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1 No-Varix Graduated Compression Hosiery is manufactured by TEXPON S.A., the only Latin- American company certified with the norm ISO 9001:00 with scope of manufacture of graduate compression hosiery for prevention and treatment of the varicose veins. Latmedical, LLC is the exclusive Caribbean distributor

2 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

3 Anatomy Systems of Vessels Endothelium Vein Externa Media (Muscle) Artery Venules Arterioles Capillaries

4 Anatomy Systems of Vessels: Arteries, veins and capillaries Arteries Oxygen transport High pressure, low volume system Thick specialised elastic vessel walls Damage, destruction, or removal of an artery will result in death of tissue Veins Carbon dioxide transport Low pressure, high volume system (four times as much blood as arterial system) Thinner vessel walls Can be damaged / destroyed / removed without death of tissue Capillaries Smallest vessels of the circulatory system Exchange of blood between the arterial and venous system Walls consist of a single layer of endothelium One blood cell channel Carry out circulatory functions Imbalance of processes can lead to oedema Vast Network

5 Anatomy Varicose Veins Varicose veins are veins that have become enlarged and twisted. One cause of valve failure is deep vein thrombosis (DVT), which can cause permanent damage to the valves. The blood collects in the veins and they enlarge even more. Varicose veins are common in the superficial veins of the legs, which are subject to high pressure when standing. Besides cosmetic problems, varicose veins are often painful, especially when standing or walking. They often itch, and scratching them can cause ulcers. Serious complications are rare.

6 Veins have leaflet valves to prevent blood from flowing backwards (retrograde). Leg muscles pump the veins to return blood to the heart. When veins become enlarged, the leaflets of the valves no longer meet properly, and the valves don't work. Thin, transparent cusp like structure Promote unidirectional flow More numerous in the distal leg Number varies individually Anatomy Venous Valves Insufficiency primary factor in Chronic Venous Insufficiency (CVI) Venous valves prevent reverse blood flow Cross section of a vein showing a valve which prevents backflow

7 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

8 Varicosis Varicosis in general refers to distended veins. It derives from the Latin word for twisted, "varix". Types of varices include: Varicose veins of lower extremities Gastrointestinal varices Scrotal varices (varicocele)

9 Varicosis How they are originated? A failure of the venous wall Expanssion of the vein The closure of the venous valves are incompetent Defect of a single perforator vein Blood flows Venous pressure increases Possible consequences of the varicosis

10 Varicosis Types Telangiectasias Spider veins Varicose veins of lateral branches Varices tronculares

11 Varicosis Symtoms and consequences of Neglecting varices Ulcers Tiredness in lower extremeties Frequent Cramping Numbness in the legs Leg pain Edema Telangiectasias Varices Edemas

12 Varicosis Risk Factors Advanced age Obesity Inheritance (Family history) Foot position Sitting position Sedentary

13 Varicosis Risk Factors High-heels Exercise absence Pregnancy Sun heat Fit-tight clothing Contraceptives pills

14 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

15 Graduated Compression Graduated compression forces veins to compress in their normal diameter so that the valves operate normally. The effect is to increase the velocity of blood flow and counteract the increased venous pressure, combined on the macro and micro circulation explains the effectiveness of treatment. Compression stockings are used to support the venous and lymphatic systems of the leg. They offer graduated compression where maximum compression is achieved at the ankle and decreases as you move up the leg. This compression, when combined with the muscle pump effect of the calf, aids in circulating blood and lymph fluid through the legs. Today, compression stockings are available in a wide range of opacities, colors, styles and sizes, making them virtually indistinguishable from regular hosiery or socks.

