( 12 17mLO 2 /dl) 1.39 Hb S v O P v O2

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1 Harold James Swan William Ganz N Engl J Med 1) 40 (mixed venous oxygen saturation S v O2 ) (central venous oxygen saturation Scv O2 ) (Hb) S v O2 Scv O Ganz 2) 20 Forrester Swan Forrester subset 3 5) Forrester subset S v O2 S v O2 (Sa O2 ) ( V O2 /ḊO 2 ) S v O2 arterial O 2 content (Ca O2 ) 1.39 Hb Sa O Pa O2 mixedvenous O 2 content (C v O2 ) (16 22mLO 2 /dl) (12 17mLO 2 /dl) 1.39 Hb S v O P v O2 O 2 consumption index ( V O2 I) ( mL/min/m 2 ) (Ca O2 C v O2 ) CI 10 oxygen delivery index(d O2 I) ( mL/min/m 2 ) Ca O2 CI 10 oxygen extraction(oxygen utilization) ( ) V O2 /ḊO 2 = (Ca O2 C v O2 )/Ca O2 mixed venous oxygen saturation (S v O2 ) (68 77 ) S v O2 = Sa O2 (1 V O2 /ḊO 2 )

2 Hb S v O2 S v O Rouby 6) 3 S v O Scuderi 7) 2 3 S v O2 Hb Sa O2 Hb Sa O2 S v O2 S v O2 Gattinoni 8) 56 (intensive care unit: ICU) S v O2 30 Richard 9) 36 ICU Yu 10) ,010 ICU 2 11) Richard 9) ESCAPE Study (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness study) 12) 4 Sandham 13) 0.9 ICU 1 Forrester subset Scv O2 Scv O2

3 34 Scv O Scheinman 14) Scv O Rivers N Eng J Med early goaldirected therapy(egdt) 15) EGDT surviving sepsis campaign guidelines ) EGDT 65 mmhg 0.5 ml/kg/ 8 12 mmhg Scv O Scv O2 S v O2 Dueck 17) Scv O2 Scv O2 S v O2 Dueck 17) Scv O2 S v O2 8 Scv O2 S v O ) 2. (mixed venous oxygen saturation S v O2 ) S v O2 ( 18 ) S v O2 Scv O Krafft 18) ( ) Scv O2 70 EGDT 15,16)

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