Development of a predictive model for vaccine matching for serotype O FMDV from serology and capsid sequence

FMD Vaccine Strain Selection

FMD Vaccine Strain Selection David Paton, Pirbright, UK New Delhi, 13-15 February 2012 Conclusions Vaccine match is one component of vaccine efficacy Vaccine quality may compensate for imperfect match

Richard Reeve Boyd Orr Centre for Population and Ecosystem Health University of Glasgow

Advances and gaps in vaccine modelling Richard Reeve Boyd Orr Centre for Population and Ecosystem Health University of Glasgow 1 Should I vaccinate? In disease-free countries, the decision may be difficult

FMD Carrier state and role of carrier buffalo as source of transboundary spread in Southeast Asia and Eastern Asia Satya Parida

FMD Carrier state and role of carrier buffalo as source of transboundary spread in Southeast Asia and Eastern Asia Satya Parida, Pirbright, UK Foot-and-mouth disease Highly contagious disease of all the

Predicting antigenic sites on the FMDV. F.F. Maree, R. Reeve, B. Blignaut, J.J. Esterhuysen, E. Fry, T. de Beer, E. Rieder and D.

Predicting antigenic sites on the FMDV capsid from cross-reactivity reactivity data F.F. Maree, R. Reeve, B. Blignaut, J.J. Esterhuysen, E. Fry, T. de Beer, E. Rieder and D.Haydon Introduction The SAT

Pirbright and ISZLER. EuFMD Open Session 2018

A universal test to quantitate protective antigen during production of foot-and-mouth disease vaccines Amin Asfor, Nathalie Howe, Santina Grazioli, Emiliano Brocchi and Toby Tuthill Pirbright and ISZLER

FAO Collaborative Study Phase XVII: Standardisation of FMD Antibody Detection

Appendix 28 FAO Collaborative Study Phase XVII: Standardisation of FMD Antibody Detection D J Paton, R M Armstrong, L S Turner, P A Hamblin, M Corteyn, D Gibson, J Anderson Institute for Animal Health,

FMD diagnostics: current developments and application in the context of FMD control in endemic countries Wilna Vosloo

FMD diagnostics: current developments and application in the context of FMD control in endemic countries Wilna Vosloo CSIRO Livestock Industries, Australian Animal Health Laboratory (AAHL), Geelong, Australia

Field study conducted in Tunisia to evaluate efficacy of an O-BFS vaccine

Field study conducted in Tunisia to evaluate efficacy of an O-BFS vaccine FAO/OIE Reference Lab for FMD Emiliana Brocchi Institut de la Recherche Vétérinaire de Tunisie - Service Virologie Soufien Sghaier

Engineering Foot-and-Mouth Disease Virus with Improved Properties for the Development of Effective Vaccine Introduction: Materials and methods:

Engineering Foot-and-Mouth Disease Virus with Improved Properties for the Development of Effective Vaccine Haixue Zheng, Fan Yang, Ye Jin, Jianhong Guo, Jijun He, Kaiqi Lian, Zixiang Zhu, Weijun Cao, Lvlv,

Fufa Dawo Bari, 1 Satya Parida, 1 Amin S. Asfor, 1 Daniel T. Haydon, 2 Richard Reeve, 1,2 David J. Paton 1 and Mana Mahapatra 1 INTRODUCTION

Journal of General Virology (2015), 96, 1033 1041 DOI 10.1099/vir.0.000051 Prediction and characterization of novel epitopes of serotype A foot-and-mouth disease viruses circulating in East Africa using

The work of the WRLFMD in relation to regional networks. Reference Laboratory for FMDV

The work of the WRLFMD in relation to regional networks Reference Laboratory for FMDV WRLFMD - GOODBYE TO: Nigel Ferris January 2012 Geoff Hutchings July 2012 Claudia Doel March 2013 Miki Madi June 2013

1. Engineering Foot-and-Mouth Disease Viruses with Improved

Engineering Foot-and-Mouth Disease Virus with Improved Properties for the Development of Effective Vaccine Haixue Zheng, Fan Yang, Ye Jin, Jianhong Guo, Jijun He, Lvlv, Xuepeng Cai, Xiangtao Liu, Hong

