Current Position: Senior Lecturer, Department of Human Pathology, School of medicine, CHS, UON, and

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1 Name: Dr. Lucy Wangari Muchiri, MBCHB, MMed(Path), PGBRM, PhD Current Position: Senior Lecturer, Department of Human Pathology, School of medicine, CHS, UON, and Consultant Pathologist, Kenyatta National Hospital Work experience Intern, Ministry of Health, Kenyatta National Hospital Pathology Resident, Ministry of Health, Kenyatta National Hospital Lecturer, Consultant Pathologist, Dept of Human Pathology, University of Nairobi/Kenyatta National Hospital 2003 to date Senior Lecturer, Consultant Pathologist, Dept. of Human Pathology/Kenyatta National Hospital Chairman, Dept of Human Pathology, University of Nairobi 2004 to 2010 Sessional Consultant Pathologist, The Nairobi Hospital 2005 to date Sessional Consultant Pathologist & Chief of Pathology, The Mater Hospital Consultant Pathologist, Pathologists Lancet Kenya, November 2010 to date. Education MBCHB, University of Nairobi MMed Pathology, , University of Nairobi Post-graduate Diploma in Biomedical Research Methodology,

2 PhD 2004-to 2010, University of Nairobi, completed thesis: HIV and Cervical Cancer in a Kenyan semi-urban population. Awarded Dec 3rd Fellowships Cytopathology, (12 months), Health Sciences Centre, University of Manitoba, Winnipeg, Canada Health & Behaviour Research, (10months), Dept. of Social Sciences, Harvard Medical School, Harvard University, Boston, USA Short Courses Cancer Management and Prevention/Molecular Biology of Cancer, Summer 2005, NIH, Bethesda, Maryland, USA Stata Course, University of Nairobi/Danish Institute of Tropical Medicine August 2006 Courses in Bioethics A WHO training on Research in Microbicides, Gabarone, Botswana, 2004 An NIH training in research on Human Subjects, Kampala, Uganda, 2005 A joint training workshop by KNH/UON-ERC and University of Washington, Seattle, SilverSprings, Nairobi, Kenya, 2008 A training workshop on Research & ethics in Malaria, Zanzibar, 2003 Professional memberships Kenya Association of Clinical Pathologists (KACP) Kenya Society of Haematology and Oncology (KESHO) Kenya Medical Women s Association (KMWA) Kenya Medical Association East Africa Division of International Academy of Pathology (EA-IAP) Association of Pathologists of East Central & Southern Africa (APECSA) AORTIC COPECSA Founder member PAC Chair, Executive Council

3 Publications: 1. The impact of human immunodeficiency virus and human papilloma virus coinfection on HPV genotype distribution and cervical lesion grade in a semi-urban population in Tigoni, Kenya. Muchiri LW, Kigondu CBS., Ndirangu G, Gichangi P, Machoki J.M, Estambale BBA, Temmerman M. Afri. J. Pharmacol. Ther. (In Press) 2. Risk Association between Human Leucocyte Antigen (HLA) and cervical neoplasia in Kenyan women. Muchiri LW, Kigondu CBS, Estambale BBA, Temmerman M. Afr. J. Pharmacol. Ther (1): Fine needle aspiration cytology of thyroid nodules at Kenyatta National Hospital, Nairobi. Sang CK, Sekadde-Kigondu C, Muchiri L.East Afr Med J Mar;84(3): PMID: [PubMed - indexed for MEDLINE] 4..Correlation between cytology and thyroid function test. Sang CK, Kigondu CS, Muchiri L. East Afr Med J Oct;83(10): PMID: [PubMed - indexed for MEDLINE] 5. Progesterone, estradiol and their receptors in leiomyomata and the adjacent normal myometria of black Kenyan women. Wango EO, Tabifor HN, Muchiri LW, Sekadde- Kigondu C, Makawiti DW. Afr J Health Sci Jul-Dec;9(3-4): PMID: [PubMed - indexed for MEDLINE] 6. The effects of HIV-1 Tat protein on cell cycle during cervical carcinogenesis. Nyagol J, Leucci E, Onnis A, De Falco G, Tigli C, Sanseverino F, Torriccelli M, Palummo N, Pacenti L, Santopietro R, Spina D, Gichangi P, Muchiri L, Lazzi S, Petraglia F, Leoncini L, Giordano A. Cancer Biol Ther Jun;5(6): Epub 2006 Jun 18. PMID: [PubMed - indexed for MEDLINE] 7. Routine assessment of hormonal receptor and her-2/neu status underscores the need for more therapeutic targets in Kenyan women with breast cancer. Nyagol J, Nyong'o A, Byakika B, Muchiri L, Cocco M, de Santi MM, Spina D, Bellan C, Lazzi S, Kostopoulos I, Luzi P, Leoncini L. Anal Quant Cytol Histol Apr;28(2): Comparison of pap smear, visual inspection with acetic acid, human papillomavirus DNA-PCR testing and cervicography. De Vuyst H, Claeys P, Njiru S, Muchiri L, Steyaert S, De Sutter P, Van Marck E, Bwayo J, Temmerman M. Int J Gynaecol Obstet May;89(2): PMID: [PubMed - indexed for MEDLINE] 9. Laboratory diagnosis of Hodgkin's disease: what are the challenges? Muchiri L. East Afr Med J Mar;80(3): PMID: [PubMed - indexed for MEDLINE] 10. Distribution of human papillomavirus in a family planning population in nairobi, kenya. De Vuyst H, Steyaert S, Van Renterghem L, Claeys P, Muchiri L, Sitati S, Vansteelandt S, Quint W, Kleter B, Van Marck E, Temmerman M. Sex Transm Dis Feb;30(2): PMID: [PubMed - indexed for MEDLINE] 11. Role of fine needle aspiration in the diagnosis of neoplasms. Muchiri LW. East Afr Med J May;78(5):225. PMID: [PubMed - indexed for MEDLINE] 12. Risk factors for human papillomavirus and cervical precancerous lesions, and the role of concurrent HIV-1 infection. Temmerman M, Tyndall MW, Kidula N, Claeys P, Muchiri L, Quint W. Int J Gynaecol Obstet May;65(2): PMID: [PubMed - indexed for MEDLINE] 13. The supermarket for women's reproductive health: the burden of genital infections in a family planning clinic in Nairobi, Kenya. Temmerman M, Kidula N, Tyndall M, Rukaria-

