Liver imaging the revolution
|
|
- Caitlin Day
- 5 years ago
- Views:
Transcription
1 Liver imaging the revolution Valérie Vilgrain Hôpital Beaujon, Paris, France PHC
2 At the Beginning of the story
3 Radiology in the 1970s US Garrett Radiology 1976 abscess Taylor Radiology 1976 CT liver specimen liver mets Philips Radiology 1975 hepatic cyst Bryan Radiology 1977
4 Radiology in the 1980s MRI Radiology 1984 Liver mets
5 Chronic Chronic liver liver disease disease Tumor Tumor detection detection Tumor Tumor characterization characterization Tumor Tumor response response Morphological imaging
6 Chronic liver disease Cirrhosis Non cirrhotic: Portal cavernoma Budd-Chiari Biliary
7 Chronic liver disease Cirrhosis Non cirrhotic: Portal cavernoma Budd-Chiari Biliary
8 Chronic liver disease Cirrhosis Non cirrhotic: Portal cavernoma Budd-Chiari Biliary
9 Chronic liver disease Cirrhosis Non cirrhotic: Portal cavernoma Budd-Chiari Biliary
10 Tumor screening What are the clinical needs? Impact on patient management Impact on patient survival 17mm HCC Which patients High risk patients: chronic liver disease (HCC) Which imaging technique? Widely performed US Non invasive Wu, Gut 2015
11 Liver tumor staging What are the clinical needs? Impact on patient management Impact on patient survival Which patients 2010 Oncologic patients Surgical resection (colorectal liver metastases) Which imaging technique?
12 Liver tumor staging liver metastases Conventional Conventional DW-MR DW-MR HB HB contrast contrast agents agents T1, Restricted T1, T2 T2 Restricted Lesion Lesion enhancement enhancement diffusion diffusion Hypointensity Hypointensity on on HB HB phase phase
13 Liver tumor staging liver metastases Meta-analysis on liver mets 39 articles (1989 patients, 3854 liver metastases) MR Sensitivity (%) diffusion HB phase using Gadoxetic acid both 87.1% 90.6% 95.5% Higher Highersensitivity sensitivitywith withcombined combineddw DWand andhb HBphase phase Only Onlycolorectal colorectalliver livermets mets Liver Livermets mets<<11cm cm Neoadjuvant Neoadjuvantchemotherapy chemotherapy Histopathology Histopathologyalone aloneas asreference referencemethod method Translation in clinical practice? Vilgrain, Europ Radiol 2016
14 Liver tumor staging liver metastases VALUE study: 360 patients with suspected colorectal cancer liver metastases who had either gadoxetic acid enhanced MRI MRI with extracellular contrast medium or contrast-enhanced CT as a first-line imaging method in patients Gadoxetic A MR Regular MR CT Further imaging 0% 17% 39.3% Diagnostic confidence 98.3% 85.7% 65.2% Surgical changes 28% 32% 47% Zech, Br J Surgery 2014
15 Tumor characterization What are the clinical needs? Impact on patient management in all patients Incidental Incidental lesions lesions Mostly Mostly benign benign f/u? f/u? Rarely Rarely malignant malignant Hemangioma FNH Adenoma Oncologic Oncologic pts pts Mostly Mostly liver livermets mets some some benign benign 50% 50% <2cm <2cm Chronic Chronic liver liver diseases diseases HCC HCC Benign Benign nodules nodules
16 Tumor characterization HCC HCC Lesion enhancement FNH FNH CT CT MRI MRI CEUS CEUS hemangioma hemangioma
17 Tumor characterization Fat Hemorrhage Iron Highly cellular Hepatocellular
18 Tumor characterization Fat Hemorrhage Iron Highly cellular Hepatocellular
19 Tumor characterization Fat Hemorrhage Iron Highly cellular Hepatocellular
20 Tumor characterization Fat Hemorrhage Iron Highly cellular Hepatocellular
21 Tumor characterization Fat Hemorrhage Iron Highly cellular Hepatocellular MRI MRI
22 Tumor response RECIST criteria Complete response Partial response Progression
23 Can we push the morphological imaging forward? Probably marginally The revolution is elsewhere Quantitative Quantitativeimaging imaging Multiparametric Multiparametricimaging imaging Multimodal Multimodalapproach approach 3D 3Dassessment assessment
24
25 quantitative imaging
26 Quantitative imaging the big four Liver volume Fat quantification Murray Djokovic Iron quantification Nadal Federer Widely Widelyused used Highly Highlyreproducible reproducible Liver stiffness Validated Validated Clinical Clinicalimpact impact
27 Quantitative imaging liver volume Entire liver Prognostic factor in fulminant hepatic failure Future remnant liver critical predictor of perioperative outcomes after major liver resection Indicates portal vein embolization 1 mo Post-PVE pre-pve CC CC Tumor volume After Rt. hepatectomy CC CC CC CC Yamagishi, J Gastroenterol Hepatol 2005
