Mannatech ISKA- Certified Products

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1 Mannatech ISKA- Certified Products Through third-party testing and validation, certified products are ensured to be of the highest quality, free of undeclared contaminants and manufactured according to current Good Manufacturing Practices, or cgmps. The ISKA-certified seal started appearing on certain Mannatech product labels on July 10, An announcement was included in the BP8 (July 10, 2010) Insider product order insert, which was included in all North American product orders. Initially, the seal appears as a sticker; eventually, the seal will be integrated into printed product labels. The ISKA-certified seal appears on certified Mannatech products only in the U.S. and Canada at this time. See pages 8 11 for details about Mannatech s ISKA-certified products. Ambrotose Complex Powder & Capsules The original breakthrough Mannatech product based on Real Food Technology solutions, Ambrotose complex is an amazing and powerful daily supplement based on plant polysaccharides that provides your body with glyconutrients to improve the foundation of your wellness starting with your cells!* Research indicates the following benefits: >> Supports cell-to-cell communication through a blend of specific plant saccharides including glyconutrients.* >> Supports your immune system as well as proper organ function.* >> Helps support proper digestive system function.* >> Promotes gastrointestinal health.* >> May improve mood & decrease irritability.* >> May enhance recall & recognition memory.* While aloe vera has long been known to be extraordinarily beneficial to the human body, no one understood what ingredients made it so beneficial. That is, until the 1980s, when Mannatech scientists mined aloe vera for acemannan, a mannose-rich polysaccharide believed to be responsible for its immune-boosting benefits. They discovered and isolated a new class of nutrients glyconutrients from plant polysaccharides that help to complete the cellular alphabet of our body s communication system. The result Ambrotose complex.* Best T, Kemps E, Bryan J (2010) Saccharide effects on cognition and well-being in middle-aged adults: A randomized controlled trial. Developmental Neuropsychology 35(1): To read more about this study, go to MannatechScience.org/Products or the link: and download the PDF. NSF-Certified according to the NSF/ANSI 173 Dietary Supplement Standard the only American National Standard for dietary supplements. This certification ensures that this product contains only the ingredients indicated on the label and is free of impurities, and that Good Manufacturing Practices (GMPs) were used in the manufacturing facility. 8

2 Advanced Ambrotose Powder and Capsules Combining the power of Ambrotose complex (including mannose from aloe vera) and nutrient-rich wakame (a special type of brown seaweed), Advanced Ambrotose products are based on our Real Food Technology solutions to provide you with one of the most potent and healthy mixes of glyconutrients available to support immune function.* Mannatech s Advanced Ambrotose powder & capsules support: >> Immune system function.* >> Proper organ function.* >> Proper gland function.* >> Suitable for vegetarians.* Mannatech s Advanced Ambrotose products are based on a breakthrough formula that offers an advanced blend of saccharides. They combine saccharides from arabinogalactan and from aloe with fucoidan-rich Undaria pinnatifida, or wakame, a brown seaweed harvested from the clear waters off the coasts of Tasmania and Patagonia, for more fucoidans per serving than any other Mannatech product. What are fucoidans? Important polysaccharides that help support the immune system.* Ambrotose AO Capsules Stress from daily living produces free radicals, which can lead to a variety of health challenges. Mannatech s Ambrotose AO capsules combine a synergistic blend of plant extracts and antioxidant compounds with naturally sourced vitamins C and E for an extra-powerful punch of protection. Formulated using Real Food Technology solutions, these capsules: >> Protect your cells with water- and fatsoluble antioxidants.* >> Help the body guard against oxidative stress with antioxidant-rich nutrients.* >> Provide effective defense against free radicals.* Our Ambrotose AO capsules are a powerful combination of our antioxidant blend, MTech AO Blend formula; Ambrotose complex, which supports cellular health; and Phyt Aloe formula, which provides nutritional boosters. With this exceptional product in your daily regimen, free radicals don t have a chance. The Ambrotose AO capsules contain no animal products. Even the capsule itself is made from vegetable ingredients. Just two capsules a day are clinically proven, through human serum ORAC testing, to provide over 2 ½ times more antioxidant protection than five servings of fruits and vegetables! Comparison of serum ORAC values obtained in two separate clinical studies at least partially funded by Mannatech. Myers SP, Stevenson L, Cheras PA, et al. (2010) A forced titration study of the antioxidant and immunomodulatory effects of Ambrotose AO supplement. BMC Comp Alt Med 10, doi: / Boyd S, Gary K, Koepke CM, McAnalley S, Ford CR, Hore E et al. An open-label pilot study of the antioxidant effect in healthy people of Ambrotose AO. GlycoScience & Nutrition 2003; 4(6):1-6 To read these studies, go to MannatechScience.org/Publications or the link: and download the PDF. NSF-Certified according to the NSF/ANSI 173 Dietary Supplement Standard the only American National Standard for dietary supplements. This certification ensures that this product contains only the ingredients indicated on the label and is free of impurities, and that Good Manufacturing Practices (GMPs) were used in the manufacturing facility. 9

