N -Acetylneuraminic Acid 1, 39 * * * N -Acetylneuraminic Acid Methyl Ester. N -Acetylserotonin 48 * Chemical Name Structural Formula Page.

Transcription

1 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super Acetic Acid * -Acetyl-,-didehydro-- deoxyneuraminic Acid 9 * -Acetylneuraminic Acid, 9 * * * -Acetylneuraminic Acid Methyl Ester 9 * -Acetylserotonin 48 * Adenosine Diphosphate (ADP) 4, 5, 49 * * * Adenosine Monophosphate (AMP) 4, 5, 6, 49 * * * A Adenosine Triphosphate (ATP) 4, 5, 49 * * * Adrenaline 8 * * * Alanine 9 * Allantoin 0 * * Alprenolol,, * * * -Aminobutyric Acid (GABA) 4 * * * 4-(Aminomethyl)benzoic Acid 4 * Arginine 9 * / 8

2 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super A L-Ascorbic Acid (Vitamin C),, 4, 5 * * * Aspartic Acid 9 * Benzene 5, 6, 7 * * * Benzenesulfonic Acid 5, 6, 7 * * * Benzoic Acid 40, 5 * B Benzonitrile 8 * * * Bis[(trifluoromethyl)sulfonyl] amine Anion (CF S ) - 7 * Buformin 8 * -Butyl--methylimidazolium Chloride 4 * Caffeine 9 * * * Chlorpromazine * C Citric Acid * Clomipramine * Creatine 4 * Creatinine 8 * * * / 8

3 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super 4-Cyanobenzoic Acid 4 * C Cyclic Adenosine Monophosphate (camp) 4, 49 * * * Cytidine Monophosphate (CMP) 6, 7 * * * Dehydroacetic Acid 5 * Dichloroacetic Acid 0 * Dicyanamide Anion (C) - 6 * D,5-Dihydroxybenzoic Acid 8 * * *,5-Diiodo-L-thyronine 50 *, -Dimethylsulfamide 5 * S H DPA 8 * * * Dopamine 8,8 * * * Erythorbic Acid 4 * * * E Ethylbenzene 5, 6, 7 * * * 4-Ethylbenzene sulfonic Acid 5, 6, 7 * * * -Ethyl-4-methylimidazole * / 8

4 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super E -Ethyl--methylimidazolium 6, 7 * F Fumaric Acid 45 * GABA See Page. " -Aminobutyric Acid" 4 Galacturonic Acid, * * * --α-d-glucopyranosyl- L-ascorbic Acid 4 * * * Glucose -Phosphate 47 * D-Glucose 6-Phosphate 47 * G L-Glutamic Acid 4 * * * Glutathione oxidized form (GSSG) 44 * Glutathione reduced form (GSH) 44 * -Glycolylneuramic Acid, 9 * * * Glyphosate * * * Guanosine Monophosphate (GMP) 6 * * H Hexafluorophosphate PF 6-7 * 4 / 8

5 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super Histamine, 4 * * Homovanillic Acid (HVA) 8 * * * H -Hydrazinobenzoic Acid 40 * 4-Hydrazinobenzoic Acid 40 * 5-Hydroxyindole--acetic Acid 48 * 5-Hydroxy-L-tryptophan 5, 48 * * * Inosine Monophosphate (IMP) 6 * * I Isobutyl 4-Hydroxybenzoate 7 * Isoproterenol 8 * * * Lactic Acid * L Levulinic Acid 8 * Lithium Chloride LiCl * Maleic Acid 45 * M Malic Acid, 45 * Melamine 9 * * * Melatonin 48 * 5 / 8

6 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super Metformin 6, 7, 8 * * * Methionine 9 * * Methyl Levulinate 8 * M 4-Methyl-H -benzotriazole 46 * 5-Methyl-H -benzotriazole 46 * -Methylimidazole * Monochloroacetic Acid 0 * AD+ (icotinamide Adenine Dinucleotide) 0 * * icardipine,, * * * icotinic Acid 0 * * oradrenaline 8 * * * D-Panthenol 0 * * P Phenformin 8 * -Phenoxyethanol 5 * 6 / 8

