TABLE OF CONTENTS TABLE OF CONTENTS

Transcription

1 I II III FOUNDATIONS 1. Embryology 3 2. Teratogenesis 5 3. Cell Biology: Organelles 7 4. Cell Biology: Cytoplasm and Cytoskeleton Cell Biology: Plasma Membrane Cellular Suffering and Death Inflammation Extracellular Environment Cellular Adaptations 22 NEUROLOGY 1. Organization of the Brain Hypothalamus Sleep Cranial Nerves part Cranial Nerves part Brain Embryology Regions of the Brain Brainstem in Cross Section Brainstem Lesions Vascular Events CSF Headache Brain Tumors Anesthetics Seizures Movement Basal Ganglia Spinal Cord and Lesions Brachial Plexus and Upper Extremity Nerves part Brachial Plexus and Upper Extremity Nerves part Lower Extremity and Skeletal Muscle Sensation Eye Ear Delirium and Dementia 91 PHARM BASICS 1. Parasympathetic Activation Parasympathetic Inhibition Sympathetic Activation Sympathetic Inhibition Neurotransmission G Protein Second Messengers Pharmacokinetics Pharmacodynamics Drug Metabolism Drug Elimination Drug Side Effects Antidotes 130 [ i ]

2 IV V VI CARDIOVASCULAR 1. Cardio Embryology Developmental Pathology Cardiac Output Heart Failure Treatment of CHF Edema and Shock Cardiac Cycle Diastolic Heart Murmurs Systolic Heart Murmurs Electrophysiology Antiarrhythmics Electrocardiography Arrhythmias Regulation of BP Hypertension Antihypertensives Atherosclerosis Antianginal Therapy and Lipid-Lowering Agents Myocardial Infarction part Myocardial Infarction part Cardiomyopathies and Endocarditis Other Cardiac Pathology Vascular Diseases 184 RHEUM & DERM 1. Bone Formation and Bone Tumors Bone Disorders Joint Basics Osteoarthritis and Rheumatoid Arthritis Other Types of Arthritis Systemic Disorders Dermatology part Dermatology part REPRODUCTION 1. Anatomy and Embryology Androgens Testicular Pathology Penis and Prostate Pathology Female Reproductive Cycle Birth Control and Menopause Vaginal and Cervical Pathology Uterine Pathology Ovarian Disorders Ovarian Tumors Pregnancy part Pregnancy part Pregnancy part Chromosomal Disorders Genetic Disorders: AD and Trinucleotide Repeats Genetic Disorders: AR and X-Linked Breast 245 [ ii ]

3 VII VIII MICRO 1. Bacterial Basics Bacterial Toxins Staphylococcus Streptococcus Other Gram Positive Bacteria Intro to Gram Negative Bacteria Diarrhea UTI Spirochetes and Zoonotics Mycobacteria Nonstaining Bacteria Penicillins Cephalosporins Other Cell Wall Inhibitors Protein Synthesis Inhibitors Other Antibiotics Micro by Systems part Micro by Systems part Viral Basics DNA Viruses part DNA Viruses part RNA Viruses part RNA Viruses part HIV HIV Drugs Mycology part Mycology part Antifungals Protozoa Helminths and Ectoparasites 316 IMMUNOLOGY 1. Immune System Basics Antigen Presentation T Cells B Cells and Antibodies Immunization and Autoantibodies Hypersensitivity and Complement Macrophages, Granulocytes and Cytokines Immunosuppressants Immunodeficiencies 335 [ iii ]

4 IX X XI GI 1. Oropharynx Esophagus Stomach Upper GI Path Duodenum Enterocytes and Absorption Diseases of Small Intestine Large Intestine part Large Intestine part Large Intestine part Pancreas Liver Basics Alcoholic Liver Disease and Cirrhosis Liver Pathology Hepatitis Biliary Tract 373 PULMONARY 1. Anatomy and Physiology Lung Volumes and Pulmonary Circulation Oxygen and Hemoglobin Oxygenation Ventilation and Perfusion Extreme Environments PE, DVT, and Pneumothorax COPD and Asthma Pulmonary Medications Restrictive Lung Disease Lung Cancer Lung Infections 403 MEDICINE IN SOCIETY 1. Research Study Designs Diagnostic Test Evaluation Interpretation of Study Data Study Validity Statistical Distribution and Error Biostatistics Public Health, Grief, and Geriatrics Healthcare System Ethics 429 [ iv ]