28 Quantitative imaging fat NAFLD is the most frequent cause for referral for chronic liver disease and an increasing cause of HCC In patients undergoing liver resection, NAFLD increases the risk of postop complications and death In liver transplantation, presence of steatosis in the graft increases the risk of graft failure Berzigotti, J Hepatol 2014
29 Quantitative imaging fat with MRI MR spectroscopy direct measure of the chemical composition of tissue chemical-shift techniques (T1 GE) in-phase/out-of-phase (Dixon in 1984) IP OP Current Dixon-type sequences: Decomposition of water and fat with echo asymetry OP IP water fat
30 Fat-water Fat-waterseparation separationsequences sequences for forquantification quantification Steatosis Mild iron overload PDFF 29% T2*: 12 ms 25μmol/g No steatosis Mild iron overload PDFF 7% T2*: 5 ms 52μmol/g
31 Quantitative imaging liver stiffness Increased Increasedstiffness stiffnesscorrelates correlateswith withthe theamount amountof offibrosis fibrosis Treatment planning in chronic viral hepatitis depends on the degree of fibrosis In patients undergoing liver resection, marked fibrosis and cirrhosis increase the risk of postop complications and death Liver and spleen stiffness are correlated to the
32 Quantitative imaging liver stiffness Ultrasound Transient Elastography (TE) Integrated onto conventional US Acoustic Radiation Force Impulse (ARFI) ShearWave Elastography (SWE)
33 Fibroscan Ultrasound MRI availability dimension 1D 2D 3D performance Other data steatosis All US All MRI limitations Ascites, obesity few few
34 Quantitative imaging May Maybe beused usedcurrently currently poorly poorlyreproducible reproducible other Diffusion-weighted MRI b = 10 ADC, IVIM technique Insufficiently Insufficientlyvalidated validated D f D* Perfusion parameters Blood flow, blood volume Fingerprinting Simultaneous measure of T1 and T2 Liver function: acid Verloh, Europgadoxetic Radiol 2014 Saito, JMRI 2012 MELD 10 MELD >10
35 Conclusion Liver imaging is everyday morphological and multimodal The role of imaging biomarkers is increasing but few are validated Tomorrow imaging will be quantitative and multiscale: Radiomics Artificial Intelligence in Imaging is the next revolution and will change the practice
Functional liver imaging Bernard Van Beers
Functional liver imaging Bernard Van Beers Department of Radiology Beaujon University Hospital Paris Nord Laboratory of Imaging biomarkers UMR 1149 Inserm - University Paris Diderot France Functional imaging
More informationEvangelos Chartampilas Bioclinic Hospital Thessaloniki, Greece
Evangelos Chartampilas Bioclinic Hospital Thessaloniki, Greece Hepatospecificcontrast agents Gadobenate dimeglumine (Multihance) Gadoxeticacid (Primovist) 3-5% liver uptake 50% liver uptake Hepatobiliary
More informationNONINVASIVE IMAGING METHODS FOR ASSESSMENT OF LIVER DAMAGE IN NASH
NONINVASIVE IMAGING METHODS FOR ASSESSMENT OF LIVER DAMAGE IN NASH Bachir Taouli, MD Director of Body MRI and Cancer Imaging Program Department of Radiology / Translational and Molecular Imaging Institute
More informationInnovations in HCC Imaging: MDCT/MRI
Innovations in HCC Imaging: MDCT/MRI Anthony E. Cheng, M.D. Cardinal MRI Center Cardinal Santos Medical Center, Wilson Street, San Juan Innovations in HCC Imaging: Goals/Objectives MDCT/MRI Learn the diagnostic
More informationMR Elastography of Liver
MR Elastography of Liver Sudhakar K. Venkatesh, MD, FRCR Professor of Radiology Mayo Clinic College of Medicine Consultant, Abdominal Division Radiology, Mayo Clinic Rochester, MN, USA 19 th May 2018 2018
More informationAcknowledgements. Update of Focal Liver Lesions Goals. Focal Liver Lesions. Imaging Choices For Liver Lesions. Focal Liver Lesions
Acknowledgements Update of Focal Liver Lesions 2012 Giles Boland Massachusetts General Hospital Harvard Medical School No disclosures Dushyant Sahani Mukesh Harisinghani Goals Focal liver lesions Imaging
More informationLaboratory Tests and Diagnostic Procedures in Liver Disease: Adventures in Liverland
Laboratory Tests and Diagnostic Procedures in Liver Disease: Adventures in Liverland Sanjiv Chopra, MD, MACP Professor of Medicine Harvard Medical School Editor In Chief Hepatology Section Up To Date Serum
More informationNon-Invasive Testing for Liver Fibrosis
