XIANG QI WERDICH, MD PhD

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1 XIANG QI WERDICH, MD PhD December 15, 2014 Office Address 243 Charles Street, Boston, MA Phone Number EDUCATION 1997 MD Peking University Health Science Center Medicine 2000 MA Vanderbilt University Neuroscience, Vision Science, Retinal Angiogenesis 2005 PhD Vanderbilt University Cell and Developmental Biology, Vision Science, Retinal Angiogenesis POSTDOCTORAL TRAINING Research Fellowship Vanderbilt University School of Medicine Vanderbilt Eye Institute Clinical Research Fellowship Beth Israel Deaconess Medical Center Internship in Transitional Medicine MetroWest Medical Center Residency in Ophthalmology Cleveland Clinic Cole Eye Institute Clinical Fellowship in Ophthalmic Pathology Clinical Fellowship in Inherited Retinal Degenerations and Pediatric Medical Retina 1

2 ACADEMIC APPOINTMENTS Boston Children s Hospital 2015 Present Instructor in Ophthalmology Massachusetts General Hospital MEDICAL LICENSES Massachusetts Medical License California Medical License AMERICAN BOARD OF OPHTHALMOLOGY Written Qualifying Examination March 25, 2014 Oral Examination June 5-7, 2015 MEMBERSHIPS IN PROFESSIONAL SOCIETIES American Academy of Ophthalmology (AAO) American Society of Cataract and Refractive Surgery (ASCRS) Association for Research in Vision and Ophthalmology (ARVO) EXAMINATIONS AND CERTIFICATES United States Medical Licensing Examinations (USMLEs) Educational Commission for Foreign Medical Graduates (ECFMG) Certificate HONORS AND AWARDS Vanderbilt University graduate scholarships and research fellowships 2004 Vanderbilt University graduate student travel award 2005 Vanderbilt University graduate student travel award 2005 Association for Research in Vision and Ophthalmology (ARVO) Foundation / Retina Research Foundation / Joseph M. and Eula C. Lawrence travel scholarship award PUBLICATIONS 1. Bullard LE, Qi X, Penn JS. Role for extracellular signal-responsive kinase-1 and -2 in retinal angiogenesis. Invest Ophthalmol Vis Sci. 2003;44(4):

3 2. Werdich XQ, McCollum GW, Rajaratnam VS, Penn JS. Variable oxygen and retinal VEGF levels: correlation with incidence and severity of pathology in a rat model of oxygen-induced retinopathy. Exp Eye Res. 2004;79: Werdich XQ, Penn JS. Src, Fyn and Yes play differential roles in VEGF-mediated endothelial cell events. Angiogenesis. 2005;8(4): Penn JS, McCollum GW, Barnett JM, Werdich XQ, Koepke KA, Rajaratnam VS. Angiostatic effect of penetrating ocular injury: role of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci. 2006;47(1): Chen J, Hicks D, Brantley-Sieders D, Cheng N, McCollum GW, Qi-Werdich X, Penn J. Inhibition of retinal neovascularization by soluble EphA2 receptor. Exp Eye Res. 2006;82(4): Werdich XQ, Penn JS. Specific involvement of Src family kinase activation in the pathogenesis of retinal neovascularization. Invest Ophthalmol Vis Sci. 2006;47(11): Senapati GM, Levine D, Smith C, Estroff JA, Barnewolt CE, Robertson RL, Poussaint TY, Mehta TS, Werdich XQ, Pier D, Feldman HA, Robson CD. Frequency and cause of disagreements in imaging diagnosis in children with ventriculomegaly diagnosed prenatally. Ultrasound Obstet Gynecol. 2010;36(5): Werdich XQ, Lowder CY, Singh AD. Necrotising scleritis, up to half of patients with this condition have an underlying systemic disease. Advanced Ocular Care. 2010;5/6: Pier DB, Levine D, Kataoka ML, Estroff JA, Werdich XQ, Ware J, Beeghly M, Poussaint TY, Duplessis A, Li Y, Feldman HA. Magnetic resonance volumetric assessments of brains in fetuses with ventriculomegaly correlated to outcomes. J Ultrasound Med. 2011;30(5): Werdich XQ, Ruez T, Singh RP. Prevalence and severity of blepharitis symptoms and signs amongst patients with age-related macular degeneration. J Clinic Experiment Ophthalmol. 2011;2(4): Nguyen TM, Phelan MP, Werdich XQ, Rychwalski PJ, Huff CM. Subconjunctival hemorrhage in a patient on dabigatran (Pradaxa). Am J Emerg Med. 2013;31(2):455e Werdich XQ, Jakobiec FA, Singh AD, Kim IK. A review of advanced genetic testing for clinical prognostication in uveal melanoma. Semin Ophthalmol. 2013;28(5-6): Jakobiec FA, Werdich XQ. Androgen receptor identification in the diagnosis of eyelid sebaceous carcinomas. Am J Ophthalmol. 2014;157(3):

