A. Chutes and Ladders B. Jacks C. Candy Land D. Trouble

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1 Which president contracted smallpox a short time before delivering a famous speech? A. George Washington B. Abraham Lincoln C. Grover Cleveland D. Thomas Jefferson What famous author nearly died after intentionally exposing him/herself to a friend who had measles? A. Mark Twain B. Ralph Waldo Emerson C. Walt Whitman D. Margaret Fuller Roald Dahl, author of Charlie and the Chocolate Factory, lost his daughter to what vaccine-preventable disease? A. Diphtheria B. Measles C. Chickenpox D. Pneumococcal disease What famous kid s game was invented by Eleanor Abbott while she recovered from polio in a hospital ward? A. Chutes and Ladders B. Jacks C. Candy Land D. Trouble

2 The correct answer is A When Mark Twain was 12 years old, a measles epidemic swept through his town. Feeling like a prisoner in his own house, he decided to visit his friend who was sick with measles. Twain wrote about this experience in The Turning-Point of My Life. Abraham Lincoln became ill with smallpox a few days before delivering the Gettysburg Address. Current research suggests that the severity of Lincoln s illness was downplayed by his doctor to prevent the public from worrying that their president was dying. The correct answer is C Eleanor Abbott designed Candy Land in 1945 while she recovered from polio in a San Diego hospital ward. Candy Land was inducted into the National Toy Hall of Fame in Roald Dahl s daughter, Olivia, died at age 7 from encephalitis caused by measles. After Olivia s death, Roald became a vaccine advocate.

3 Although he died well before the vaccine was invented, Lewis Carroll, author of Alice in Wonderland, died from what vaccine-preventable disease? A. Smallpox B. Shingles C. Polio D. Influenza Ironically, what American died 10 years to the day before the first polio vaccine was licensed in the U.S.? A. Franklin Delano Roosevelt (FDR) B. James (Jimmy) Carter C. John F. Kennedy D. Abraham Lincoln The son of which U.S. president died in infancy due to influenza? A. Abraham Lincoln B. Franklin Delano Roosevelt C. George W. Bush D. Bill Clinton What U.S. president underwent smallpox variolation so he could conduct business in Boston without fearing the disease? A. John Adams B. Benjamin Franklin C. Thomas Jefferson D. Theodore Roosevelt

4 The correct answer is A Franklin Delano Roosevelt was diagnosed with polio at age 39, 12 years before becoming President of the United States. He died 10 years to the day before the first polio vaccine was licensed in the U.S. The irony was that Roosevelt was a tireless advocate of the polio vaccine program, starting a program known as the National Foundation for Infantile Paralysis, which later became the March of Dimes. The correct answer is D Lewis Carroll wrote many stories but is probably most famous for writing Alice in Wonderland and Through the Looking Glass. Lewis Carroll died from influenza in The correct answer is A Prior to becoming president, John Adams conducted a lot of business in Boston. During the 1760s, a smallpox epidemic broke out in Boston. Adams didn t want to risk infection or delay his work, so he was intentionally inoculated with smallpox, which was a common practice during that time. Known as variolation, the virus was taken from a pustule of one person and inoculated into another. Franklin Delano Roosevelt (FDR) and his wife Eleanor had their first child in Over the next 10 years, the Roosevelts had five more children, all of whom were boys. Unfortunately, one child became sick with influenza as an infant and died as a result.

5 Mary Mallon was a carrier of the bacterium Salmonella typhi and unknowingly made people sick. What was Mary s nickname when her carrier status was discovered? A. Pertussis Mary B. Mighty Mary the Cook C. Typhoid Mary D. Sick Mary Two NCAA basketball teams during the season played multiple games without any spectators due to an outbreak of what vaccine-preventable disease? A. Influenza B. Haemophilus influenzae type b C. Measles D. Pertussis What vaccine-preventable disease did Anne Frank suggest her dad was ill with while the family was hiding? Public funerals for victims of this vaccine-preventable disease were banned? A. Diphtheria B. Measles C. Rubella D. Tetanus A. Tuberculosis B. Diphtheria C. Cholera D. Polio

