OIE Reference Laboratory Reports Activities
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1 OIE Reference Laboratory Reports Activities Activities in 2017 This report has been submitted : :49:33 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Classical swine fever Address of laboratory: Animal Health Research Institute (AHRI) Division of Hog Cholera 376 Chung-Cheng Rd Tamsui District New Taipei City CHINESE TAIPEI Tel.: Fax: address: cychang@mail.nvri.gov.tw Website: Name (including Title) of Head of Laboratory (Responsible Official): Chia-Yi Chang: Associated Researcher Name (including Title and Position) of OIE Reference Expert: Chia-Yi Chang: Associated Researcher Which of the following defines your laboratory? Check all that apply: Governmental OIE Reference Laboratory Reports Activities,
2 ToR 1: To use, promote and disseminate diagnostic methods validated according to OIE Standards 1. Did your laboratory perform diagnostic tests for the specified disease/topic for purposes such as disease diagnosis, screening of animals for export, surveillance, etc.? (t for quality control, proficiency testing or staff training) Diagnostic Test Indicated in OIE Manual (/) Total number of test performed last year Indirect diagnostic tests Nationally Internationally CSF Virus neutralization test Direct diagnostic tests Nationally Internationally CSF Virus isolation CSF Real-time RT-PCR 39 0 Panpesti Real-time RT-PCR ToR 2: To develop reference material in accordance with OIE requirements, and implement and promote the application of OIE Standards. To store and distribute to national laboratories biological reference products and any other reagents used in the diagnosis and control of the designated pathogens or disease. 2. Did your laboratory produce or supply imported standard reference reagents officially recognised by the OIE? 3. Did your laboratory supply standard reference reagents (non OIE-approved) and/or other diagnostic reagents to OIE Member Countries? 2 OIE Reference Laboratory Reports Activities, 2017
3 Type of reagent available Related diagnostic test Produced/ provide Amount supplied nationally (ml, mg) Amount supplied internationally (ml, mg). of recipient OIE Member Countries Region of recipients RNA of virus isolates Reverse-transcription polymerasechain reaction Produced 0 200ul x 6 1 Africa Americ as Asia and Pacific Europe Middle East Reference sera for CSFV Antibody ELISA Produced 0 1ml x 6 1 Africa Americ as Asia and Pacific Europe Middle East 4. Did your laboratory produce vaccines? 5. Did your laboratory supply vaccines to OIE Member Countries? ToR 3: To develop, standardise and validate, according to OIE Standards, new procedures for diagnosis and control of the designated pathogens or diseases 6. Did your laboratory develop new diagnostic methods validated according to OIE Standards for the designated pathogen or disease? 7. Did your laboratory develop new vaccines according to OIE Standards for the designated pathogen or disease? ToR 4: To provide diagnostic testing facilities, and, where appropriate, scientific OIE Reference Laboratory Reports Activities,
4 and technical advice on disease control measures to OIE Member Countries 8. Did your laboratory carry out diagnostic testing for other OIE Member Countries? 9. Did your laboratory provide expert advice in technical consultancies on the request of an OIE Member Country? ToR 5: To carry out and/or coordinate scientific and technical studies in collaboration with other laboratories, centres or organisations 10. Did your laboratory participate in international scientific studies in collaboration with OIE Member Countries other than the own? Title of the study Duration Purpose of the study Partners (Institutions) OIE Member Countries involved other than your country Development of technologies for preventing invasion and spread of transboundary animal infectious diseases Validation of new diagnostic methods of porcine reproductive and respiratory syndrome and classic swine fever National Institute of Animal Health JAPAN ToR 6: To collect, process, analyse, publish and disseminate epizootiological data relevant to the designated pathogens or diseases 11. Did your Laboratory collect epizootiological data relevant to international disease control? 12. Did your laboratory disseminate epizootiological data that had been processed and analysed? 13. What method of dissemination of information is most often used by your laboratory? (Indicate in the appropriate box the number by category) a) Articles published in peer-reviewed journals: 3 4 OIE Reference Laboratory Reports Activities, 2017
