CURRICULUM VITAE. Academic Appointments: 2000-present Instructor in Psychology, Department of Psychiatry, Harvard Medical School, Boston, MA.

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1 Prepared: 11/19/01 Name: Jane Ellen Anderson CURRICULUM VITAE Education: 1978 R.N. St. Elizabeth's Hospital School of Nursing 1987 B.S. Bridgewater State College 1991 M.S. Tufts University, Experimental Psychology 1996 Ph.D. Tufts University, Experimental Psychology Postdoctural Training: Fellowships: National Institute of Mental Health (NIMH) - Postdoctoral Clinical Research Training Fellow in Biological Psychiatry in the Clinical Neuroscience Division, Laboratory of Neuroscience, Harvard Medical School, Department of Psychiatry, Boston, MA NIMH Individual National Research Service Award (NRSA), Clinical Neuroscience Division, Laboratory of Neuroscience, Harvard Medical School, Department of Psychiatry, Boston, MA. Academic Appointments: 2000-present Instructor in Psychology, Department of Psychiatry, Harvard Medical School, Boston, MA. Professional Societies: American Psychological Association American Psychological Society Society for Neuroscience Society for Psychophysiological Research Cognitive Neuroscience Society Editorial Boards: 1995 ad hoc reviewer Cahiers de Psychologie Cognitive 1995 ad hoc reviewer Memory and Cognition 1995, 1997 ad hoc reviewer Psychophysiology ad hoc reviewer Biological Psychiatry Awards and Honors: 1986 Psi Chi National Honor Society 1987 Summa cum laude, Bridgewater State College NIMH National Research Service Award (NRSA) - Clinical Research Training Fellow Peter B. Livingston Award NIMH Individual National Research Service Award (NRSA)

2 Narrative report of Research: Schizophrenia is a disorder characterized by a diverse range of symptoms that manifest themselves in varying degrees in individual patients. Some symptoms, such as delusions, hallucinations, and disorganized speech and behavior, are known as "positive symptoms" because they are abnormal by their presence. Other symptoms, such as social withdrawal, blunted affect, and poverty of speech, are known as negative symptoms because they reflect the absence of normal behavior. One goal of this investigator s research is to gain a further understanding of brain structural abnormalities in schizophrenia patients. In particular, the investigator is interested in examining brain structural differences in patients who show either primarily positive symptoms or primarily negative symptoms. The technique of magnetic resonance imaging (MRI) is used to measure the volumes of temporal and prefrontal lobe structures. These structural measures in the two patient groups will be compared to a group of normal control subjects. Our hypothesis is that the symptomatogy will manifest itself in different patterns of structural brain abnormalities (with positive symptoms associated with reductions in temporal lobe volumes, and negative symptoms with reductions in prefrontal lobes). Schizophrenia is a disabling illness affecting one percent of the population. These findings will be important for gaining a further understanding of the link between clinical symptoms and structural abnormalities in schizophrenia. The investigator has also been involved in maintaining and developing a three dimensional atlas of the human brain for use in teaching neuroanatomy and in elastic matching. In this latter technique, the brain atlas is used as a template for automatic registration and warping of regions of interest, presently outlined using laborious manual techniques. Funding Information: NIMH National Research Service Award (NRSA) - Clinical Research Training Fellow Peter B. Livingston Award NIMH Individual National Research Service Award (NRSA) Clinical Symptoms in Schizophrenia: An MRI Study NIMH Individual National Research Service Award (NRSA) Clinical Symptoms in Schizophrenia: An MRI Study Report of Teaching: Local Contributions: Tufts University Summer 1993 Cognitive Psychology, Psychology Dept. Lecturer 6 undergraduates 20 hours/week for 6 weeks