7 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super Phenylalanine 9 * L-Phenylephrine 9 * * * P Phosphocreatine 4 * Potassium Bromide KBr, 5 * Potassium Chloride KCl, * * Potassium Iodide Kl, 5 * Serotonin (5-HT) 8, 48 * * S Sodium Chloride acl * Sorbic Acid 5 * Succinic Acid 45 * Tartaric Acid 45 * Tetrafluoroborate Anion BF 4-6 * T DL-Thyronine 50 * L-Thyroxine (T4) 50 * Toluene 5, 6, 7 * * p -Toluenesulfonic Acid 5, 6, 7 * * * 7 / 8

8 Chemical ame Structural Formula Page. Cation-Exchange DS- CX0 DS- CX5 DS- CX0 Anion-Exchange DS- AX0 DS- AX0 DS- SAX Super Toluidine (o,m,p ) * * * Tranexamic Acid 4 * Trichloroacetic Acid 0 * T Trifluoromethanesulfonate CF S - (Trifluoromethyl)trifluoroborate Anion CF BF - 6 * 6, 7 *,',5-Triiodo-L-thyronine (T) 50 * L-Tryptophan 48 * Tyramine 8 * * * U Uridine Monophosphate (UMP) 6,7 * * * Vanillylmandelic Acid (VMA) 8 * * * V Verapamil,, * * * Vitamin C See Page. "L-Ascorbic Acid",, 4, 5 8 / 8

9 Sialic Acids : Kaseisorb LC DS-SAX Super : TCI Dual DS-AX0 : TCI Dual DS-AX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 5.0, CH CH) = 5 / 95 UV 0 nm.0 ml/min Temperature 0 C. -Glycolylneuramic acid. -Acetylneuramic acid H HH C H H H H CH H H H H H CH H H --

10 rganic Acids : Galacturonic Acid : Ascorbic Acid : Lactic Acid : Acetic Acid : Malic Acid : Citric Acid min TCI Dual DS-AX0 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph7.0, H P 4 ) = 0 / 80 UV 0 nm.0 ml/min Galacturonic Acid -Ascorbic Acid (Vitamin C) Lactic Acid H CH H H H H H H H H H Acetic Acid Malic Acid Citric Acid H H H H H H H H --

11 rganic Acids : Kaseisorb LC DS-SAX Super : TCI Dual DS-AX0 : TCI Dual DS-AX0, : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph7.0, H P 4 ) = 0 / 90 UV 0 nm.0 ml/min. Galacturonic Acid. -Ascorbic Acid (Vitamin C) H CH H H H H H H H --

12 Adenosine Phosphates 4 : Kaseisorb LC DS-SAX Super : TCI Dual DS-AX0 4 : TCI Dual DS-AX0 4 4, : Kaseisorb LC DS min Mobile Phase 4.6 mmi.d. X 50 mm A : CH H / 0 mmol/l K HP 4 (ph 7.0, H P 4 ) = 0 / 80 B : CH H / 50 mmol/l K HP 4 (ph 7.0, H P 4 ) = 0 / % B (0-0 min) UV 54 nm.0 ml/min. AMP. ADP H P H H P P H H H H H H H H. camp 4. ATP P H H H P P P H H H H H H H -4-

13 ucleotides (Adenosine Phosphates) : Kaseisorb LC DS-SAX Super ADP and ATP is not elution. : TCI Dual DS-AX0 : TCI Dual DS-AX0,, : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l H 4 HC (ph 7.8) = 0 / 80 UV 54 nm.0 ml/min. AMP H. ADP H H P H H H H P H P H H H. ATP H H P H P H P H H H -5-

14 ucleotides,4 5 : TCI Dual DS-AX (min) 4 5 : TCI Dual DS-AX (min) 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph 7.0,H P 4 ) = 0 / 80 UV 54 nm.0 ml/min H. CMP. UMP. IMP H H P H P H H H H 4. GMP 5. AMP H H H H P H H H H H P H H H H H H P H H H -6-

