Subclavian and Axillary Artery Aneurysms

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1 Subclavian and Axillary Artery Aneurysms April 2008 Francesco A Aiello, M.D. Assistant Professor of Surgery Division of Vascular Endovascular Surgery University of Massachusetts Medical School

2 None DISCLOSURES

3 CASE PRESENTATION 87 yo male awoken at 2am with abrupt onset of Right arm pain and numbness Tried to sleep it off after taking advil Increased pain and some motor loss of hand Presented to outside hospital with A-fib in ambulance ride Quickly transferred to University of Massachusetts for evaluation.

4 Past Medical Hx : Benign prostatic hyperplasia Hypertension Hypothyroidism Gout Past Surgical Hx: Bilateral Total Knee replacements Social: Quit smoking 30 years ago Lives independently and uses stationary bike CASE PRESENTATION Physical Exam: Normal Sinus Rythym Decreased sensation in all digits with minimal weakness Palpable mass in Right Axilla: Non-pulsatile No palpable pulses in Right arm or hand Weak monophasic palmer arch

5 OR Brachial artery exposure Embolectomy of brachial and axillary artery Fresh thrombus proximal and distal Difficult passing catheter proximally Continues thrombus

6

7 BY THE WAY Oh, I completely forgot. I had breast cancer and they did a surgery with radiation to my chest I think both sides

8 CASE

9

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12 AXILLARY AND SUBCLAVIAN ARTERY ANEURYSMS Very rare peripheral artery aneurysms Make up % of all peripheral aneurysms Subclavian more common than axillary Right vs. Left Associated with multiple signs and symptoms Embolization Increased incidence over the last few decades Fewer symptomatic Dent et al. Arch Surg 1972 Pairolero et al. Surgery 1981 Hobson et al. Vito JST (eds) 1982

13 SUBCLAVIAN ARTERY ANEURYSM Then: Mycotic, Syphilitic, Tuberculotic NOW: Arterial Thoracic Outlet Syndrome Degenerative Pseudoaneurysm Traumatic Collagen Disorders Lazar B. Davidovic et al. Asian J Surg 2003

14 SUBCLAVIAN ARTERY ANEURYSM Proximal Atherosclerosis Collagen Trauma Middle Collagen Trauma Infection Distal TOS B.P. Vierhout et al. Eur J Vasc Endovasc Surg 2010

15 AXILLARY ARTERY ANEURYSM Extemely Rare Younger & Athletic...and the not so Athletic Crutch Induced Anatomy Tethering

16 PRESENTATION Most are Symptomatic Pain Chest, Neck, Shoulder Pulsating Mass Embolism Thrombosis Brachial Plexus Neuralgia Other Rupture, Hoarseness, Transient ischemic attack or Stroke, Horner syndrome, Dysphagia, Hemoptysis, venous congestion

17 Physical Exam DIAGNOSIS Pulsatile mass depending on location Imaging Studies Angiography CTA MRI/A US Esteves FP et al. J Vasc Bras 2013

18 WHEN TO TREAT? No definitive size criteria Size doesn t matter or does it? Natural History remains a mystery Recommend repair of all aneurysms

19 OPEN SURGICAL TREATMENT Supraclavicular Approach Infraclavicular Approach Median Sternotomy Left Thoracotomy Along Vessel Course Combination of Above Irradiated Field Complications, Complications, Complications Nerve injury Ischemia Stroke Pulmonary Infection/Abscess Mortality3-21% Salo et al. Eur J Vasc Surg 1990

20 ENDOVASCULAR TREATMENT Complication rates Access Manipulation SUCCESS?? How is Success Measured? Early success=>95% Long-term success? Patency Reintervention Beregi et al. Cardiovasc Intervent Radiol 1999 Schoder et al. J Endovasc Ther 2003 Esteves et al. Cardiovasc Intervent Radiol 1999

21 Marin et al. J Vasc Surg 1994 Sullivan et al. J Endovasc Surg 1996 Ewings et al. Vasc Endovasc Surg 2008 Iida et al. Ann Thorac Cardiovasc Surg 2011 ENDOVASCULAR TREATMENT: NO Instruction For Use WHY THE CONFUSION? NO Industry or Institution Guidelines NO Large Prospective Studies NO Large Retrospective Studies NO FDA approved stent grafts for Upper extremity aneurysm NO Consistency in Stent Graft Utilization Dacron, PTFE, Silicone, and Vein

22 ENDOVASCULAR TREATMENT CONSIDERATIONS Pre-operative planning Access Initial reports, lots of complications Manipulation Anticoagulate immediately Seal zones 5mm-1cm Size discrepancy High variance in different segments Collateral Flow Importance and effects of covering? Adjunct Procedures Vertebral re-implantion? Operative Field Increased risk of graft infection? Location, location, location Stent failure? Ewings et al. Vasc Endovasc Surg 2008 Iida et al. Ann Thorac Cardiovasc Surg 2011 Park et al. Interactive CardioVasc &Thoracic Surgery 2015

23 Subclavian and Axillary Artery Aneurysms April 2008 Francesco A Aiello, M.D. Assistant Professor of Surgery Division of Vascular Endovascular Surgery University of Massachusetts Medical School

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