Basic and translational research in motility and neurogastroenterology

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1 Basic Science Course Basic and translational research in motility and neurogastroenterology June 27 29, 2018 Gasthuisberg Health Sciences Campus, Leuven, Belgium Programme

2 Course directors Jan Tack, Belgium Tim Vanuytsel, Belgium Ricard Farré, Belgium Gianluca Matteoli, Belgium Faculty Guy Boeckxstaens, Belgium Florencia Carbone, Belgium Maura Corsetti, United Kingdom Inge Depoortere, Belgium Ans Pauwels, Belgium Magnus Simren, Sweden Vassilia Theodorou, France Pieter Vanden Berghe, Belgium Lukas Van Oudenhove, Belgium WEDNESDAY, June 27, 2018 Registration 10:00 10:50 Main entrance hall O&N 1 All lectures on Wednesday in Auditorium Pentalfa Introduction 10:50 11:00 Welcome and opening Jan Tack 11:00 11:30 Functional and motility disorders of the gastrointestinal tract: clinical and research challenges Magnus Simren Tutors Alison Accarie, Belgium Javier Aguilera, Belgium Dorien Beeckmans, Belgium Jessica Biesiekierski, Australia Werend Boesmans, Belgium Carla Cirillo, Belgium Veronica De Simone, Belgium Hannelore Geysen, Belgium Nick Goelen, Belgium Sales Ibiza, Belgium Julie Iven, Belgium Pieter Janssen, Belgium Danielle Jongen, Belgium Imke Masuy, Belgium Linda Nys, Belgium Jasper Pannemans, Belgium Eluisa Perna, Belgium Nathalie Rommel, Belgium Nathalie Stakenborg, Belgium Theo Thijs, Belgium Joran Toth, Belgium Karen Van den Houte, Belgium Wout Verbeure, Belgium Lucas Wauters, Belgium Nathalie Weltens, Belgium Motility disorders and motility measurements 11:30 12:00 Assessment of gastrointestinal motility in humans Maura Corsetti 12:00 12:30 Assessment of gastrointestinal motility in animals in vitro and in vivo; animal models of altered motility Ricard Farré 12:30 13:00 Neural control of motility in animals and humans Pieter Vanden Berghe

3 13:00 14:00 Lunch break Control of food intake 14:00 14:30 Control of hunger, nutrient tolerance and food intake in animals and humans Inge Depoortere Mucosal integrity, stress, luminal factors and low-grade inflammation 14:30 15:00 Assessment of mucosal integrity, stress responses, luminal responses and low-grade inflammation in humans Tim Vanuytsel 15:00 15:30 Assessment of mucosal integrity, stress responses, luminal responses and low-grade inflammation in vitro and in animal models. Ricard Farré, Gianluca Matteoli Visceral hypersensitivity 16:00 16:30 Assessment of visceral sensitivity in humans; visceral hypersensitivity disorders Ans Pauwels 16:30 17:00 Assessment of visceral sensitivity in animals; animal models of visceral hypersensitivity Vassilia Theodorou 17:00 17:30 Use of brain imaging to assess visceral sensitivity and food reward Lukas Van Oudenhove Wrap-up and end of the day 17:30 18:00 Practical arrangements for the next day 19:30 Dinner 15:30 16:00 Coffee break

4 THURSDAY, June 28, 2018 Parallel lectures: How to organise motility studies 08:30 09:00 How to set up basic neurogastroenterology and motility studies: choice of animal models and access to human samples Ricard Farré, Gianluca Matteoli O&N1 Vesalius (ALO ) How to set up neurogastroenterology and motility studies in healthy subjects Florencia Carbone, Ans Pauwels O&N1 Vesalius (ALO ) Parallel Demonstrations & Hands-on sessions 09:00 15:30 Interrupted for coffee and lunch 10:30 10:45 Coffee break 12:30 14:00 Lunch break Block 1: TARGID Animal gastric emptying Inge Depoortere, Linda Nys Motility in organ bath, Muscle strip contractility Ricard Farré, Theo Thijs Mucosal integrity studies Ricard Farré, Joran Toth Mucosal immunology techniques Sales Ibiza, Veronica De Simone Block 2: TARGID Animal visceral sensitivity testing, afferent nerve recording Javier Aguilera, Eluisa Perna Stress protocols in animals Alison Accarie, Lucas Wauters Vagus nerve stimulation Nathalie Stakenborg Neural imaging in cultures and in human tissues Werend Boesmans, Carla Cirillo Block 3: MOTILITY UNIT Multimodal sensitivity testing Ans Pauwels, Hannelore Geysen Esophageal motility studies Ans Pauwels, Hannelore Geysen, Nathalie Rommel Block 4: MOTILITY UNIT Small bowel manometry, hormone levels Wout Verbeure, Imke Masuy Colonic manometry Jasper Pannemans Block 5: ACRONIM / TARGID Intragastric pressure/gastric barostat Florencia Carbone, Karen Van den Houte Gastric balloon manometry Pieter Janssen, Nick Goelen Human biopsies and luminal aspiration Dorien Beeckmans