15 ucleotides : Kaseisorb LC DS-SAX Super, : TCI Dual DS-AX0 : TCI Dual DS-AX0, : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph 7.0, H P 4 ) = 0 / 90 UV 54 nm.0 ml/min. CMP (Cytidine Monophosphate). UMP (Uridine Monophosphate) H H H P H H P H H H H H -7-

16 Catecholamines,4,5,7 8,9,0 : TCI Dual DS-CX : TCI Dual DS-CX : TCI Dual DS-CX min 4.6 mmi.d. 50 mm Mobile Phase CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 70 / 0 UV 54 nm.0 ml/min Temperature 5. VMA. DPA. HVA 4. oradrenaline 5. Adrenaline H H H H H H H H H H H H H H H H H 6. Creatinine 7. Dopamine 8. Serotonin 9. Tyramine 0. Isoproterenol H H H H H H H H H H H H H H -8-

17 Amino Acids : Aspartic Acid : Alanine : Methionine : Phenylalanine : Arginine min Mobile Phase TCI Dual DS-CX5 4.6 mmi.d. X 50 mm A: CH C / 5 mmol/l KH P 4 (ph.0, H P 4 ) = 5 / 95 B: CH C / 50 mmol/l KH P 4 (ph.0, H P 4 ) = 40 / % B (5-0 min) UV 0 nm.0 ml/min Temperature 0 C Aspartic Acid Alanine Methionine H S H H H H H H Phenylalanine Arginine H H H H H H H -9-

18 Allantoin, D-Panthenol : TCI Dual DS-CX (min) : TCI Dual DS-CX (min) 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph 6.0, H P 4 ) = 0 / 90 UV 0 nm.0 ml/min Temperature 0 C. Allantoin. D-Panthenol H H H H H H H -0-

19 Basic Drugs : TCI Dual DS-CX0 : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph.5, CH CH) = 80 / 0 UV 54 nm.0 ml/min. icardipine. Verapamil. Alprenolol H H --

20 Basic Drugs min TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 80 / 0 UV 0 nm.0 ml/min. icardipine. Verapamil. Alprenolol H H --

21 Basic Drugs min TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C/ 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 80 / 0 UV 0 nm.0 ml/min. icardipine. Verapamil. Alprenolol 4. Clomipramine 5. Chlorpromazine H H Cl Cl S --

22 L-Glutamic Acid, GABA : TCI Dual DS-CX0 : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / H / H P 4 = 5 / 95 / 0. UV 0 nm.0 ml/min Temperature 5. L-Glutamic Acid. GABA ( -Aminobutyric Acid) H H H H H -4-

23 Sulfonic Acids,6 4 5 Mobile Phase : CH C / 50 mmol/l K HP 4 (ph 7.0, H P 4 ) = 50 / Mobile Phase : CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / Mobile Phase : CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 50 / min TCI Dual DS-AX0 4.6 mmi.d. X 50 mm UV 54 nm.0 ml/min Temperature 0. Benzene. Toluene. Ethylbenzene 4. Benzenesulfonic Acid 5. p-toluenesulfonic Acid 6. 4-Ethylbenzenesulfonic Acid S H S H S H -5-

24 Sulfonic Acids 4 5 Mobile Phase : CH C / 50 mmol/l K HP 4 (ph 7.0, H P 4 ) = 50 / Mobile Phase : CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / Mobile Phase : CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 50 / min TCI Dual DS-AX0 4.6 mmi.d. X 50 mm UV 54 nm.0 ml/min Temperature 0. Benzene. Toluene. Ethylbenzene 4. Benzenesulfonic Acid 5. p-toluenesulfonic Acid 6. 4-Ethylbenzenesulfonic Acid S H S H S H -6-

