam error 2) Longer irradiation time 3) Sensitive to organ motion Scanner Monitor Range Shifter Beam Dose distribution of pencil beam
18 3D Scanning Method R&D Work Adaptive Therapy by 3D Scanning Rescanning with Gated Irradiation ) Beam utilization efficiency 100% -40 2) Irradiation on irregular shape target 3) No bolus &-20 collimator ) Sensitive beam 0 error 2) Longer irradiation time 20 3) Sensitive to organ motion 40 Scanner Monitor Range 1.1 Shifter 1.1 Beam Dose distribution of pencil beam
19 Fast 3D Scanning Design & Spec In order to realize the rescanning with gating within acceptable irradiation time, we have studied following strategy. 1. Treatment planning for fast scanning 5 2. Modification of acc. operation 2 3. Fast scanning magnet times speed up!! (A) 50 y (m m ) x (m m ) 50 (B) (C)
20 Design & Spec Fast scanning system 3D scanning irradiation Max field size 220 mm 2 Max SOBP 150 mm Max energy 430 MeV/u Moving target OK beam size 3~6 mm (1σ) Ene. change RSF Design and R&D work were carried out. Vertical line Horizontal line Room E Beam test : Dec ~ Feb. 2010
21 Design & Spec Fast scanning system Design and R&D work were carried out. Vertical line Horizontal line Room E Beam test : Dec ~ Feb. 2010
22 Design & Spec Fast scanning system Design and R&D work were carried out. Vertical line Scanning Magnet Horizontal line Room E Beam test : Dec ~ Feb. 2010
23 Design & Spec Fast scanning system Design and R&D work were carried out. Vertical line Pos. Moni. Horizontal line Dose Moni Room E Beam test : Dec ~ Feb. 2010
24 Design & Spec Fast scanning system Design and R&D work were carried out. Vertical line Range Shifter Horizontal line Room E Beam test : Dec ~ Feb. 2010
25 Design & Spec Gantry design 1) IMIT 2) Reduction of Patient s Load 3D scanning irradiation Max field size 150 mm 2 Max SOBP 150 mm Max energy 430 MeV/u Moving target OK beam size 3~6 mm (1σ) Ene. change RSF Total weight 350 ton
26 Design & Spec Floor plan Treatment rooms : 3 Simulation rooms : 2 Preparation rooms: 6
27 Contents 1. Introduction 2. Design and specifications 3. Overview of project status 4. Summary
28 Building Overview Mar. 2010, new treatment building construction has been completed.
29 Building Overview April, 2010 Mar. 2010, new treatment building construction has been completed.
30 Overview Treatment room / Simulation room Simulation room Treatment room
31 Overview Treatment room / Simulation room Simulation room Treatment room April, 2010
32 Overview Treatment Hall Entrance Preparation room
33 Overview Treatment Hall Entrance Preparation room
34 Overview Beam line devices Beam line dipole magnet Quadrupole magnet Installation of devices is in progress.
35 Contents 1. Introduction 2. Design and specifications 3. Overview of project status 4. Summary
36 Summary Summary Construction of the building is completed. Performance of 3D rescanning is verified. Installation & commissioning will be carried out in this year. First patient is scheduled in next March.
