NEWCASTLE FORUM 7 9 June 2017

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1 NEWCASTLE FORUM 7 9 June 2017 Hunter Medical Research Institute Newcastle, Australia PROGRAM

2 Contents WELCOME MESSAGE 3 PROGRAM OF EVENTS 4-8 KEYNOTE SPEAKERS 9 ABSTRACTS SPONSORS 13 VENUE INFORMATION 14 ACCOMMODATION 15 REGISTRATION 16 NEWCASTLE FORUM 7-9 JUNE

Welcome Message We are delighted to welcome you to the NHMRC Centre of Research Excellence (CRE) in Stroke Rehabilitation and Brain Recovery Newcastle Forum.

3 Welcome Message We are delighted to welcome you to the NHMRC Centre of Research Excellence (CRE) in Stroke Rehabilitation and Brain Recovery Newcastle Forum. This forum is organised by the CRE in Stroke Rehabilitation and Brain Recovery in collaboration with the Hunter Medical Research Institute, The Florey Institute of Neuroscience and Mental Health and the University of Newcastle. The CRE in Stroke Rehabilitation and Brain Recovery aims to support the transformation of the stroke research and practice landscape in Australia by developing new treatments, improving patient selection into clinical trials and advancing rehabilitation research methods. The CRE spans across a number of streams being, basic science, imaging, clinical trials, implementation research and data linkage. The CRE Newcastle Forum coincides with Medical Research Week and we are fortunate to hear from keynote speakers, Professor Mark Bayley (University of Toronto, Canada) and Dr Peter Thomas (Director, Policy and Operations, AAMRI), attracting a broad audience as they share their expertise in implementation science, the importance of translational research in addition to current and future research policies in Australia. We will also hear from our CRE Stream Leaders and associated researchers as they share their work and progress in addition to Industry Partners involved in stroke research and practice. We hope to have rewarding discussions as we further explore collaborative opportunities working towards the next phase in the CRE and our goals and outcomes. Welcome! Prof Julie Bernhardt Prof Michael Nilsson NEWCASTLE FORUM 7-9 JUNE

4 Program of Events All sessions are free to attend. Please note some sessions are for CRE Members / Management only. A CRE Member is a Chief Investigator, Associate Investigator, Research Affiliate or students officially registered with the CRE for collaboration purposes. Wednesday 7 June TIME SESSION 4.30pm 5.00pm Pre-seminar refreshments Haggarty, HMRI 5.00pm 5.10pm HMRI Medical Research Week Seminar Opening and Welcome Prof Michael Nilsson Director, HMRI Caves Theatre, HMRI O P E N S E M I N A R 5.10pm 6.05pm 6.05pm 7.00pm Implementing Evidence into Practice in The Age of Alternative Facts A review of knowledge translation and implementation science and what clinicians and researchers can learn from marketers, behavioural economists and even politicians about changing practice Prof Mark Bayley University of Ontario, Canada Supporting the Health and Medical Research Continuum A review of the current and future research funding landscapes and what policy issues need to be addressed to ensure strong health and medical research continuum in Australia. Dr Peter Thomas Director, Policy & Operations, AAMRI 7.00pm 7.30pm Light refreshments Haggarty, HMRI NEWCASTLE FORUM 7-9 JUNE

5 Program of Events Thursday 8 June TIME SESSION 8.30am 9.00am Registration Haggarty, HMRI C R E M E M B E R O N L Y 9.00am 10.45am CRE in Stroke Rehabilitation and Brain Recovery Streams: Mid-term overview - achievements & challenges Stream leader overviews: Basic Science, Imaging, Clinical Trials, Implementation Research and Data Linkage 20min per stream FACILITATOR Prof Geoff Donnan Caves Theatre, HMRI 10.45am 11.00am Morning Tea Haggarty, HMRI 11.00am 12.45pm CRE in Stroke Rehabilitation and Brain Recovery Streams: Mid-term overview - achievements & challenges (cont.) Stream leader overview recap 10min Research impact overview 20min (Dr Shanthi Ramanathan) Research Implementation summary 20min (Dr Liz Lynch) Summary and Discussion 55min FACILITATOR Prof Geoff Donnan Caves Theatre, HMRI NEWCASTLE FORUM 7-9 JUNE

