FERTISAFE PLUS US PL AFE TIS FER
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1 FERTISAFE PLUS FERTISAFE PLUS
2 FERTISAFE PLUS Broad Spectrum Antimicrobial Disinfectant Fertisafe Plus is a long lasting, CE marked, ready to use broad spectrum antimicrobial disinfectant. Quaternary Ammonium free and odourless, it is proven to kill bacteria, viruses and fungi, yet is embryo and sperm safe. 39
3 FERTISAFE PLUS Fertisafe Plus Spray Fertisafe Plus Refill 3 YEAR SHELF LIFE 1 Offering up to 24 hour residual protection Long lasting disinfectant PROVEN SAFETY Each batch is MEA and HSSA tested, is embryo and sperm-safe and Quaternary Ammonium (DDAC) Free 2 POWERFUL PROTECTION Bactericidal and virucidal in seconds and fungicidal in minutes 1,2 Please see references on page
4 FERTISAFE PLUS REVOLUTIONARY The revolutionary patented antimicrobial molecule Silver Dihydrogen Citrate (SDC) starts killing bacteria and viruses in seconds. A routine clean will only take two minutes and a deeper clean just ten minutes. It disinfects quickly and efficiently without exposing samples to harmful Volatile Organic Compounds (VOCs). When used as directed, Fertisafe Plus provides residual protection from Pseudomonas aeruginosa, Staphylococcus aureus and Salmonella enterica for up to 24 hours after an application of two minutes. Fertisafe Plus comes in a practical, ready to use spray bottle as well as a litre refill bottle. 1 From date of manufacture. 2 Refer to Sterility and Biocompatibility Testing on the website: 3 Quaternary Ammonium Compounds may cause birth defects - Susiargo, M & Hunt, P. Bisphenol A exposure disrupts egg development in the mouse. Fertility Sterility, (2 suppl):pg97. Maher, Brendan Lab disinfectant harms mouse fertility, Nature [online], Available at: news/2008/080618/full/453964a.html SDC POWER AGAINST ORGANISMS SDC works in two ways to kill microorganisms. Firstly, the silver ion deactivates structural and metabolic membrane proteins leading to microbial death; secondly, the microbes view SDC as a food source, allowing the silver ion to enter the microbe. Once inside the organism, the silver ion denatures the DNA, halting the microbe s ability to replicate and leading to its death. This dual action makes SDC highly and quickly effective against a broad spectrum of microbes. UNIQUE DISINFECTANT Fertisafe Plus is a class IIa medical device in Europe and is CE marked as such; the only CE marked disinfectant for ART. NON-TOXIC & ODOURLESS Fertisafe Plus is non-toxic, colourless and does not produce toxic fumes. Odourless and non-caustic as well, it is kind to users and will effectively eliminate the bacteria, viruses and fungi found in any IVF laboratory. It contains no Quaternary Ammonium Compounds which may cause birth defects. 3 Fertisafe Plus is proven to be both a safe and powerful disinfectant. Each batch undergoes MEA testing (pass criteria 2-cells at day 2 80%, expanded blastocysts at day 6 80%) and HSSA testing (pass criteria 70% motility at 24 hours) routinely ensuring the safety of both embryos and sperm. Certificates of Analysis are available for each batch. 41 CE MARKED AS A MEDICAL DEVICE FINISHED PRODUCT MEA TESTED FINISHED PRODUCT LAL TESTED
5 EFFECTIVE AGAINST A BROAD SPECTRUM OF MICROBES Fertisafe Plus successfully rendered inactive all organisms listed in the following table. BACTERIA CONTACT TIME VIRUSES CONTACT TIME Pseudomonas aeruginosa HIV Type 1 Salmonella enterica (formerly Salmonella choleraesuis) Staphylococcus aureus Listeria monocytogenes Vancomycin-resistant Enterococcus faecium (VRE) Methicillin-resistant Staphylococcus aureus (MRSA) Rotavirus Human Coronavirus Influenza A (H1N1) Swine Influenza A (H1N1) Respiratory Syncytial Virus Adenovirus Type 2 Hepatitis B Virus (HBV) Community associated Methicillin-resistant Staphylococcus aureus (CA-MRSA) Hepatitis C Virus (HCV) Herpes Simplex Type 1 Escherichia coli O157:H7 Murine Norovirus Acinetobacter baumannii Norovirus Campylobacter jejuni Influenza A Carbapenem-resistant Esherichia coli Avian Influenza A Carbapenem-resistant Klebsiella pneumoniae Carbapenem-resistant Klebsiella pneumonia, NDM-1 Rhinovirus Poliovirus Type 2 FUNGUS CONTACT TIME Enterococcus hirae 10 Minutes Candida albicans 10 Minutes 42
6 Research Instruments Ltd, Bickland Industrial Park, Falmouth, Cornwall, TR11 4TA, UK tel: +44 (0) fax: +44 (0) visit: MKTG-BR /06/2015. All information correct at time of print. Specifications are subject to change without notice or obligation on the part of the manufacturer.
I can confidently use the EZ-Range for all embryological handling procedures and rest assured that the eggs/ embryos are secure during movement.
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