Longevity of protection in cattle following vaccination with emergency FMD vaccines from the UK strategic reserve

Longevity of protection in cattle following vaccination with emergency FMD vaccines from the UK strategic reserve Sarah Cox, Satya Parida, Pip Hamblin, Bartek Bankowski Veronica Carr, David Paton and Paul

Sequence-Based Prediction for Vaccine Strain Selection and Identification of Antigenic Variability in Foot-and- Mouth Disease Virus

Sequence-Based Prediction for Vaccine Strain Selection and Identification of Antigenic Variability in Foot-and- Mouth Disease Virus Richard Reeve 1,2 *, Belinda Blignaut 3,4, Jan J. Esterhuysen 3, Pamela

The early pathogenesis of FMD and the implications for control measures

The early pathogenesis of FMD and the implications for control measures Luis L. Rodriguez and Jonathan Arzt Foreign Animal Disease Research Unit, USDA-ARS Plum Island Animal Disease Center, New York, USA.

OIE RRL-Lanzhou Activities, Research and Lab network

Expanded 3 rd National Coordinators Meeting OIE/JTF project on FMD Control in east Asia, Sep 23-26 2014 Lanzhou, China OIE RRL-Lanzhou Activities, Research and Lab network Dr. Hong YIN OIE FMD Reference

Foot-and-mouth disease virus persistence and evolution. Bryan Charleston, Pirbright Institute

Foot-and-mouth disease virus persistence and evolution Bryan Charleston, Pirbright Institute FMD: a priority impediment to wellbeing Animal health and welfare impacts on human health Conjectured Status

FMD in Southern Africa

Molecular Biological Characteristics of Foot-and- Mouth Disease Virus in the African Buffaloes in Southern Africa Christopher Kasanga 1, Rahana Dwarka 2, Gaothlele Thobokwe 3, Jemma Wadsworth 4, Nick Knowles

FMD VACCINE AND VACCINATION. Ahmad Al-Majali Dean, Faculty of Vet Medicine JUST Jordan

FMD VACCINE AND VACCINATION Ahmad Al-Majali Dean, Faculty of Vet Medicine JUST Jordan General Considerations on FMD vaccination The currently used FMD vaccines are killed virus preparations that are pure,

Mutants and HBV vaccination. Dr. Ulus Salih Akarca Ege University, Izmir, Turkey

Mutants and HBV vaccination Dr. Ulus Salih Akarca Ege University, Izmir, Turkey Geographic Distribution of Chronic HBV Infection 400 million people are carrier of HBV Leading cause of cirrhosis and HCC

Vaccines and viral antigenic diversity

Rev. sci. tech. Off. int. Epiz., 2007, 26 (1), 69-90 Vaccines and viral antigenic diversity J.A. Mumford Cambridge Infectious Diseases Consortium, Department of Veterinary Medicine, University of Cambridge,

FMD in Libya. Dr. Abdunaser Dayhum National Center of Animal Health Libya

FMD in Libya Dr. Abdunaser Dayhum National Center of Animal Health Libya Foot-and-Mouth Disease Cause: Foot-and-mouth disease virus (FMDV). A total of seven different serologic types are recognized: A,

High potency vaccines induce protection against heterologous challenge with FMD virus

High potency vaccines induce protection against heterologous challenge with FMD virus Katharina Brehm, Naveen Kumar, Hans-Herman Thulke and Bernd Haas Principle of current production method for FMD vaccines

Appendix 30. Preliminary results to evaluate cross-protection between O 1 Manisa and O 1 Campos in cattle

Appendix 30 Preliminary results to evaluate cross-protection between O 1 Manisa and O 1 Campos in cattle V.A. Srinivasan 1, S.B.Nagendra Kumar 1, M.Madhan Mohan 1, V.Maroudam 1, P.Santha Kumar 1, S. Parida

WEST EURASIA FMD LAB PHASE ACTIVITY PROPOSAL. A. Naci BULUT Head of the Diagnosis Department, Şap Institute