3 PhytoMatrix Caplets Born from Real Food Technology solutions, Mannatech s PhytoMatrix caplets contain foodsourced vitamins and phytonutrients from fruits and vegetables along with concentrated, plant-sourced minerals derived from hydroponically grown Indian mustard sprouts. These nutrient-dense caplets: >> Contain a natural, food-sourced vitamin/mineral complex for maximum absorption. >> Support heart health.* >> Offer antioxidant and immune system support.* >> Are gluten-free. >> Support the production of energy with B vitamins.* Why Is Hydroponics So Important? Some minerals are sourced from rocks. Some are taken from salts. But the minerals in PhytoMatrix caplets are from plants. They are harvested using a patented hydroponic process, in which Indian mustard sprouts are grown in a solution of highly concentrated minerals. This allows for standardized levels of minerals to be taken up into the sprouts and digested into the plant as a food form. This way, your body recognizes them so they may be more easily absorbed and digested.* And because the minerals are more concentrated, you re getting more for your money. PLUS Caplets Mannatech s PLUS caplets can help keep your endocrine system healthy. A healthy endocrine system produces a full array of hormones that can regulate your cells and organs. Using our Real Food Technology solutions, we created a blend of herbs and amino acids in PLUS caplets to help your body produce the hormones it needs to stay balanced and functioning optimally.* The PLUS caplets do not contain any hormones. Instead, they provide a unique blend of standardized nutrients, like those found in wild yam root, that help support your health in these areas: >> Furnishes raw materials for endocrine support.* >> Supplies amino acids to help support the endocrine system.* >> Supports breast, prostate, bone and colon health.* >> Supports health of immune, nervous and cardiovascular systems.* Your endocrine system is very busy and, ultimately, influences almost every cell, organ and function of your body. When we don t eat right, we can miss out on important nutrients like plant sterols and amino acids that help keep our systems functioning well. Our PLUS caplets fill in the missing nutrients and give your body the crucial support it needs.* NSF-Certified according to the NSF/ANSI 173 Dietary Supplement Standard the only American National Standard for dietary supplements. This certification ensures that this product contains only the ingredients indicated on the label and is free of impurities, and that Good Manufacturing Practices (GMPs) were used in the manufacturing facility. 10

4 BounceBack Capsules Mannatech s BounceBack capsules have a potent combination of natural ingredients clinically shown 1 to ease delayed onset muscle soreness (DOMS) that sore feeling in your muscles typically experienced 1 3 days after intense physical activity.* When taken daily over time, BounceBack capsules can : >> Aid the body s natural recovery process.* >> Help reduce muscle pain and stiffness due to overexertion or physical activity.* >> Support optimal joint and cartilage health.* >> Provide immune system support.* >> Deliver antioxidant support. Mannatech s BounceBack capsules are supported by a recent double-blind, placebo-controlled, crossover pilot study. 1 The study found that participants who took BounceBack capsules experienced significantly less muscle soreness than the placebo group. The study also found the participants had a significant increase in active energy expenditure, allowing them to stay active longer.* We all want to be active and mobile. But, as we get older, it gets more difficult. No matter what your age, overexertion can take a toll, and your body lets you know about it with muscle soreness and stiffness. Optimal Support Packets (OSPs) Take the hassle out of health with Optimal Support Packets, which contain an Ambrotose AO capsule and PhytoMatrix and PLUS caplets advanced daily nutrition in convenient packaging to support your active lifestyle. Formulated to help protect against nutritional deficiencies and oxidative stress, Optimal Support Packets are an answer for life on the go no matter what your nutritional goals.* Wellness in the palm of your hand: Contents of box: 56 individual packets >> Carry OSPs in your purse, briefcase of gym bag. >> Hand them out at the breakfast and dinner table. >> Take them on vacation without the hassle of packing multiple bottles. >> Keep a box in your office drawer. PLUS (2 caplets) Includes nutrients that help support the natural function of the endocrine, immune, nervous and cardiovascular systems as well as breast, prostate, bone and colon health.* Ambrotose AO (1 capsule) Powerful antioxidant support to help protect against cellular damage caused by the harmful effects of toxins, environmental stress, poor diet, daily physical stress and oxidative stress.* PhytoMatrix (2 caplets) Formulated to deliver natural vitamins, plant-sourced minerals and standardized phytonutrients. Allow 4 6 weeks for optimal benefits. 1 Udani, J., Singh, B., Singh, V. (2009). BounceBack capsules for reduction of DOMS after eccentric exercise: a randomized, double-blind, placebo-controlled, crossover pilot study. J Int Soc Sports Nutr, 6(14). Mannatech-sponsored study. To read this study, go to MannatechScience.org/Products or the link: and download the PDF. NSF-Certified according to the NSF/ANSI 173 Dietary Supplement Standard the only American National Standard for dietary supplements. This certification ensures that this product contains only the ingredients indicated on the label and is free of impurities, and that Good Manufacturing Practices (GMPs) were used in the manufacturing facility. 11

