Agenda* The 9th International Congress on Cutaneous Adverse Drug Reactions (iscar 2015)

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1 1 of 5 Agenda* The 9th International Congress on Cutaneous Adverse Drug Reactions (iscar 2015) Co-chairs: Dr. Neil H. Shear at the 23rd World Congress of Dermatology in Vancouver, Canada. Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto Medical School. Toronto, Canada. Dr. Wen-Hung Chung The Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Chang Gung University. Taoyuan, Taiwan Vice-chair: Dr. Roni P. Dodiuk-Gad Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada. Ha emek Medical Center, Afula, Israel. Time Topic Speaker Affiliation 8-8:15am Opening remarks Dr. Neil H. Shear Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada Pharmacogenomics and Severe Cutaneous Adverse Drug Reactions (SCAR) Dr. Lois A La Grenade - Division of Pharmacovigilance, Office of Surveillance & Epidemiology, Center for Drug Evaluation & Research, US FDA, Silver Spring, USA Dr. Simon A. Mallal - Institute for Immunology and Infectious Diseases, Murdoch University, Western Australia 8:15-8:30am HLAs and SCAR- Dr. Elizabeth Phillips Vanderbilt University Medical Center, Nashville, TN, USA, and the Institute for Immunology and Infectious Diseases, Murdoch, WA, Australia

2 2 of 5 8:30-8:45am Pharmacovigilance Dr. Lois A La Grenade Division of Pharmacovigilance, Office of Surveillance & Epidemiology, Center for Drug Evaluation & Research, US FDA, Silver Spring, USA 8:45-9:00am Pathomechanism of allopurinol-induced hypersensitivity reactions Dr. Shuen-Iu Hung Department & Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan 9:00-9:15am 9:15-9:30am 9:30-9:45am Pharmacogenomics and SCAR- Q+A Dr. Lois A La Grenade, Dr. Simon A. Mallal iscar 2015 Group Consensus on Pharmacogenomics and SCAR Coffee Break Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)/ Drug-Induced Hypersensitivity Syndrome (DIHS) Dr. Eishin Morita - Shimane University Faculty of Medicine, Shimane, Japan Dr. Sylvia H. Kardun - University Medical Center Groningen, Reference Center for cutaneous adverse drug reactions, Groningen, The Netherlands 9:45-10:00am 10:00-10:15am 10:15-10:30am DRESS /DIHS- Pathogenesis- DRESS/DIHS- Clinical aspects and In vitro tests- DRESS/DIHS short and long term complications Dr. Tetsuo Shiohara Dr. Sima Halevy Dr. Yoko Kano Kyorin University School of Medicine, Tokyo, Japan Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel Kyorin University School of Medicine, Tokyo, Japan 10:30-10:45am Management of DRESS - cutaneous adverse drug reaction working group of the French Society of Dermatology Dr. Annick Barbaud Dermatology and Allergy Department, Brabois Hospital, University Hospital of Nancy, Lorraine University, France

3 3 of 5 10:45-11:00pm 11:00-11:15 11:15-12:00pm DRESS /DIHS Q+A Dr.Eishin Morita, Dr. Sylvia H. Kardaun iscar 2015 Group Consensus on DRESS /DIHS Lunch break Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis (SJS/TEN) Dr. Jean-Claude Roujeau - Université Paris-Est Créteil (UPEC), France Dr. Abe Riichiro - Hokkaido University Graduate School of Medicine, Sapporo, Japan 12:00- Dr. Maja 12:15pm Mockenhaupt 12:15-12:30 pm 12:30-12:45pm Stevens-Johnson syndrome and toxic epidermal necrolysis- Epidemiology and clinical presentation- Stevens-Johnson syndrome and toxic epidermal necrolysis- Pathogenesis and Treatment- IVIG clinical trial for SJS/TEN in Japan Dr. Wen-Hung Chung Dr. Michiko Aihara University Freiburg Medical Center, Freiburg, Germany Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospitals, Taipei, Linkou, and Keelung, Taiwan Yokohama City University School of Medicine, Kanagawa, Yokohama, Japan 12:45-1:00pm 1:00-1:15pm Anti-TB drugs induced Stevens- Johnson syndrome and toxic epidermal necrolysis: Clinical assessments and genetic links Recurrence and mortality following SJS/TEN Dr. Rannakoe J. Lehloenya Dr. Yaron Finkelstein Division of Dermatology, Department of Medicine, University of Cape Town, South Africa Paediatric Emergency Medicine Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada.

4 4 of 5 1:15-1:30 pm 1:30-1:45pm SJS/TEN Q+A Dr. Jean-Claude Roujeau, Dr. Abe Riichiro iscar 2015 Group Consensus on SJS/TEN Acute Generalised Exanthematous Pustulosis (AGEP) Dr. Pierre Wolkenstein - Division Cancers Immunity Transplantation Infections, Henri- Mondor Hospital, University Paris Est Créteil, Créteil Cedex France 1:45- Dr. Lars E. 2:00pm French 2:00-2:15pm 2:15-2:30pm 2:30-2:45pm 2:45-3:00pm 3:00-3:20pm Acute generalized exanthematous pustulosis- A diagnostic challenge: AGEP Vs other pustular eruptions Systemic involvement of acute generalized exanthematous pustulosis Dr. Batya Davidovici Dr. Claire Hotz Department of Dermatology Zurich University Hospital, Zürich, Switzerland Depatment of Dermatology, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel AP-HP, Hôpital Henri-Mondor, Créteil, France AGEP Q+A Dr. Pierre Wolkenstein iscar 2015 Group Consensus on AGEP Coffee Break More cutaneous adverse drug reactions Dr.Rosaline Hui - Chang Gung Memorial Hospital at Taipei, Taiwan Dr. Chih-Hsun Yang - Chang Gung Memorial Hospital, Taipei, Taiwan 3:20-3:35pm 3:35-3:50pm Dermatologic Side Effects of Cancer Treatment Causality in ADR Dr. Mario E. Lacouture Dr. Raed Alhusayen Memorial Sloan Kettering Cancer Center, NYC, USA Division of Dermatology, Department of Medicine, Sunnybrook Health Sciences

5 5 of 5 Centre, University of Toronto, Toronto, Canada 3:50-4:05pm 4:05-4:20pm 4:20-5pm In vitro and In vivo assessments for SCAR- Dr. Marc Vocanson INSERM U851, IFR 128, BioSciences Lyon-Gerland, Lyon Cedex, France. More cutaneous adverse drug reactions Q+A Rosaline Hui, Dr. Chih-Hsun Yang Closing Remarks, Distinguished Contribution Awards Ceremony and Group Photo Presented by Dr. Wen-Hung Chung and Dr. Neil H. Shear *Not all speakers are confirmed. Topics and speakers may change.

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