WEST EURASIA FMD LAB NETWORK WELNET FMD- 2ND PHASE ACTIVITY PROPOSAL FAO/the EuFMD Commission, 39th General Session, 27/28 April 2011 Rome, Italy A. Naci BULUT Head of the Diagnosis Department, Şap Institute

Foot and Mouth Disease Vaccine Research and Development in India

Foot and Mouth Disease Vaccine Research and Development in India R.Venkataramanan Indian Veterinary Research Institute, Hebbal, Bangalore 560 024 Foot and Mouth Disease in India Present Status Large Susceptible

O 38% NVD 42% A 10% Asia 1 9% SAT2 1% SAT1 <1% Institute for Animal Health

Serotypes Identified 2011 NVD 42% 38% Asia 1 9% A 10% Institute for Animal Health 1% SAT1 600 positive >900 Samples from 23 Countries 23 countries ~900 samples Bulgaria Turkey, A

BIOCHEMISTRY REVIEW. Overview of Biomolecules. Chapter 4 Protein Sequence

BIOCHEMISTRY REVIEW Overview of Biomolecules Chapter 4 Protein Sequence 2 3 4 Are You Getting It?? A molecule of hemoglobin is compared with a molecule of lysozyme. Which characteristics do they share?

A solid-phase competition ELISA for measuring antibody to foot-and-mouth disease virus

197 Appendix 24 A solid-phase competition ELISA for measuring antibody to foot-and-mouth disease virus N.P. Ferris a, A.N. Bulut b, T. Rendle a, F. Davidson a and D.K.J. Mackay c a b c Institute for Animal

Vaccine Matching and Development of Appropriate Vaccines

Vaccine Matching and Development of Appropriate Vaccines Dr Gaolathe Thobokwe SSARRL @Botswana Vaccine InsBtute Reference Laboratories and Collabora-ng Centres Addi-onal Reference Centres Regional/Na-onal

Appendix 72 Using NSP ELISA (Chekit-FMD-3ABC Bommeli-Intervet) as a Tool for FMDV Serosurveillance in Bulgaria Abstract: Introduction

Appendix 72 Using NSP ELISA (Chekit-FMD-3ABC Bommeli-Intervet) as a Tool for FMDV Serosurveillance in Bulgaria Georgi Georgiev*¹, Emiliya Veleva¹, Liliyana Polihronova¹ and Alessandro Rossi² 1 National

Introduction to Avian Influenza

Introduction to Avian Influenza David L. Suarez D.V.M., Ph.D. Research Leader Exotic and Emerging Avian Viral Disease Research Unit Agricultural Research Service United States Department of Agriculture

Preparing for the unexpected: the response to foot-and-mouth disease outbreaks in 2007 in the United Kingdom

Preparing for the unexpected: the response to foot-and-mouth disease outbreaks in 2007 in the United Kingdom Donald King donald.king@pirbright.ac.uk Vesicular Disease Reference Laboratory Group FMD and

OIE Reference Laboratory Reports Activities

OIE Reference Laboratory Reports Activities Activities in 2014 This report has been submitted : 2015-01-16 15:04:37 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Equine

Mandate and Activities of an OIE Reference Laboratory

Mandate and Activities of an OIE Reference Laboratory Nairobi Training 9-11 August 2011 Dr G Thobokwe BVI (OIE Sub Saharan Regional Reference Laboratory for FMD Diagnosis) gthobokwe@bvi.co.bw ABOUT BVI

Foot and Mouth Disease Middle East situation Summary of Answers to the Questionnaire Beirut, Lebanon, 7 9 April 2009

Foot and Mouth Disease Middle East situation Summary of Answers to the Questionnaire Beirut, Lebanon, 7 9 April 2009 Dr Pierre Primot OIE for the Middle East Purpose of the Questionnaire The purpose of

Overview of WRL FMD. Historical perspective. Principal activities. FMD threats. Needs/prospects. David Paton

Tracking the emergence and global spread of foot-and-mouth disease (FMD) Overview of WRL FMD David Paton Historical perspective Principal activities FMD threats Needs/prospects Historical Perspective FMD