6 The correct answer is C A measles outbreak during the basketball season caused Siena College (New York) and the University of Hartford (Connecticut) basketball teams to play five games each without spectators. Interestingly, both teams played better in the absence of fans, scoring more points and attaining higher free-throw percentages. The correct answer is C Nicknamed Typhoid Mary, Mary Mallon was the first carrier of Salmonella typhi in the United States who showed no symptoms of the illness. As a cook, Mary infected 51 people, three of whom died. She was put in isolation twice to prevent her from further spreading the disease. The correct answer is D Because the cause and contagiousness of polio was unknown and the panic was fierce, things like public funerals for victims were banned. In addition, swimming pools, churches and cinemas were closed during the summer months or polio season. During World War II while Jewish families were in hiding from the Germans, they could not get medical care, so it is not confirmed that Otto Frank had measles. However, Anne described her dad as being ill with a high fever and rash illness.

7 Americans donated enough dimes toward polio research during the March of Dimes campaign to stretch from where to where? A. New York to Moscow B. Los Angeles to New York C. New York to Chicago D. Boston to Florida What disease was the focus of research during WWII because of the number of soldiers it killed during WWI? A. Polio B. Influenza C. Measles D. Chickenpox Which vaccinologist is buried in Arlington National Cemetery? A. Jonas Salk B. Basil O Connor C. Simon Flexner D. Albert Sabin What famous philanthropist said vaccines are a miracle, and that with just a few doses, they can prevent deadly diseases for a lifetime? A. Oprah B. Bill Gates C. Warren Buffett D. George Clooney

8 During WWI, the U.S. Military lost more soldiers to Spanish Influenza than those killed by the enemy. Therefore, research into influenza vaccines and treatment was a major military focus between the end of WWI and WWII. The correct answer is A By 1952, Americans had answered the call of the National Foundation for Infantile Paralysis (NFIP, later known as the March of Dimes), and donated enough dimes to stretch from New York to Moscow. The donations were used to establish rehabilitation centers, support families, transport iron lungs into areas of outbreak and to fund vaccine research. Bill Gates, founder of Microsoft, is a known vaccine advocate and founder of End Polio Now, an initiative working toward global polio eradication. The correct answer is D Albert Sabin had retained the rank of lieutenant colonel in the U.S. Army. His tombstone carried the inscription: SABIN. Developer of the vaccine that made possible the global eradication of poliomyelitis.

9 What famous 1970s/1980s singer caught polio during the 1951 pandemic? A. Freddie Mercury B. Jon Bon Jovi C. Neil Young D. John Lennon Jane Austen, author of Pride and Prejudice, died from what vaccine-preventable disease? A. Smallpox B. Rubella C. Tuberculosis D. Diphtheria Sacajawea is said to have died from what vaccine-preventable disease? A. Rubella B. Chickenpox C. Shingles D. Diphtheria The iron lung design used in America was nicknamed after which animal? A. Hippopotamus B. Alligator C. Crocodile D. Tiger

10 The correct answer is C Besides Pride and Prejudice, Jane Austen wrote many great literary works including Northanger Abbey, Persuasion, and Sense and Sensibility. During her lifetime, Jane s work did not offer much in the way of fame. However, upon the publication of her nephew s book, A Memoir of Jane Austen, Jane Austen s work became much more well-known and she was recognized as a great English writer. The correct answer is C In 1951, the last major polio outbreak occurred in Ontario, Canada. Neil Young, who was only a child at the time, became sick with the disease. After surviving the illness, Neil Young grew up to become a successful musician and was inducted into the Rock and Roll Hall of Fame twice. The iron lung got this nickname because of its hinged top half, which could be lifted up to engulf the patient. It was an improvement on the original design since it was lighter, cheaper and made nurses tasks with patients much easier. The correct answer is D Sacajawea was the Native American Indian interpreter and guide for the Lewis and Clark expeditions. She is said to have died from diphtheria.