Annual Academic Meeting (Incorporating the Annual Blair Bell Research Society Competition) Joint RCOG/Blair Bell Research Society

Transcription

1 Annual Academic Meeting (Incorporating the Annual Blair Bell Research Society Competition) Joint RCOG/Blair Bell Research Society Programme Thursday 8 February am 10.00am REGISTRATION AND REFRESHMENTS Welcome Professor Andrew Horne, Chair, RCOG Academic Board Session I: Free Communications Chairs: Professor Andrew Horne Dr Jenny Myers, Clinical Senior Lecturer, University of Manchester 10.15am 10.30am 10.45am 11.00am Hydroxychloroquine ameliorates FGR-associated free fetal haemoglobin evoked fetoplacental vasoconstriction and protects against fhbf-induced endothelial cell dysmorphology Mr Adam Brook, Specialist Registrar, Academic Clinical Fellow, University of Manchester PRE-surgical metformin in uterine malignancy-results of the PREMIUM randomised controlled trial Ms Sarah Kitson, Clinical Research Fellow, University of Manchester, Division of Cancer Sciences An investigation of familial predisposition to stillbirth using mother-daughter pairs: an intergenerational case-control study using routinely collected hospital data in Aberdeen, UK Ms Andrea Woolner, SCREDS Clinical Lecturer / Honorary ST4, University of Aberdeen Aberrant activation of the hedgehog signalling pathway in highgrade serous ovarian cancer (HGSOvCa): a potential therapeutic target Ms Rachel Pounds, OVACOME Clinical Research Fellow, University of Birmingham Session II: Keynote Lecture Chair: Mr Nigel Simpson, Clinical Senior Lecturer, University of Leeds 11.15am 11.45am Babies, bugs and biomarkers Professor Phillip Bennett, Professor of Obstetrics and Gynaecology; Honorary Consultant Obstetrician and Gynaecologist, Imperial Healthcare NHS Trust

2 Programme Thursday 8 February pm Career advice drop in session: Medical Students Pre-PhD/Early PhD Late PhD/Post-PhD Scientists Session III: Pitch Your Poster Chairs: Dr Fiona Denison, Reader, University of Edinburgh Dr Neil Ryan, Clinical Research Fellow Fast paced session where the authors of highest scoring posters have a chance to promote their poster to the audience with the use of one PowerPoint slide and questions from the audience (3 Gynae and 3 Obs) 12.30pm 12.35pm 12.40pm 12.45pm 12.50pm 1.00pm The vaginal microbiota and the adaptive immune system in pregnant and non-pregnant women Ms Denise Chan, Clinical Research Fellow, Imperial College, London Can previous obstetric history influence preterm birth prevention treatment in a subsequent pregnancy? A comparison of vaginal progesterone and arabin pessary Dr Angharad Care, Harris-Wellbeing Preterm Birth Clinical Research Fellow, University of Liverpool, Liverpool Women's Hospital The fetal PR interval is significantly elongated in severe intrahepatic cholestasis of pregnancy as measured by transabdominal fetal electrocardiography Miss Tharni Vasavan, PhD Student, King's College, London TLR3 priming increases TLR4- and TLR6-mediated proinflammatory cytokine production in amniocytes, myocytes and vaginal epithelial cells Miss Zahirrah Mohamed Rasheed, PhD Student, Imperial College, London Manufacturing clinical-grade human amniotic fluid stem cells for translational regenerative medicine applications Eleni Antomiadou, PhD Student, Department of Regenerative Medicine and Stem Cells, University College London, Great Ormond Street Institute of Child Health, London LUNCH with POSTER VIEWING and JUDGING Session IV: Keynote Lecture Chair: Professor Andrew Horne 2.00pm The future for genetic studies in reproduction Professor Krina Zondervan, Professor of Reproductive and Genomic Epidemiology, University of Oxford

3 Programme Thursday 8 February 2018 Session V: Post-doctoral research Chair: Dr Jenny Myers 2.50pm 3.10pm 3.15pm 3.35pm 3.40pm Dissecting human embryo implantation using in vitro models Dr Peter Ruane, Research Associate, University of Manchester Chronic fetal hypoxia and ovarian reserve Dr Catherine Aiken, Academic Clinical Lecturer, Department of Obstetrics and Gynaecology, University of Cambridge Session VI: Free Communications Chairs: Dr Ian Crocker, Senior Lecturer, University of Manchester Dr Emma Crosbie, Clinical Senior Lecturer, University of Manchester 4.00pm 4.15pm 4.30pm 4.45pm Cervical gene delivery of human beta-defensin-3 (HBD-3) prevents E.coli K1 ascending bacterial infection and increases the proportion of live births in pregnant mice Ms Natalie Stuff, Clinical Research Fellow, Institute for Women s Health, Univerisity College London 3D Architecture of endometrial glands in relation to stem cell organisation Ms Nicola Tempest Targeted delivery of sflt-1e15a-specific sirna to the placental syncytiotrophoblast via liposomes Miss Chloe Logue, Mres, Maternal and Fetal Health Research Centre, St Mary's Hospital / Manchester University Chronic endometritis and recurrent reproductive failure Mr Michael Rimmer, Academic Clinical Fellow in Obstetrics and Gynaecology, University of Warwick and University Hospitals Coventry and Warwickshire, Warwick