16 Graduated Compression Prevents... venous return, preventing inflammation and pain, for this reason graduated compression is a therapy more effective and efficient in the prevention and treatment of venous insufficiency and varicose disease

17 Graduated Compression How it works? compression hosieries are the best choice in the prevention and treatment of varicose veins, medically designed with advanced technology and raw materials of last generation. Reduces the action and effect of risk factors, stimulating blood circulation in the legs, eliminating fatigue, pain, inflammation and cramps Maximum compression at the ankle, gradually decreasing up the leg Compression decreases gradually towards the heart

18 Graduated Compression How it works? Without medicated compression hoiseiry With medicated compression hoiseiry

19 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

20 Grades of Compressions Low Compression Medium Compression Firm Compression Extra Firm Compression 10-15mmHg 15-20mmHg 20-30mmHg 30-40mmHg

21 Low Compression 10-15mmHg Prevention and treatment of mild varicose veins, relieve inflammation, pain, fatigue, tiredness, heaviness and cramps. Indications Prophylactic Primary varicose veins Class A Telangiectasia, localized and diffuse Styles Knee Pantyhose

22 Med. Compression 15-20mmHg Relieve inflammation, pain, fatigue, tiredness, heaviness and cramps. Help prevent T.V.P. Indications Therapeutics Class B Reticular veins, localized and diffuse Styles Knee Thigh Pantihose Socks

23 Firm Compression 20-30mmHg Inflammation and pain control, pre and postsurgical Indications Therapeutics Class C Veins trunculares Styles Knee Thigh Pantihose Socks Tights for men

24 X-Firm Compression 30-40mmHg Control pain, inflammation and prevents of venous insufficiency before and after surgery. Indications Therapeutics Lymphoedema of any etiology Styles Knee Thigh

25 Lymphedema Sleeve 30-40mmHg Mastectomy: Surgical procedure that is performed to control breast cancer, currently in some countries reaching up to 19%. Usually, this surgery affects the lymphatic system and this is why No-Varix arm slevee graduated compression is essential for treatment. Indications Therapeutics Lymphoedema of any etiology Post-mastectomy Post-radiotherapy

26 T.V.P. Anti-Embolism Stockings Reduces the risk of pulmonary embolism, deep vein thrombosis and varicotrombosis D.V.T. Indications Therapeutics Pre and Post-sugery Styles Knee Thigh (with and without belt)

27 T.V.P. Anti-Embolism Stockings In all surgeries, it is protocol in many hospitals around the world, the use of averages antiembolicas to prevent deep vein thrombosis D.V.T. There have been several deaths by D.V.T. staying in bed, during and after the procedures, venous stasis occurs and is a cause for thrombus, which can be detached from the walls of the veins and travel to the lungs or brain, the use of aid to increase the speed of the blood flow is a common worldwide method used, helping to prevent D.V.T.

28 Travel SOCKS Your best choice! It has been scientifically proven that people can develop DVT (Deep venous thrombosis or economy class syndrome) for being seated for long stay positions forced on long journeys The use of Travel SOCKS compression stockings helps to prevent this problem and immediately relieves pain, tiredness, heaviness and swelling in the legs caused by venous disorders Travel SOCKS graduated compression stockings facilitates blood circulation and prevents the formation of clots or thrombi; daily use is essential and gives you comfort and rested legs. Consult your doctor.

29 13-18mmHg Orange Yellow Violet White Pistacho Fucsia Pink L/Blue New No-Varix product, at the request of users.

30 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

31 Competition Worldwide

32 Competition Worldwide

33 Competition Local in LatAm Sanciro Ke-nal Regina Venasan Prevent Lauda Therafirm Gabriela Itamed Kendal Colombia México México Guatemala U.S.A. Argentina U.S.A. U.S.A. Brasil

34 Agenda Anatomy Varicosis Graduated Compression Grades of Compressions Competition How to Sell No-Varix

35 How to sell No-Varix All rear packages have the sizing instructions on how you should size according to height and weight, is a universal table, no problem at the time of sale. Swatchs half transparent and half-colors. Even-though all packages have care instructions, it is recommended for the medical representatives to indicate that this items are considered delicate and should be treated as such.

36 Thank you

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