6 Program of Events Thursday 8 June (cont.) TIME SESSION 12.45pm 1.15pm Lunch (Open session Registration) Haggarty, HMRI 1.15pm 2.00pm Keynote Lecture Walking through the Valley of Death Between Research and Practice and Living to Tell About It Caves Theatre, HMRI A review of experience implementing stroke evidence into practice Prof Mark Bayley University of Ontario, Canada CHAIR Prof Julie Bernhardt O P E N S E S S I O N 2.00pm 4.00pm The National Vision CRE in Stroke Rehabilitation and Brain Recovery: What is it? What has it done? What can it do? CRE Overview - (CRE Co-directors, Prof Julie Bernhardt and Prof Michael Nilsson (30mins)) International Landscape What needs to happen in rehabilitation? (Prof Mark Bayley (15mins)) Transformational Research & Practice What are the future directions and can the CRE be part of the solution? (Prof Julie Bernhardt (15mins)) Collaborative Gains & Challenges Global Sedentary Behaviour Collective (A/Prof Coralie English (15mins)) Australian Stroke Research Network Survey results (Dr Karen Borschmann (10mins)) Industry overviews What is happening in your space? (Industry representatives (15mins)) Open Discussion Are we on track to achieve what we set out to do? (20mins) - What else can be done? - How can we better engage with the community and our industry partners? - What threats do we need to consider? - What opportunities do we need to grasp? - How best to position the CRE for the future? MODERATORS Prof Julie Bernhardt, Prof Michael Nilsson, A/Prof Andrew Searles & A/Prof Michael Pollack Caves Theatre, HMRI NEWCASTLE FORUM 7-9 JUNE

7 Program of Events Thursday 8 June (cont.) TIME SESSION 4.00pm 4.15pm Afternoon Tea Haggarty, HMRI OPEN SESSION 4.15pm 5.15pm Three Minute Research Snapshot Competition CRE students are invited to present their work and research highlights (Prizes awarded at the conclusion) SCIENTIFIC PANEL MEMBERS A/Prof Rohan Walker (Basic Science), A/Prof Coralie English (Clinical Trials), Prof Leeanne Carey (Imaging), A/Prof Dominique Cadilhac (Implementation Science and Data Linkage) Caves Theatre, HMRI 5.15pm 6.15pm Networking Function Haggarty, HMRI CRE MANAGEMENT 6.30pm 10.00pm CRE Management Committee Dinner Newcastle Club 40 Newcomen Street, Newcastle NEWCASTLE FORUM 7-9 JUNE

8 Program of Events Friday 9 June TIME 8.30am 9.00am SESSION Registration Haggarty, HMRI 9.00am 10.30am CRE MANAGEMENT CRE in Stroke Rehabilitation and Brain Recovery Management and Steering Committee Meeting CHAIR Prof Julie Bernhardt and Prof Michael Nilsson, CRE Co-Directors Moss Room, HMRI OPEN SESSION Concurrent Open Workshop Starting with the end in mind: a workshop to promote integration of knowledge translation and implementation principles into all research Early Mid Career Implementation Research Workshop Prof Mark Bayley University of Ontario, Canada FACILITATORS Dr Shanthi Ramanathan & Dr Liz Lynch Caves Theatre, HMRI 10.30am 11.00am Morning Tea Haggarty, HMRI 11.00am 12.30pm CRE MEMBERS CRE in Stroke Rehabilitation and Brain Recovery: next phase in today s translational research landscape - Future / Emerging Leaders - CRE strategy for the next phase FACILITATOR Prof Geoff Donnan Caves Theatre, HMRI 12.30pm 1.15pm Light Lunch Haggarty, HMRI NEWCASTLE FORUM 7-9 JUNE

Keynote Speakers Professor Mark Bayley MD FRCPC Dr Mark Bayley is a Professor in the Division of Physical Medicine and Rehabilitation, Department of Medicine at the University of Toronto, Canada.

Institute of the University Health Network.

