Table 2. Participating Faculty Members

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1 Principal Investigator/ (Last, first, middle):, Donna, L. Table 2. Members Name/Degree(s) Rank Primary (& Secondary) Appointment(s) Role in Research Interest, Christopher MD, Timothy MD PhD Chen, Songhai MD PhD, Beverly PhD Frey Law, Laura MPT PhD, Donna PhD () Physical Therapy and Rehabilitation Science () Co-PD Resource Herr, Keela BSN PhD Nursing Adjunct Howard, Matthew MD Neurosurgery, Toshi PhD, Durga PhD () () PD Characterization of ASICs and their role in nociceptive, taste, and mechanical stimuli Mechanisms for peripheral sensitization in pathologic pain state How heterotrimeric G protein signaling regulates leukocyte migration and how aberrant G protein signaling contributes to tumor growth, metastasis and pain Development of novel molecular medicines for the treatment of genetic diseases Effects of pain and fatigue on motor function; mathematical muscle modeling Central and peripheral mechanisms of persistent pain Pain assessment and management in the older adult Neural basis of audition; Interventional approaches to pain management How diets affect the nervous system and modulate genetically inherited neurological defects Mechanisms of ion channel modulation that alter neuronal excitability in pain sensitization in cancers and inflammatory pathologies TABLE 2 Data Tables Page 137

2 Principal Investigator/ (Last, first, middle):, Donna, L. Name/Degree(s) Rank Primary (& Secondary) Appointment(s) Role in Research Interest Rakel, Barbara BSN PhD Nursing Adjunct Recober, Ana MD Neurology Junior Rosenthal, Gary MD Resource, Andy PhD Molecular Physiology/Biophysics (Neurology) Sluka, Kathleen PhD Physical Therapy and Rehabilitation Science Spofford, Christina MD PhD, Stefan PhD, Yuriy PhD, Michael MD MD/PhD Wu, Meng PhD Adjunct (Pathology) () Psychiatry Natural Products and Medicine Chemistry (Biochemistry) Junior Resource Non-pharmacologic interventions to reduce acute and persistent movement pain Mechanisms that underlie the progression from episodic to chronic migraine Comparative effectiveness research, patient centered outcomes research Molecular basis of migraine Neurobiology of musculoskeletal pain and analgesia Regional anesthesia; Mechanisms of acute pain Structure/function of protein phosphatase 2A (PP2A) and the role of PP2A in neuronal signal transduction and catecholamine synthesis, Molecular and cellular mechanisms that underlie pain sensitization induced by tissue or nerve injury and inflammation Diagnosis and therapy of lung disease; Biology of ASICs and their role in fear and neurological diseases. Mechanism for ASIC activation in vivo and its role in synaptic plasticity, Molecular probe/drug lead discovery via high-throughput screening and assay development TABLE 2 Data Tables Page 138

3 Principal Investigator/ (Last, first, middle):, Donna, L. Table 3. Institutional Training Grant Support Available to Members, Department(s), or (s) Neuroscience Training Medical Scientist Training Training in the Pharmacological Sciences 5 T32 GMS / T32 GM /1977-6/ T32 GM /2003-6/2017 Tranel, Daniel (Neurology) Lentz, Steve, Stefan () ( (13) (13) (7) Howard Sluka Chen Sluka Chen Data Tables Page 139

4 Principal Investigator/ (Last, first, middle):, Donna, L. Training in Genetics Cardiovascular Interdisciplinary Research Fellowship Training in Hypertension; Kidney Disease & Cell Biology Research Training in Pediatric Cardiology Research Training in the Major Psychoses and Clinical Neurobiology Bioinformatics Training in the Life Sciences and Biomedicine Research Training in Infectious Diseases in Hematology: Molecular & Cell Biology Blood Cells 5 T32 GM /1997-6/ T32 HL /1975-6/ T32 DK /1992-6/ T32 HL / T32 MH /1991-5/ T32 GM / T32 AI /1988-8/ T32 HL /1988-7/2014 Eberl, Daniel (Biology) Abboud, Francois Thomas, Christie Scholz, Thomas (Pediatrics) Andreasen, Nancy (Psychiatry) Casavant, Thomas (Electrical and Computer Engineering) Stapleton, Jack Lentz, Steve ( (4) (6) (3) Howard Data Tables Page 140

5 Principal Investigator/ (Last, first, middle):, Donna, L. Institutional Training in Oral Health Research 5 T32 DE Squier, Christopher (Dentistry) ( (3) Totals Data Tables Page 141

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