4 14. Jakobiec FA, Werdich XQ, Chodosh J, Freitag SK. An analysis of conjunctival and periocular venous malformations: clinicopathologic and immunohistochemical features with a comparison of racemose and cirsoid lesions. Surv Ophthalmol. 2014;59(2): Chen X, Jakobiec FA, Yadav P, Werdich XQ, Fay AM. Melkersson-Rosenthal syndrome with isolated unilateral eyelid edema: an immunopathologic study. Ophthal Plast Reconstr Surg. 2014;30(3): Werdich XQ, Jakobiec FA, Curtin HD, Fay AM. A clinical, radiologic, and immunopathologic study of five peri-orbital intraosseous cavernous vascular malformations. Am J Ophthalmol. 2014;158(4): Werdich XQ, Place EM, Pierce EA. Systemic diseases associated with retinal dystrophies. Semin Ophthalmol. 2014;29(5-6): CONFERENCE ABSTRACTS 1. Qi X, Percinel PA, Carlisle CD, Rajaratnam VS, Penn JS. Can retinal VEGF levels explain paradoxes associated with variable oxygen-induced retinopathy? Invest Ophthalmol Vis Sci. 2001;42: Penn JS, Qi X, Percinel PA, Rajaratnam VS, Bingaman DP. Studies of the effect and mechanism of action of topical Nepafenac in a rat model of ROP. Invest Ophthalmol Vis Sci. 2002;43: Penn JS, Hicks D, McCollum GW, Rajaratnam VS, Qi X, Chen J. A soluble ephrin receptor blocks angiogenic responses in retinal endothelial cells and inhibits neovascularization in a rat ROP model. Invest Ophthalmol Vis Sci. 2003;44: Qi X, Sarthy VP, Penn JS. VEGF induction by hypoxia in Müller cells. Invest Ophthalmol Vis Sci. 2004;45: Fowler JA, Barnett JM, Werdich XQ, Yang R, Penn JS. Matrix metalloproteinase-2 and -9 knockout mice are resistant to oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2005;46: Werdich XQ, Penn JS. Src family kinases, new therapeutic targets for intervention of VEGF-mediated retinopathy. Invest Ophthalmol Vis Sci. 2005;46: Malik G, Levine D, Camala S, Estroff J, Robertson R, Robson CD, Werdich XQ, Barnewolt CE, Poussaint TY. Frequency and etiology of postnatal ultrasound and MR imaging disagreements in diagnoses for fetuses with prenatally diagnosed ventriculomegaly. The Radiological Society of North America (RSNA)

5 8. Werdich XQ, Ruez T, Singh R. Prevalence and severity of blepharitis symptoms and signs amongst patients with age-related macular degeneration. Invest Ophthalmol Vis Sci. 2010;46: Werdich XQ, Cutler A, Lauer M, Hascall V, Shadrach KG, Lessieur E, Traboulsi E, Crabb JW, Hollyfield JG, Anand-Apte B. Significance of hyaluronan in the pathogenesis of choroidal neovascularization in advanced age-related macular degeneration. ARVO Werdich XQ, Ali M, Anand-Apte B. Vascular endothelial growth factor-a mediates inflammatory cell recruitment in the cornea. ARVO

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