NORTHWEST AIDS EDUCATION AND TRAINING CENTER Non-Invasive Testing for Liver Fibrosis John Scott, MD, MSc Associate Professor, University of Washington Associate Clinic Director, Hep/Liver Clinic, Harborview
More informationPosthepatectomy Liver Failure. C. Jeske
Posthepatectomy Liver Failure C. Jeske Introduction Major source of morbidity and mortality after liver resection Devastating complication Little treatment Incidence: 4-19% Recently < 10% Mortality following
More informationMultidisciplinary Treatment Strategies for Primary and Metastatic Liver Cancers
Multidisciplinary Treatment Strategies for Primary and Metastatic Liver Cancers Ching-Wei D. Tzeng, M.D. Assistant Professor Surgical Oncology University of Kentucky Markey Cancer Center Affiliate Network
More informationImaging of liver and pancreas
Imaging of liver and pancreas.. Disease of the liver Focal liver disease Diffusion liver disease Focal liver disease Benign Cyst Abscess Hemangioma FNH Hepatic adenoma HCC Malignant Fibrolamellar carcinoma
More informationEvaluation of liver and spleen stiffness using a ultrasound guided method: Accuracy of ARFI(R) measurements in liver disease patients
Evaluation of liver and spleen stiffness using a ultrasound guided method: Accuracy of ARFI(R) measurements in liver disease patients Poster No.: C-3242 Congress: ECR 2010 Type: Topic: Authors: Keywords:
More informationEvaluation of Liver Mass Lesions. American College of Gastroenterology 2013 Regional Postgraduate Course
Evaluation of Liver Mass Lesions American College of Gastroenterology 2013 Regional Postgraduate Course Lewis R. Roberts, MB ChB, PhD Division of Gastroenterology and Hepatology Mayo Clinic College of
More informationJesse Civan, M.D. Medical Director, Jefferson Liver Tumor Center
Liver Tumors Jesse Civan, M.D. Medical Director, Jefferson Liver Tumor Center Differential Diagnosis Malignant Metastatic from non-hepatic primary Hepatocellular carcinoma Cholangiocarcinoma Biliary cystcarcinoma
More informationAlice Fung, MD Oregon Health and Science University
Alice Fung, MD Oregon Health and Science University Disclosure Comments The speaker Alice Fung, MD Has relevant financial relationships to disclose. Received honorarium from (Guerbet). This individual
More informationPROPOSTA DI UN NUOVO ALGORIMO PER LA DIAGNOSI ECOGRAFICA DELLE MALATTIE CRONICHE DEL FEGATO
PROPOSTA DI UN NUOVO ALGORIMO PER LA DIAGNOSI ECOGRAFICA DELLE MALATTIE CRONICHE DEL FEGATO A. Giorgio Direttore del servizio di Ecografia Interventistica Istituto Clinico S.Rita -IRCCS -Atripalda (Avellino)
More informationSimplifying liver assessment in internal medicine
Ultrasound Customer story Simplifying liver assessment in internal medicine Philips Affiniti ultrasound for elastography and contrast-enhanced ultrasound (CEUS) Where Sonography Institute, Uster, Switzerland
More informationLiver Ultrasound - Beyond the Basics. Pamela Parker Lead Sonographer
Liver Ultrasound - Beyond the Basics Pamela Parker Lead Sonographer Aims Review what we know about the liver Reasons for imaging Focal lesions Diffuse disease Can we do more? The Liver The Liver The Liver
More informationEvaluation of liver and spleen stiffness using a ultrasound guided method: Accuracy of ARFI(R) measurements in liver disease patients
Evaluation of liver and spleen stiffness using a ultrasound guided method: Accuracy of ARFI(R) measurements in liver disease patients Poster No.: C-3242 Congress: ECR 2010 Type: Topic: Authors: Keywords:
More informationLiver resection for HCC
8 th LIVER INTEREST GROUP Annual Meeting Cape Town 2017 Liver resection for HCC Jose Ramos University of the Witwatersrand Donald Gordon Medical Centre The liver is almost unique in that treatment of the
More informationTransient elastography the state of the art
Transient elastography the state of the art Laurent CASTERA, MD PhD Department of Hepatology, Hôpital Beaujon, Clichy Université Paris-7, France White Nights of Hepatology, St Petersburg, Russia, june
More informationLIVER IMAGING TIPS IN VARIOUS MODALITIES. M.Vlychou, MD, PhD Assoc. Professor of Radiology University of Thessaly
LIVER IMAGING TIPS IN VARIOUS MODALITIES M.Vlychou, MD, PhD Assoc. Professor of Radiology University of Thessaly Hepatocellular carcinoma is a common malignancy for which prevention, screening, diagnosis,
More informationWorkup of a Solid Liver Lesion
Workup of a Solid Liver Lesion Joseph B. Cofer MD FACS Chief Quality Officer Erlanger Health System Affiliate Professor of Surgery UTHSC-Chattanooga I have no financial or other relationships with any
