Yours faithfully, Professor Hilda Marima-Matarira. President ZACB and Laboratory Medicine. Zimbabwe Representative on AFCC and IFCC

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1 Dear All, You are warmly invited to the 16 th Zimbabwe Association of Clinical Biochemists and Laboratory Medicine s National Course on Molecular Diagnostics Hands On to be held in collaboration with the University of Zimbabwe College of Health Sciences and the National Biotechnology Authority of Zimbabwe. The course will be held on 20 th -22 nd August 2018 at National Biotechnology Laboratories at 21 Princess Drive in Newlands, Harare, Zimbabwe. Molecular diagnostics techniques are used to analyse biological markers in the genome and proteome in diagnosis, and monitoring of diseases, decide therapies/drugs that work best for individual patients in predictive, preventative and personalized laboratory medicine and detect risk. Molecular diagnostic tests are mostly used in oncology, infectious diseases such as HIV, drug resistant diseases, neurosciences, cardiology and metabolic disorders. The techniques are used to identify, map and sequence genes in basic biomedical researches, to determine their functions in human and veterinary medicine, GMO foods and large scale pharmaceutical products eg Insulin and HBV vaccine etc. In agriculture, the uses extend to production of herbicide and insect resistant crops. In industry the uses are many e.g. in bio-engineering of for example fuel.

2 Recent development in molecular diagnostic tests i.e. Point of Care Tests with high specificity and sensitivity is most welcome. Evidence is available that shows these tests now assist in improving turn-around time of results, reduce mortalities and complications of diseases, are effective in screening cancer, HIV and drug resistant infections. In some instances, molecular diagnostic tests significantly save on medical costs by facilitating treatment interventions thus improving patients outcomes, adherence and compliance, improving prediction of treatment and also improving prognosis in type 2 DM, breast cancer, colorectal cancer, small cell lung cancer, thrombophilia, obesity, haemochromatosis and smoking cessation etc. Students, postgraduates, various biomedical researchers, clinicians and experts in disciplines of Pathology, biotechnology, human and veterinary medicine would benefit greatly from this practical Hands On course. You are indeed most welcome to participate. This unique experience will enable you to share new knowledge, network meet and make new and renew friendships in an awakening Harare city known to many as the Sunshine City. Yours faithfully, Professor Hilda Marima-Matarira President ZACB and Laboratory Medicine Zimbabwe Representative on AFCC and IFCC FOR REGISTRATION chemicalpathology777@gmail.com chempath@medsch.uz.ac.zw TELEPHONE: Ext 2126 CELL PHONES: Cathy: Olive: COURSE FEES:$ VENUE : SEE GOOGLE MAP ATTACHED.

3 16 th ANNUAL ZACB ANNUAL COURSE IN MOLECULAR DIAGNOSTICS HANDS ON : 20 th -22 nd AUGUST 2018 :NBA: 21 PRINCESS DRIVE NEWLANDS HARARE (ZIMBABWE) 20 TH AUGUST Registration OM Gudza Secretariat Welcome Hilda Marima- Matarira & Jonathan Mufandaedza Plenary Lecture Molecular Diagnostics in Nutritional Disorders Lucy Mabaya Welcome and Introduction to the Practicals Cuthbert Musarurwa Tea Break DNA Extraction and electrophoresis (short lecture) Kudakwashe Mhandire/P Munjoma/T Mudhlulu/D Chiveto DNA extraction and Preparation of Agarose Gels Lunch Polymerase chain reaction lecture (short lecture)

4 Kudakwashe Mhandire/P Munjoma/T Mudhlulu/D Chiveto PCR practical End of Day 1 21 st AUGUST Plenary Lecture Emerging Markers in Cardiovascular Diseases Alfred Gomo Restriction fragment length polymorphism [RFLP] (lecture and practical) Kudakwashe Mhandire/P Munjoma/T Mudhlulu/D Chiveto Tea Break GC- Mass Spectrometry Assays in Laboratory Medicine Raylton Chikwati RFLP (Gel electrophoresis) Lunch RFLP (Result interpretation) Kudakwashe Mhandire/P Munjoma/T Mudhlulu/D Chiveto Close of day 22 nd AUGUST Plenary Lecture Recent Advances in Molecular Diagnostics in Cancer. Hilda Matarira Molecular Diagnostics in Infectious Diseases in Early Infant Diagnosis Justin Manase National Biotechnology Services In Zimbabwe Jonathan Mufandaedza

5 YS-ZACB-AFCC-IFCC Networking. Itai Chitungo Tea Break and Close Witmore Mujaji