37 Acknowledgement Thank you for your attention
Review of Heavy Ion Accelerators for Hadrontherapy
Review of Heavy Ion Accelerators for Hadrontherapy Koji Noda Research Center for Charged Particle Therapy National Institute of Radiological Sciences 11 th Int l Conf. on Heavy Ion Accelerator Technology,
Cancer Treatment by Charged Particles - Carbon Ion Radiotherapy -
Cancer Treatment by Charged Particles - Carbon Ion Radiotherapy - Takeshi Murakami Research Center of Charged Particle Therapy National Institute of Radiological Sciences 2012.11.21 1. Introduction to
Review of Hadron machines for cancer therapy
Review of Hadron machines for cancer therapy M. Kanazawa NIRS cancer therapy with hadron (p, C) Clinical studies at New ideas of accelerators Compact facilities (p, C) Depth dose distribution Carbon, proton
Heavy Ion Tumor Therapy
Heavy Ion Tumor Therapy Applications Bence Mitlasoczki 25.06.2018 Heidelberg 1. Source (H 2 /CO 2 ) 2. Linac 3. Synchrotron 4. Guide 5. Treatment rooms 6. X-ray system 7. Gantry 8. Treatment room with
Radiation qualities in carbon-ion radiotherapy at NIRS/HIMAC
Radiation qualities in carbon-ion radiotherapy at NIRS/ Shunsuke YONAI Radiological Protection Section Research Center for Charged Particle Therapy National Institute of Radiological Sciences (NIRS) E-mail:
The Advantages of Particle Therapy and the Status of the Heidelberg Iontherapy Center
The Advantages of Particle Therapy and the Status of the Heidelberg Iontherapy Center Thomas Haberer, Scientific Technical Director, Heidelberg Ion Therapy Center Situation / Indications 2/3 patients suffer
The Heidelberg Ion Therapy Center. Thomas Haberer Heidelberg Ion Therapy Center Hadron Therapy Workshop, Erice 2009
The Heidelberg Ion Therapy Center Thomas Haberer Heidelberg Ion Therapy Center Hadron Therapy Workshop, Erice 2009 Goal The key element to improve the clinical outcome is local l control! entrance channel:
Progress of Heavy Ion Therapy
Progress of Heavy Ion Therapy Fuminori Soga Division of Accelerator Physics and Engineering, National Institute of Radiological Sciences, 4-9-1 Anagawa. Inage-ku, Chiba 263-8555, Japan 1. Introduction
T.Kanai, K. Yusa, M. Tashiro, H. Shimada, K. Torikai, Gunma University, Gunma, Japan
The carbon-ion cancer therapy facility at Gunma University T.Kanai, K. Yusa, M. Tashiro, H. Shimada, K. Torikai, J. Koya, T. Ishii, Y. Yoshida, S. Yamada, T. Ohno, T. Nakano Gunma University, Gunma, Japan
Characterization and implementation of Pencil Beam Scanning proton therapy techniques: from spot scanning to continuous scanning
Characterization and implementation of Pencil Beam Scanning proton therapy techniques: from spot scanning to continuous scanning Supervisors Prof. V. Patera PhD R. Van Roermund Candidate Annalisa Patriarca
The Heidelberg Ion Therapy (HIT) Accelerator Coming Into Operation. Presented at EPAC 2008, Genova D. Ondreka, GSI
The Heidelberg Ion Therapy (HIT) Accelerator Coming Into Operation Presented at EPAC 2008, Genova D. Ondreka, GSI Introduction Heidelberg Ion Therapy Centre: Europe's first dedicated particle therapy facility
SUMITOMO Particle Therapy Technologies
55 th AAPM annual meeting Particle Beam Therapy Symposium SUMITOMO Particle Therapy Technologies August 3, 2013 Yukio Kumata Experience accelerators for science Current Status proton and carbon Future
Proton and heavy ion radiotherapy: Effect of LET
Proton and heavy ion radiotherapy: Effect of LET As a low LET particle traverses a DNA molecule, ionizations are far apart and double strand breaks are rare With high LET particles, ionizations are closer
*Chien-Yi Yeh, Ji-Hong Hong * 葉健一洪志宏
林口 Proton Therapy in Ti Taiwan *Chien-Yi Yeh, Ji-Hong Hong * 葉健一洪志宏 Chang Gung Memorial Hospital at Lin-Kou, Taiwan 林口長庚紀念醫院 OCPA2010 at Beijing, China Aug. 5, 2010 Outline 1. The principle of proton radiotherapy
Ion Beam Therapy should we prioritise research on helium beams?