More informationLiver Cancer And Tumours
Liver Cancer And Tumours What causes liver cancer? Many factors may play a role in the development of cancer. Because the liver filters blood from all parts of the body, cancer cells from elsewhere can
More informationLiver Tumors. Prof. Dr. Ahmed El - Samongy
Liver Tumors Prof. Dr. Ahmed El - Samongy Objective 1. Identify the most important features of common benign liver tumors 2. Know the risk factors, diagnosis, and management of hepatocellular carcinoma
More informationLiver surgery, acute GI tract bleeding
Semmelweis University, Faculty of Medicine, 1 st Department of Surgery Liver surgery, acute GI tract bleeding Oszkár HAHN M.D. LIVER CYST US, CT, MRI Parasite (ELISA, eosinophil, anaphylaxy) Echinococcus
More informationUltrasound elastography in abdominal imaging
Ultrasound elastography in abdominal imaging Olivier ucidarme Pitié Salpêtrière - UPMC Paris France Ultraschall Med. 013 Apr;34():169-84 Ultraschall Med. 013 Jun;34(3):38-53. US elastography Ultraschall
More informationULTRASOUND IN CHRONIC LIVER DISEASE
ULTRASOUND IN CHRONIC LIVER DISEASE Prof. Ioan Sporea, MD, PhD Head of Department of Gastroenterology and Hepatology University of Medicine and Pharmacy, Timişoara, Romania WFUMB Center of Education (COE),
More informationManagement of HepatoCellular Carcinoma
9th Symposium GIC St Louis - 2010 Management of HepatoCellular Carcinoma Overview Pierre A. Clavien, MD, PhD Department of Surgery University Hospital Zurich Zurich, Switzerland Hepatocellular carcinoma
More informationMRI OF FOCAL LESIONS IN
Introduction MRI OF FOCAL LESIONS IN THE NON-CIRRHOTIC LIVER Ivan Pedrosa M.D. Ph.D. Associate Professor of Radiology and Advanced Imaging Research Center University of Texas Southwestern. Dallas, TX Incidental
More informationLiver imaging takes a step forward with Ingenia
Publication for the Philips MRI Community ISSUE 49 2013 / 2 Liver imaging takes a step forward with Ingenia Lyon South Hospital strives to move from several studies first CT, then MR or PET to using just
More informationDiffuse Liver Disease:
Diffuse Liver Disease: MRI Evaluation Fat Iron Cirrhosis Donald G. Mitchell, M.D. Thomas Jefferson University Philadelphia, PA Fatty Liver Disease Common, increasing» Diabetes» Diet, high fructose corn
More informationWe don t need a liver biopsy. We have non-invasive tests
We don t need a liver biopsy We have non-invasive tests Laurent CASTERA, MD PhD Department of Hepatology, Hôpital Beaujon, Clichy Université Paris Diderot, France PHC 2018 www.aphc.info Liver biopsy: an
More informationByung Ihn Choi, M.D. Department of Radiology Seoul National University Hospital
Byung Ihn Choi, M.D. Department of Radiology Seoul National University Hospital CEUS & US Elastography : Contents CEUS Introduction Contrast agents & imaging Clinical application US Video WS Summary US
More informationContrast Enhanced Ultrasound of Parenchymal Masses in Children
Contrast Enhanced Ultrasound of Parenchymal Masses in Children Sue C Kaste, DO On behalf of Beth McCarville, MD St. Jude Children s Research Hospital Memphis, TN Overview Share St. Jude experience with
More informationHEPATO-BILIARY IMAGING
HEPATO-BILIARY IMAGING BY MAMDOUH MAHFOUZ MD PROF.OF RADIOLOGY CAIRO UNIVERSITY mamdouh.m5@gmail.com www.ssregypt.com CT ABDOMEN Indications Patient preparation Patient position Scanogram Fasting 4-6 hours
More informationBehandeling van colorectale levermetastasen. Rol van beeldvorming van de lever bij colorectaal carcinoom
Behandeling van colorectale levermetastasen Rol van beeldvorming van de lever bij colorectaal carcinoom B. Op de Beeck Universitair Ziekenhuis Antwerpen bart.op.de.beeck@uza.be 10.12.2016 AZ Turnhout campus
More informationThe Focal Hepatic Lesion: Radiologic Assessment
The Focal Hepatic Lesion: Radiologic Assessment Kevin Kuo, Harvard Medical School Year III Our Patient: PS 67 y/o female w/ long history of alcohol use Drinking since age 18, up to one bottle of wine/day
More informationInteresting Cases from Liver Tumor Board. Jeffrey C. Weinreb, M.D.,FACR Yale University School of Medicine
Interesting Cases from Liver Tumor Board Jeffrey C. Weinreb, M.D.,FACR Yale University School of Medicine jeffrey.weinreb@yale.edu Common Liver Diseases Hemangioma Cyst FNH Focal Fat/Sparing THID Non-Cirrhotic
More informationHEPATOCYTE SPECIFIC CONTRAST MEDIA: WHERE DO WE STAND?