9 Keynote Speakers Professor Mark Bayley MD FRCPC Dr Mark Bayley is a Professor in the Division of Physical Medicine and Rehabilitation, Department of Medicine at the University of Toronto, Canada. He is the holder of the Saunderson Family Chair in Brain Injury Research, Senior Scientist and Medical Director of the Brain and Spinal Cord rehabilitation Program at the Toronto Rehabilitation Institute of the University Health Network. Dr Bayley has a strong research interest in implementation science, in particular, how the best scientific evidence is implemented into practice and how to measure its uptake by clinicians. He has authored a number of clinical practice guidelines and led expert panels. Examples of his work include the Canadian Stroke Best Practice Guidelines ( the INCOG-International Cognitive rehabilitation guidelines, the Evidence Based review of the Acquired Brain injury Rehabilitation ( the Ontario Neuro Trauma Foundation (ONF-INESS) best practice guidelines ( Best Practice Guidelines for the Management of Persistent Symptoms after Mild Traumatic Brain injury ( He also has extensive experience in implementation activities in his role as evaluation leader for the Ontario Stroke System, principal investigator of The Stroke Canada Optimization of Rehabilitation by Evidence Implementation Trial (SCORE-IT), the Viatherapy smartphone app for stroke recovery ( and the Rick Hansen Institute SCI HIGH project that develops indicators for Spinal Cord Injury Care. He is also actively involved in the evaluation of technology and novel models of rehabilitation care, designed to enhance neurological recovery after brain injury using randomized controlled trials including, the Getting on with Life after Stroke and the EVREST (Efficacy of Virtual Reality Exercises using Wii gaming technology in Stroke Rehabilitation) and the Evaluation of the Myndmove Functional Electrical stimulation device for arm recovery. Dr Peter Thomas Peter is the Director of Policy and Operations at the Association of Australian Medical Research Institutes (AAMRI). He has extensive experience in science policy, strategy, and government relations. He oversees the development of AAMRI s policy documents and submissions, member services, government and external stakeholder relations, and AAMRI s day-to-day operations. Peter was recently a coauthor of the Government commissioned ACOLA Review of Research Training. NEWCASTLE FORUM 7-9 JUNE

10 Abstracts Wednesday 7 June HMRI Medical Research Week Seminars Implementing Evidence into Practice in the Age of Alternative Facts Prof Mark Bayley, University of Ontario, Canada A review of knowledge translation and implementation science and what clinicians and researchers can learn from marketers, behavioural economists and even politicians about changing practice. The gap between publication of new evidence and implementation into practice is estimated to be about 17 years and of that only a portion of the evidence is implemented into practice. While not all evidence is worthy of implementation, there remain significant challenges finding strategies that are consistently effective for changing clinical practice when necessary. Knowledge translation and implementation is highly context specific and therefore must result from a thoughtful planned process that is tailored to the situation. This presentation will review the evidence behind current approaches for implementation and some of the challenges in the research in the field. By the end of the presentation, participants should be able to: 1. Discuss the key steps in a model for implementing knowledge into practice. 2. Name at least 3 sources of barriers to implementation of evidence into practice. 3. Discuss some implementation strategies based on implementation research and behavioural theory including those derived from the fields of economics and marketing that could be adapted to increase the uptake of evidence in practice. Supporting the Health and Medical Research Continuum Dr Peter Thomas, Director of Policy and Operations, AAMRI There are significant changes that are set to affect how health and medical research is structured and funded in Australia. The first is the $20 billion Medical Research Future Fund (MRFF), and the second is the Structural Review of NHMRC s Grant Program. The MRFF is set to deliver around $1 billion in additional health and medical research funding by 2021, effectively doubling the Australian Government s annual investment in health and medical research. The NHMRC Structural Review has the potential to change how investigator-led research is supported. These changes provide immense opportunities, but careful consideration and planning is needed to ensure maximum benefits can be realised. Ensuring funding duplication is avoided, support reaches the highest quality projects, and developing a strong research pipeline from lab-based discoveries through to the development of new drugs and treatments for patients are just a few of the policy areas that need careful consideration. This paper explores these issues and looks to see what policy issues need to be addressed to ensure strong health and medical research continuum in Australia. NEWCASTLE FORUM 7-9 JUNE