Supplementary Figure-1. SDS PAGE analysis of purified designed carbonic anhydrase enzymes. M1-M4 shown in lanes 1-4, respectively, with molecular

Supplementary Figure-1. SDS PAGE analysis of purified designed carbonic anhydrase enzymes. M1-M4 shown in lanes 1-4, respectively, with molecular weight markers (M). Supplementary Figure-2. Overlay of

The global control of FMD; challenges and opportunities

EuFMD-Erice 2008 The global control of FMD; challenges and opportunities Keith Sumption, Secretary, European Commission for the Control of Foot-and-Mouth Disease (EuFMD), Food-and-Agriculture Organization

An Epitope Located at the C Terminus of Isolated VP1 of Foot-and-Mouth Disease Virus Type O Induces Neutralizing Activity but Poor Protection

J. gen. Virol. (1986), 67, 289-294. Printed in Great Britain Key words: FMD V/neutralizing activity/vp1 289 An Epitope Located at the C Terminus of Isolated VP1 of Foot-and-Mouth Disease Virus Type O Induces

Toward the control of Foot-and-Mouth disease in East Asia

Symposium on Prevention and Control of Foot and Mouth Disease and Highly Pathogenic Avian influenza in East Asia 20 September, 2017, Tokyo National Agriculture and Food Research Organization Toward the

WRLFMD: ~1000 samples from 36 countries January- December 2009 (300% up on 2008)

Appendix 9 IAH Pirbright FMD Reference Laboratory Report: 81st SESSION OF THE EXECUTIVE COMMITTEE OF THE EuFMD COMMISSION 2nd February 2011 Jef M. Hammond, Donald P. King, Nick J. Knowles, Jemma Wadsworth,

Rajesh Kannangai Phone: ; Fax: ; *Corresponding author

Amino acid sequence divergence of Tat protein (exon1) of subtype B and C HIV-1 strains: Does it have implications for vaccine development? Abraham Joseph Kandathil 1, Rajesh Kannangai 1, *, Oriapadickal

Elements of the FMD control problem in Southern Africa: 2

Elements of the FMD control problem in Southern Africa: 2 Gavin Thomson Commodity-based trade of beef and enhanced market access: The vital role of the Department of Veterinary Services Gaborone; 6-7 January

OIE Reference Laboratory Reports Activities

OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-12 10:32:31 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot

Bilateral cooperation between a laboratory in Korea and laboratories in other countries:

Bilateral cooperation between a laboratory in Korea and laboratories in other countries: the basis for a future extended network Yi Seok Joo DVM, Ph D National Veterinary Research and Quarantine Service

Laboratory tools for monitoring and understanding IBDV infection and vaccination

Laboratory tools for monitoring and understanding IBDV infection and vaccination J.J. (Sjaak) de Wit, DVM, PhD, dipl ECPVS GD Deventer, The Netherlands Gumboro-virus (IBDV) Avibirna-virus: segments of

COMPARISON OF DIFFERENT ELISA METHODS FOR THE DETECTION OF ANTIBODIES AGAINST FOOT-AND-MOUTH DISEASE VIRUS (FMDV) TYPE O

Bull. Vet. Inst. Pulawy 48, 5-9, 24 COMPARISON OF DIFFERENT ELISA METHODS FOR THE DETECTION OF ANTIBODIES AGAINST FOOT-AND-MOUTH DISEASE VIRUS (FMDV) TYPE O WIESŁAW NIEDBALSKI Department of Foot-and-Mouth

Evolution of influenza

Evolution of influenza Today: 1. Global health impact of flu - why should we care? 2. - what are the components of the virus and how do they change? 3. Where does influenza come from? - are there animal

Detection of vvibdv strains and Australian variants in poultry

Detection of vvibdv strains and Australian variants in poultry A report for the Rural Industries Research and Development Corporation by J. Ignjatovic, S. Sapats and G. Gould November 2001 RIRDC Publication

Application of Reverse Genetics to Influenza Vaccine Development

NIAID Application of Reverse Genetics to Influenza Vaccine Development Kanta Subbarao Laboratory of Infectious Diseases NIAID, NIH Licensed Vaccines for Influenza Principle: Induction of a protective