HEPATOCYTE SPECIFIC CONTRAST MEDIA: WHERE DO WE STAND? Andrew T. Trout, MD @AndrewTroutMD Disclosures No relevant disclosures Outline Review of hepatocyte specific contrast media Review of hepatocellular
More informationUnderstanding your FibroScan Results
PATIENT & CAREGIVER EDUCATION Understanding your FibroScan Results This information will help you understand your FibroScan results. About FibroScan FibroScan is a specialized ultrasound machine for your
More informationCurrent Treatment of Colorectal Metastases. Dr. Thavanathan Surgical Grand Rounds February 1, 2005
Current Treatment of Colorectal Metastases Dr. Thavanathan Surgical Grand Rounds February 1, 2005 25% will have metastases at initial presentation 25-50% 50% will develop metastases later 40% of potentially
More informationRadiology of hepatobiliary diseases
GI cycle - Lecture 14 436 Teams Radiology of hepatobiliary diseases Objectives 1. To Interpret plan x-ray radiograph of abdomen with common pathologies. 2. To know the common pathologies presentation.
More informationUpdate on Non-Alcoholic Fatty Liver Disease. Timothy R. Morgan, MD Chief, Hepatology, VA Long Beach Professor of Medicine, UCI
Update on Non-Alcoholic Fatty Liver Disease Timothy R. Morgan, MD Chief, Hepatology, VA Long Beach Professor of Medicine, UCI February 3, 2018 Disclosure Clinical trials: Genfit Speaker s Bureau: none
More informationThe role of ARFI and APRI in diagnosis of liver fibrosis on patients with common chronic liver diseases
RESEARCH ARTICLE The role of ARFI and APRI in diagnosis of liver fibrosis on patients with common chronic liver diseases Objective: This study aimed to investigate the value of liver fibrosis assessment
More informationAASLD Immune tolerant phase HBV NAFLD diagnostic HCC
AASLD 2016 Immune tolerant phase HBV NAFLD diagnostic HCC Immune tolerant 3 Modified from Chan HLY and Wong VWS. Hepatitis B. In Zakim and Boyers s Hepatology 2012 2015 AMERICAN ASSOCIATION FOR THE S1T6UDY
More informationLOGIQ S8 XDclear 2.0 Liver Procedures
LOGIQ S8 XDclear 2.0 Liver Procedures See & quantify liver disease in a single exam Clinical Challenge Liver disease affects millions of people worldwide, and the number is growing. Clinicians need a cost-effective,
More informationPrognosis of NASH VII Workshop Intenracional de Actualizaçao em Hepatologia, Aug 29th 2014
Prognosis of NASH VII Workshop Intenracional de Actualizaçao em Hepatologia, Aug 29th 2014 Vlad Ratziu, Université Pierre et Marie Curie, Hôpital Pitié Salpêtrière, Paris, France NASH : a severe hepatic
More informationSurgical management of HCC. Evangelos Prassas Hepatobiliary and Pancreatic Surgery / Liver Transplantation Kings College Hospital / London
Surgical management of HCC Evangelos Prassas Hepatobiliary and Pancreatic Surgery / Liver Transplantation Kings College Hospital / London Global distribution of HCC and staging systems WEST 1. Italy (Milan,
More informationHepatocellular Carcinoma: Diagnosis and Management
Hepatocellular Carcinoma: Diagnosis and Management Nizar A. Mukhtar, MD Co-director, SMC Liver Tumor Board April 30, 2016 1 Objectives Review screening/surveillance guidelines Discuss diagnostic algorithm
More informationIn Search of New Biomarkers for Nonalcoholic Fatty Liver Disease
REVIEW In Search of New Biomarkers for Nonalcoholic Fatty Liver Disease Ting-Ting Chan, M.R.C.P., and Vincent Wai-Sun Wong, M.D. Nonalcoholic fatty liver disease (NAFLD) affects 15% to 40% of the general
More informationRICCARDO LENCIONI,CLOTILDE DELLA PINA, LAURA CROCETTI,DANIA CIONI. Chapter 1
RICCARDO LENCIONI,CLOTILDE DELLA PINA, LAURA CROCETTI,DANIA CIONI Chapter 1 Impact of European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines on the Use of Contrast
More informationA Review of Liver Function Tests. James Gray Gastroenterology Vancouver
A Review of Liver Function Tests James Gray Gastroenterology Vancouver Copyright 2017 by Sea Courses Inc. All rights reserved. No part of this document may be reproduced, copied, stored, or transmitted
More informationHepatic Imaging: What Every Practitioner Should Know
Hepatic Imaging: What Every Practitioner Should Know Shuchi K. Rodgers, MD Section Chief, Abdominal Imaging Director of Ultrasound Department of Radiology Einstein Medical Center rodgerss@einstein.edu
More informationWith the widespread use of hepatic imaging, liver masses
2B: Liver Assessment of the Liver Mass: What Do You Need to Know? With the widespread use of hepatic imaging, liver masses are detected either unexpectedly or in the course of screening for liver cancer