Ion Beam Therapy should we prioritise research on helium beams? Stuart Green Medical Physics University Hospital Birmingham NHS Trust Follow-up from the EUCARD2 workshop, ION Beam Therapy: Clinical, Scientific
The Heidelberg Ion Therapy Center and PARTNER. Thomas Haberer Heidelberg Ion Therapy Center
The Heidelberg Ion Therapy Center and PARTNER Thomas Haberer Heidelberg Ion Therapy Center Goal The key element to improve the clinical outcome is local control! entrance channel: low physical dose low
State-of-the-art proton therapy: The physicist s perspective
State-of-the-art proton therapy: Tony Lomax, Centre for Proton Radiotherapy, Paul Scherrer Institute, Switzerland Overview of presentation 1. State-of-the-art proton delivery 2. Current challenges 3. New
Particle Therapy Systems by Mitsubishi Electric DG1101-KM-0034
Particle Therapy Systems by Mitsubishi Electric DG1101-KM-0034 Saudi-Japan Business Opportunities Forum February 1 2, 2012 1 2 Types of Treatment Conventional Radiation Therapy Uses photons (energetic
Present status and future of Proton beam therapy
Present status and future of Proton beam therapy Description At present, the types of proven treatment for cancer are surgery, radiotherapy, and chemotherapy. Depending on the characteristics of cancer
Proton Treatment. Keith Brown, Ph.D., CHP. Associate Director, Radiation Safety University of Pennsylvania
Proton Treatment Keith Brown, Ph.D., CHP Associate Director, Radiation Safety University of Pennsylvania Proton Dose vs. Depth Wilson,. R.R. Radiological use of fast protons. Radiology 47:487-491, 1946.
HIMAC AND MEDICAL ACCELERATOR PROJECTS IN JAPAN
HIMAC AND MEDICAL ACCELERATOR PROJECTS IN JAPAN S. Yamada, T. Honma, M. Kanazawa, A. Kitagawa, S. Kouda, M. Kumada, T. Murakami, M. Muramatsu, T. Nishio, K. Noda, Y. Sato, M. Suda and E. Takada, Research
III. Proton-therapytherapy. Rome SB - 5/5 1
Outline Introduction: an historical review I Applications in medical diagnostics Particle accelerators for medicine Applications in conventional radiation therapy II III IV Hadrontherapy, the frontier
COMPARISON OF RADIOBIOLOGICAL EFFECTS OF CARBON IONS TO PROTONS ON A RESISTANT HUMAN MELANOMA CELL LINE
COMPARISON OF RADIOBIOLOGICAL EFFECTS OF CARBON IONS TO PROTONS ON A RESISTANT HUMAN MELANOMA CELL LINE I. Petrovi a, A. Risti -Fira a, L. Kori anac a, J. Požega a, F. Di Rosa b, P. Cirrone b and G. Cuttone
ABSTRACTS. of the NIRS International Seminar on the Heavy Charged Particle Therapy for Cancer and the XXVII PTCOG MEETING.
P ROTON THERAPY C O- OPERATIVE GROUP Chair Michael Goitein Ph. D. Department of Radiation Oncology Massachusetts General Hospital Boston MA 02114 (617) 724-9529 (617) 724-9532 Fax Secret ary Janet Sisterson
Basic Press Information
Basic Press Information Contact MedAustron EBG MedAustron GmbH Marie Curie-Strasse 5 A-2700 Wiener Neustadt Austria T +43 2622 26 100-0 e-mail: office@medaustron.at Internet: www.medaustron.at Press contact:
ACCELERATORS FOR HADRONTHERAPY
ACCELERATORS FOR HADRONTHERAPY Alberto Degiovanni CERN-BE IVICFA s Fridays: Medical Physics Valencia, 31.10.2014 Introduction: the icon of hadrontherapy Position of the Bragg peak depends on beam energy
IMPT with Carbon Ions
IMPT with Carbon Ions PTCOG 48, Heidelberg, 28.09.-03.10.2009 Malte Ellerbrock Medical Physics Expert Heidelberg Ion-Beam Therapy Center HIT Betriebs GmbH am Universitätsklinikum Heidelberg http://www.hit-centrum.de
Prof. Dr. Thomas Haberer Scientific-technical Director Heidelberg Iontherapy Center
The Heidelberg Ion Beam Therapy Center A Hospital-based Facility Dedicated to Precision and Flexibility Prof. Dr. Thomas Haberer Scientific-technical Director Heidelberg Iontherapy Center Carbon Ion Therapy
OPERATION AND PATIENT TREATMENTS AT CNAO FACILITY
