LV Function Cardiac Output EPSS

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1 LV Function Cardiac Output EPSS Mike Mallin, MD

2 Why is LV function important? Systolic Dysfunction is bad... Is it worse? Is it the cause of my patients dyspnea? Does my patient need a inotrope? Why is this person hypotensive?

3 Fluid Responsive Fluid Responsive: A volume load Mike should induce a significant increase in cardiac output. 500cc-1L Matt 10-15% CO

4 Measuring CO How to measure SV/CO: SV = Length area SV = LVOTVTI r 2 CO = LVOTVTI r 2 HR

5 Stroke Volume CO = LVOTVTI r 2 HR Column of blood

6 CO = LVOT VTI r 2 HR Stroke Volume

7 CO = LVOT VTI r 2 HR Stroke Volume

8 CO = LVOT VTI r 2 HR Stroke Volume

9 CO = LVOT VTI r 2 HR Stroke Volume

10 CO = LVOT VTI r 2 HR Stroke Volume

11 CO = LVOT VTI r 2 HR Stroke Volume

12 Stroke Volume CO = LVOTVTI r 2 HR How to measure SV/CO: SV = LVOTVTI r 2 SV = Volume of Column of blood: Length of column x area

13 Stroke Volume Area Circle = r 2

14 Stroke Volume Area Circle = r 2

15 LVOT Diameter Measuring the LVOT: PSLX

16 LVOT Diameter Measuring the LVOT: PSLX RVOT Ao LV LA

17 LVOT Diameter Measuring the LVOT: PSLX RVOT Ao LV LA

18 LVOT Diameter Measuring the LVOT

19 LVOT Diameter Measuring the LVOT

20 LVOT Diameter Measuring the LVOT

21 LVOT Diameter Measuring the LVOT LVOTdiameter

22 LVOT Diameter Measuring the LVOT

23 SV Measurement Still need the length of the column L D

24 SV Measurement Still need the length of the column L D

25 SV Measurement Still need the length of the column L D

26 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window

27 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window Place Pulsed Wave gate at LVOT Just apical from the AoValve

28 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window

29 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window

30 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window

31 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window

32 LVOT VTI (length of column) Measuring the LVOTVTI: Apical Long Axis or Apical 5 chamber window Place Pulsed Wave gate at LVOT Just apical from the AoValve

33 LVOT VTI (length of column) Measuring the LVOTVTI

34 Passive Leg Raise Testing Semirecumbent patient Measure CO/SV at baseline Raise legs by Repeat CO/SV measurement

35 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR

36 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR

37 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR

38 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR

39 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR

40 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR LVOTVTI : LVOTVTI-PLR

41 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR LVOTVTI : LVOTVTI-PLR

42 Passive Leg Raise Testing Who cares what the CO is? I want to know if they are a responder! CO=SV HR CO PLR=SVPLR x HRPLR LVOTVTI r 2 x HR : LVOTVTI-PLR r 2 x HRPLR LVOTVTI : LVOTVTI-PLR

43 confusid?

44 Need less information? Just want to know: Is the pump working?

45 Leg raise?

46 LV Function Measuring EF: Eyeball Fractional Shortening Method of Discs Tricks -- EPSS

47 The Eyeball Method

48 Eyeballin Not always this obvious

49 Easy when...

50 Hard when...

51 Hard when...

52 Eyeball Hyperdynamic: EF >75% Normal: EF 55-65% Moderately Reduced: EF 30-55% Severely Reduced: EF <30%

53 Hyperdynamic Normal

54 Hyperdynamic Normal

55 Normal Moderately Decreased

56 Normal Moderately Decreased

57 Moderately Depressed Severely Depressed

58 Fractional Shortening Fractional Shortening : Normal 25-45% FS = (EDV-ESV) / EDV

59 Ways to measure LV EF Simpson s Method - Method of Discs

60 EPSS History: EPSS EPSS correlated with angio 125 patients: Strong negative correlation r = EPSS absent or <5mm in most normal hearts

61 EPSS E-Point Septal Separation: Ahmadpour H et al. Mitral E point septal separation: a reliable index of left ventricular performance in coronary artery disease. Am Heart J Jul; 106: in 108 patients EPSS > 7mm 87% sen, 75% spec for EF<50%

62 EPSS: Novice v Expert 12 PGY3s&4s perform EPSS on patients with dyspnea Correlated EPSS with EM US director and cardiologist visual estimation

63 EPSS: Novice v Expert 12 PGY3s&4s perform EPSS on patients with dyspnea Correlated EPSS with EM US director and cardiologist visual estimation

64 EPSS v MRI Quantitative Estimation of Left Ventricular Ejection Fraction from Mitral Valve E-Point Septal Separation and Comparison to Magnetic Resonance Imaging. Silverstein J et al. Am J Cardiol EPSS measured on MRI and compared to MRI Ejection Fraction MRI LVEF = MRI EPSS with r=0.82

65 EPSS v MRI

66 PSLA RVOT Ao LV LA

67 PSLA RVOT Ao LV LA

68 PSLA

69 PSLA

70 PSLA

71

72

73

74

75

76

77

78

79

80

81 E

82 E

83 E A

84

85

86

87

88 Pitfalls Aortic Insufficiency Mitral Stenosis Mitral Calcifications

89 Aortic Insufficiency Pitfalls

90 Mitral Stenosis Pitfalls

91 Mitral Calcification Pitfalls

92 Mitral Calcification Pitfalls

93 Summary CO may be useful when evaluating fluid responsiveness. May only need the VTI. Eyeball and EPSS are excellent ways of assessing cardiac function and EF.

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