5 Additional Products In addition to the current ISKA-certified products, Mannatech has many other products that would be great to include in a Studio s Pro Shop. Simply Delicious Snack Bars What makes the perfect snack? It s one that s healthy, filling and flavorful and isn t loaded with empty calories. The surprisingly tasty and healthy Simply Delicious bars are filled with protein and fiber, so you ll feel full without filling up on calories. They are available in Chocolate Raspberry Truffle and Cherry Pie flavors. You won t feel guilty for indulging in this healthy snack. Simply Delicious Snack Bars: >> Produced with clean, renewable and sustainable solar energy. >> No artificial flavors, colors, sweeteners or preservatives. >> A Real Food Technology solution. >> USDA organic. >> GMO-free. >> Produced in a peanut-, wheat-, soy-, and dairy-free facility. It s Mannatech s first certified-organic product and the first to be made with solar energy, so they re not only good for you they re good for the environment too. The Simply Delicious snack bar is the smart way to snack. MannaBears Supplement Mannatech s MannaBears supplement is designed specifically for youngsters. These colorful, chewy bear-shaped supplements are sweetened with natural cane juice crystals and tapioca syrup. Your children will come back for them again and again. Parents know that getting kids to eat right is not always easy. Providing a beneficial alternative to sweets full of refined sugars and other junk foods can be especially difficult. The MannaBears chewy bear-shaped supplement provides Ambrotose complex and phytonutrients as a tasty way to help meet young people s nutritional needs during their growth years.* In addition to the specially formulated Ambrotose complex, MannaBears gummies include the phytonutritional goodness of 11 different dehydrated fruit and vegetable powders, including pomegranate juice, which is recognized as an excellent antioxidant, that protects cells from free radical damage and are gluten-free.* Best of all, they ll love the taste! 12

6 PhytoBurst Nutritional Chews Based on Real Food Technology solutions, tasty PhytoBurst Nutritional Chews help support your immune system, increase your energy and promote longevity and vitality. These convenient, great-tasting chews help your family members meet their daily nutritional needs.* Whether you re at home or on the go, PhytoBurst Nutritional Chews, packed with vitamins, minerals and phytonutrients, deliver a huge wellness punch. PhytoBurst Nutritional Chews: Enjoy two great flavors in each bag: lemon and mixed berry! >> Support your immune system.* >> Promote longevity and vitality.* >> Help keep your energy levels going.* >> Provide antioxidant support from broccoli, cranberry, grape and rutin.* >> Include naturally sourced ingredients. >> Contain delicious, all-natural flavoring. >> Are suitable for vegetarians. Getting good nutrition has never been so delicious. Mannatech s PhytoBurst soft chews support your diet with balanced nutrition. Inspired by Real Food Technology solutions, they re natural, safe and great for the whole family. Mannatech s PhytoBurst Nutritional Chews are the perfect pick-me-up between meals, before working out or to take on the go. They re individually wrapped, so they re convenient for your gym bag, desk drawer or briefcase. It s good nutrition that actually tastes good. Essential Source Omega-3 Using only the highest quality fish and a propriety two-step molecular distillation process, Mannatech s Essential Source Omega-3 provides an ultra-pure fish oil that delivers over 1,000 milligrams of health-benefitting EPA and DHA. A serving of our Essential Source Omega-3 provides 1110 milligrams of EPA and DHA and provides the following health benefits: >> Helps support cardiovascular and heart health.* >> Provides support for healthy triglyceride levels already within normal levels.* >> May support a more healthy balance of immune functions.* >> Helps support brain function and health.* Mannatech s Essential Source Omega-3 is: >> Ultra-pure, thanks to a proprietary, two-step molecular distillation process. >> A highly concentrated source of EPA and DHA. >> Naturally sourced. >> Formulated with a pleasant lemon flavor to prevent fishy aftertaste. Omega-3 essential fatty acids are essential to long-term health, but because your body can t produce them on its own, you must get them from diet or supplements. Inspired by Real Food Technology solutions, our Essential Source Omega-3 provides the essential fatty acids your body needs to maintain good health, especially brain and heart health. Health professionals agree it s a must, making omega-3 the leading brain and heart health supplement in the U.S.* 13