Vaccine matching. Reliability of foot-and-mouth disease r-values. determination

Vaccine matching Reliability of foot-and-mouth disease r-values determination Interinstitutional Network for R&D in FMD (RIIDFA)- Argentina Veterinary and Agrochemical Research Centre (VAR) - Belgium Protection

Requirements of the Terrestrial Code for FMD surveillance. Dr David Paton Dr Gideon Brückner

Requirements of the Terrestrial Code for FMD surveillance Dr David Paton Dr Gideon Brückner 1 Surveillance Close observation Origin of the word: Early 19th century: from French, from sur- over + veiller

This CRP is proposed for five years with three RCM. To apply, please see our website for directions:

1. CRP on the control of foot-and-mouth disease 2. Summary Foot-and-mouth disease (FMD) is one of the most important livestock diseases known to man due to its high infection rate (ease of spread) and

Are Dromedary Camels Susceptible or Non-Susceptible to Foot-and-Mouth Disease Serotype O

Are Dromedary Camels Susceptible or Non-Susceptible to Foot-and-Mouth Disease Serotype O Soren Alexandersen Danish Institute for Food and Veterinary Research Department of Virology, Lindholm DK-4771 Kalvehave,

FMD in Tunisia Update situation Critical review Vaccination programme

FMD in Tunisia Update situation Critical review Vaccination programme Workshop on FMD vaccination strategy in North Africa Tunis, 30 31 March 2016 Direction Générale Des Services Vétérinaires Contents

OIE Reference Laboratory Reports Activities

OIE Reference Laboratory Reports Activities Activities in 2014 This report has been submitted : 2015-01-16 03:37:00 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot

Materials and Methods

Appendix 18 Repeated administration of maximum payload emergency vaccines made from inactivated purified antigen concentrates do not induce significant titres of antibodies against non-structural proteins

Foot and Mouth Disease Control, A vaccine perspective. John Barlow, DVM PhD

Foot and Mouth Disease Control, A vaccine perspective John Barlow, DVM PhD john.barlow@uvm.edu May 28, 2015 Countries in which FMD was reported to the OIE between 1990 and 2002 Antigenic variation is common

OFFLU Technical Meeting Coordinating world-wide surveillance for influenza in swine OIE Paris, 6-7 April 2011

OFFLU Technical Meeting Coordinating world-wide surveillance for influenza in swine OIE Paris, 6-7 April 2011 Frank Wong CSIRO Australian Animal Health Laboratory, Geelong, Australia OIE Reference Laboratory

COMPARISON OF THREE ELISA KITS FOR THE DETECTION OF ANTIBODIES AGAINST FOOT-AND-MOUTH DISEASE VIRUS NON-STRUCTURAL PROTEINS

Bull Vet Inst Pulawy 49, 147-151 COMPARISON OF THREE ELISA KITS FOR THE DETECTION OF ANTIBODIES AGAINST FOOT-AND-MOUTH DISEASE VIRUS NON-STRUCTURAL PROTEINS WIESŁAW NIEDBALSKI Department of Foot-and-Mouth

Linking genetic and epidemiological datasets: the challenges of reconstructing transmission trees for livestock viral diseases

Linking genetic and epidemiological datasets: the challenges of reconstructing transmission trees for livestock viral diseases Donald King donald.king@pirbright.ac.uk Vesicular Disease Reference Laboratory

reads observed in trnas from the analysis of RNAs carrying a 5 -OH ends isolated from cells induced to express

Supplementary Figure 1. VapC-mt4 cleaves trna Ala2 in E. coli. Histograms representing the fold change in reads observed in trnas from the analysis of RNAs carrying a 5 -OH ends isolated from cells induced

HIV-1 resistance testing from proviral DNA

HIV-1 resistance testing from proviral DNA Alexander Thielen AREVIR 2018 Resistance testing from proviral DNA? amount of samples with low viral loads increasing desire to switch under successful therapy