OPERATION AND PATIENT TREATMENTS AT CNAO FACILITY Abstract The CNAO (National Centre for Oncological Hadrontherapy) has been realized in Pavia. It is a clinical facility created and financed by the Italian
Status of H 1 and C 12
Status of H 1 and C 12 Herman Suit No Conflict of Interest 1 Goal of a New Treatment Modality Tumor Control Probability or No in Complication Rate 2 Truism No Advantage to: any Patient for any Radiation
PROGRESS IN HADRONTHERAPY
PROGRESS IN HADRONTHERAPY Saverio Braccini TERA Foundation for Oncological Hadrontherapy IPRD06 - Siena - 01.10.06 - SB 1 Outline Introduction Radiation therapy with X rays and hadrontherapy Hadrontherapy
PHYS 383: Applications of physics in medicine (offered at the University of Waterloo from Jan 2015)
PHYS 383: Applications of physics in medicine (offered at the University of Waterloo from Jan 2015) Course Description: This course is an introduction to physics in medicine and is intended to introduce
SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENT OF HADRONTHERAPY
SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENT OF HADRONTHERAPY SAVERIO BRACCINI * Albert Einstein Centre for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse
Learning Objectives. Clinically operating proton therapy facilities. Overview of Quality Assurance in Proton Therapy. Omar Zeidan
Overview of Quality Assurance in Proton Therapy Omar Zeidan AAPM 2012 Charlotte, NC July 30 st, 2012 Learning Objectives Understand proton beam dosimetry characteristics and compare them to photon beams
Proton Therapy Dosimetry & Clinical Implementation. Baldev Patyal, Ph.D., Chief Medical Physicist Department of Radiation Medicine
Proton Therapy Dosimetry & Clinical Implementation Baldev Patyal, Ph.D., Chief Medical Physicist Department of Radiation Medicine Outline» Proton Therapy Basics» Why Proton Therapy? (Dosimetric Superiority)»
PTCOG 46. Educational Workshop Session IV. Head & Neck CLINICAL. J. Mizoe (NIRS, Japan)
PTCOG 46 Educational Workshop Session IV CLINICAL Head & Neck J. Mizoe (NIRS, Japan) Photon X-Ray γ-ray Fast Neutron Non-Charged Radiation Electron Proton Helium Light Ion Heavy Particle Carbon Neon Argon
Nuclear Data for Radiation Therapy
Symposium on Nuclear Data 2004 Nov. 12, 2004 @ JAERI, Tokai Nuclear Data for Radiation Therapy ~from macroscopic to microscopic~ Naruhiro Matsufuji, Yuki Kase and Tatsuaki Kanai National Institute of Radiological
Biological Optimization of Hadrontherapy. Uwe Oelfke
4/2/2012 page 1 Biological Optimization of Hadrontherapy Uwe Oelfke DKFZ Heidelberg (E040) Im Neuenheimer Feld 280 69120 Heidelberg, Germany u.oelfke@dkfz.de 4/2/2012 page 2 Contents Introduction and General
Specifics of treatment planning for active scanning and IMPT
Specifics of treatment planning for active scanning and IMPT SFUD IMPT Tony Lomax, Centre for Proton Radiotherapy, Paul Scherrer Institute, Switzerland Treatment planning for scanning 1. Single Field,
FROM ICARO1 TO ICARO2: THE MEDICAL PHYSICS PERSPECTIVE. Geoffrey S. Ibbott, Ph.D. June 20, 2017
FROM ICARO1 TO ICARO2: THE MEDICAL PHYSICS PERSPECTIVE Geoffrey S. Ibbott, Ph.D. June 20, 2017 1 DISCLOSURES My institution holds Strategic Partnership Research Agreements with Varian, Elekta, and Philips
HEAVY PARTICLE THERAPY
HEAVY PARTICLE THERAPY DR. G.V. GIRI KIDWAI MEMORIAL INSTITUTE OF ONCOLOGY ICRO 2012 BHATINDA HEAVY PARTICLES USED IN A EFFORT TO IMPROVE TUMOR CONTROL, THAT DO NOT RESPOND TO PHOTONS OR ELECTRONS BETTER
Introduction to Ion Beam Cancer Therapy
Introduction to Ion Beam Cancer Therapy Andrew M. Sessler (with some slides from David Robin) Lawrence Berkeley National Laboratory Berkeley, CA 94720 Cyclotron 10, Lanzhou September 10, 2010 Contents
Look! Borg get upgrade already!