4 Programme Thursday 8 February 2018 Session VII: Academic prize giving ceremony Chair: Professor Andrew Horne 5.00pm RCOG Academic Awards Presentation and talk by winner of RCOG Academic Award pm 6.00pm How I learned to be positive about negative Professor Zarko Alfirevic, Head of Department of Women s and Children s Health, University of Liverpool DRINKS RECEPTION Networking Informal networking areas will be available during the drinks reception to offer an opportunity to speak with senior academics. Signposted areas will be available for: Clinical Research in Obstetrics Laboratory Basic research Science Obstetrics Clinical Research Gynaecology Basic Science Gynaecology 7.30pm CLOSE

5 Programme Friday 9 February am 9.00am Blair Bell Research Society Annual General Meeting REGISTRATION AND REFRESHMENTS Session VIII: Free communications Chairs: Professor Lucy Chappell, NIHR Research Professor, Kings College London Dr Emma Crosbie 9.15am 9.30am 9.45am 10.00am Vitamin-D and fetomaternal immunity: next generation RNA sequence analysis reveals unique effects upon uterine natural killer cells Ms Jennifer Tamblyn, Clinical Research Fellow Obstetrics & Gynaecology University of Birmingham Circulating Tumour DNA as a Diagnostic Biomarker in High-grade serous ovarian cancer Ms Elizabeth Moore, Clinical Fellow, Addenbrooke's Hospital, Cambridge Rapid mucosal metabolome profiling by desorption electrospray ionization MS (DESI-MS) for prediction of preterm pre-labour rupture of membranes (PPROM) Ms Holly Lewis, Clinical Research Fellow, Imperial College London Could gonadotrophin releasing hormone receptor antagonists be repurposed to treat women with ectopic pregnancy? Ms Lisa Campbell, Wellcome Trust Clinical Research Fellow, Centre for Reproductive Health, University of Edinburgh Session IX: Post-doctoral research Chair: Dr Katy Vincent, Senior Clinical Lecturer, University of Oxford 10.15am 10.35am 10.40am 11.00am 11.05am Bovine implantation and implications for human implantation Dr Niamh Forde, University Academic Fellow and Principal Investigator in Reproduction and Early Development, University of Leeds VIN treatment Dr Sadie Jones, Welsh Clinical Academic Trainee, Royal Gwent Hospital, Newport, Wales

6 Programme Friday 9 February 2018 Session X: Pitch your poster Chair: Professor Louise Kenny, University College Cork and Dr Neil Ryan Fast paced session where the authors of highest scoring posters have a chance to promote their poster to the audience with the use of one PowerPoint slide and questions from the audience (3 Gynae and 3 Obs) 11.30am 11.35am 11.40am 11.45am 11.50am 11.55am 12.00pm Understanding the mechanisms through which repetitive cyclic tensile strain leads to human fetal membrane weakening Mr David Barrett, PhD Student, Queen Mary University of London Exploring the role of macrophage sub-populations in the aetiology of endometriosis Ms Chloe Hogg, PhD Student, Centre for Reproductive Health, University of Edinburgh A high third trimester sflt-1:plgf ratio is associated with reduced fetal growth velocity Ms Lucy Higgins, NIHR Academic Clinical Lecturer in Obstetrics, University of Manchester Unravelling the steroid metabolome in epithelial ovarian cancer Dr David Jeevan, Wellbeing of Women Clinical Research Fellow, Institute of Metabolism and Systems Research, University of Birmingham Are first trimester ultrasound measurements and maternal serum biomarkers prognostic factors of adverse outcomes in monochorionic twins? The OMMIT study Ms Fiona Mackie, 3rd Year PhD Student, Clinical Research Fellow, University of Birmingham / Birmingham Women's and Children's NHS Foundation Trust Shock index thresholds to predict adverse outcomes in maternal haemorrhage and sepsis: a prospective cohort study Ms Hannah Nathan, ST2 Obstetrics and Gynaecology Trainee and PhD Student, King s College Hospital, London LUNCH with POSTER VIEWING and JUDGING Session XI Chair: Dr Jenny Myers 1.30pm A scientist s perspective of translational research in reproductive biology Professor Colin Sibley, Professor of Child Health and Physiology; Research Director, Manchester Academic Health Science Centre, University of Manchester

7 Programme Friday 9 February 2018 Session XII: Clinical study group breakout groups Please choose one of the below breakout sessions. 2.15pm Gynaecology clinical study groups current activity and ways to get involved Obstetric clinical study groups current activity and ways to get involved BJOG Improving your publishing 3.15pm Session XIII Chair: Professor Lucy Chappell 3.30pm 4.15pm 4.30pm William Blair Bell Memorial Lecture Population based Germline Testing and Targeted Ovarian cancer prevention Dr Ranjit Manchanda, Clinical Senior Lecturer and Consultant Gynaecological Oncologist, Barts Cancer Institute, Queen Mary University of London and Barts Health NHS Trust Presentation of winners of Blair Bell Research Society competition CLOSE 7