25 Sulfonic Acids Mobile Phase : CH C / 50 mmol/l K HP 4 (ph 7.0, H P 4 ) = 50 / 50 4 Mobile Phase : CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / Mobile Phase : CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 50 / min Kaseisorb LC DS-SAX Super 4.6 mmi.d. X 50 mm UV 54 nm.0 ml/min Temperature 0. Benzene. Toluene. Ethylbenzene 4. Benzenesulfonic Acid 5. p-toluenesulfonic Acid 6. 4-Ethylbenzenesulfonic Acid S H S H S H -7-

26 : TCI Dual DS-AX0 : TCI Dual DS-AX0 : Kaseisorb LC DS-SAX Super min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mol/l CH CH 4 (ph 4.5, CH CH) = 40 / 60 UV 0 nm.0 ml/min Temperature 0 C. Dopamine. Benzonitrile.,5-Dihydroxybenzoic Acid H H C C H H H H -8-

27 : TCI Dual DS-CX0 L-Phenylephrine is not elution. : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / H / TFA = 0 / 80 / 0.05 UV 54 nm.0 ml/min. Caffeine. L-Phenylephrine H H H H -9-

28 Halogenated Acetic Acids 70 mau min Kaseisorb LC DS-SAX Super 4.6 mmi.d. X 50 mm Mobile Phase CH C / 5 mmol/l HCH 4 (ph.5, HCH) = 50 / 50 UV 0 nm.0 ml/min Temperature 0 C. Monochloroacetic Acid. Dichloroacetic Acid. Trichloroacetic Acid Cl H Cl Cl H Cl Cl Cl H -0-

29 Imidazoles mau min TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l K HP 4 (ph 7.0, H P 4 ) = 0 / 80 UV 0 nm.0 ml/min. -Methylimidazole H. -Ethyl-4-methylimidazole H --

30 Herbicide : Kaseisorb LC DS-SAX Super : TCI Dual DS-AX0 : TCI Dual DS-AX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH H / 5 mmol/l KH P 4 (ph.0, H P 4 ) = 0 / 80 UV 0 nm.0 ml/min Glyphosate H H P H H --

31 Histamine TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 00 mmol/l CH CH 4 = 50 / 50 UV 0 nm.0 ml/min Temperature 5 C Histamine H H --

32 Histamine TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 00 mmol/l CH CH 4 = 50 / 50 UV 0 nm.0 ml/min Temperature 5 C Histamine H H -4-

33 5-Hydroxy-L-tryptophan : TCI Dual DS-CX0 : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 0 / 90 UV 54 nm.0 ml/min Temperature 5 C 5-Hydroxy-L-tryptophan -5-

34 Metformin : TCI Dual DS-CX0 : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l KH P 4 (ph.0, H P 4 ) = 50 / 50 UV 5 nm.0 ml/min Metformin H H H H -6-

35 Metformin and Isobutyl 4-Hydroxybenzoate Mobile Phase : CH C / 50 mmol/l KH P 4 (ph.0, H P 4 ) = 50 / 50 Mobile Phase : CH C / 50 mmol/l HCH 4 (ph.0, HCH) = 50 / min TCI Dual DS-CX5 4.6 mmi.d. X 50 mm UV 5 nm.0 ml/min. Isobutyl 4-Hydroxybenzoate. Metformin H H H H H -7-

36 Levulinic Acid, Methyl Levulinate mv min TCI Dual DS-AX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l K HP 4 (ph 7.0, H P 4 ) = 0 / 80 UV 0 nm.0 ml/min Temperature 5 C. Levulinic Acid. Methyl Levulinate H -8-

37 Melamine : TCI Dual DS-CX0 : TCI Dual DS-CX5 : TCI Dual DS-CX0 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l KH P 4 (ph.0, H P 4 ) = 40 / 60 UV 0 nm.0 ml/min Temperature 5 C Melamine H H H -9-

38 icotinic Acid and Derivatives : Kaseisorb LC DS-SAX Super : TCI Dual DS-AX min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 0 / 90 UV 54 nm.0 ml/min Temperature 0 C. AD+. icotinic Acid - P H + H H H H P - H H -0-