Cancer, Partikel Terapi and PT accelerators Look! Borg get upgrade already! 1 Cancer, Partikel Terapi and PT accelerators Basic requirements to PT accelerator Accelerators for PT Siemens PT maskinen Alternativer:
Tumor Therapy with Heavy Ions at GSI Darmstadt
Tumor Therapy with Heavy Ions at GSI Darmstadt D. Schardt 1) for the Heavy Ion Therapy Collaboration 2) 1) Gesellschaft für Schwerionenforschung (GSI), Darmstadt, Germany 2) GSI Darmstadt / Radiologische
Assistant Professor Department of Therapeutic Radiology Yale University School of Medicine
A Mechanism-Based Approach to Predict Relative Biological i Effectiveness and the Effects of Tumor Hypoxia in Charged Particle Radiotherapy David J. Carlson, Ph.D. Assistant Professor Department of Therapeutic
A brief presentation of The TERA Foundation
A brief presentation of The TERA Foundation David Watts on behalf of Prof. Ugo Amaldi and all my colleagues at TERA TERA Overview Direction: Prof. Ugo Amaldi AQUA (Advanced QUAlity Assurance) Cyclinac
MEDICAL PHYSICS ASPECTS OF PARTICLE THERAPY Oliver Jäkel 1,2, *
Radiation Protection Dosimetry (2009), Vol. 137, No. 1 2, pp. 156 166 Advance Access publication 14 October 2009 doi:10.1093/rpd/ncp192 MEDICAL PHYSICS ASPECTS OF PARTICLE THERAPY Oliver Jäkel 1,2, * 1
PRESCRIBING RECORDING AND REPORTING PROTON BEAM THERAPY ICRU 78. RAJESH THIYAGARAJAN Senior Medical Physicist & RSO Medanta The Medicity
PRESCRIBING RECORDING AND REPORTING PROTON BEAM THERAPY ICRU 78 RAJESH THIYAGARAJAN Senior Medical Physicist & RSO Medanta The Medicity HISTORY OF PROTON THERAPY Robert Wilson proposed the use of proton
Research on Cancer Therapy with Carbon Beams Development of Human Friendly Cancer Therapy with Carbon Ion Beams
Research on Cancer Therapy with Carbon Beams Development of Human Friendly Cancer Therapy with Carbon Ion Beams Tadashi Kamada, M.D., Ph.D. Director of Research Center for Charged Particle Therapy E-mail:
Discuss the general planning concepts used in proton planning. Review the unique handling of CTV / ITV / PTV when treating with protons
Mark Pankuch, PhD Discuss the general planning concepts used in proton planning Review the unique handling of CTV / ITV / PTV when treating with protons Pencil Beam distributions and PBS optimization Cover
Uncertainties in proton therapy: Analysis of the effects of density changes, calibration curve errors and setup errors in proton dose distributions.
Uncertainties in proton therapy: Analysis of the effects of density changes, calibration curve errors and setup errors in proton dose distributions. A treatment planning study performed on water phantoms
Peak temperature ratio of TLD glow curves to investigate the spatial variation of LET in a clinical proton beam
Peak temperature ratio of TLD glow curves to investigate the spatial variation of LET in a clinical proton beam University of Chicago CDH Proton Center LET study C. Reft 1, H. Ramirez 2 and M. Pankuch
ADVANCES IN RADIATION TECHNOLOGIES IN THE TREATMENT OF CANCER
ADVANCES IN RADIATION TECHNOLOGIES IN THE TREATMENT OF CANCER Bro. Dr. Collie Miller IARC/WHO Based on trends in the incidence of cancer, the International Agency for Research on Cancer (IARC) and WHO
Future upcoming technologies and what audit needs to address
Future upcoming technologies and what audit needs to address Dr R.I MacKay History of audit Absolute dose - Simple phantom standard dose measurement Point doses in beams - Phantoms of relatively simple
Activities at the Heidelberg Ion Therapy Center (HIT)
Activities at the Heidelberg Ion Therapy Center (HIT) The people A. Mairani (now INFN), F. Sommerer (Uniklinikum Heidelberg), I. Rinaldi (DKFZ Heidelberg), K. Parodi (HIT and University of Heidelberg)