More informationFaculty Disclosure. Objectives. Cirrhosis Management for the Family Physician 18/11/2014
Cirrhosis Management for the Family Physician Mang Ma, MD, FRCP Professor University of Alberta Faculty: Mang Ma Faculty Disclosure Relationships with commercial interests: Advisory Board: Merck, Gilead
More informationMalignant Focal Liver Lesions
Malignant Focal Liver Lesions Other Than HCC Pablo R. Ros, MD, MPH, PhD Departments of Radiology and Pathology University Hospitals Cleveland Medical Center Case Western Reserve University Pablo.Ros@UHhospitals.org
More informationLearning Objectives. After attending this presentation, participants will be able to:
Learning Objectives After attending this presentation, participants will be able to: Describe HCV in 2015 Describe how to diagnose advanced liver disease and cirrhosis Identify the clinical presentation
More informationLiver surgery for colorectal liver metastases. Keith Roberts, Consultant Liver Transplant and Liver/Pancreas Surgeon University Hospitals Birmingham
Liver surgery for colorectal liver metastases Keith Roberts, Consultant Liver Transplant and Liver/Pancreas Surgeon University Hospitals Birmingham Introduction: what do we do? UHB Liver Unit: Liver resections
More informationFinancial Disclosure
Benign Liver Masses Adil Abdalla, MBBS Creighton University-CHI Health August 25, 2018 Financial Disclosure Nothing to disclose Financial Disclosure 1 Objectives To assess patients with benign liver tumors
More informationNon-Invasive Assessment of Liver Fibrosis. Patricia Slev, PhD University of Utah Department of Pathology
Non-Invasive Assessment of Liver Fibrosis Patricia Slev, PhD University of Utah Department of Pathology Disclosure Patricia Slev has no relevant financial relationships to disclose. 2 Chronic Liver Disease
More informationZoltan Harkanyi M.D., Ph.D. Department of Radiology, Heim Pal Children s Hospital, Budapest, Hungary
Zoltan Harkanyi M.D., Ph.D. Department of Radiology, Heim Pal Children s Hospital, Budapest, Hungary CEUS expereince 10 years Department of Radiology, Heim Pal Children s Hospital, Budapest US N o 1 study
More informationUS LI-RADS v2017 CORE
US LI-RADS v2017 CORE Screening or surveillance US in patient at high risk for HCC US category US-1 US-2 US-3 Negative Subthreshold Positive Category Concept Definition US-1 Negative US-2 Subthreshold
More informationNON INVASIVE EVALUATION OF DISEASE PROGRESSION IN CHRONIC LIVER DISEASES
Best of EASL -, Ethiopia 29 Sep to 01 Oct, 2016 Inaugural meeting of the Sub Saharan GI-Hepatology Working Group Incorporating Best of AGA and Best of EASL NON INVASIVE EVALUATION OF DISEASE PROGRESSION
More informationDIAGNOSIS OF NASH LIVER BIOPSY. PHC
DIAGNOSIS OF NASH LIVER BIOPSY PHC 2018 - www.aphc.info 1 THE NATURAL HISTORY OF NAFLD STEATOSIS (NAFL) STEATOHEPATITIS (NASH) FIBROSIS CIRRHOSIS HCC UNDER THE LENS : THE 3 HISTOLOGICAL COMPONENTS OF NAFLD
More informationClinical Trials & Endpoints in NASH Cirrhosis
Clinical Trials & Endpoints in NASH Cirrhosis April 25, 2018 Peter G. Traber, MD CEO & CMO, Galectin Therapeutics 2018 Galectin Therapeutics NASDAQ: GALT For more information, see galectintherapeutics.com
More informationElastography in the. technically difficult patient. EPIQ ultrasound system. Ultrasound
Ultrasound Elastography in the technically difficult patient EPIQ ultrasound system Chairman Department of Diagnostic Radiology Allegheny General Hospital Pittsburgh, PA, USA You can offer more information
More informationNewcastle HPB MDM updated radiology imaging protocol recommendations. Author Dr John Scott. Consultant Radiologist Freeman Hospital
Newcastle HPB MDM updated radiology imaging protocol recommendations Author Dr John Scott. Consultant Radiologist Freeman Hospital This document is intended as a guide to aid radiologists and clinicians
More informationNovel multiparametric magnetic resonance elastography (MRE) protocol accurately predicts NAS score for NASH diagnosis
Novel multiparametric magnetic resonance elastography (MRE) protocol accurately predicts NAS score for NASH diagnosis Alina M. Allen, Meng Yin, Sudhakar K. Venkatesh, Taofic Mounajjed, Todd A. Kellogg,
More informationIT 의료융합 1 차임상세미나 복부질환초음파 이재영
IT 의료융합 1 차임상세미나 2013-4-3 복부질환초음파 이재영 나는오늘누구를위하여 종을울리나? 전통적의료 의사 공학설계자 의사 최첨단진단장비들 USG, CT, MRI 환자 환자 현대의료 사용자중심의사고 US in the Abdomen Detection DDx Look Behavior Response by external stimuli Guiding Tool
More informationTREATMENT FOR HCC AND CHOLANGIOCARCINOMA. Shawn Pelletier, MD
