D.O Midwestern Univ. Internal Medicine Cardiology Chief fellow Senior partner of a large cardiology group,

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4 D.O Midwestern Univ. Internal Medicine Cardiology Chief fellow Senior partner of a large cardiology group, Chairman of Dept. of Medicine Director of Cardiac Rehab Phoenix Top Doc 2011 Top Holistic MD 2012,

5 Millions of Procedures 5

6 Prescriptions Filled in the U.S., 2014 (Generic) The Real Causes of Heart Disease Poor nutrition Environmental pollutants Lack of sleep Subluxations Lack of sunshine Stress Physical inactivity Dehydration 6

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8 Dietary Cholesterol: No link to CAD - No link to CVA -Increased TC - Increased LDL -Increased HDL Meta-analysis on saturated fat and heart disease 350,000 people Saturated fat is not associated with an increased risk of heart disease Amer J. Clin Nutrition 2010 Children in Samoa eating coconuts 8

9 Paleo Versus SAD Paleo Versus SAD Paleo Proof Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross over pilot study. BACKGROUND: Our aim was to compare the effects of a Paleolithic ('Old Stone Age') diet and a diabetes diet as generally recommended on risk factors for cardiovascular disease in patients with type 2 diabetes not treated with insulin. METHODS: In a randomized cross over study, 13 patients with type 2 diabetes, 3 women and 10 men, were instructed to eat a Paleolithic diet based on lean meat, fish, fruits, vegetables, root vegetables, eggs and nuts; and a Diabetes diet designed in accordance with dietary guidelines during two consecutive 3 month periods. RESULTS: Study participants had on average a diabetes duration of 9 years, a mean HbA1c of 6,6% and were usually treated with metformin alone (3 subjects) or metformin in combination with a sulfonylurea or a thiazolidinedione. Mean average dose of metformin was 1031 mg per day. Compared to the diabetes diet, the Paleolithic diet resulted in lower mean values of HbA1c, triacylglycerol, diastolic blood pressure weight, BMI, waist circumference, and higher mean values of high density lipoprotein cholesterol. The Paleolithicdiet wasmainly lower incerealsanddairy and dairy products, andhigherin in fruits, vegetables, meat andeggs, as compared with the Diabetes diet. Further, the Paleolithic diet was lower in total energy, energy density, carbohydrate, dietary glycemic load, saturated fatty acids and calcium, and higher in unsaturated fatty acids, dietary cholesterol and several vitamins. Dietary GI was slightly lower in the Paleolithic diet than in the Diabetic diet. CONCLUSION: Over a 3 month study period, a Paleolithic diet improved blood sugar and several cardiovascular risk factors compared to a Diabetes diet. Cardiovasc Diabetol Jul 16 9

10 Beware of Your Morning Coffee 3 rd most sprayed crop per acre in the world after cotton and tobacco 10

11 Caffeine Genetics CYP 1A2 Leaky Gut Syndrome Vibrant- Wheat Zoomer 11

12 More Sunshine = Lower Risk of Cardiac Death The lower the latitude the lower the cholesterol 12

13 T CAPS AFCAPSex / Primary Prevention of Acute Coronary Events with Lovastatin Large primary prevention trial 5608 men aged 45 to 73; 997 women aged 55 to 73 in outpatient clinics in Texas Study was published in JAMA 1998 Mean TC 221, LDL 150, HDL 36, TG 158 Lovastatin or placebo Average follow up: 5.2 years AFCAPS/TexCAPS Primary Prevention of Acute Coronary Events with Lovastatin Total lmortality at 5 years 2.4% in the lovastatin group, 2.3% with placebo No statistical difference in women ( small # of endpoints) PROSPER Trial 5800 patients 50% women Aged History of, or risk factors for vascular disease Pravastatin or placebo 3.2 year follow-up The Lancet 2002; 360:

14 Stroke Death: 0.5% vs 0.8% Coronary Heart Disease Death: 4.2% vs 3.3% Cancer Death: 3.1% vs 4.0% 4.2% vs. 3.3% Total Mortality..No Difference 0.5% vs. 0.8% Cholesterol Metabolism 14

15 61% Higher Risk of Parkinson s Disease The 10 Health Commandments 1. Get responsible Paleo 2. Get sunshine 3. Get sleep 4. Get active 5. Get hydrated 6. Get adjusted 7. Get rid of stress 8. Get away from toxins 9. Get grounded 10. Get quality supplements 15

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18 Text PALEO to Paleo Shopping Guide 2. Boost your Nitric Oxide Levels Naturally 3. Top 20 Heart Healthy Supplements 17/10 18

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