5 Huang YL, Deng MC, Tsai KJ, Liu HM, Huang CC, Wang FI, Chang CY. Competitive replication kinetics and pathogenicity in pigs co-infected with historical and newly invading classical swine fever viruses. Virus Res Jan 15; 228: Meyer D, Fritsche S, Luo Y, Engemann C, Blome S, Beyerbach M, Chang CY, Qiu HJ, Becher P, Postel A. The double-antigen ELISA concept for early detection of Erns-specific classical swine fever virus antibodies and application as an accompanying test for differentiation of infected from marker vaccinated animals. Transbound. Emerg. Dis Dec; 64(6): Postel A, Meyer D, Cagatay GN, Feliziani F, De Mia GM, Fischer N, Grundhoff A, Milićević V, Deng MC, Chang CY, Qiu HJ, Sun Y, Wendt M, Becher P. The novel atypical porcine pestivirus (APPV) was detected in pig populations of different regions in Europe and Asia with high genome and antibody prevalence and therefore must be considered to be a pathogen of global relevance. Emerg. Infect, Dis (Accepted) b) International conferences: 0 c) National conferences: 3 Chang CY. Diagnosis and control of classical swine fever. Classical swine fever diagnosis and prevention workshop. June 22, New Taipei City, Taiwan. Chang CY. Pathogenesis, global situation and control of classical swine fever. Official veterinarians education and training. Aug 21, Taipei City, Taiwan. Chang CY. Introduction of the OIE reference laboratory for classical swine fever. Meeting of the eradication program of classical swine fever and foot and mouth disease. Dec 19, Kaoshiung, Taiwan. d) Other: (Provide website address or link to appropriate information) 0 ToR 7: To provide scientific and technical training for personnel from OIE Member Countries To recommend the prescribed and alternative tests or vaccines as OIE Standards 14. Did your laboratory provide scientific and technical training to laboratory personnel from other OIE Member Countries? ToR 8: To maintain a system of quality assurance, biosafety and biosecurity relevant for the pathogen and the disease concerned 15. Does your laboratory have a Quality Management System certified according to an International Standard? OIE Reference Laboratory Reports Activities,
6 Quality management system adopted ISO/IEC 17025:2005 Certificate scan (PDF, JPG, PNG format) TAF_Certificate scan pdf 16. Is your laboratory accredited by an international accreditation body? Test for which your laboratory is accredited CSF Virus neutralization test CSF Virus isolation CSF Real-time RT-PCR Accreditation body ILAC-TAF ILAC-TAF ILAC-TAF 17. Does your laboratory maintain a biorisk management system for the pathogen and the disease concerned? (See Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, Chapter 1.1.4) ToR 9: To organise and participate in scientific meetings on behalf of the OIE 18. Did your laboratory organise scientific meetings on behalf of the OIE? 19. Did your laboratory participate in scientific meetings on behalf of the OIE? ToR 10: To establish and maintain a network with other OIE Reference Laboratories designated for the same pathogen or disease and organise regular inter-laboratory proficiency testing to ensure comparability of results 20. Did your laboratory exchange information with other OIE Reference Laboratories designated for the same pathogen or disease? 21. Was your laboratory involved in maintaining a network with OIE Reference Laboratories designated for the same pathogen or disease by organising or participating in proficiency tests? 6 OIE Reference Laboratory Reports Activities, 2017
7 Purpose of the proficiency tests: 1 Role of your Reference Laboratory (organiser/ participant). participants Participating OIE Ref. Labs/ organising OIE Ref. Lab. Classical Swine Fever (CSF) Inter-laboratory Comparison Test 2017 participant Organiser: University of Veterinary Medicine Hannover, Institute of Virology EU and OIE Reference Laboratory for CSF 1 validation of a diagnostic protocol: specify the test; quality control of vaccines: specify the vaccine type, etc. 22. Did your laboratory collaborate with other OIE Reference Laboratories for the same disease on scientific research projects for the diagnosis or control of the pathogen of interest? Title of the project or contract Scope Name(s) of relevant OIE Reference Laboratories Evaluation of the double-antigen ELISA concept for early detection of Erns-specific classical swine fever virus antibodies Application as a CSFV antibody screening ELISA including usage as an accompanying discriminatory test for CSFV marker vaccines University of Veterinary Medicine Hannover, Institute of Virology EU and OIE Reference Laboratory for CSF Diagnostic and epidemiological research of various pig diseases Molecular and antibody screening with the sera for discovery /characterization of novel pig viruses University of Veterinary Medicine Hannover, Institute of Virology, EU and OIE Reference Laboratory for CSF Characterization of monoclonal antibodies against classical swine fever virus Exchange of information on: 1) Monoclonal antibodies against CSFV; 2) Epitope mapping of the structural protein E2 of CSFV University of Veterinary Medicine Hannover, Institute of Virology, EU and OIE Reference Laboratory for CSF ToR 11: To organise inter-laboratory proficiency testing with laboratories other than OIE Reference Laboratories for the same pathogens and diseases to ensure equivalence of results 23. Did your laboratory organise or participate in inter-laboratory proficiency tests with laboratories other than OIE Reference Laboratories for the same disease? te: See Interlaboratory test comparisons in: Laboratory Proficiency Testing at: see point 1.3 OIE Reference Laboratory Reports Activities,
8 ToR 12: To place expert consultants at the disposal of the OIE 24. Did your laboratory place expert consultants at the disposal of the OIE? Kind of consultancy Location Subject (facultative) Review of OIE Standards by Update the vaccine section of the Terrestrial Manual chapter on classical swine fever 25. Additional comments regarding your report: 8 OIE Reference Laboratory Reports Activities, 2017