TREATMENT FOR HCC AND CHOLANGIOCARCINOMA Shawn Pelletier, MD Treatment for HCC Treatment strategies Curative first line therapy Thermal ablation vs Resection vs Transplant Other first line therapies TACE
More informationEASL-EORTC Guidelines
Pamplona, junio de 2008 CLINICAL PRACTICE GUIDELINES: PARADIGMS IN MANAGEMENT OF HCC EASL-EORTC Guidelines Bruno Sangro Clínica Universidad de Navarra. CIBERehd. Pamplona, Spain Levels of Evidence according
More information6 th August 2018 Day 1 - Gallbladder & Bile duct Topic
Venue: Sterling Hospital Auditorium, Sterling Hospitals, Gurukul Road Ahmedabad, Gujarat 6 th August 2018 Day 1 - Gallbladder & Bile duct Registration(8:00am-8:15am) Inauguration(8:15am-8:30am) Welcome
More informationInvasive. Sampling error. Interobserver variability. Nondynamic evaluation of
How to assess liver fibrosis Serum markers or FibroScan vs. liver biopsy? Laurent CASTERA & Pierre BEDOSSA Hôpital Beaujon, AP-HP, Clichy Université Paris-VII France 4 th Paris Hepatitis Conference, Paris,
More informationTechniques to Improve Resectability of Colorectal Liver Metastases Ching-Wei D. Tzeng, M.D.
Techniques to Improve Resectability of Colorectal Liver Metastases Ching-Wei D. Tzeng, M.D. Department of Surgery Grand Rounds University of Kentucky January 15, 2014 Metastatic Colorectal Cancer (CRC)
More informationMANAGEMENT OF COLORECTAL METASTASES. Robert Warren, MD. The Postgraduate Course in General Surgery March 22, /22/2011
MANAGEMENT OF COLORECTAL METASTASES Robert Warren, MD The Postgraduate Course in General Surgery March 22, 2011 Local Systemic LIVER TUMORS:THERAPEUTIC OPTIONS Hepatoma Cholangio. Neuroendo. Colorectal
More informationResearch Elastography: Liver
Research Elastography: Liver Giovanna Ferraioli EFSUMB Ultrasound Learning Center Ultrasound Unit - Infectious Diseases Dept. Fondazione IRCCS Policlinico S. Matteo Medical School University of Pavia,
More informationSteatosi epatica ed HCV
Steatosi epatica ed HCV Malattie delle vie biliari ed Epatologia Rho, Auditorium Padri Oblati, 11 Novembre 2006 Piero L. Almasio Università di Palermo HISTOPATHOLOGY Steatosis and accelerated fibrogenesis:
More informationPediatric Hepatobiliary, Pancreatic & Splenic US
Pediatric Hepatobiliary, Pancreatic & Splenic US Susan J. Back, MD Department of Radiology, The Children s Hospital of Philadelphia No Disclosures Objectives Normal Abnormal: cases and US advances Objectives
More informationRadiation Therapy for Liver Malignancies
Outline Radiation Therapy for Liver Malignancies Albert J. Chang, M.D., Ph.D. Department of Radiation Oncology, UCSF March 23, 2014 Rationale for developing liver directed therapies Liver directed therapies
More informationUpdate EASL Clinical Practice Guidelines: Management of Hepatocellular Carcinoma
Update EASL Clinical Practice Guidelines: Management of Hepatocellular Carcinoma Peter R. Galle PHC 2018 - www.aphc.info Disclosure of Conflict of Interest Peter R. Galle I have the following financial
More informationInteresting case. Vikas Kundra, M.D., Ph.D. October Vikas Kundra, M.D., Ph.D.
Interesting case October 2012 Disclosure Information Vikas Kundra, M.D, Ph.D. I have no financial relationships to disclose. I WILL NOT include discussion of investigational or off-label use of a product
More informationTreatment of Colorectal Liver Metastases State of the Art
Treatment of Colorectal Liver Metastases State of the Art Eddie K. Abdalla, MD, FACS Professor and Chairman of Surgery Chief of Hepatobiliary Surgery Hilton Metropolitan Palace Hotel Beirut 16 November,
More informationPediatric Liver Tumors and Transplantation. Northwest Regional Pediatric Live Disease Symposium, Seattle WA, April 12, 2008
Pediatric Liver Tumors and Transplantation Northwest Regional Pediatric Live Disease Symposium, Seattle WA, April 12, 2008 Liver transplantation for primary liver tumours in children WHEN? - patient selection
More informationFactors associated with T2 Shine-Through Effect in Hepatic Hemangiomas on Diffusion-weighted MR Sequences
Factors associated with T Shine-Through Effect in Hepatic Hemangiomas on Diffusion-weighted MR Sequences Poster No.: C-09 Congress: ECR 014 Type: Scientific Exhibit Authors: R. Duran, M. Ronot, A. kerbaol,
More informationLiver Cancer (Hepatocellular Carcinoma or HCC) Overview
Liver Cancer (Hepatocellular Carcinoma or HCC) Overview Recent advances in liver cancer care seek to address the rising incidence of liver cancer, which has steadily increased over the past three decades.