Workshop on Hadron Beam Therapy of Cancer Erice, Sicily April 24-May
IONTRIS Synchrotron based PT Solutions from Siemens AG Workshop on Hadron Beam Therapy of Cancer Erice, Sicily April 24-May 1 2009 Matthias Herforth VP Business Development and Communications Siemens AG
Firing Protons at Lesions
Visionaries 2014 Firing Protons at Lesions Molecular Tracking Proton Beam Therapy System at Hokkaido University Radiotherapy is widely used as a treatment for cancer (malignant tumors) that has minimal
8/1/2016. Motion Management for Proton Lung SBRT. Outline. Protons and motion. Protons and Motion. Proton lung SBRT Future directions
Motion Management for Proton Lung SBRT AAPM 2016 Outline Protons and Motion Dosimetric effects Remedies and mitigation techniques Proton lung SBRT Future directions Protons and motion Dosimetric perturbation
Present Status and Future Developments in Proton Therapy
Present Status and Future Developments in Proton Therapy Alfred R. Smith Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030,
Intensity Modulated RadioTherapy
Intensity Modulated RadioTherapy A clinical application of a small accelerator University Medical Center Groningen A.A. van t Veld PhD I. Hoveijn PhD part 1 part2 CERN/KVI accelerator school, Zeegse, June
Radiological Protection in Ion Beam Radiotherapy
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 ICRP ref 4851-1931-9834 17 April 2014 Annals of the ICRP ICRP PUBLICATION 1XX Radiological Protection in Ion Beam Radiotherapy 16 17 18 19 20 21 22 23 24 25 26 27 28
Treatment Planning (Protons vs. Photons)
Treatment Planning Treatment Planning (Protons vs. Photons) Acquisition of imaging data Delineation of regions of interest Selection of beam directions Dose calculation Optimization of the plan Hounsfield
Proton and helium beams: the present and the future of light ion beam therapy
Proton and helium beams: the present and the future of light ion beam therapy Dr. Andrea Mairani Group Leader Biophysics in Particle Therapy Heidelberg Ion Beam Therapy Center HIT Department of Radiation
Practical Challenges and Opportunities for Proton Beam Therapy. M. F. Moyers Loma Linda University Medical Center
Practical Challenges and Opportunities for Proton Beam Therapy M. F. Moyers Loma Linda University Medical Center Outline I. Introduction II. Registration and Immobilization III. Beam Shaping IV. Localization
S. Derreumaux (IRSN) Accidents in radiation therapy in France: causes, consequences and lessons learned
S. Derreumaux (IRSN) Accidents in radiation therapy in France: causes, consequences and lessons learned MEDICAL LINEAR ACCELERATORS Electron beam (MeV) Photon beam (MV) PRECISION REQUIRED IN RADIOTHERAPY
ACCELERATOR DESIGN ISSUES IN CANCER THERAPY
ACCELERATOR DESIGN ISSUES IN CANCER THERAPY December 25 P.J. Bryant CERN John ADAMS Memorial Lecture 25- P.J. Bryant - Slide 1 Contents Introduction Hadrons & voxel scanning Experimental setup A closer
Image Guided Proton Therapy and Treatment Adaptation
Image Guided Proton Therapy and Treatment Adaptation www.hollandptc.nl d.r.schaart@tudelft.nl Cancer in The Netherlands About 1 in 3 people get cancer in some stage of their life 86.800 new cancer patients
Road Map for the development of hadron therapy and associated nuclear medicine methods at JINR:
НТС ОЭЗ, 07 октября 2011 Road Map for the development of hadron therapy and associated nuclear medicine methods at JINR: Development of 3D conformal Proton therapy Design of various devices for proton
Hampton University Proton Therapy Institute
Hampton University Proton Therapy Institute Brief introduction to proton therapy technology, its advances and Hampton University Proton Therapy Institute Vahagn Nazaryan, Ph.D. Executive Director, HUPTI