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-31 14:46:00 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Newcastle
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OIE Reference Laboratory Reports Activities Activities in 2015 This report has been submitted : 2016-03-08 23:26:29 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Transmissible
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2013 This report has been submitted : 2014-01-31 21:38:48 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: n
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-03-02 17:47:42 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Highly
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OIE Reference Laboratory Reports Activities Activities in 2013 This report has been submitted : 2014-02-18 20:17:32 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Crimean-Congo
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OIE Reference Laboratory Reports Activities Activities in 2013 This report has been submitted : 2014-01-31 12:34:26 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Newcastle
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2017 This report has been submitted : 2017-12-21 15:32:58 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Classical
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OIE Reference Laboratory Reports Activities Activities in 2014 This report has been submitted : 2015-01-16 03:37:00 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-12 10:32:31 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-05 21:59:05 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Avian
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OIE Reference Laboratory Reports Activities Activities in 2015 This report has been submitted : 2016-01-17 13:49:58 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Highly
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OIE Reference Laboratory Reports Activities Activities in 2015 This report has been submitted : 2016-01-18 11:23:08 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Equine
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OIE Reference Laboratory Reports Activities Activities in 2016 This report h been submitted : 2017-01-06 10:23:58 Name of disee (or topic) for which you are a designated OIE Reference Laboratory: Equine
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OIE Reference Laboratory Reports Activities Activities in 206 This report h been submitted : 207-0-2 0:27:9 Name of disee (or topic) for which you are a designated OIE Reference Laboratory: Swine influenza
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OIE Reference Laboratory Reports Activities Activities in 2017 This report has been submitted : 2018-02-02 12:52:15 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Classical
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2016-12-30 08:33:00 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-20 16:19:13 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Foot
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OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-05-02 14:04:59 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: New
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OIE Reference aboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-30 12:18:25 Name of disease (or topic) for which you are a designated OIE Reference aboratory: Equine
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OIE Reference Laboratory Reports Activities Activities in 2014 This report h been submitted : 2015-01-12 10:32:19 Name of disee (or topic) for which you are a designated OIE Reference Laboratory: Swine
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OIE Reference Laboratory Reports Activities Activities in 2015 This report has been submitted : 2016-01-18 19:55:39 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Rabies
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OIE Reference Laboratory Reports Activities
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OIE Reference Laboratory Reports Activities
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OIE Collaborating Centers Reports Activities Activities in 2014 This report has been submitted : 2015-01-16 10:12:58 Title of collaborating centre: ELISA et les techniques moléculaires Address of Collaborating
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2014 This report has been submitted : 2015-01-21 18:05:29 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Rabies
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OIE Collaborating Centres Reports Activities Activities in 2017 This report has been submitted : 2017-12-13 11:14:09 Title of collaborating centre: Food-Borne Parasites from the Asia-Pacific Region Address
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2017 This report has been submitted : 2018-01-16 10:23:14 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Swine
OIE Reference Laboratory Reports Activities
OIE Reference Laboratory Reports Activities Activities in 2016 This report has been submitted : 2017-01-16 11:40:28 Name of disease (or topic) for which you are a designated OIE Reference Laboratory: Classical
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