UNIVERSITAS AIRLANGGA DIREKTORAT PENDIDIKAN Tim Pengembangan Jurnal Universitas Airlangga Kampus C Mulyorejo Surabaya

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2 EDITORIAL BOARD EDITORIAL BOARD OF DENTAL JOURNAL (MAJALAH KEDOKTERAN GIGI), January 2nd, 2014 December 31st, 2014 SK: 166/H3.1.2/KD/2014January 2nd, 2014 December 31st, 2014 Chief Editor :Udijanto Tedjosasongko, drg., Ph.D.,Sp.KGA(K) (Department of Pediatric Dentistry Universitas Airlangga ) Editorial Boards : Prof. Nairn Hutchinson Fulton Wilson, MSc. Ph.D., FDS. (Department of Conservative Dentistry - University of Guy s Dental School, London) Prof. W.J. Spitzer, DMD., MD. (Department of Cranio & Oral Maxillofacial Surgery Hamburg University, Germany) Prof. Edward C. Combe. M.Sc. Ph.D. D.D.Sc. (Department of Biomaterial Minnesota University, U.S.A) Prof. Madya. H. AB. Rani Samsudin D.D.S., FDSRC, AM. (Department of Oral and Maxillofacial Surgery -University Science Malaysia, Malaysia) Prof. Taizo Hamada, D.D.S., Ph.D. (Department of Prosthodontic - Tohoku University, Japan) Prof. Yukio Kato, D.D.S., Ph.D. (Department of Oral Bio Chemistry-University of Hiroshima, Japan) Prof. dr. A.G.M. Tielens (Department of Medical Microbiology and Infections Disease - Erasmus University Medical centre, Rotterdam, the Netherlands) Prof. Lakshman Samaranayake (Department of Oral Microbiology The University of Hongkong) Prof. Kozai Katsuyuki, DDS.,Ph.D. (Department of Pediatric - University of Hiroshima, Japan) Prof. dr. A.G.M. Tielens (Department of Medical Microbiology - University and Infections Diseases - erasmus University Medical Centre, Rotterdam, The Netherlands) Kok Van Kessel (Department of Medical Microbiology and Infections Disease - Erasmus University Medical centre, Rotterdam, the Netherlands) Dr. Leslie Ang (Department of Restorative Dentistry National Dental Centre of Singapore) Prof. Widowati Witjaksono, drg., Ph.D. (Kulliyah of Dentistry, International Islamic University Malaysia) Prof. Dr. M. Suharsini, drg, M.S., Sp. KGA. (Department of Pediatric Dentistry - Universitas Indonesia) Achmad Gunadi, drg, M.S., Ph.D. (Department of Prosthodontic Universitas Jember) Managing Editors : Prof. Dr. M Rubianto, drg, M.S., Sp. Perio. (Department of Periodontic Universitas Airlangga) Prof. Dr. Latief Mooduto, drg, M.S., Sp. KG. (Department of Conservative Dentistry Univ. Airlangga) Prof. RM. Coen Pramono, drg., SU., Sp.BM(K) (Department of Oral and Maxillofacial Surgery - Univ. Airlangga) Prof. Dr. Mieke Sylvia M. A. R., drg, M.S.,Sp.Ort. (Department of Ortodontic Univ. Airlangga) Prof. Dr. Istiati, drg, M.S. (Department of Oral Pathology and Maxillofacial Univ. Airlangga) Prof. Dr. Anita Yuliati, drg, M.Kes. (Department of Dental Material Univ. Airlangga) Prof. Seno Pradopo, drg, S.U., Ph.D. Sp. KGA. (Department of Pediatric Dentistry Univ. Airlangga) Prof. Dr. Diah Savitri Ernawati, drg., M.Si. (Department of Oral Medicine Univ. Airlangga) Prof. Thalca I. Agusni, drg, MHPEd. Ph.D.,Sp.Ort. (Department of Orthodontic Univ. Airlangga) Dr. R. Darmawan Setijanto, drg.,m.kes. (Department of Dental Public Health Univ. Airlangga) Dr. Elly Munadziroh, drg.,ms (Department of Dental Material Universitas Airlangga) Ketut Suardita, drg., Ph.D., Sp.KG(Department of Conservative Dentistry-Univ. Airlangga) Priyawan Rachmadi, drg, Ph.D. (Department of Dental Material Univ. Airlangga) Dr. Retno Pudji Rahayu, drg., M.Kes. (Department of Oral Pathology and Maxillofacial Univ. Airlangga) Dr. Eha Renwi Astuti, drg., M.Kes (Department of Dental Radiology Univ. Airlangga) Bagus Soebadi, drg, MHPEd. (Department of Oral Medicine Univ. Airlangga) Markus Budi Rahardjo, drg.,m.kes. (Department of Oral Biology Univ. Airlangga) Dr. Susy Kristiani, drg., M.Kes. (Department of Odontology Forensic Univ. Airlangga) Dr. Ira Widjiastuti, drg, M.Kes.Sp.KG. (Department of Conservative Dentistry Univ. Airlangga) Sianiwati Goenharto, drg., M.S. (Department of Ortodontic Univ. Airlangga) Devi Rianti, drg, M.Kes. (Department of Dental Material Univ. Airlangga) Dr. Chiquita Prahasanti, drg.,sp.perio. (Department of Periodontic Univ. Airlangga) Rostiny, drg.,m.kes.,sp.pros. (Department of Prosthodontic Univ. Airlangga) An nissa Chusida, drg.,m.kes (Department of Odontology Forensic Univ. Airlangga) Eric Priyo Prasetyo, drg., Sp.KG. (Department of Conservative Dentistry Univ. Airlangga) Els Sunarsih Budipramana, drg., MS.,Sp.KGA.(K). (Department of Pediatric Dentistry Univ. Airlangga) Dr. Hendrik Setiabudi, drg., M.Kes (Department of Oral Biology Univ. Airlangga) Anis Irmawati, drg.,m.kes. (Department of Oral biology Univ. Airlangga) Yuliati, drg.,m.kes. (Department of Oral Biology Univ. Airlangga) Retno Palupi, drg.,m.kes. (Department of Dental Public Helath Univ. Airlangga) Eka Augustina, drg.,sp.perio. (Department of Periodonsia Univ. Airlangga) Febriastuti, drg.,sp.kg. (Department of page 2 / 5