5 Block 6: ACRONIM Nutrient tolerance studies Jessica Biesiekierski, Julie Iven Brain imaging Julie Iven, Danielle Jongen, Nathalie Weltens 15:30 16:00 Coffee break Presentation of 5 selected abstracts 16:00 17:00 18:30 Dinner FRIDAY, June 29, 2018 Parallel lectures: How to build a career in neurogastroenterology and motiltiy 08:30 09:00 How to build a career in basic research in neurogastroenterology and motility Guy Boeckxstaens, Gianluca Matteoli O&N1 Vesalius (ALO ) How to build a career in clinical research in neurogastroenterology and motility Jan Tack, Tim Vanuytsel O&N1 Vesalius (ALO ) E-learning...and many more! Faecal Microbiota Transplantation Malignant Liver Lesions Online Courses Standards and Guidelines Search over 30,000 items (incl. abstracts, posters, recordings and guidelines) The universal online source of knowledge in gastroenterology! Library Latest News Parallel Demonstrations & Hands-on sessions 09:00 15:30 Interrupted for coffee and lunch 10:30 10:45 Coffee break 12:30 14:00 Lunch break Block 1: TARGID Animal gastric emptying Inge Depoortere, Linda Nys Motility in organ bath, Muscle strip contractility Ricard Farré, Theo Thijs Mucosal integrity studies Ricard Farré, Joran Toth Mucosal immunology techniques Sales Ibiza, Veronica De Simone Colorectal Polyps Liver Biopsy Blogs Mistakes in Decide on the Spot Find out more, visit

6 Block 2: TARGID Animal visceral sensitivity testing, afferent nerve recording Javier Aguilera, Eluisa Perna Stress protocols in animals Alison Accarie, Lucas Wauters Vagus nerve stimulation Nathalie Stakenborg Neural imaging in cultures and in human tissues Werend Boesmans, Carla Cirillo Block 6: ACRONIM Nutrient tolerance studies Jessica Biesiekierski, Julie Iven Brain imaging Julie Iven, Danielle Jongen, Nathalie Weltens Closure and farewell with coffee 15:30 16:00 Main entrance hall O&N 1 Block 3: MOTILITY UNIT Multimodal sensitivity testing Ans Pauwels, Hannelore Geysen Esophageal motility studies Ans Pauwels, Hannelore Geysen, Nathalie Rommel Block 4: MOTILITY UNIT Small bowel manometry, hormone levels Wout Verbeure, Imke Masuy Colonic manometry Jasper Pannemans Block 5: ACRONIM / TARGID Intragastric pressure/gastric barostat Florencia Carbone, Karen Van den Houte Gastric balloon manometry Pieter Janssen, Nick Goelen Human biopsies and luminal aspiration Dorien Beeckmans Where Basic Science meets Gastroenterology Translational/Basic Science symposia UEG Journal publication Visiting Fellowship Programme Basic Science Course Rising Star Award UEG Committee membership Young Investigators Meeting Find out more, visit Today s Science; Tomorrow s Medicine symposia Networking & exchange Horizon 2020 Session at UEG Week UEG Education online Research Prize Awards & Grants for abstract submitters

7 Organiser United European Gastroenterology GmbH House of European Gastroenterology Wickenburggasse 1 A-1080 Vienna, Austria T F office@ueg.eu The UEG Basic Science Course, Leuven, Belgium, 27/06/ /06/2018 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME ) with 20 European CME credits (ECMEC s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

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