Summary of Synchrotron for Hadron Therapy
Summary of Synchrotron for Hadron Therapy April 30, 09 Koji Noda 1. G.H. Rees ; A New Tracking Gantry-Synchrotron Idea 2. K. Noda ; Overview of NIRS Accelerator Activity 3. T. Haberer ; The Heidelberg
Radiotherapy. Marta Anguiano Millán. Departamento de Física Atómica, Molecular y Nuclear Facultad de Ciencias. Universidad de Granada
Departamento de Física Atómica, Molecular y Nuclear Facultad de Ciencias. Universidad de Granada Overview Introduction Overview Introduction Brachytherapy Radioisotopes in contact with the tumor Overview
Scoring of linear energy transfer (LET) for calculation of biological dose in proton therapy
Scoring of linear energy transfer (LET) for calculation of biological dose in proton therapy And why biological calculation should be done within FLUKA Eivind Rørvik May 11, 216 Eivind Rørvik 4th Fluka
Application of Implanted Markers in Proton Therapy. Course Outline. McLaren Proton Therapy Center Karmanos Cancer Institute McLaren - Flint
Application of Implanted Markers in Proton Therapy Sung Yong Park, Ph.D. McLaren Proton Therapy Center Karmanos Cancer Institute McLaren - Flint AAPM 2016, SAM Therapy Educational Course, 2016.08.04. Course
Particle Radiation Therapy. Sophi Farid Phys 3305 Southern Methodist University Spring 2016
1 Particle Radiation Therapy Sophi Farid Phys 3305 Southern Methodist University Spring 2016 2 Outline I. What is Cancer II. Typical Cancer treatment III. How is particle radiation different IV. Particle-Tissue
Dr. Robert R. Wilson, a physicist who had worked on
Radiation Therapy With Charged Particles Daniela Schulz-Ertner, MD,* Oliver Jäkel, PhD, and Wolfgang Schlegel, PhD Charged particle beams can offer an improved dose conformation to the target volume as
PAMELA Particle Accelerator for MEdicaL Applications
PAMELA Particle Accelerator for MEdicaL Applications Suzie Sheehy, DPhil candidate John Adams Institute for Accelerator Science Particle Physics, University of Oxford 1 Clinical Requirements Charged Particle
Research on Cancer Therapy with Carbon Beams Development of Human-Friendly Cancer Therapy with Carbon Ion Beams
Research on Cancer Therapy with Carbon Beams Development of Human-Friendly Cancer Therapy with Carbon Ion Beams Tadashi Kamada, M.D., Ph.D. Director of Research Center for Charged Particle Therapy E-mail:
Clinical effectiveness of fractionated treatments with C ions relative to photons - accounting for hypoxia dynamics
Clinical effectiveness of fractionated treatments with C ions relative to photons - accounting for hypoxia dynamics AUTHORS Dr Laura Antonovic, Stockholm University, Sweden Dr Alexandru Dasu, Linköping
Proton Beam Therapy at Mayo Clinic
Proton Beam Therapy at Mayo Clinic Jon J. Kruse, Ph.D. Mayo Clinic Dept. of Radiation Oncology Rochester, MN History of Proton Therapy at Mayo 2002: Decided to consider particle therapy analysis and education
Status of Hadrontherapy facilities worldwide
Status of Hadrontherapy facilities worldwide Vienna 15.03.2011 The Gantry 1 of PSI Eros Pedroni Center for Proton Radiation Therapy Paul Scherrer Institute SWITZERLAND Author s competence: Gantry with
Multi-Ion Analysis of RBE using the Microdosimetric Kinetic Model
Multi-Ion Analysis of RBE using the Microdosimetric Kinetic Model Council of Ionizing Radiation Measurements and Standards (CIRMS) March 28 th, 2017 Michael P. Butkus 1,2 Todd S. Palmer 2 1 Yale School
Beam Loss and Collimation in the ESS Linac
Beam Loss and Collimation in the ESS Linac Ryoichi Miyamoto (ESS) B. Cheymol, H. Danared, M. Eshraqi, A. Ponton, J. Stovall, L. Tchelidze (ESS) I. Bustinduy (ESS-Bilbao) H. D. Thomsen, A. I. S. Holm, S.