5 XII XIII XIV XV BIOCHEM 1. DNA Basics DNA Replication, Mutation, and Repair RNA Protein Synthesis Inheritance Genetic Lab Techniques Glycolysis Gluconeogenesis Glycogen Energy Metabolism HMP Shunt and Other Sugars Starvation and Malnutrition Lipids Amino Acids and Nitrogen Amino Acid Disorders Minerals Fat Soluble Vitamins and Antioxidants Water Soluble Vitamins 476 PSYCH 1. Psychology Child Psych Adolescent Psych Alcohol Abuse Substance Abuse Psychosis Antipsychotics Bipolar Disorder Depression Antidepressants Anxiety and Somatoform Disorders Ego Defense Mechanisms and Personality Disorders 504 RENAL 1. Renal Embryology and Anatomy Glomerular Physiology Nephron Physiology Diuretics Electrolyte Disorders Acid-Base Disorders Nephrosis and Nephritis Other Renal Pathology 526 PEDIATRICS 1. Pediatric Review 530 [ v ]

6 XVI ENDOCRINE 1. Endocrine Overview Pituitary Adrenal Steroid Synthesis Glucocorticoids and Cushing Syndrome Other Adrenal Pathology Thyroid Basics and Hyperthyroidism Hypothyroidism and Thyroid Cancer Diabetes DKA and Diabetes Treatment Obesity Calcium Metabolism 558 XVII HEME 1. Clotting Factors Anticoagulant Drugs RBC Basics Erythropoiesis Nonhemolytic Anemias Hemolytic Anemias Platelet Function Platelet Disorders Lymphoma Leukemia and Multiple Myeloma 581 XVIII ONCOLOGY 1. Genetics of Cancer Cancer Risk Factors Tumor Nomenclature Neoplastic Progression Cancer Prevention and Host Defense Cancer Drugs part Cancer Drugs part [ vi ]

7 NOTES NOTES KEY TO ABBREVIATIONS This Study Guide contains page references to several medical educational resources. Below is a key to the abbreviations that accompany the various page number references appearing in this text. FA14 FA13 SU14 Phys R COA H GG Le, T, Bhushan, V, et al. First Aid for the USMLE Step New York, NY: McGraw-Hill; Le, T, Bhushan, V, et al. First Aid for the USMLE Step New York, NY: McGraw-Hill; Jenkins, B, et al. Step-Up to USMLE Step Philadelphia, PA: Lippincott Williams & Wilkins; 2013 Hall, JE. Guyton and Hall Textbook of Medical Physiology. 12th ed. Philadelphia, PA: Saunders Elsevier; Kumar, V, Abbas, AK, et al. Robbins and Cotran Pathologic Basis of Disease. 8th ed. Philadelphia, PA: Saunders Elsevier; Moore, KL, Dalley, AF, & Agur, AMR. Clinically Oriented Anatomy. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; Longo, DL, Fauci, AS, Kasper, DL, Hauser, SL, Jameson, JL, Loscalzo, J, eds. Harrison s Principles of Internal Medicine. Vol th ed. New York, NY: McGraw-Hill; Brunton, LL, Chabner, BA, & Knollman, BC, eds. Goodman & Gilman s The Pharmacological Basis of Therapeutics. 12th ed. New York, NY: McGraw-Hill; COURSE VIEWING OPTIONS Part 2 consists of 237 videos. Examples of 15, 18, 21, 24, and 30-day plans are provided below for maximum flexibility to meet your personal study needs. No. of Videos/Day Video Runtime/Day* 15-day plan 16 Approx. 5.5 hrs 18-day plan 13 Approx. 4.5 hrs 21-day plan 11 Approx. 4 hrs 24-day plan 10 Approx. 3.5 hrs 30-day plan 8 Approx. 2.5 hrs *Does not include study breaks or time spent annotating and answering questions. [ vii ]