39 Toluidines A) TCI Dual DS-CX0 B) TCI Dual DS-CX5 C) TCI Dual DS-CX min A) TCI Dual DS-CX0 B) TCI Dual DS-CX5 C) TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l HCH 4 (ph.4, HCH) = 50 / 50 UV 54 nm.0 ml/min Temperature 5 C. o-toluidine. m-toluidine. p-toluidine H H H --

40 Halide Ions : Corona CAD min 4 : UV 0 nm min Kaseisorb LC DS-SAX Super 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / 50 Corona CAD (Range: 00 pa, Filter: High, ebulizer: 5 C), UV 0 nm.0 ml/min. K +. Cl -. Br - 4. I - --

41 Alkali Halides min TCI Dual DS-CX5 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / 50 Corona CAD (Range : 00 pa, Filter: High, ebulizer: 5 C).0 ml/min. Cl -. Li +. a + 4. K + --

42 Ionic liquid Cl min TCI Dual DS-CX0 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 0 / 90 Corona CAD (Range: 00 pa, Filter: Corona, ebulizer: 5 C).0 ml/min -Butyl--methylimidazolium chloride + Cl - -4-

43 Halide Ions min Kaseisorb LC DS-SAX Super 4.6 mmi.d. X 50 mm Mobile Phase CH C / 50 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / 50 UV 0 nm.0 ml/min. Br -. I - -5-

44 -Ethyl--methylimidazolium salts + (C) BF 4 - CF BF - CF S min Colum Size Kaseisorb LC DS-SAX Super (5μm) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 00 mmol/l CH CH 4 (ph 5.0, CH CH) = 50 / 50 Corona CAD.0 ml/min -Ethyl--methylimidazolium + (C) - BF CF BF - CF S -6-

45 -Ethyl--methylimidazolium salts + CF BF (CF S ) - PF min Kaseisorb LC DS-SAX Super (5 m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 00 mmol/l CH CH 4 (ph 5.0, CH CH) = 75 / 5 Corona CAD.0 ml/min -Ethyl--methylimidazolium + CF BF - (CF S ) - PF

46 Antidiabetic Drugs min TCI Dual DS-CX5 (5 m) 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l CH CH 4 (ph 6.78) = 70 / 0 UV 0 nm.0 ml/min. Metformin. Buformin H H H H H H H H H. Phenformin H H H H H Size.0 L (.0 mg/ml) -8-

47 Sialic Acids 4 : TCI Dual DS-AX0 (5μm),,4 : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 5.0, CH CH) = 5 / 95 UV 0 nm.0 ml/min Temperature 0 C. -Acetylneuraminic Acid Methyl Ester. -Glycolylneuramic Acid. -Acetylneuraminic Acid Hydrate 4. -Acetyl-,-didehydro--deoxyneuraminic Acid -9-

48 Hydrazinobenzoic Acids : TCI Dual DS-AX0 (5 m), : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/ch CH 4 (ph 5.0,CH CH) = 0 / 80 UV 54 nm.0 ml/min. 4-Hydrazinobenzoic Acid. -Hydrazinobenzoic Acid. Benzoic Acid -40-

49 L-Ascorbic Acid related compounds : TCI Dual DS-AX0 (5 m) : TCI Dual DS-AX0 (5 m) : Kaseisorb LC DS SAX Super (5 m), : Kaseisorb LC DS min 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 5.0, CH CH) = 0 / 90 UV 54 nm.0 ml/min. --α-d-glucopyranosyl- L-ascorbic Acid. L-Ascorbic Acid. Erythorbic Acid H H H H -4-

50 Tranexamic Acid related compounds min TCI Dual DS-CX5 (5 m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 5 mmol/l HCH 4 (ph.5, HCH) = 0 / 80 UV 0 nm.0 ml/min Temperature 5 C. 4-Cyanobenzoic Acid (0.0mg/.0mL). 4-(Aminomethyl)benzoic Acid (0.0mg/.0mL). Tranexamic Acid (.0mg/.0mL) Size.0 L -4-