3 Spring 1988 Fall 1987 Adolescent Psychology, Psychology Dept. Teaching Assistant 40 undergraduates 20 hours/week for 1 semester Introduction of Psychology, Psychology Dept. Teaching Assistant 200 undergraduates 20 hours/week for 1 semester Supervisory Role: Tanya Kisler Iris Fischer 1999 Seema Arora Sarah Corriveau Other: Consultant for Drs. Martha Shenton and Robert McCarley; administer and score the Thought Disorder Index. Bibliography Original Reports: 1. Holcomb PJ & Anderson JE. Cross-modal semantic priming: A time course analysis using event-related brain potentials. Language and Cognitive Processes 1993;8: Anderson JE & Holcomb PJ. Auditory and visual semantic priming using different stimulus onset asynchronies: An event-related brain potential study. Psychophysiology 1995;32: Chechile RA, Anderson JE, Krafczek SA, Coley SL. A Syntactic complexity effect with visual patterns: Evidence for the syntactic character for the memory representation of visual patterns. J Exp Psychol Learn Mem Cogn 1996;22: Kounios J, Litz B, Kaloupek D, Riggs D, Knight J, Weathers F, Anderson JE, Keane T. The electrophysiology of combat-related PTSD. Ann N y Acad Sci 1997;821: Holcomb PJ, Kounios J, Anderson JE, & West CW. Dual coding, context availability and concreteness effects in sentence comprehension: An electrophysiological investigation. J Exp Psychol Learn Mem Cogn 1999;20: Hirayasu Y, Shenton, ME, Salibury DF, Dickey CC, Fisher IA, Kisler T, Arakaki H,

4 Kwon JS, Anderson JE, Yurglelun-Todd D, Tohen M, McCarley RW. First episode schizophrenics differ from first episode affective psychotics and controls in left temporal lobe MRI volume reduction. Am J Psychiatry 1998;155: Anderson JE, Umans CM, Halle M, Rosenberg J, Golland P, McCarley RW, Shenton ME, Kikinis R. An interactive teaching tool of human anatomy using a java applet. RSNA Electronic Journal. Vol. 2, Online: 8. Potts GF, Guigino LD, Leventon ME, Grimson WEL, Kikinis R, Alexander E, Anderson JE, Ettinger GJ, Aglio LS, Shenton ME. Visual hemifield mapping using transcranial magnetic stimulation coregistered with cortical surfaces derived from magnetic resonance images. J Clin Neurophysiology 1998;15: Anderson JE, O Donnell BF, McCarley RW, Shenton ME. Progressive changes in schizophrenia: Do they exist and what do they mean? Restor Neurol Neurosci 1998; 55: Kwon JS, McCarley RW, Anderson JE, Hirayasu Y, Fischer IA, Kikinis R, Jolesz Fa, Shenton ME. Left Planum temporal volume reduction in schizophrenia. Arch Gen Psych 1999;56: Wible CG, Anderson J, Shenton ME, Kricun A, Hirayasu Y, Tanaka S, Levitt JJ, O Donnell BF, Kikinis R, Jolesz FA, McCarley RW. Prefrontal cortex, negative symptoms, and schizophrenia: An MRI study. Psychiatry Res: Neuroimaging (In Press). 12. Anderson JE, Wible CW, McCarley RW, Jakab M, Kasai K, Shenton ME. An MRI study of temporal lobe abnormalites and negative symptoms in chronic schizophrenia. Schizophr Res (In Press). Proceedings of Meetings: 1. Brown TJ, Salvador A, O'Hearn BE, & Anderson JE. Sentence orientation and semantic processing speed: Application to label design. Proceedings of the Human Factors Society 1989: Reviews, Chapters, and other Publications: 1. Holcomb PJ & Anderson JE. Similarities and differences in comprehension processes during reading and listening. In G Karmos, M Molnar, V Csepe, I Czigler, & JE Desmedt (Eds.) Perspectives of event-related potentials research (EEG Suppl. 44). Amsterdam: Elsevier;1995: Thesis: Anderson, JE. The effect of degree of learning on syntactic information analysis in visual pattern recognition. Tufts University, Medford, MA