7 CardioBALANCE Heart Care Formula Mannatech s CardioBALANCE heart care formula provides nourishment for cardiovascular health.* The CardioBALANCE heart care formula is specifically designed to nourish your cardiovascular system through a unique herbal, vitamin and amino acid blend. It includes folate and L-arginine, thought to increase nitric oxide production, which is essential in maintaining blood vessel health, as well as CoQ10, which is often depleted by cholesterol-lowering drugs.* Among its many potential benefits, CardioBALANCE capsules help the body maintain homocysteine levels that are already within the normal range.* A daily serving of CardioBALANCE capsules supplies 100% or more of the daily value of important nutrients such as vitamin C and vitamin B6, which are necessary for normal fat metabolism, and folate, which is essential in maintaining blood vessel health. It also includes magnesium, which is necessary for normal protein synthesis.* The CardioBALANCE heart care formula is gluten-free. citrus-flavored drink mix is more than just a sports supplement drink. Its energy and endurance formula provides fuel and biochemicals clinically shown to enhance cardiorespiratory fitness and improve endurance. * Unlike popular, glucose-laden sports drinks that offer minimal benefits and trigger the release drink mix is formulated to help furnish biochemicals that can increase oxygen uptake capacity. The result nutritional support designed to increase workout intensity and duration.* drink mix has medium-chain triglycerides (MCTs) that are readily broken down into short-chain, free-fatty acids that are used as fuel for muscles.* citrus-flavored drink mix is gluten-free. Byars A, Keith S, Simpson W, et al. (2010) The influence of a pre-exercise sports drink (PRX) on factors related to maximal aerobic performance. J Int Soc Sports Nutr 7:16. To read this study, go to MannatechScience.org/Publications or the link: and download the PDF. 14

8 OsoLean Powder Mannatech s OsoLean powder is a specially formulated whey protein blend that includes an advanced peptide technology, which helps the body burn fat while maintaining lean muscle.* It helps improve the lean mass to fat ratio and helps you feel full.* Retention of lean muscle when burning fat is important in maintaining body strength and keeping your metabolism high. In a clinical study, the key ingredient in OsoLean powder promoted fat loss and minimized loss of muscle when combined with the OsoLean Plan and proper exercise.* Much more than just a typical whey protein, OsoLean powder is inspired by Real Food Technology solutions and includes an exclusive advanced peptide technology. Through a proprietary process, specific parts of whey protein, called peptides, are separated and concentrated to ensure the optimal level of fat-loss peptides. These peptides are blended with calcium-rich minerals from whey to make OsoLean powder.* Mannatech s OsoLean powder is great for mixing into beverages or food you already enjoy. Mannatech s OsoLean powder is gluten-free and certified Kosher. Usage & Availability of Products Usage Mannatech s products are labeled for adult use. The products are intended for use by persons aged 12 and above. Exceptions: >> MannaBears Supplements: All Ages >> PhytoBurst Nutritional Chews: Ages 4 and up >> Simply Delicious Snack Bars: All Ages Availability Our products are available only through Independent Mannatech Associates. When combined with the OsoLean Plan and proper exercise. Sinnott RQ, Maddela RL, Nelson ED, et al. (2009) The modifying effects of a calcium-rich whey protein supplement (OsoLean Powder) on weight loss and waist circumference in overweight subjects: a preliminary study. Open Nutraceuticals J 2: To read this study, go to MannatechScience.org/Publications or the link: and download the PDF. 15