51 Creatine related compounds min Kaseisorb LC DS-SAX Super (5 m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 5.0, CH CH) = 0 / 90 UV 0 nm.0 ml/min. Creatine. Phosphocreatine Size.0 L (0mg/mL) -4-

52 Glutathiones min TCI Dual DS-AX0 (5 m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 6.8, CH CH) = 0 / 70 UV 0 nm.0 ml/min. Glutathione reduced form (GSH). Glutathione oxidized form (GSSG) -44-

53 rganic Acids (Dicarboxylic acids) min TCI Dual DS-AX0 ( m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0mmol/L KH P 4 (ph 7.0, H P 4 ) = 0 / 80 UV 0 nm.0 ml/min. Tartaric Acid. L-Malic Acid. Succinic Acid 4. Fumaric Acid 5. Maleic Acid -45-

54 Anti-corrosion agent Methyl-H-benzotriazole(mixture) 5-Methyl-H-benzotriazole min TCI Dual DS-CX5 ( m) 4.6 mmi.d. X 50 mm Mobile Phase CH C / 0 mmol/l CH CH 4 (ph 5.0, CH CH) = 0 / 90 UV 0 nm.0 ml/min Temperature 0 C. 4-Methyl-H-benzotriazole. 5-Methyl-H-benzotriazole Size.0 L(.0mg/mL mobile phase) -46-

55 Sugar Phosphate min TCI Dual DS-AX0 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l K HP 4 (ph 6.9, H P 4 ) = 5 / 95 RI.0 ml/min. D-Glucose 6-Phosphate. Glucose -Phosphate H H H H - P

56 Serotonin and Metabolites min Mobile Phase TCI Dual DS-CX0 4.6 mmi.d. X 50 mm A: CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 0 / 90 B: CH C / 50 mmol/l HCH 4 (ph.5, HCH) = 70 / 0 A to 00 % B in 60 min UV 54 nm.0 ml/min Temperature 5 C. 5-Hydroxy-L-tryptophan. 5-Hydroxyindole--acetic Acid.-Acetylserotonin H H H H H H 4. L-Tryptophan 5. Serotonin 6. Melatonin H H H H H H -48-

57 Adenosine Phosphates min Mobile Phase TCI Dual DS-AX0 4.6 mmi.d. X 50 mm A : CH C / 0 mmol/l H 4 HC (ph 7.8) = 0 / 90 B : CH C / 0 mmol/l H 4 HC (ph 7.8) = 0 / 70 0 %B(0- min), 0-00 % B (- min), 00 %B(-0 min) UV 54 nm.0 ml/min H. camp. AMP H P P H H H H H H. ADP H 4. ATP H H P H P H H H H P H P H P H H H -49-

58 Thyroid hormones min Mobile Phase TCI Dual DS-CX5 (5μm) 4.6 mmi.d. X 50 mm A:CH C B:0 mmol/l HCH 4 (ph.0, HCH) 80-40%B (0-8min), 40%B (8-5min) UV 54 nm.0 ml/min. DL-Thyronine.,5-Diiodo-L-thyronine.,',5-Triiodo-L-thyronine (T ) 4. L-Thyroxine (T 4 ) -50-

59 Food additives min Mobile Phase TCI Dual DS-AX0 (5μm) 4.6 mmi.d. X 50 mm A:CH C / 5 mmol/l CHCH 4 = 5 / 95 B:CH C / 50 mmol/l CHCH 4 = 70 / %B (0-5min), 00%B (5-0min) UV 54 nm.0 ml/min. L-Ascorbic Acid (Vitamin C). -Phenoxyethanol. Dehydroacetic Acid 4. Sorbic Acid 5. Benzoic Acid -5-

60 ,-Dimethylsulfamide S H min TCI Dual DS-CX5 (5μm) 4.6 mmi.d. X 50 mm Mobile Phase CH H / 0 mmol/l CHCH 4 (ph 6.88) = / 98 UV 0 nm.0 ml/min -5-