DPA calculations with FLUKA
DPA calculations with FLUKA A. Lechner, L. Esposito, P. Garcia Ortega, F. Cerutti, A. Ferrari, E. Skordis on behalf of the FLUKA team (CERN) with valuable input from R. Bruce, P.D. Hermes, S. Redaelli
Overview of Clinical and Research Activities at Georgetown University Hospital
Overview of Clinical and Research Activities at Georgetown University Hospital Dalong Pang, Ph.D. Department of Radiation Medicine Georgetown University Hospital Clinical Operation Two Varian linear accelerators
IN VIVO IMAGING Proton Beam Range Verification With PET/CT
IN VIVO IMAGING Proton Beam Range Verification With PET/CT Antje-Christin Knopf 1/3 K Parodi 2, H Paganetti 1, T Bortfeld 1 Siemens Medical Solutions Supports This Project 1 Department of Radiation Oncology,
Nuclear Physics in Proton Radiotherapy
Nuclear Physics in Proton Radiotherapy Cynthia Keppel, PhD Thomas Jefferson National Accelerator Facility (Hampton University Proton Therapy institute) International Nuclear Physics Conference Adelaide,
Changing Paradigms in Radiotherapy
Changing Paradigms in Radiotherapy Marco van Vulpen, MD, PhD Mouldroomdag-2015 Towards the elimination of invasion 1 NIH opinion on the future of oncology Twenty-five years from now,i hope that we won
I. Equipments for external beam radiotherapy
I. Equipments for external beam radiotherapy 5 linear accelerators (LINACs): Varian TrueBeam 6, 10 & 18 MV photons, 6-18 MeV electrons, image-guided (IGRT) and intensity modulated radiotherapy (IMRT),
Introduction. Measurement of Secondary Radiation for Electron and Proton Accelerators. Introduction - Photons. Introduction - Neutrons.
Measurement of Secondary Radiation for Electron and Proton Accelerators D. Followill, Ph.D. Radiological Physics Center U. T. M. D. Anderson Cancer Center Introduction Patients undergoing radiation therapy
Recent advances in dosimetry in reference conditions for proton and light-ion beams
Recent advances in dosimetry in reference conditions for proton and light-ion beams S. Vatnitskiy a), P. Andreo b) and D.T.L. Jones c) a) MedAustron, Wiener Neustadt, Austria b) Medical Radiation Physics,
Status of Proton Therapy: results and future trends
Status of Proton Therapy: results and future trends E. Pedroni Paul Scherrer Institute Division of Radiation Medicine CH-5232 Villigen PSI Abstract The number of centres investigating proton therapy in
A Facility for Tumour Hadron Therapy and Biomedical Research in South-Eastern Europe
SEEIIST South East Europe International Institute for Sustainable Technologies A Facility for Tumour Hadron Therapy and Biomedical Research in South-Eastern Europe U. Amaldi a, J. Balosso b, M. Dosanjh
Dosimetric characterization with 62 MeV protons of a silicon segmented detector for 2D dose verifications in radiotherapy
Dosimetric characterization with 62 MeV protons of a silicon segmented detector for 2D dose verifications in radiotherapy C. Talamonti a*, M. Bucciolini a, L. Marrazzo a, D. Menichelli a. a) Department
Advances in external beam radiotherapy
International Conference on Modern Radiotherapy: Advances and Challenges in Radiation Protection of Patients Advances in external beam radiotherapy New techniques, new benefits and new risks Michael Brada
Protons Monte Carlo water-equivalence study of two PRESAGE formulations for proton beam dosimetry J. Phys.: Conf. Ser.
Protons Monte Carlo water-equivalence study of two PRESAGE formulations for proton beam dosimetry T Gorjiara, Z Kuncic, J Adamovics and C Baldock 2013 J. Phys.: Conf. Ser. 444 012090 PRESAGE is a radiochromic
Clinical Concept and History of Protons. Relevance and Limitations of Conformality. Gudrun Goitein
Clinical Concept and History of Protons Relevance and Limitations of Conformality Gudrun Goitein PSI Winter School January 2010 Bad Zurzach and PSI, Villigen Switzerland P + Who came first: The Clinical
Radiation Treatment Techniques: Where to find rooms for improvement?
Radiation Treatment Techniques: Where to find rooms for improvement? Cedric Yu, D.Sc. Carl M. Mansfield, M.D. Professor University of Maryland School of Medicine Founder and CEO, Xcision Medical Systems,
Aspects of Industrialization of Accelerators for Particle Therapy ICABU, November 11, 2013, Daejeon
Aspects of Industrialization of Accelerators for Particle Therapy ICABU, November 11, 2013, Daejeon Introduction Why Particle Therapy? PT Milestones What is meant by Industrialization Examples Protons-only:
Considerations when treating lung cancer with passive scatter or active scanning proton therapy
Mini-Review Considerations when treating lung cancer with passive scatter or active scanning proton therapy Sara St. James, Clemens Grassberger, Hsiao-Ming Lu Department of Radiation Oncology, Massachusetts