3 Conservative Dentistry Univ. Airlangga) Mega M. Puteri, drg.,sp.kga. (Department of Pediatric Dentistry Univ. Airlangga) Administrative Assistant :Novi Dian Prastiwi (Faculty of Dentistry Airlangga University) page 3 / 5

4 Table of Contents No Title Page 1 Potential of extracts cassava leaf (Manihot utilissima) on the expression of COX-2 on 0-0 monocytes that exposed by LPS E. coli 2 The effect of desensitizing agent containing fluoride on Streptococcus mutans 0-0 adhesion and enamel roughness 3 Physical properties of calcite synthesized hydroxyapatite as the filler of 0-0 epoxy-resin-based root canal sealer 4 Ekspresi COX-2 setelah pemberian ekstrak etanolik kulit manggis Prevotella intermedia and porphyromonas gingivalis in dental caries with periapical 0-0 granuloma 6 Facial soft tissue profile on borderline class I malocclusion between extraction and 0-0 non-extraction orthodontic treatment 7 Fish oil of Sardinella longicep regulates osteoblast apoptosis of rat alveolar bone induced lypopolisacharide Inflammatory response of the dental pulp after application of 19% ethylene diamine tetraacetic acid and 37% phosphoric acid as etching agents 9 Antifungal property of Sticophus hermanii and Holothuria atra extract and its cytotoxicityto gingiva-derived mesenchymal stem cell Orthodontic-surgical treatment of a severe class III malocclusion Perbandingan korelasi antara indeks morfologi wajah genap dengan sudut interinsisal dan tinggi wajah secara sefalometri page 4 / 5

5 Powered by TCPDF ( Vol No. 4 / TOC : 4, and page : Inflammatory response of the dental pulp after application of 19% ethylene diamine tetraacetic acid and 37% phosphoric acid as etching agents Respon inflamasi pada pulpa gigi setelah aplikasi bahan etsa ethylene diamine tetraacetic acid 19% dan asam fosfat 37% Author : Nadie Fatimatuzzahro nadiefatima@gmail.com Bagian Biomedik Gigi, Fakultas Kedokteran Gigi, Universitas Jember, Jember-Indonesia Tetiana Haniastuti haniastuti@yahoo.com Bagian Biologi Oral, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta - Indonesia Juni Handajani junihandajani@yahoo.com Bagian Biologi Oral, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta - Indonesia Abstract Background:Etching agents such as ethylene diamine tetraacetic acid (EDTA) and phosphoric acid which are widely used in adhesive restoration system are aimed to increase retention of restorative materials; however, these agents may induce inflammation of dental pulp. The major function of the inflammatory response is to clear invading pathogens or damaged tissue/ cells and therefore, initiate repair. Neutrophils and macrophages are motile phagocytes that constitute the body s first line of defense. Purpose:The purpose of the present research was to study the effect of 19% EDTA and 37% phosphoric acid application as an etching agents on the inflammatory response of the dental pulp. Methods:Forty-five male Sprague Dawley rats were divided into 3 groups. Cavity preparation was made on the occlusal surface of maxillary first molar using a round diamond bur. 19% EDTA, 37% phosphoric acid, and distilled water were applied on the surface of the cavity of the teeth in group I, II and III subsequently. The rats were sacrified at 1, 3, 5, 7, and 14 days after the application (n=3 for each day). The specimens were then processed histologically and stained with hematoxylin eosin. results: ANOVA showed a significant difference (p<0.05) among treatment groups, indicating that etching agents application induced neutrophils, macrophages and lymphocytes infiltration in the dental pulp. Tuckey HSD test showed that application of 37% phosphoric acid increased higher number of neutrophils, macrophages and lymphocytes significantly than 19% EDTA (p<0.05). Conclusion:In conclusion, 37% phosphoric acid induced higher number of the inflammatory cells than 19% EDTA. Keyword :, 19%, EDTA,, 37%, phosphoric, acid,, inflammation, dental,, Daftar Pustaka : 1. Roberson TM, (2006). Sturdevant s art and science of operative dentistry. St. Louis : Mosby Elsevier Empty Fullpaper page 5 / 5

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