FMD: Current Situation of Research and Research Needs

FMD: Current Situation of Research and Research Needs David Paton, Bryan Charleston, Terry Jackson, Jef Hammond OIE/FAO Global Conference on FMD, 24-26 June 2009, Paraguay Talk overview FMD research past

Llama single domain antibody fragments (VHHs) available at CVI:

Llama single domain antibody fragments (VHHs) available at CVI: VHH(s) Antigen specificity Cross-reaction Remarks Sequence Foot-and-mouth disease virus (FMDV) M3 FMDV, strain O1 Manisa O, A, C and Asia1

Appendix 81. From OPENFLU to OPENFMD. Open Session of the EuFMD: 2012, Jerez de la Frontera, Spain 1. Conclusions and recommendations

From OPENFLU to OPENFMD a resource for automatic and curated nomenclature and tools for the FMD community Filip Claes, Philippe Le Mercier, Dmitry Kuznetsov, Robin Liechti, Anne Gleizes, Ioannis Xenarios,

16 th JPC REMESA meeting

16 th JPC REMESA meeting Morocco, 18-19 April 2018 EuFMD support programme to REMESA Pillar II Reduced FMD risk to Members from European neighbourhood UPDATE September 2017 March 2018 Targets across the

Development and Current Situation FMD for Asia and the Pacific

Development and Current Situation FMD for Asia and the Pacific OIE Regional Workshop on Preparation and Submission of Dossiers for the Official Recognition of CFS and for the Endorsement of National Official

Novel FMD vaccine research in China

Novel FMD vaccine research in China International Conference on Scientific Developments and Technical Challenges in the Progressive Control of FMD in South Asia New Delhi, India 13-15 February, 2011 Dr.

Translation. Host Cell Shutoff 1) Initiation of eukaryotic translation involves many initiation factors

Translation Questions? 1) How does poliovirus shutoff eukaryotic translation? 2) If eukaryotic messages are not translated how can poliovirus get its message translated? Host Cell Shutoff 1) Initiation

Antigenic properties and virulence of foot-and-mouth disease virus rescued from full-length cdna clone of serotype O, typical vaccine strain

Brief communication CLINICAL EXPERIMENTAL VACCINE RESEARCH Clin Exp Vaccine Res 2;:-8 http://dx.doi.org/./cevr.2... pissn 228- eissn 228-X Antigenic properties and virulence of foot-and-mouth disease virus

1. Describe the relationship of dietary protein and the health of major body systems.

Food Explorations Lab I: The Building Blocks STUDENT LAB INVESTIGATIONS Name: Lab Overview In this investigation, you will be constructing animal and plant proteins using beads to represent the amino acids.

Rabies virus antigenicity: an overview

Onderstepoort Journal of Veterinary Research, 60:271-275 (1993) Rabies virus antigenicity: an overview PATRICE COULON, FLORENCE LAFAY and ANNE FLAMAND Laboratoire de Genetique des Virus, CNRS, 91198 GfF

http://www.ibs.upm.edu.my Challenges in controlling viral diseases of poultry Abdul Rahman Omar Institute of Bioscience Faculty of Veterinary Medicine Universiti Putra Malaysia aro@upm.edu.my Outline of

Cedivac-FMD; Duration of Immunity in cattle, sheep and pigs. 2004, 8203 AA Lelystad, The Netherlands * Corresponding Author

Appendix 3 Cedivac-FMD; Duration of Immunity in cattle, sheep and pigs. Paulus Selman *, Gilles Chénard and Aldo Dekker Animal Sciences Group, Wageningen UR, P.O. Box 65, 8 AB Lelystad, The Netherlands

Nucleotide Sequence of the Australian Bluetongue Virus Serotype 1 RNA Segment 10

J. gen. Virol. (1988), 69, 945-949. Printed in Great Britain 945 Key words: BTV/genome segment lo/nucleotide sequence Nucleotide Sequence of the Australian Bluetongue Virus Serotype 1 RNA Segment 10 By

Worldwide perspective on Infectious Bronchitis. Ruth Bouwstra, DVM, PhD Turkey February 2017