More informationHepatobiliary Contrast Agents for Liver MRI
Hepatobiliary Contrast Agents for Liver MRI Scott B. Reeder, MD, PhD International Society for Magnetic Resonance in Medicine Sociedad Mexicana de Radiologia e Imagen (SMRI) Mexico City June 4, 2014 Department
More informationObjectives. HCC Incidence and Mortality. Disclosure Statement HCC. Imaging of Hepatocellular Carcinoma. Treatment of Hepatocellular Carcinoma
Imaging of Hepatocellular Carcinoma and the use of LI RADS Treatment of Hepatocellular Carcinoma Aaron D. Anderson, D.O. AOCR April 2015 Objectives Show how the use of LI RADS can simplify the diagnosis
More informationThe role of non-invasivemethods in evaluating liver fibrosis of patients with non-alcoholic steatohepatitis
The role of non-invasivemethods in evaluating liver fibrosis of patients with non-alcoholic steatohepatitis Objectives: Liver biopsy is the gold standard for diagnosing the extent of fibrosis in NAFLD/NASH;
More informationManagement of Liver Diseases: A Nonhepatologist s Viewpoint
Management of Liver Diseases: A Nonhepatologist s Viewpoint Arthur Y. Kim, MD Associate Professor of Medicine Harvard Medical School Director, Viral Hepatitis Clinic Massachusetts General Hospital Boston,
More informationEUROSON SCHOOL 2019 January 18-19, 2019, Athens-Greece Preliminary Programme
EUROSON SCHOOL 2019 January 18-19, 2019, Athens-Greece Preliminary Programme 08:00-09:00 Registration Friday, January 18 Theoretical Course / PHYSICS AND TECHNOLOGY 09:00-09:15 Basics in US Physics 09:15-09:30
More informationRadiology in Transplant
Curr Transpl Rep (2014) 1:238 245 DOI 10.1007/s40472-014-0034-5 LIVER TRANSPLANTATION (DC MULLIGAN, SECTION EDITOR) Radiology in Transplant Amy K. Kim & Michael L. Schilsky Published online: 19 September
More informationLiver MRI in 30 minutes
X Liver MRI in 30 minutes SCBT/MR Annual Meeting Salt Lake City September 18, 2016 Scott B. Reeder, MD, PhD Department of Radiology University of Wisconsin Madison, WI Disclosures University of Wisconsin-Madison
More informationAbdominal MRI Techniques in Pediatric Oncology
Abdominal MRI Techniques in Pediatric Oncology Jonathan R. Dillman, M.D. Assistant Professor Departments of Radiology & Urology Section of Pediatric Radiology C.S. Mott Children s Hospital Disclosures
More informationTransient elastography in chronic viral liver diseases
4 th AISF POST-MEETING COURSE Roma, 26 Febbraio 2011 Transient elastography in chronic viral liver diseases CRISTINA RIGAMONTI, M.D., Ph.D. Transient elastography (TE): a rapid, non-invasive technique
More informationNon-invasive diagnostic biomarkers
Non-invasive diagnostic biomarkers Liver Forum, November 12 th, 2015 Rohit Loomba, MD, MHSc Professor of Medicine (with tenure) Director, NAFLD Research Center, Division of Gastroenterology, Department
More informationESUR 2018, Sept. 13 th.-16 th., 2018 Barcelona, Spain
ESUR 2018, Sept. 13 th.-16 th., 2018 Barcelona, Spain OUR APPROACH Incidental adrenal nodule/mass Isaac R Francis, M.B;B.S University of Michigan, Ann Arbor, Michigan Disclosures None (in memory) M Korobkin,
More informationHow to integrate surgery in the treatment of patients with liver-only metastatic disease
How to integrate surgery in the treatment of patients with liver-only metastatic disease Luis Sabater Ortí MD, PhD Associate Professor University of Valencia European Board Surgical Qualification HBP (EBSQ-HPB)
More informationMRI for HCC surveillance and reporting: LI-RADS. Donald G. Mitchell, M.D. Thomas Jefferson University Philadelphia, PA
MRI for HCC surveillance and reporting: LI-RADS Donald G. Mitchell, M.D. Thomas Jefferson University Philadelphia, PA Cirrhotic Nodules Regenerative Nodule Atypical Nodule Hyperplastic Nodule Dysplastic
More information