11 Abstracts Thursday 8 June CRE Forum Keynote Walking Through the Valley of Death Between Research and Practice and Living to Tell About It Prof Mark Bayley, University of Ontario, Canada A review of experience implementing stroke evidence into practice There are over 1000 randomized control trials in the field of stroke rehabilitation but many important research questions remain and unfortunately much of this evidence has not been implemented into practice. Two valleys of death have been identified where medical research stalls: the first from basic science into human studies and the second from human trials in to day to day clinical practice and health policy. This presentation will review a number of initiatives to implement stroke rehabilitation research in the Canadian and international context. These initiatives include: building consensus as to research and knowledge translation priorities, the challenges of synthesizing rehabilitation evidence into guidelines that are user-friendly, examples of integrating research to practice clinics locally, executing a large pan-canadian cluster randomized implementation trial and strategies that have been used at a population level in Canada to change stroke system performance. By the end of the session participants should be able to: 1. Discuss how stroke research evidence can be improved and how evidence can be synthesized and tailored in a way to make it easier for clinicians to use. 2. Identify some implementation strategies that have been evaluated in the stroke rehabilitation context that could be adopted in Australia 3. Name 2 or 3 strategies that could be used to influence health system leaders and funders support for best practice implementation NEWCASTLE FORUM 7-9 JUNE

12 Abstracts Friday 9 June Concurrent Open Workshop Starting with the End in Mind: A Workshop to Promote Integration of Knowledge Translation and Implementation Principles into all Research One of the challenges of knowledge translation is that researchers in stroke rehabilitation need to consider how the evidence that they are developing will ultimately be used. This workshop is designed for researchers who are interested in improving the uptake of their research and also better understanding the field of implementation science. NB: Researchers are encouraged to bring one or two examples of their research underway that could be used as specific content to work through the workshop exercises. During the workshop, participants will: 1. Use a framework to identify barriers to implementation of their research ideas and innovations. 2. Identify the target users of the knowledge they are developing and the changes in the target users behaviour that are necessary for successful implementation. 3. Develop some implementation science research questions including: a. Selecting some qualitative and/or quantitative strategies for evaluating the extent of implementation; and b. Selecting potential feasible methodologies for acquiring data to answer these questions. NEWCASTLE FORUM 7-9 JUNE

13 Sponsors NEWCASTLE FORUM 7-9 JUNE

Venue Information Hunter Medical Research Institute Kookaburra Circuit, New Lambton (Behind John Hunter Hospital) Newcastle, Australia Ph: +61 2 4042 0000

14 Venue Information Hunter Medical Research Institute Kookaburra Circuit, New Lambton (Behind John Hunter Hospital) Newcastle, Australia Ph: lucy.bailey@hmri.org.au Note: Limited parking is available on site so please advise if you require a reserved car space NEWCASTLE FORUM 7-9 JUNE

15 Accommodation Recommended hotels in Newcastle include: The Executive Inn 10 Rugby Road, New Lambton Ph: Located within approx. 3km of conference venue Apollo Hotel Newcastle 290 Pacific Highway, Charlestown Ph: Located within approx. 8km of conference venue Crown Plaza Newcastle Cnr Wharf Road & Merewether Street, Newcastle Ph: Located within approx. 9km of conference venue Novotel Newcastle Beach 5 King Street, Newcastle Ph: Located within approx. 10km of conference venue NEWCASTLE FORUM 7-9 JUNE

16 Registration You can register for the CRE in Stroke Rehabilitation and Brain Recovery Newcastle Forum by CLICKING HERE. All sessions are free to attend. Please note some sessions are for CRE Members / Management only. A CRE Member is a Chief Investigator, Associate Investigator, Research Affiliate or students officially registered with the CRE for collaboration purposes. If you have issues with online registration or any enquiries please contact: Lucy Bailey, lucy.bailey@hmri.org.au Jan Chamberlain, janmc@unimelb.edu.au NEWCASTLE FORUM 7-9 JUNE

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