Worldwide perspective on Infectious Bronchitis Ruth Bouwstra, DVM, PhD Turkey February 2017 Infectious bronchitis virus Corona Virus, a ssrna virus - Relatively high rate of mutations (0,0012 subst per

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data

Computational Prediction of Broadly Neutralizing HIV-1 Antibody Epitopes from Neutralization Activity Data The MIT Faculty has made this article openly available. Please share how this access benefits

FMD regional update Gulf States 2017

FMD regional update Gulf States 2017 Nick Lyons on behalf of Donald King donald.king@pirbright.ac.uk WRLFMD Team: Valerie Mioulet, Nick Knowles, Anna Ludi, Ginette Wilsden, Bryony Armson, Pip Hamblin,

Foot-and Mouth Disease Ecological Studies In Endemic Settings: Ongoing Studies in Vietnam and Pakistan

Foot-and Mouth Disease Ecological Studies In Endemic Settings: Ongoing Studies in Vietnam and Pakistan Luis Rodriguez (Jonathan Arzt) Research leader, USDA-ARS Plum Island 1 PAKISTAN CHARACTERIZATION OF

Importance of cell mediated immunity for protection against Foot and Mouth Disease

Appendix 34 Importance of cell mediated immunity for protection against Foot and Mouth Disease Yooni Oh 1*, ryan Charleston 1, David J. Paton 1, Jong-Hyun Park 2, Paul V. arnett 1, Yi-Seok Joo 2, Satya

REGIONAL REFERENCE LABORATORY FOR FMD IN SOUTH EAST ASIA DEPARTMENT OF LIVESTOCK DEVELOPMENT PAKCHONG, NAKHONRATCHASIMA, THAILAND

University of Tokyo, Tokyo, Japan, 9-11 June 2015 REGIONAL REFERENCE LABORATORY FOR FMD IN SOUTH EAST ASIA DEPARTMENT OF LIVESTOCK DEVELOPMENT PAKCHONG, NAKHONRATCHASIMA, THAILAND Activities of FMD Laboratory

The Basics: A general review of molecular biology:

The Basics: A general review of molecular biology: DNA Transcription RNA Translation Proteins DNA (deoxy-ribonucleic acid) is the genetic material It is an informational super polymer -think of it as the

PRAGMATIST: A DECISION SUPPORT TOOL FOR FOOT AND MOUTH DISEASE VACCINE BANK MANAGERS

WHICH VACCINES ARE MOST IMPORTANT? PRAGMATIST: A DECISION SUPPORT TOOL FOR FOOT AND MOUTH DISEASE VACCINE BANK MANAGERS Melissa McLaws 1, Don King 2, Katie Hickey 1, Anna Ludi 2, Keith Sumption 1 European

Evolution of the Sabin Strain of Type 3 Poliovirus in an Immunodeficient Patient during the Entire 637-Day Period of Virus Excretion

JOURNAL OF VIROLOGY, Apr. 2000, p. 3001 3010 Vol. 74, No. 7 0022-538X/00/$04.00 0 Copyright 2000, American Society for Microbiology. All Rights Reserved. Evolution of the Sabin Strain of Type 3 Poliovirus

Structural comparison of two strains of foot-and-mouth disease virus subtype 01 and a laboratory antigenic variant, G67

Structural comparison of two strains of foot-and-mouth disease virus subtype 01 and a laboratory antigenic variant, G67 Susan Lea 1, 2, Robin Abu-Ghazaleh 3, Wendy Blakemore 3, Stephen Curry 3t, Elizabeth

YUMI YAMAGUCHI-KABATA AND TAKASHI GOJOBORI* Center for Information Biology, National Institute of Genetics, Mishima , Japan

JOURNAL OF VIROLOGY, May 2000, p. 4335 4350 Vol. 74, No. 9 0022-538X/00/$04.00 0 Copyright 2000, American Society for Microbiology. All Rights Reserved. Reevaluation of Amino Acid Variability of the Human

Q: If antibody to the NA and HA are protective, why do we continually get epidemics & pandemics of flu?