5 Dissertation: Anderson JE. Anaphoric reference in text: An investigation using event-related brain potentials. Tufts University, Medford, MA Abstracts: 1. Anderson JE, & Holcomb PJ. An ERP study of auditory semantic priming using different stimulus onset asynchronies. Psychophysiology 1990;27:S Holcomb PJ, Kounios J, & Anderson JE. The N400 reflects differences in the processing of concrete and abstract words in semantically anomalous sentences. Psychophysiology 1992;29:S Anderson JE & Holcomb PJ.. Cross-modal repetition priming using different stimulus onset asynchronies: An event-related brain potential study. Psychophysiology 1992;29 S Holcomb PJ, Allen J, Ballerini S, Rosner D, & Anderson, J. Event-related brain potentials elicited by addition problems. Poster presented at 21st Annual Meeting of Society for Neuroscience, New Orleans Anderson JE & Holcomb PJ. A comparison of semantic and repetition priming using event-related brain potentials. Paper read at 65rd Annual Meeting of Eastern Psychological Association, April 14-17, Providence, RI. 6. Anderson JE & Holcomb PJ.. An electrophysiological study of cross-modal repetition priming effects. Poster presented at 23st Annual Meeting of Society for Neuroscience, Washington D.C Anderson JE & Holcomb PJ. A time course analysis of cross-modal repetition priming: An event-related potential study. Paper read at the American Meeting on Cognitive ERP Research, New York, July 29-31, Kotz SA, Anderson JE, and Holcomb PJ. Second language learning and semantic priming: An ERP Study. Paper read at the American Meeting on Cognitive ERP Research, Halifax, Nova Scotia, July 14-16, Anderson JE & Holcomb PJ. An event-related brain potential study of semantic and repetition priming. Paper read at the American Meeting on Cognitive ERP Research, Halifax, Nova Scotia, July 14-16, Anderson JE & Holcomb PJ. Coreference and event-related brain potentials. Poster presented at the Third Annual Meeting of the Cognitive Neuroscience Society, San Francisco, CA, March 31-April 2, Anderson JE & Holcomb PJ. The processing of noun anaphors: An event-related brain

6 potential study. The Sixth International Conference on Cognitive Neuroscience, Pacific Grove, CA, May 28-June 2, Hirayasu Y, Shenton ME, Salisbury DF, Fischer IA, Dickey CC, Kisler T, Anderson J, Kwon JS, Yurgelun-Todd D, Tohen M, McCarley RW. MRI abnormalities in firstepisode schizophrenia. Fifth Annual Research Day, Harvard Medical School. Sponsored by the Mysell Committee, Consolidated Department of Psychiatry, March 12, Dickey CC, Shenton ME, Fraone S, Niznikiewicz MA, Voglmaier MM, Seidman LJ, Hirayasu Y, Kwon JS, Anderson J, McCarley RW. Reduced left Heschl s gyrus volume in schizotypal personality disorder. Poster session, The 38th Annual Meeting of the American College of Neuropsychopharmacology, December 14, 1999, Acapulco, Mexico. 14. Dickey CC, Shenton ME, Fraone S, Niznikiewicz MA, Voglmaier MM, Seidman LJ, Hirayasu Y, Kwon JS, Fischer IA, Anderson J, Frumin M, McCarley RW. Reduced left Heschl s gyrus volume in schizotypal personality disorder. Biological Psychiatry 2000;47:13S. 15. Dickey CC, Shenton ME, Fraone S, Niznikiewicz M, Voglmaier MM, Seidman LJ, Hirayasu Y, Kwon JS, Fischer I, Sutton J, Anderson J, McCarley RW. Reduced left Heschl s gyrus volume in schizotypal personality disorder.eighth Annual Research Day, Harvard Medical School. Sponsored by the Mysell Committee, Consolidated Department of Psychiatry, April 5, 2000.

CURRICULUM VITAE Clinical Fellow in Psychiatry, Harvard Medical School Instructor in Psychiatry, Harvard Medical School

CURRICULUM VITAE Clinical Fellow in Psychiatry, Harvard Medical School Instructor in Psychiatry, Harvard Medical School CURRICULUM VITAE Education: 1973 A.B. Brandeis University 1990 M.S. University of California, Berkeley 1992 M.D. University of California, San Francisco Postdoctoral Training: 1992-93 Internship Psychiatry/Medicine,