4 Kaumbutho R, Muchiri L, Ndinya-Achola JO. Sex Transm Infect Jun;74(3): PMID: [PubMed - indexed for MEDLINE] 14. Quantitative assessment of oestrogen and progesterone receptors on fine-needle aspirates and cryostat sections of breast carcinomas: how does this compare with biochemical assays? Muchiri LW. East Afr Med J May;70(5): PMID: [PubMed - indexed for MEDLINE] 15. Role of fine-needle aspiration biopsy in the diagnosis of breast lumps at the Kenyatta National Hospital. Muchiri LW, Penner DW, Adwok J, Rana FS. East Afr Med J Apr;70(4 Suppl):31-3. PMID: [PubMed - indexed for MEDLINE] Presentations: The impact of HIV infection on cervical neoplasia in a Kenyan Semi-urban population. September 16th, 2006 The Centennial IAP Congress. Montreal, Canada The Utility of a rapid test for syphilis in an ART clinic in Tigoni at the Annual Scientific meeting of Sexually Transmitted Infections and HIV/AIDS, January 2008, Nairobi The Breast Cancer Awareness month: The Mater Hospital Experience at the 9th APECSA Conference, Mombasa, October, 2008 Muchiri L, Rajab J, Luseno G. Medical Students and the Autopsy: A survey of medical students in a Nairobi Medical School, at the 9th APECSA Conference, Mombasa, October, Kalebi A, Muchiri L, Gachie R, Gatei D. HIV infection and cervical neoplasia in a Kenyan semi-urban population. Lucy Muchiri, Gathari Ndirangu, Christine Kigondu, Peter Gichangi, James Machoki, Benson Estambale, Marleen Temmerman, at 9th APECSA Conference, Mombasa, October, PANELIST & GUEST SPEAKER Gardasil Vaccine Launch MSD July 26th, 2008, Grand Regency Hotel, Nairobi Cervarix Vaccine Launch GSK August 8th, 2009, Hotel Intercontinental, Nairobi Gardasil Vaccine Launch MSD April 27th, 2009, Intercontinental Hotel, Addis Ababa, Ethiopia. Qiagen HPV test Kit launch Bio-Zeq Kenya May 22nd, 2009 Role of HPV in Cancer, The Nairobi Hospital Annual Scientific Conference, 6th June, 2010, Nairobi, Kenya Molecular Screening for Cervical Cancer, 15th July 2010

5 Cervical cancer prevention in Africa, INTEREST Scientific workshop, Mombasa, Kenya May 8 th to 11 th, 2012 Cervical cancer Prevention, African Cancer Foundation 1 st Anniversary, July 15 th, Lymphomas What can we learn from Africa? (3 rd Edition) January 31 st to Feb 2 nd 2013 National Guidelines in Cancer management, January, 2013, Naivasha, Kenya Postgraduate training in Pathology, One day workshop. November 23 rd, 2012 at AKU, Nairobi. Awards and Scholarships received 1989 Ministry of Health full scholarship for MMed Pathology 1990 CIDA/University of Nairobi Fellowship in Cytopathology at the University of Manitoba 1993 Carnegie Fellowship in Health & Behaviour Research at Harvard University (10 months) 1999 Carnegie Fellowship in Health & Behaviour research at Harvard University (3 months) 2005 NIH Fellowship in Cancer Management & Prevention at NIH, Bethesda, MD, USA (2months) Stata Course (UNITID/Danish Institute of tropical Medicine) at University of Nairobi (2 weeks) PG Diploma in Biomedical Research Methodology partial scholarship at the University of Nairobi PhD VLIR/University of Nairobi Scholarship at the University of Nairobi Grants Canadian Association of Pathology (CAP) Humanitarian Grant 2007 (USD 30,000) GSK/Wells Healthcare Research Grant 2008 (USD 10,000) CARTA-Med Grant for research on The Appropriateness of Selected Health System analysis interventions to improve the performance of clinical officers in Kenya, Uganda and South Africa: A multi-country study 2009 (local grant USD 22,000).

6 External Examiner: Moi Teaching and referral Hospital Muhimbili University College of Health Sciences Aga Khan University 2012/2013

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