Influenza virus Influenza virus Orthomyxoviridae family of viruses RNA enveloped viruses that make up three genera Influenzavirus A Influenzavirus B Influenzavirus C The type A viruses are the most virulent

The Global FMD situation: SEACFMD in the Global Context

The Global FMD situation: SEACFMD in the Global Context Anna Ludi anna.ludi@pirbright.ac.uk WRLFMD Team: Donald King, Valerie Mioulet, Nick Knowles, Anna Ludi, Ginette Wilsden, Bryony Armson, Pip Hamblin,

Live Attenuated Influenza Vaccine. I. Background and Seasonal Vaccine

Live Attenuated Influenza Vaccine I. Background and Seasonal Vaccine Influenza infection stimulates multiple arms of the immune system Systemic antibody to HA and NA, and multiple internal proteins Mucosal

The inhibition of FMD virus excretion from the infected pigs by an antiviral agent, T-1105

The inhibition of FMD virus excretion from the infected pigs by an antiviral agent, T-1105 Appendix 64 Kenichi Sakamoto 1*, Seiichi Ohashi 1, Reiko Yamazoe 1, Kazumi Takahashi 2, and Yousuke Furuta 2 1

Diagnostic Methods of HBV and HDV infections

Diagnostic Methods of HBV and HDV infections Zohreh Sharifi,ph.D Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine Hepatitis B-laboratory diagnosis Detection

Rotavirus Genotyping and Enhanced Annotation in the Virus Pathogen Resource (ViPR) Yun Zhang J. Craig Venter Institute ASV 2016 June 19, 2016

Rotavirus Genotyping and Enhanced Annotation in the Virus Pathogen Resource (ViPR) Yun Zhang J. Craig Venter Institute ASV 2016 June 19, 2016 Loading Virus Pathogen Database and Analysis About Resource

NEXT GENERATION SEQUENCING OPENS NEW VIEWS ON VIRUS EVOLUTION AND EPIDEMIOLOGY. 16th International WAVLD symposium, 10th OIE Seminar

NEXT GENERATION SEQUENCING OPENS NEW VIEWS ON VIRUS EVOLUTION AND EPIDEMIOLOGY S. Van Borm, I. Monne, D. King and T. Rosseel 16th International WAVLD symposium, 10th OIE Seminar 07.06.2013 Viral livestock

Country Report on FMD in Uganda

Country Report on FMD in Uganda Dr. Ayebazibwe Chrisostom, PhD EARLN FMD Country Focal Person Uganda Ministry of Agriculture Animal Industry and Fisheries, Entebbe EARLN Meeting FMD 29 th August, 2013,

Keith Sumption Secretary, European FMD Control Commission (EuFMD) FAO, Rome

Foot and mouth disease situation and control strategies in Europe the current situation Keith Sumption Secretary, European FMD Control Commission (EuFMD) FAO, Rome The European neighborhood wider group

Results of Seromonitoring in FMD Buffer Zone in the CIS Countries

Appendix Results of Seromonitoring in FMD Buffer Zone in the CIS Countries T.A.Fomina, V.M.Zakharov, A.A.Gusev, N.E.Kamalova, S.R.Kremenchugskaya, O.A.Schekotova All-Russian Research Institute for Animal

DIFFERENTIATION OF INFECTION FROM VACCINATION BY DETECTION OF ANTIBODIES TO THE NON-STRUCTURAL PROTEIN 3ABC OF FOOT-AND-MOUTH DISEASE VIRUS

Bull. Vet. Inst. Pulawy 7, 5-6, DIFFERENTIATION OF INFECTION FROM VACCINATION BY DETECTION OF ANTIBODIES TO THE NON-STRUCTURAL PROTEIN ABC OF FOOT-AND-MOUTH DISEASE VIRUS WIESŁAW NIEDBALSKI AND BERND HAAS*

Amino Acids. Amino Acids. Fundamentals. While their name implies that amino acids are compounds that contain an NH. 3 and CO NH 3

Fundamentals While their name implies that amino acids are compounds that contain an 2 group and a 2 group, these groups are actually present as 3 and 2 respectively. They are classified as α, β, γ, etc..